thyroxine has been researched along with Alcohol Related Neurodevelopmental Disorder in 13 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Expression of autism candidates, Gabrb3, Ube3a, Mecp2, and Slc25a12, was significantly increased in the hippocampus of male offspring of EtOH dams." | 5.39 | Low-dose thyroxine attenuates autism-associated adverse effects of fetal alcohol in male offspring's social behavior and hippocampal gene expression. ( Redei, EE; Shukla, PK; Tunc-Ozcan, E; Ullmann, TM, 2013) |
| "This study examines the effect of women's alcohol abuse during pregnancy on the thyroid-stimulating hormone (TSH) and thyroxine (T4) levels of their babies at birth." | 3.68 | The effect of drug exposure on thyroid hormone levels of newborns. ( Cvejin, S; Hernandez, JT; Hoffman, L; Prange, AJ; Weavil, S, 1992) |
| "Hippocampus-based learning and memory deficits are key symptoms of FASD." | 1.48 | Hippocampus-dependent memory and allele-specific gene expression in adult offspring of alcohol-consuming dams after neonatal treatment with thyroxin or metformin. ( Ferreira, A; Lim, PH; Redei, EE; Tunc-Ozcan, E; Wert, SL, 2018) |
| "The neurodevelopmental fetal alcohol spectrum disorder (FASD) is characterized by cognitive and behavioral deficits in the offspring." | 1.43 | Thyroxine administration prevents matrilineal intergenerational consequences of in utero ethanol exposure in rats. ( Graf, EN; Harper, KM; Redei, EE; Tunc-Ozcan, E, 2016) |
| "Expression of autism candidates, Gabrb3, Ube3a, Mecp2, and Slc25a12, was significantly increased in the hippocampus of male offspring of EtOH dams." | 1.39 | Low-dose thyroxine attenuates autism-associated adverse effects of fetal alcohol in male offspring's social behavior and hippocampal gene expression. ( Redei, EE; Shukla, PK; Tunc-Ozcan, E; Ullmann, TM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tunc-Ozcan, E | 4 |
| Wert, SL | 1 |
| Lim, PH | 1 |
| Ferreira, A | 1 |
| Redei, EE | 6 |
| Ullmann, TM | 1 |
| Shukla, PK | 1 |
| Harper, KM | 2 |
| Graf, EN | 2 |
| Wilcoxon, JS | 2 |
| Kuo, AG | 1 |
| Disterhoft, JF | 1 |
| Ramadoss, J | 1 |
| Tress, U | 1 |
| Chen, WJ | 1 |
| Cudd, TA | 1 |
| Hannigan, JH | 2 |
| Martier, SS | 1 |
| Naber, JM | 1 |
| Nathaniel, EJ | 1 |
| Hassard, T | 1 |
| Burton, L | 1 |
| Novak, C | 1 |
| Kornguth, SE | 1 |
| Rutledge, JJ | 1 |
| Sunderland, E | 1 |
| Siegel, F | 1 |
| Carlson, I | 1 |
| Smollens, J | 1 |
| Juhl, U | 1 |
| Young, B | 1 |
| Hernandez, JT | 1 |
| Hoffman, L | 1 |
| Weavil, S | 1 |
| Cvejin, S | 1 |
| Prange, AJ | 1 |
| Gottesfeld, Z | 1 |
| Silverman, PB | 1 |
| Bellisario, RL | 1 |
13 other studies available for thyroxine and Alcohol Related Neurodevelopmental Disorder
| Article | Year |
|---|---|
Hippocampus-dependent memory and allele-specific gene expression in adult offspring of alcohol-consuming dams after neonatal treatment with thyroxin or metformin.
Topics: Alcohol Drinking; Alleles; Animals; Ethanol; Fear; Female; Fetal Alcohol Spectrum Disorders; Hippoca | 2018 |
Low-dose thyroxine attenuates autism-associated adverse effects of fetal alcohol in male offspring's social behavior and hippocampal gene expression.
Topics: Animals; Autistic Disorder; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Male; Pr | 2013 |
Intergenerational effects of prenatal ethanol on glucose tolerance and insulin response.
Topics: Animals; Blood Glucose; Body Weight; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glucose Tole | 2014 |
Thyroxine administration prevents matrilineal intergenerational consequences of in utero ethanol exposure in rats.
Topics: Alcohol Drinking; Animals; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Hypothyro | 2016 |
Prenatal programming of adult thyroid function by alcohol and thyroid hormones.
Topics: Adaptation, Physiological; Age Factors; Analysis of Variance; Animals; Corticosterone; Ethanol; Fema | 2004 |
Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE.
Topics: Animals; Female; Fetal Alcohol Spectrum Disorders; GAP-43 Protein; Hippocampus; Mental Disorders; Po | 2005 |
Maternal adrenocorticotropin, cortisol, and thyroid hormone responses to all three-trimester equivalent repeated binge alcohol exposure: ovine model.
Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Animals; Central Nervous System Depressants; Data Int | 2008 |
Independent associations among maternal alcohol consumption and infant thyroxine levels and pregnancy outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Black People; Child; Female; Fetal Alcohol Spectrum Disorders; | 1995 |
Effect of exogenous thyroxine on the development of the Purkinje cell in fetal alcohol effects in the rat.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spect | 1999 |
Impeded cerebellar development and reduced serum thyroxine levels associated with fetal alcohol intoxication.
Topics: Alcohol Drinking; Animals; Aspartate Aminotransferases; Body Weight; Cerebellar Cortex; Cerebral Cor | 1979 |
The effect of drug exposure on thyroid hormone levels of newborns.
Topics: Alcoholism; Cocaine; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Male; Mariju | 1992 |
Developmental delays associated with prenatal alcohol exposure are reversed by thyroid hormone treatment.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Disease Models, Animal; Embryonic and Fetal | 1990 |
Lower serum thyroxine levels in rats following prenatal exposure to ethanol.
Topics: Alcohol Drinking; Animals; Animals, Newborn; Body Weight; Female; Fetal Alcohol Spectrum Disorders; | 1990 |