Page last updated: 2024-11-06

thyroxine and Alcohol Abuse

thyroxine has been researched along with Alcohol Abuse in 44 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"This study examines the effect of women's alcohol abuse during pregnancy on the thyroid-stimulating hormone (TSH) and thyroxine (T4) levels of their babies at birth."3.68The effect of drug exposure on thyroid hormone levels of newborns. ( Cvejin, S; Hernandez, JT; Hoffman, L; Prange, AJ; Weavil, S, 1992)
"Vitamin D deficiency was defined as serum concentrations of the main circulating vitamin D, 25-hydroxy vitamin D [25(OH)D], below 50 nmol/L."1.91Relationship between serum vitamin D and thyroid hormone profiles in male patients with alcohol dependence. ( Liu, Y; Pang, L; Wang, Y; Xu, Y; Zhang, X, 2023)
"After 4-wk of treatment, the body weight of the ethanol group was 7% and of the pair-fed rats 19% lower than that of the absolute controls."1.30Chronic ethanol drinking and food deprivation affect rat hypothalamic-pituitary-thyroid axis and TRH in septum. ( Benický, J; Brtko, J; Nikodémová, M; Strbák, V, 1998)
" These results suggest that chronic administration of ethanol affects intracellular thyroid hormone metabolism in both rat CNS and liver in the highly complex manner."1.29Hypothalamic-pituitary-thyroid axis in chronic alcoholism. II. Deiodinase activities and thyroid hormone concentrations in brain and peripheral tissues of rats chronically exposed to ethanol. ( Baumgartner, A; Campos-Barros, A; Heyne, A; Köhler, R; Meinhold, H; Müller, F; Rommelspacher, H; Wolffgramm, J, 1994)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199022 (50.00)18.7374
1990's15 (34.09)18.2507
2000's2 (4.55)29.6817
2010's3 (6.82)24.3611
2020's2 (4.55)2.80

Authors

AuthorsStudies
Liu, Y1
Xu, Y1
Wang, Y1
Pang, L1
Zhang, X1
Vetlugina, TP1
Lobacheva, OA1
Nikitina, VB1
Prokopieva, VD1
Mandel, AI1
Bokhan, NA1
Díaz-Fontenla, F1
Castillo-Pradillo, M1
Díaz-Gómez, A1
Ibañez-Samaniego, L1
Gancedo, P1
Guzmán-de-Villoria, JA1
Fernández-García, P1
Bañares-Cañizares, R1
García-Martínez, R1
Shimizu, Y1
Nakazato, M1
Sekita, T1
Kadota, K1
Arima, K1
Yamasaki, H1
Goto, H1
Takamura, N1
Aoyagi, K1
Maeda, T1
Sinai, C1
Hirvikoski, T1
Nordström, AL1
Nordström, P1
Nilsonne, Å1
Wilczek, A1
Åsberg, M1
Jokinen, J1
Hermann, D1
Heinz, A1
Mann, K1
Rasmussen, DD1
Loosen, PT4
Wilson, IC1
Dew, BW2
Tipermas, A1
Dackis, CA1
Bailey, J1
Pottash, AL1
Stuckey, RF1
Extein, IL1
Gold, MS1
Prange, AJ3
Geurts, J1
Demeester-Mirkine, N1
Glinoer, D1
Prigogine, T1
Fernandez-Deville, M1
Corvilain, J1
Melander, A1
Thorell, J1
Wadstein, J1
Majumdar, SK1
Shaw, GK1
Thomson, AD1
Sudha, S1
Balasubramanian, K1
Arunakaran, J1
Govindarajulu, P1
Baumgartner, A2
Heyne, A1
Campos-Barros, A1
Köhler, R1
Müller, F1
Meinhold, H2
Rommelspacher, H1
Wolffgramm, J1
Garbutt, JC1
Miller, LP1
Karnitschnig, JS1
Mason, GA1
Jimenez, J1
Osuna, C1
Rubio, A1
Guerrero, JM1
Pienaar, WP1
Roberts, MC1
Emsley, RA1
Aalbers, C1
Taljaard, FJ1
Kaptein, EM2
Eravci, M1
Pinna, G1
Hiedra, L1
Prengel, H1
Brödel, O1
Shibagaki, K1
Yonei, Y1
Nagamori, N1
Tsukada, N1
Inagaki, Y1
Miyamoto, K1
Nakazawa, A1
Suzuki, O1
Kawamura, Y1
Kiryu, T1
Nikodémová, M1
Benický, J1
Brtko, J1
Strbák, V1
van Thiel, DH1
Lester, R1
Dobrzański, T1
Pieschl, D1
Singh, SP1
Snyder, AK1
Bleich, HL1
Boro, ES1
Kolakowska, T1
Swigar, ME1
Israel, Y2
Videla, L2
Bernstein, J2
Nomura, S1
Pittman, CS1
Chambers, JB1
Buck, MW1
Shimizu, T1
Anderson, DL1
Nelson, JC1
Haviland, MG1
MacMurray, JP1
Cummings, MA1
McGhee, WH1
Hubbard, RW1
Hernandez, JT1
Hoffman, L1
Weavil, S1
Cvejin, S1
Adinoff, B1
Nemeroff, CB1
Bissette, G1
Martin, PR1
Linnoila, M1
Willenbring, ML1
Anton, RF1
Spring, WD1
Shafer, RB1
Dorus, W1
Knudsen, GM1
Christensen, H1
Berild, D1
Melgaard, B1
Kirkegaard, C1
Hasselbalch, H1
Grimaldi, F1
De Marchi, S1
Cecchin, E1
Marciniak, R1
Thadani, K1
Kaptein, JS1
Chang, EI1
Egodage, PM1
Nicoloff, JT1
Massry, SG1
Borodulin, VG1
Avdienko, VN1
Tolkaeva, MV1
Nordkild, P1
Kromann-Andersen, H1
Pamenter, RW1
Boyden, TW1
Agostoni, A1
Vergani, C1
Stabilini, R1
Petrella, A1
Chopra, IJ1
Solomon, DH1
Chopra, U1
Young, RT1
Chua Teco, GN1

