thyroxine has been researched along with Angiogenesis, Pathologic in 23 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim was to evaluate tetraiodothyroacetic acid (tetrac), a thyroid hormone analog of L-thyroxin, conjugated to poly(lactic-co-glycolic acid) nanoparticles (T-PLGA-NPs) both in vitro and in vivo for the treatment of drug-resistant breast cancer." | 7.79 | Tetraiodothyroacetic acid-conjugated PLGA nanoparticles: a nanomedicine approach to treat drug-resistant breast cancer. ( Bharali, DJ; Davis, PJ; Mousa, SA; Yalcin, M, 2013) |
| "These data indicate that the cardiac hypertrophy induced by acute treatment with thyroid hormone precedes the angiogenic process, which probably occurs later." | 5.33 | Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density. ( Anjos-Ramos, L; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Martins-Silva, J, 2006) |
| "The aim was to evaluate tetraiodothyroacetic acid (tetrac), a thyroid hormone analog of L-thyroxin, conjugated to poly(lactic-co-glycolic acid) nanoparticles (T-PLGA-NPs) both in vitro and in vivo for the treatment of drug-resistant breast cancer." | 3.79 | Tetraiodothyroacetic acid-conjugated PLGA nanoparticles: a nanomedicine approach to treat drug-resistant breast cancer. ( Bharali, DJ; Davis, PJ; Mousa, SA; Yalcin, M, 2013) |
| "Human pancreatic cancer cell (PANC-1 and MPanc96) xenografts were established in nude mice, and the effects of tetrac versus Tetrac NP on tumor growth and tumor angiogenesis were determined." | 1.39 | Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles. ( Bharali, DJ; Davis, FB; Davis, PJ; Lin, HY; Meng, R; Mousa, SA; Stain, SC; Sudha, T; Tang, HY; Yalcin, M, 2013) |
| "Renal cell carcinoma is the most lethal of the common urologic malignancies, with no available effective therapeutics." | 1.35 | Tetraidothyroacetic acid (tetrac) and tetrac nanoparticles inhibit growth of human renal cell carcinoma xenografts. ( Bharali, DJ; Davis, FB; Davis, PJ; Dyskin, E; Hercbergs, A; Lansing, L; Mousa, SA; Mousa, SS; Yalcin, M, 2009) |
| "These data indicate that the cardiac hypertrophy induced by acute treatment with thyroid hormone precedes the angiogenic process, which probably occurs later." | 1.33 | Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density. ( Anjos-Ramos, L; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Martins-Silva, J, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.04) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 13 (56.52) | 24.3611 |
| 2020's | 2 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Schmohl, KA | 3 |
| Müller, AM | 2 |
| Nelson, PJ | 3 |
| Spitzweg, C | 3 |
| Kim, H | 1 |
| Koo, HJ | 2 |
| Ahn, J | 1 |
| Kim, JY | 1 |
| Choi, JY | 1 |
| Lee, KH | 1 |
| Kim, BT | 1 |
| Choe, YS | 2 |
| Sudha, T | 2 |
| Bharali, DJ | 5 |
| Sell, S | 1 |
| Darwish, NHE | 1 |
| Davis, PJ | 7 |
| Mousa, SA | 7 |
| Rajabi, M | 1 |
| Yalcin, M | 5 |
| Latteyer, S | 1 |
| Christoph, S | 1 |
| Theurer, S | 1 |
| Hönes, GS | 1 |
| Schmid, KW | 1 |
| Führer, D | 1 |
| Moeller, LC | 1 |
| Lin, HY | 3 |
| Meng, R | 1 |
| Tang, HY | 1 |
| Davis, FB | 4 |
| Stain, SC | 1 |
| Kang, CM | 1 |
| Lee, S | 1 |
| Lee, KC | 1 |
| Oh, YK | 1 |
| Wechselberger, A | 1 |
| Rühland, S | 1 |
| Salb, N | 1 |
| Schwenk, N | 1 |
| Heuer, H | 1 |
| Carlsen, J | 1 |
| Göke, B | 1 |
| Corssac, GB | 1 |
| de Castro, AL | 1 |
| Tavares, AV | 1 |
| Campos, C | 1 |
| Fernandes, RO | 1 |
| Ortiz, VD | 1 |
| Siqueira, R | 1 |
| Fernandes, TR | 1 |
| Belló-Klein, A | 1 |
| Araujo, AS | 1 |
| Tu, Y | 1 |
| Wang, Y | 1 |
| Ding, L | 1 |
| Zhang, J | 1 |
| Wu, W | 1 |
| Sabatino, L | 1 |
| Kusmic, C | 1 |
| Nicolini, G | 1 |
| Amato, R | 1 |
| Casini, G | 1 |
| Iervasi, G | 1 |
| Balzan, S | 1 |
| Hercbergs, A | 2 |
| Lansing, L | 2 |
| Dyskin, E | 2 |
| Mousa, SS | 2 |
| Bridoux, A | 1 |
| Hercbergs, AH | 1 |
| Glinsky, GV | 1 |
| Glinskii, A | 1 |
| Ma, J | 1 |
| SOULAIRAC, A | 1 |
| CAHN, J | 1 |
| BARON, J | 1 |
| Anjos-Ramos, L | 1 |
| Carneiro-Ramos, MS | 1 |
| Diniz, GP | 1 |
| Martins-Silva, J | 1 |
| Barreto-Chaves, ML | 1 |
| Leonard, JL | 1 |
| Ryan, U | 1 |
| Slavkin, H | 1 |
| Revel, JP | 1 |
| Massaro, D | 1 |
| Gail, D | 1 |
| Rongish, BJ | 1 |
| Torry, RJ | 1 |
| Tomanek, RJ | 2 |
| Rakusan, K | 1 |
| Chilian, WM | 1 |
| Wangler, RD | 1 |
| Peters, KG | 1 |
| Marcus, ML | 1 |
5 reviews available for thyroxine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Thyroid Hormone Effects on Mesenchymal Stem Cell Biology in the Tumour Microenvironment.
