Page last updated: 2024-11-07

thyroxine and Anemia, Cooley's

thyroxine has been researched along with Anemia, Cooley's in 14 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone may induce hyper- or hypothyroidism."7.70High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment. ( Balestrieri, A; Lai, ME; Loviselli, A; Mandas, A; Mariotti, S; Martino, E; Murenu, S; Sau, F; Vacquer, S; Valentino, L, 1999)
" In 18 requiring thyroxine supplementation for hypothyroidism, 10 were able to discontinue, and four reduced their thyroxine dose."5.14Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major. ( Berdoukas, V; Chouliaras, G; Farmaki, K; Pappa, C; Tzoumari, I, 2010)
"Amiodarone may induce hyper- or hypothyroidism."3.70High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment. ( Balestrieri, A; Lai, ME; Loviselli, A; Mandas, A; Mariotti, S; Martino, E; Murenu, S; Sau, F; Vacquer, S; Valentino, L, 1999)
"Iron overload is a major problem in patients with b-thalassemia major, and it has many structural and metabolic consequences."1.38Effect of iron overload on endocrinopathies in patients with beta-thalassaemia major and intermedia. ( Kurtoglu, AU; Kurtoglu, E; Temizkan, AK, 2012)
" Our data demonstrate that GH treatment of thalassemic children with normal GH reserve and low serum IGF-I concentrations with supraphysiological doses of rhGH for one year can cause a significant increase in serum IGF-I levels and growth velocity, but it remains to be elucidated whether long-term administration will affect the final height."1.31Growth hormone treatment in short children with beta-thalassemia major. ( Athanasiou-Metaxa, M; Harsoulis, F; Katzos, G; Papakostantinou-Athanasiadou, E, 2000)
"Hypothyroidism was not present in our iron overloaded thalassaemic patients."1.30Thyroid function in thalassaemia major. ( Hubert, HD; Senanayake, MP; Suraweera, SA, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's7 (50.00)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Talibova, G1
Ozturk, Z1
Parlak, M1
Kupesiz, A1
De Sanctis, V3
Tanas, R1
Gamberini, MR2
Sprocati, M2
Govoni, MR2
Marsella, M2
De Sanctis, E1
Ricchieri, P1
Gubellini, E1
Gilli, G1
Conti, E1
Farmaki, K1
Tzoumari, I1
Pappa, C1
Chouliaras, G1
Berdoukas, V1
Kurtoglu, AU1
Kurtoglu, E1
Temizkan, AK1
Acquaviva, A1
Municchi, G1
Marconcini, S1
D'Ambrosio, A1
Morgese, G1
Jaruratanasirikul, S1
Wongcharnchailert, M1
Laosombat, V1
Sangsupavanich, P1
Leetanaporn, K1
Grundy, RG1
Woods, KA1
Savage, MO1
Evans, JP1
al-Hader, A1
Bashir, N1
Hasan, Z1
Khatib, S1
Mariotti, S1
Loviselli, A1
Murenu, S1
Sau, F1
Valentino, L1
Mandas, A1
Vacquer, S1
Martino, E1
Balestrieri, A1
Lai, ME1
Katzos, G1
Papakostantinou-Athanasiadou, E1
Athanasiou-Metaxa, M1
Harsoulis, F1
Senanayake, MP1
Suraweera, SA1
Hubert, HD1
Gulati, R1
Bhatia, V1
Agarwal, SS1

Trials

1 trial available for thyroxine and Anemia, Cooley's

ArticleYear
Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major.
    British journal of haematology, 2010, Volume: 148, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Blood Glucose; Cardiomyopathies; Child; Deferiprone; Deferoxami

2010

Other Studies

13 other studies available for thyroxine and Anemia, Cooley's

ArticleYear
Elevated Selenoprotein P Levels in Thalassemia Major Patients.
    Archives of medical research, 2022, Volume: 53, Issue:5

    Topics: beta-Thalassemia; Ferritins; Humans; P-Selectin; Selenium; Selenoprotein P; Thyrotropin; Thyroxine;

2022
Exaggerated TSH response to TRH ("sub-biochemical" hypothyroidism) in prepubertal and adolescent thalassaemic patients with iron overload: prevalence and 20-year natural history.
    Pediatric endocrinology reviews : PER, 2008, Volume: 6 Suppl 1

    Topics: Adolescent; beta-Thalassemia; Child; Humans; Hypothyroidism; Iron Overload; Retrospective Studies; S

2008
Mild subclinical hypothyroidism in thalassaemia major: prevalence, multigated radionuclide test, clinical and laboratory long-term follow-up study.
    Pediatric endocrinology reviews : PER, 2008, Volume: 6 Suppl 1

    Topics: Adolescent; Adult; beta-Thalassemia; Child; Female; Humans; Hypothyroidism; Iron Overload; Longitudi

2008
Cardiomyopathy and pericardial effusion in a 7 year-old boy with beta-thalassaemia major, severe primary hypothyroidism and hypoparathyroidism due to iron overload.
    Pediatric endocrinology reviews : PER, 2008, Volume: 6 Suppl 1

    Topics: beta-Thalassemia; Calcium; Cardiomyopathies; Cardiotonic Agents; Child; Digoxin; Diuretics; Humans;

2008
Effect of iron overload on endocrinopathies in patients with beta-thalassaemia major and intermedia.
    Endokrynologia Polska, 2012, Volume: 63, Issue:4

    Topics: Adolescent; Adult; beta-Thalassemia; Child; Endocrine System Diseases; Female; Ferritins; Glucose In

2012
Celiac disease in a patient with beta-thalassemia major.
    Journal of pediatric gastroenterology and nutrition, 2003, Volume: 36, Issue:4

    Topics: beta-Thalassemia; Blood Transfusion; Celiac Disease; Follow-Up Studies; Glutens; Hepatitis C; Humans

2003
Thyroid function in beta-thalassemic children receiving hypertransfusions with suboptimal iron-chelating therapy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2007, Volume: 90, Issue:9

    Topics: Adolescent; Age Factors; beta-Thalassemia; Blood Transfusion; Child; Cross-Sectional Studies; Female

2007
Relationship of endocrinopathy to iron chelation status in young patients with thalassaemia major.
    Archives of disease in childhood, 1994, Volume: 71, Issue:2

    Topics: Adolescent; beta-Thalassemia; Blood Transfusion; Child; Female; Glucagon; Growth; Growth Hormone; Hu

1994
Thyroid function in children with beta-thalassemia major in north Jordan.
    Journal of tropical pediatrics, 1993, Volume: 39, Issue:2

    Topics: beta-Thalassemia; Case-Control Studies; Child; Child, Preschool; Female; Humans; Jordan; Male; Thyro

1993
High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:1

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; beta-Thalassemia; Female; Humans; Hypothyroidism; Male; T

1999
Growth hormone treatment in short children with beta-thalassemia major.
    Journal of pediatric endocrinology & metabolism : JPEM, 2000, Volume: 13, Issue:2

    Topics: beta-Thalassemia; Body Height; Child; Growth Disorders; Growth Hormone; Humans; Insulin; Insulin-Lik

2000
Thyroid function in thalassaemia major.
    The Ceylon medical journal, 1999, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Age Determination by Skeleton; beta-Thalassemia; Body Height; Child; Child, Presc

1999
Early onset of endocrine abnormalities in beta-thalassemia major in a developing country.
    Journal of pediatric endocrinology & metabolism : JPEM, 2000, Volume: 13, Issue:6

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; beta-Thalassemia; Body Height; Child; Child, Prescho

2000