Reviews

3 reviews available for thyroxine and Alcohol Abuse

ArticleYear
Dysregulation of the hypothalamic-pituitary-thyroid axis in alcoholism.
    Addiction (Abingdon, England), 2002, Volume: 97, Issue:11

    Topics: Alcoholism; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Substance Withdrawal Syndrome; T

2002
Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications.
    Federation proceedings, 1975, Volume: 34, Issue:11

    Topics: Alcoholism; Animals; Biological Transport; Catecholamines; Cytosol; Dinitrophenols; Dose-Response Re

1975
Role of the sodium pump in the regulation of liver metabolism in experimental alcoholism.
    Annals of the New York Academy of Sciences, 1974, Volume: 242, Issue:0

    Topics: Adenosine Triphosphatases; Alcoholism; Animals; Biological Transport, Active; Dinitrophenols; Enzyme

1974

Trials

1 trial available for thyroxine and Alcohol Abuse

ArticleYear
Preliminary study of androgen, thyroid & adrenal status in alcoholic men during deaddiction.
    The Indian journal of medical research, 1995, Volume: 101

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex; Adult; Alcoholism; Estradiol; Estrone; H

1995

Other Studies

40 other studies available for thyroxine and Alcohol Abuse

ArticleYear
Relationship between serum vitamin D and thyroid hormone profiles in male patients with alcohol dependence.
    BMC psychiatry, 2023, 10-24, Volume: 23, Issue:1

    Topics: Alcoholism; Humans; Male; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Vitamin D; Vit

2023
[Hormones of stress-response system in alcohol dependence: the ability to predict duration of remission].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2020, Volume: 120, Issue:5

    Topics: Alcoholism; Humans; Male; Thyroid Hormones; Thyrotropin; Thyroxine

2020
Refractory hepatic encephalopathy in a patient with hypothyroidism: Another element in ammonia metabolism.
    World journal of gastroenterology, 2017, Jul-28, Volume: 23, Issue:28

    Topics: Adrenergic beta-Antagonists; Alcoholism; Ammonia; Antithyroid Agents; Brain; Carbimazole; Diagnosis,

2017
Free thyroxine (FT4) and anemia in relation to drinking status of Japanese men: the Nagasaki islands study.
    Endocrine journal, 2013, Volume: 60, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Alcoholism; Anemia, Hypochromic; Cardiovascular Di

2013
Thyroid hormones and adult interpersonal violence among women with borderline personality disorder.
    Psychiatry research, 2015, Jun-30, Volume: 227, Issue:2-3

    Topics: Adult; Aggression; Alcoholism; Biomarkers; Borderline Personality Disorder; Case-Control Studies; Fe

2015
Chronic daily ethanol and withdrawal: 5. Diurnal effects on plasma thyroid hormone levels.
    Endocrine, 2003, Volume: 22, Issue:3

    Topics: Alcoholism; Animals; Circadian Rhythm; Ethanol; Male; Rats; Rats, Sprague-Dawley; Substance Withdraw

2003
Thyrotropin-releasing hormone (TRH) in abstinent alcoholic men.
    The American journal of psychiatry, 1983, Volume: 140, Issue:9

    Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Depressive Disorder; Growth Hormone; Humans; Male; Middle

1983
Specificity of the DST and the TRH test for major depression in alcoholics.
    The American journal of psychiatry, 1984, Volume: 141, Issue:5