Topics: Animals; Humans; Integrin alphaVbeta3; Mesenchymal Stem Cells; Neoplasms; Neovascularization, Pathol | 2020 |
Tetrac as an anti-angiogenic agent in cancer.
Topics: Angiogenesis Inhibitors; Animals; Humans; Mesenchymal Stem Cells; Neoplasms; Neovascularization, Pat | 2019 |
Possible contributions of thyroid hormone replacement to specific behaviors of cancer.
Topics: Animals; Apoptosis; Hormone Replacement Therapy; Humans; Hypothyroidism; Neoplasms; Neovascularizati | 2016 |
Mechanisms of nongenomic actions of thyroid hormone.
Topics: Actins; Animals; Cell Line, Tumor; Cell Proliferation; Genome; Humans; Integrin alphaVbeta3; Mitogen | 2008 |
Coronary angiogenesis. From morphometry to molecular biology and back.
Topics: Aging; Animals; Capillaries; Coronary Vessels; Growth Substances; Heart; Humans; Inflammation; Model | 1995 |
18 other studies available for thyroxine and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Synthesis and characterization of
Topics: Animals; Brain Neoplasms; Carbocyanines; Cells, Cultured; Copper Radioisotopes; Humans; Mice; Mice, | 2020 |
Nanoparticulate Tetrac Inhibits Growth and Vascularity of Glioblastoma Xenografts.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Hypothyroidism; Inte | 2017 |
Synthesis of new analogs of tetraiodothyroacetic acid (tetrac) as novel angiogenesis inhibitors for treatment of cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; | 2018 |
Thyroxine promotes lung cancer growth in an orthotopic mouse model.
Topics: Animals; Apoptosis; Carcinoma, Lewis Lung; Cell Proliferation; Hypothyroidism; Male; Mice; Mice, Inb | 2019 |
Tetraiodothyroacetic acid-conjugated PLGA nanoparticles: a nanomedicine approach to treat drug-resistant breast cancer.
Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxo | 2013 |
Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles.
Topics: Animals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic | 2013 |
64Cu-Labeled tetraiodothyroacetic acid-conjugated liposomes for PET imaging of tumor angiogenesis.
Topics: Animals; Cattle; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Drug Stabi | 2013 |
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentia | 2015 |
Thyroid hormones effects on oxidative stress and cardiac remodeling in the right ventricle of infarcted rats.
Topics: Animals; Echocardiography; Hydrogen Peroxide; Hypertrophy, Right Ventricular; Myocardial Infarction; | 2016 |
Development of a Novel Thyroid Function Fluctuated Animal Model for Thyroid-Associated Ophthalmopathy.
Topics: Animals; Body Weight; Disease Models, Animal; Drug Administration Schedule; Endoplasmic Reticulum; G | 2016 |
T3 enhances Ang2 in rat aorta in myocardial I/R: comparison with left ventricle.
Topics: Angiopoietin-2; Animals; Aorta; Disease Models, Animal; Echocardiography; Endothelial Cells; Gene Ex | 2016 |
Tetraidothyroacetic acid (tetrac) and tetrac nanoparticles inhibit growth of human renal cell carcinoma xenografts.
Topics: Animals; Carcinoma, Renal Cell; Cell Growth Processes; Cell Line, Tumor; Chick Embryo; Chorioallanto | 2009 |
Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Medullary; Cells, Cultured; Chick Embryo; Ch | 2010 |
[Protective action of D-thyroxin on disorders of ocular vascularization induced in the rabbit by an experimental hypercholesterolemic hyperlipemia].
Topics: Animals; Eye; Hypercholesterolemia; Hyperlipidemias; Neovascularization, Pathologic; Rabbits; Retina | 1963 |
Early cardiac hypertrophy induced by thyroxine is accompanied by an increase in VEGF-A expression but not by an increase in capillary density.
Topics: Animals; Capillaries; Cardiomegaly; Coronary Vessels; Disease Models, Animal; Dose-Response Relation | 2006 |
Conference report: cell-to-cell interactions in the developing lung. Report of a conference held 3-5 June 1984.
Topics: Animals; Blood Vessels; Cell Communication; Cell Differentiation; Dihydrotestosterone; Endothelium; | 1984 |
Coronary neovascularization of embryonic rat hearts cultured in oculo is independent of thyroid hormones.
Topics: Animals; Antithyroid Agents; Coronary Vessels; Fetal Tissue Transplantation; Heart Transplantation; | 1995 |
Thyroxine-induced left ventricular hypertrophy in the rat. Anatomical and physiological evidence for angiogenesis.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Body Weight; Capillaries; Cardiomegaly; Coronary Circu | 1985 |