Page last updated: 2024-11-06

thyroxine and Alkaptonuria

thyroxine has been researched along with Alkaptonuria in 2 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Alkaptonuria: An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.

Research Excerpts

ExcerptRelevanceReference
"Alkaptonuria is an autosomal recessive disorder caused by pathogenic variants in the HGD gene."1.56Assessment of Thyroid Function in Patients With Alkaptonuria. ( Auh, S; Avadhanula, S; Burman, KD; Ciccone, C; Filie, AC; Hannah-Shmouni, F; Introne, WJ; Klubo-Gwiezdzinska, J; Regier, D; Soldin, SJ; Stolze, B, 2020)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Avadhanula, S1
Introne, WJ1
Auh, S1
Soldin, SJ1
Stolze, B1
Regier, D1
Ciccone, C1
Hannah-Shmouni, F1
Filie, AC1
Burman, KD1
Klubo-Gwiezdzinska, J1
Rosenberg, EF1
Blivaiss, BB1

Other Studies

2 other studies available for thyroxine and Alkaptonuria

ArticleYear
Assessment of Thyroid Function in Patients With Alkaptonuria.
    JAMA network open, 2020, 03-02, Volume: 3, Issue:3

    Topics: Adult; Alkaptonuria; Autoantibodies; Autoantigens; Cohort Studies; Female; Homogentisic Acid; Humans

2020
[Alkaptonuria and osteoarthritis. An experimental reproduction of primary human osteoarthritis].
    Prensa medica argentina, 1966, Volume: 53, Issue:9

    Topics: Alkaptonuria; Animals; Culture Media; Osteoarthritis; Rats; Thyroxine

1966