    Topics: Adult; Alcoholism; Depressive Disorder; Dexamethasone; Ethanol; Female; Humans; Hydrocortisone; Male

1984
Thyrotropin releasing hormone (TRH): a useful tool for psychoneuroendocrine investigation.
    Psychoneuroendocrinology, 1980, Volume: 5, Issue:1

    Topics: Adult; Alcoholism; Depression; Endocrine Glands; Female; Growth Hormone; Humans; Male; Middle Aged;

1980
Alterations in circulating thyroid hormones and thyroxine binding globulin in chronic alcoholism.
    Clinical endocrinology, 1981, Volume: 14, Issue:2

    Topics: Adult; Alcoholism; Female; Humans; Male; Middle Aged; Thyroid Function Tests; Thyroxine; Thyroxine-B

1981
Alteration of thyroid hormone economy during alcohol withdrawal in alcoholics.
    Drug-nutrient interactions, 1982, Volume: 1, Issue:2

    Topics: Alcohol Withdrawal Delirium; Alcoholism; Humans; Substance Withdrawal Syndrome; Thyroid Hormones; Th

1982
Thyroid status in chronic alcoholics.
    Drug and alcohol dependence, 1981, Volume: 7, Issue:1

    Topics: Adult; Alcoholism; Female; Humans; Male; Middle Aged; Thyroid Gland; Thyrotropin; Thyroxine; Triiodo

1981
Hypothalamic-pituitary-thyroid axis in chronic alcoholism. II. Deiodinase activities and thyroid hormone concentrations in brain and peripheral tissues of rats chronically exposed to ethanol.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:2

    Topics: Alcoholism; Animals; Brain; Hypothalamo-Hypophyseal System; Iodide Peroxidase; Isoenzymes; Male; Rat

1994
Thyrotropin response to thyrotropin-releasing hormone in young men at high or low risk for alcoholism.
    Annals of the New York Academy of Sciences, 1994, Feb-28, Volume: 708

    Topics: Adult; Alcohol Drinking; Alcoholism; Cocaine; Humans; Hydrocortisone; Male; Marijuana Abuse; Prolact

1994
Effect of chronic ethanol administration on the rat pineal N-acetyltransferase and thyroxine type II 5'-deiodinase activities.
    Bioscience reports, 1993, Volume: 13, Issue:2

    Topics: Alcoholism; Animals; Arylamine N-Acetyltransferase; Body Weight; Circadian Rhythm; Ethanol; Iodide P

1993
The thyrotropin releasing hormone stimulation test in alcoholism.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1995, Volume: 30, Issue:5

    Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Female; Gonadotropin-Releasing Hormone; Humans; Hydr

1995
Hormone-specific alterations of T4, T3, and reverse T3 metabolism with recent ethanol abstinence in humans.
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Adult; Alcoholism; Ethanol; Female; Humans; Male; Middle Aged; Models, Biological; Reference Values;

1997
Thyroid hormone metabolism in the rat brain in an animal model of 'behavioral dependence' on ethanol.
    Neuroscience letters, 1997, May-09, Volume: 227, Issue:1

    Topics: Alcoholism; Amygdala; Animals; Behavior, Animal; Catalysis; Disease Models, Animal; Frontal Lobe; Io

1997
[Case of intestinal pseudo-obstruction associated with hypothyroidism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1998, Jan-10, Volume: 87, Issue:1

    Topics: Alcoholism; Female; Humans; Hypothyroidism; Intestinal Pseudo-Obstruction; Middle Aged; Thyroxine

1998
Chronic ethanol drinking and food deprivation affect rat hypothalamic-pituitary-thyroid axis and TRH in septum.
    Endocrine, 1998, Volume: 9, Issue:2

    Topics: Alcoholism; Animals; Body Weight; Ethanol; Food Deprivation; Hypothalamus; Iodide Peroxidase; Liver;

1998
Further evidence for hypothalamic-pituitary dysfunction in alcoholic men.
    Alcoholism, clinical and experimental research, 1978, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Alcoholism; Gonadotropin-Releasing Hormone; Humans; Hypothalamo-Hypophyseal Syste

1978
[Plasma ACTH, STH and other hormone levels in various groups under chlormethiazole, haloperidol or reserpine load in alchohol delirium, alcoholic hallucinations, and chronic alcoholism].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Alcohol Withdrawal Delirium; Alcoholism; Blo

1976
Interaction of ethanol and thyroxine on hepatic oxygen consumption.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 159, Issue:2

    Topics: Alcoholism; Animals; Drug Synergism; Ethanol; Humans; Hyperthyroidism; In Vitro Techniques; Liver; M

1978
Metabolic and hepatic effects of alcohol.
    The New England journal of medicine, 1977, Mar-17, Volume: 296, Issue:11

