thyroxine has been researched along with Agranulocytosis in 8 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Possible adverse effects of this therapy include cardiovascular changes (shortening of systolic time intervals, increased frequency of atrial premature beats and, possibly, left ventricular hypertrophy) and bone changes (reduced bone density and bone mass), but the risk of these adverse effects can be minimised by carefully monitoring serum free thyroxine and free liothyronine (triiodothyronine) measurements and adjusting the dosage accordingly." | 2.39 | Adverse effects of thyroid hormone preparations and antithyroid drugs. ( Bartalena, L; Bogazzi, F; Martino, E, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tong, J | 1 |
| Fu, YS | 1 |
| Hao, HJ | 1 |
| Guo, TL | 1 |
| Han, D | 1 |
| Wang, Q | 1 |
| Gao, YM | 1 |
| Wen, HX | 1 |
| Guo, HN | 1 |
| Ezer, A | 1 |
| Caliskan, K | 1 |
| Parlakgumus, A | 1 |
| Belli, S | 1 |
| Kozanoglu, I | 1 |
| Yildirim, S | 1 |
| DAFT, FS | 1 |
| KORNBERG, A | 1 |
| Cooper, DS | 1 |
| Bartalena, L | 1 |
| Bogazzi, F | 1 |
| Martino, E | 1 |
| Tamagna, EI | 1 |
| Carlson, HE | 1 |
| Hershman, JM | 1 |
| Reed, AW | 1 |
| Lothrop, CD | 1 |
| Coulson, PA | 1 |
| Nolan, HL | 1 |
| Cole, B | 1 |
| Jones, JB | 1 |
| Sanders, WL | 1 |
| Wahlberg, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Evaluation of High Intensity Focused Ultrasound (HIFU) in the Treatment of Relapsed Graves' Disease[NCT02685514] | 22 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thyroxine and Agranulocytosis
| Article | Year |
|---|---|
Antithyroid drugs.
Topics: Agranulocytosis; Algorithms; Antithyroid Agents; Female; Graves Disease; Humans; Hyperthyroidism; Me | 2005 |
Adverse effects of thyroid hormone preparations and antithyroid drugs.
Topics: Adult; Agranulocytosis; Antithyroid Agents; Bone and Bones; Carbimazole; Cardiovascular System; Chil | 1996 |
[Long-term treatment of thyrotoxicosis with antithyroid drugs].
Topics: Agranulocytosis; Antithyroid Agents; Carbimazole; Eye Manifestations; Female; Follow-Up Studies; Goi | 1970 |
5 other studies available for thyroxine and Agranulocytosis
| Article | Year |
|---|---|
[Changes of granulocyte distribution induced by thyroxin and epinephrine: experiment with rabbits].
Topics: Agranulocytosis; Animals; Epinephrine; Female; Leukocyte Count; Leukocytes; Male; Rabbits; Thyrotoxi | 2008 |
Preoperative therapeutic plasma exchange in patients with thyrotoxicosis.
Topics: Adult; Agranulocytosis; Antithyroid Agents; Female; Humans; Male; Middle Aged; Plasma Exchange; Preo | 2009 |
Granulocytopenia in rats given thiourea and thyroxin; the therapeutic effect of L. casei factor.
Topics: Agranulocytosis; Animals; Rats; Thiourea; Thyroxine | 1946 |
Pituitary and peripheral resistance to thyroid hormone.
Topics: Adult; Agranulocytosis; Humans; Hyperthyroidism; Iodine; Male; Metabolic Clearance Rate; Pituitary G | 1979 |
Cyclic hormonogenesis in gray collie dogs: interactions of hematopoietic and endocrine systems.
Topics: Adrenocorticotropic Hormone; Agranulocytosis; Animals; Disease Models, Animal; Dogs; Endocrine Gland | 1987 |