thyroxine has been researched along with Adrenal Cortex Cancer in 3 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitotane-treated patients with ACC showed low FT4, normal FT3 and TSH and impaired TSH response to TRH, characteristic of central hypothyroidism." | 7.83 | Mitotane treatment in patients with adrenocortical cancer causes central hypothyroidism. ( Cannavò, S; Cotta, OR; Frasca, F; Gullo, D; Pellegriti, G; Russo, M; Scollo, C; Squatrito, S, 2016) |
| "Mitotane-treated patients with ACC showed low FT4, normal FT3 and TSH and impaired TSH response to TRH, characteristic of central hypothyroidism." | 3.83 | Mitotane treatment in patients with adrenocortical cancer causes central hypothyroidism. ( Cannavò, S; Cotta, OR; Frasca, F; Gullo, D; Pellegriti, G; Russo, M; Scollo, C; Squatrito, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, M | 1 |
| Scollo, C | 1 |
| Pellegriti, G | 1 |
| Cotta, OR | 1 |
| Squatrito, S | 1 |
| Frasca, F | 1 |
| Cannavò, S | 1 |
| Gullo, D | 1 |
| Appelqvist, P | 1 |
| Kostianinen, S | 1 |
| Wagner, RA | 1 |
| Dorn, DP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma[NCT05344027] | 35 participants (Actual) | Observational | 2022-04-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Multiple thoracotomy combined with chemotherapy in metastatic adrenal cortical carcinoma: a case report and review of the literature.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Carcinoma; Cortisone; Cushing Syndrom | 1983 |
2 other studies available for thyroxine and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Mitotane treatment in patients with adrenocortical cancer causes central hypothyroidism.
Topics: Adrenal Cortex Neoplasms; Adult; Aged; Antineoplastic Agents, Hormonal; Female; Humans; Hypothyroidi | 2016 |
Evaluation of serum estradiol concentrations in alopecic ferrets with adrenal gland tumors.
Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alopecia; Animals; E | 1994 |