    Topics: Acidosis; Alcohol Oxidoreductases; Alcoholism; Amino Acids; Animals; Carbohydrate Metabolism; Chemic

1977
Thyroid function in depression and alcohol abuse: a retrospective study.
    Archives of general psychiatry, 1977, Volume: 34, Issue:8

    Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Alcoholism; Antidepressive

1977
Reduced peripheral conversion of thyroxine to triiodothyronine in patients with hepatic cirrhosis.
    The Journal of clinical investigation, 1975, Volume: 56, Issue:3

    Topics: Adult; Aged; Alcoholism; Humans; Kinetics; Liver; Liver Cirrhosis; Liver Function Tests; Male; Metab

1975
Thyroid stimulating hormone and prolactin responses to thyrotropin releasing hormone in nondepressed alcoholic inpatients.
    Psychiatry research, 1992, Volume: 43, Issue:2

    Topics: Adult; Alcoholism; Humans; Male; Prolactin; Regression Analysis; Substance Abuse Treatment Centers;

1992
The effect of drug exposure on thyroid hormone levels of newborns.
    Biochemical medicine and metabolic biology, 1992, Volume: 48, Issue:3

    Topics: Alcoholism; Cocaine; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Male; Mariju

1992
Inverse relationship between CSF TRH concentrations and the TSH response to TRH in abstinent alcohol-dependent patients.
    The American journal of psychiatry, 1991, Volume: 148, Issue:11

    Topics: Adult; Alcoholism; Down-Regulation; Humans; Male; Middle Aged; Pituitary Gland, Anterior; Receptors,

1991
Thyrotropin and prolactin response to thyrotropin-releasing hormone in depressed and nondepressed alcoholic men.
    Biological psychiatry, 1990, Jan-01, Volume: 27, Issue:1

    Topics: Adult; Alcoholism; Depressive Disorder; Humans; Male; Middle Aged; Personality Tests; Prolactin; Thy

1990
Long-term predictors of outcome in abstinent alcoholic men.
    The American journal of psychiatry, 1990, Volume: 147, Issue:12

    Topics: Adult; Aged; Alcoholism; Comorbidity; Depressive Disorder; Follow-Up Studies; Growth Hormone; Humans

1990
Hypothalamic-pituitary and thyroid function in chronic alcoholics with neurological complications.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Alcoholism; Blood Glucose; Gonadotropin-Releasing Hormone; Growth

1990
[Low T4 syndrome in alcoholism: role of the decrease in TBG].
    Minerva medica, 1986, Mar-17, Volume: 77, Issue:11

    Topics: Adult; Aged; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Erythrocyte Volume; Fema

1986
TRH-induced TSH response in healthy volunteers: relationship to psychiatric history.
    The American journal of psychiatry, 1987, Volume: 144, Issue:4

    Topics: Adult; Alcoholism; Depressive Disorder; Female; Humans; Male; Sex Factors; Thyrotropin; Thyrotropin-

1987
Thyroxine transfer and distribution in critical nonthyroidal illnesses, chronic renal failure, and chronic ethanol abuse.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 65, Issue:4

    Topics: Acute Disease; Alcoholism; Euthyroid Sick Syndromes; Female; Humans; Kidney Failure, Chronic; Male;

1987
[Hypophyseal-thyroid system in chronic alcoholism].
    Meditsinskaia radiologiia, 1986, Volume: 31, Issue:10

    Topics: Adult; Alcoholism; Female; Humans; Iodine Radioisotopes; Liver; Male; Middle Aged; Pituitary Gland;

1986
[Transient hypothyroxinemia in a beer-drinker with hyponatremia].
    Ugeskrift for laeger, 1985, Mar-11, Volume: 147, Issue:11

    Topics: Aged; Alcoholism; Beer; Humans; Hyponatremia; Male; Thyroxine; Triiodothyronine

1985
One year of ethanol feeding increases circulating thyroid hormones in the dog.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:2

    Topics: Alcoholism; Analysis of Variance; Animals; Blood Proteins; Dogs; Humans; Liver Diseases, Alcoholic;

1985
Thyroxine-binding prealbumin in alcoholic cirrhosis.
    Lancet (London, England), 1968, Apr-27, Volume: 1, Issue:7548

    Topics: Alcoholism; Blood Proteins; Humans; Iodine; Liver Cirrhosis; Protein Binding; Serum Albumin; Thyroxi

1968
Alterations in circulating thyroid hormones and thyrotropin in hepatic cirrhosis: evidence for euthyroidism despite subnormal serum triiodothyronine.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:3

    Topics: Achilles Tendon; Adult; Aged; Alcoholism; Blood; Female; Humans; Infant, Newborn; Injections, Intrav

1974