thyroxine has been researched along with Acute Post-Traumatic Stress Disorder in 8 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-traumatic stress disorder (PTSD) has been associated with dysregulation of the neuroendocrine system." | 2.73 | Changes in cortisol and DHEA plasma levels after psychotherapy for PTSD. ( Assies, J; de Vries, GJ; Gersons, BP; Güzelcan, Y; Olff, M, 2007) |
| "Women with PTSD-CSA showed significant elevations in Total T3 and the TT3/free thyroxine (TT3/FT4) ratio, the FT3/TT3 ratio, and modest reductions in thyroid stimulating hormone relative to our community sample." | 2.71 | Thyroid hormone alterations among women with posttraumatic stress disorder due to childhood sexual abuse. ( Friedman, MJ; Jalowiec, JE; McDonagh-Coyle, A; McHugo, GJ; Wang, S, 2005) |
| "Studies included 674 adults (373 PTSD, 301 controls)." | 2.66 | Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis. ( Borikar, M; Erwin, PJ; George, G; Mao, Y; Maraka, S; Menon, LP; Owen, RR; Toloza, FJK, 2020) |
| "Posttraumatic stress disorder (PTSD) has been associated with dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis as well as of the hypothalamus-pituitary-thyroid (HPT) axis." | 1.33 | HPA- and HPT-axis alterations in chronic posttraumatic stress disorder. ( Assies, J; de Vries, GJ; Gersons, BP; Güzelcan, Y; Olff, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Toloza, FJK | 1 |
| Mao, Y | 1 |
| Menon, LP | 1 |
| George, G | 1 |
| Borikar, M | 1 |
| Erwin, PJ | 1 |
| Owen, RR | 1 |
| Maraka, S | 1 |
| Kozarić-Kovacić, D | 1 |
| Karlović, D | 1 |
| Kocijan-Hercigonja, D | 1 |
| Friedman, MJ | 1 |
| Wang, S | 2 |
| Jalowiec, JE | 1 |
| McHugo, GJ | 1 |
| McDonagh-Coyle, A | 1 |
| Olff, M | 2 |
| Güzelcan, Y | 2 |
| de Vries, GJ | 2 |
| Assies, J | 2 |
| Gersons, BP | 2 |
| Bauer, M | 1 |
| Priebe, S | 1 |
| Kürten, I | 1 |
| Gräf, KJ | 1 |
| Baumgartner, A | 1 |
| Southwick, S | 1 |
| Mason, JW | 1 |
| Giller, EL | 1 |
| Kosten, TR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double-blind Placebo-controlled Cross-over Trial of Hydrocortisone for Post-traumatic Stress Disorder[NCT00706173] | Phase 4 | 0 participants (Actual) | Interventional | 2009-08-31 | Withdrawn (stopped due to Unable to recruit eligible subjects for the trial.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thyroxine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Association of Thyroid Function with Posttraumatic Stress Disorder: a Systematic Review and Meta-Analysis.
Topics: Adult; Humans; Stress Disorders, Post-Traumatic; Thyroid Function Tests; Thyroid Gland; Thyrotropin; | 2020 |
2 trials available for thyroxine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Thyroid hormone alterations among women with posttraumatic stress disorder due to childhood sexual abuse.
Topics: Adult; Child; Child Abuse, Sexual; Depression; Female; Humans; Neuropsychological Tests; Psychiatric | 2005 |
Changes in cortisol and DHEA plasma levels after psychotherapy for PTSD.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Life | 2007 |
5 other studies available for thyroxine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Elevation of serum total triiodothironine and free triiodothironine in Croatian veterans with combat-related post-traumatic stress disorder.
Topics: Adult; Croatia; Humans; Male; Middle Aged; Statistics, Nonparametric; Stress Disorders, Post-Traumat | 2002 |
Traumatic stress and thyroid function.
Topics: Humans; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Stress Disorders, Post-Traumatic; | 2006 |
HPA- and HPT-axis alterations in chronic posttraumatic stress disorder.
Topics: Adult; Aged; Chronic Disease; Cross-Sectional Studies; Depressive Disorder, Major; Female; Humans; H | 2006 |
Psychological and endocrine abnormalities in refugees from East Germany: Part I. Prolonged stress, psychopathology, and hypothalamic-pituitary-thyroid axis activity.
Topics: Adjustment Disorders; Anxiety Disorders; Depressive Disorder; Germany; Germany, East; Humans; Hypoth | 1994 |
Serum thyroxine change and clinical recovery in psychiatric inpatients.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depressive Disorder; Follow-Up Studies; Humans; Longitudi | 1989 |