Page last updated: 2024-11-06

thyroxine and Alactasia

thyroxine has been researched along with Alactasia in 8 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"The preferred treatment for hypothyroidism is oral levothyroxine (LT4) ingestion, in doses that ensure a sustained state of hormonal balance."8.88The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption. ( Ruchała, M; Szczepanek-Parulska, E; Zybek, A, 2012)
"We describe a case of a 38-year-old woman who, after radioactive iodine therapy for Graves' disease, developed severe hypothyroidism despite receiving a high dose of levothyroxine (L-T4) tablet as replacement therapy."8.12Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance. ( Aso, Y; Iijima, T; Jojima, T; Kogai, T; Ohira, E; Sakurai, S; Shinzawa, T; Tomaru, T; Usui, I, 2022)
"Purpose: to determine lactose intolerance (LI) prevalence in women with Hashimoto’s thyroiditis (HT) and assess the impact of LI on LT4 replacement dose."8.12Prevalence of Lactose Intolerance in Patients with Hashimoto Thyroiditis and Impact on LT4 Replacement Dose. ( Albertelli, M; Bagnasco, M; Bodini, G; Ferone, D; Furnari, M; Giannini, EG; Giusti, M; Marabotto, E; Navarro Rojas, FA; Savarino, E; Savarino, V; Sheijani, AD; Vera, L; Zentilin, P; Ziola, S, 2022)
" However, an abnormality in the bioavailability of LT(4) should also be considered in patients requiring large doses of LT(4) to achieve euthyroidism."5.33Lactose intolerance revealed by severe resistance to treatment with levothyroxine. ( Alonso, G; Muñoz-Torres, M; Varsavsky, M, 2006)
"The preferred treatment for hypothyroidism is oral levothyroxine (LT4) ingestion, in doses that ensure a sustained state of hormonal balance."4.88The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption. ( Ruchała, M; Szczepanek-Parulska, E; Zybek, A, 2012)
"We describe a case of a 38-year-old woman who, after radioactive iodine therapy for Graves' disease, developed severe hypothyroidism despite receiving a high dose of levothyroxine (L-T4) tablet as replacement therapy."4.12Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance. ( Aso, Y; Iijima, T; Jojima, T; Kogai, T; Ohira, E; Sakurai, S; Shinzawa, T; Tomaru, T; Usui, I, 2022)
"Purpose: to determine lactose intolerance (LI) prevalence in women with Hashimoto’s thyroiditis (HT) and assess the impact of LI on LT4 replacement dose."4.12Prevalence of Lactose Intolerance in Patients with Hashimoto Thyroiditis and Impact on LT4 Replacement Dose. ( Albertelli, M; Bagnasco, M; Bodini, G; Ferone, D; Furnari, M; Giannini, EG; Giusti, M; Marabotto, E; Navarro Rojas, FA; Savarino, E; Savarino, V; Sheijani, AD; Vera, L; Zentilin, P; Ziola, S, 2022)
" However, an abnormality in the bioavailability of LT(4) should also be considered in patients requiring large doses of LT(4) to achieve euthyroidism."1.33Lactose intolerance revealed by severe resistance to treatment with levothyroxine. ( Alonso, G; Muñoz-Torres, M; Varsavsky, M, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Jojima, T1
Shinzawa, T1
Ohira, E1
Sakurai, S1
Tomaru, T1
Iijima, T1
Kogai, T1
Usui, I1
Aso, Y1
Marabotto, E1
Ferone, D1
Sheijani, AD1
Vera, L1
Ziola, S1
Savarino, E1
Bodini, G1
Furnari, M1
Zentilin, P1
Savarino, V1
Giusti, M1
Navarro Rojas, FA1
Bagnasco, M1
Albertelli, M1
Giannini, EG1
Cellini, M1
Santaguida, MG1
Gatto, I1
Virili, C1
Del Duca, SC1
Brusca, N1
Capriello, S1
Gargano, L1
Centanni, M1
Fallahi, P1
Ferrari, SM1
Marchi, S1
De Bortoli, N1
Ruffilli, I1
Antonelli, A1
Liwanpo, L1
Hershman, JM1
Fruzza, AG1
Demeterco-Berggren, C1
Jones, KL1
Ruchała, M1
Szczepanek-Parulska, E1
Zybek, A1
Muñoz-Torres, M1
Varsavsky, M1
Alonso, G1

Reviews

2 reviews available for thyroxine and Alactasia

ArticleYear
Conditions and drugs interfering with thyroxine absorption.
    Best practice & research. Clinical endocrinology & metabolism, 2009, Volume: 23, Issue:6

    Topics: Aluminum Hydroxide; Animals; Antacids; Biological Availability; Calcium Carbonate; Celiac Disease; C

2009
The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption.
    Endokrynologia Polska, 2012, Volume: 63, Issue:4

    Topics: Celiac Disease; Diet, Gluten-Free; Dose-Response Relationship, Drug; Drug Resistance; Gastrointestin

2012

Trials

1 trial available for thyroxine and Alactasia

ArticleYear
Systematic appraisal of lactose intolerance as cause of increased need for oral thyroxine.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Cohort Studies; Diet, Carbohydrate-Restricted; Dose-Respons

2014

Other Studies

5 other studies available for thyroxine and Alactasia

ArticleYear
Switching from the tablet to the powder formulation of levothyroxine corrects severe hypothyroidism in a patient with lactose intolerance.
    Endocrine journal, 2022, Aug-29, Volume: 69, Issue:8

    Topics: Adult; Female; Humans; Hypothyroidism; Iodine Radioisotopes; Lactose Intolerance; Powders; Tablets;

2022
Prevalence of Lactose Intolerance in Patients with Hashimoto Thyroiditis and Impact on LT4 Replacement Dose.
    Nutrients, 2022, Jul-22, Volume: 14, Issue:15

    Topics: Adult; Aged; Female; Gastrointestinal Diseases; Hashimoto Disease; Humans; Lactose; Lactose Intolera

2022
Patients with lactose intolerance absorb liquid levothyroxine better than tablet levothyroxine.
    Endocrine, 2017, Volume: 57, Issue:1

    Topics: Adult; Drug Compounding; Female; Hashimoto Disease; Hormone Replacement Therapy; Humans; Hypothyroid

2017
Unawareness of the effects of soy intake on the management of congenital hypothyroidism.
    Pediatrics, 2012, Volume: 130, Issue:3

    Topics: Child, Preschool; Congenital Hypothyroidism; Female; Food-Drug Interactions; Humans; Infant, Newborn

2012
Lactose intolerance revealed by severe resistance to treatment with levothyroxine.
    Thyroid : official journal of the American Thyroid Association, 2006, Volume: 16, Issue:11

    Topics: Drug Resistance; Female; Humans; Hypothyroidism; Intestinal Absorption; Lactose Intolerance; Middle

2006