thyroxine has been researched along with Acute Confusional Senile Dementia in 43 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of thyroid function in Alzheimer's disease (AD) has been subject to a number of studies during the last years." | 5.33 | Free thyroxine, cognitive decline and depression in Alzheimer's disease. ( Arlt, S; Mueller-Thomsen, T; Stuerenburg, HJ, 2006) |
| "Hypothyroidism and hyperthyroidism are commonly present conditions in adults, leading to neurological symptoms, affecting the central and peripheral nervous system, and to neurocognitive impairment." | 2.44 | Thyroid function, Alzheimer's disease and postoperative cognitive dysfunction: a tale of dangerous liaisons? ( Fodale, V; Mafrica, F, 2008) |
| "When hypothyroidism is detected in a patient with suspected dementia, thyroxin should be tried first of all." | 2.41 | [Dementia and hypothyroidism]. ( Fylkesnes, SI; Nygaard, HA, 2000) |
| "Alzheimer's disease may cause lung inflammation and treatment with low dose of T4 improved MDA level and lung inflammation." | 1.56 | Effects of levothyroxine on lung inflammation, oxidative stress and pathology in a rat model of Alzheimer's disease. ( Bavarsad, K; Boskabady, MH; Hadjzadeh, MA; Mohammadian Roshan, N; Saadat, S, 2020) |
| "An animal model of the Alzheimer's disease (AD) was established by intracerebroventricular injection of STZ (3 mg/kg) in male Wistar rats (250 ± 50 g)." | 1.56 | Effects of levothyroxine on learning and memory deficits in a rat model of Alzheimer's disease: the role of BDNF and oxidative stress. ( Ashaari, Z; Bafadam, S; Bavarsad, K; Beheshti, F; Hadjzadeh, MA; Hosseini, M; Pakdel, R, 2020) |
| "Clinical hypothyroidism was prevalent (>20% of individuals studied) and was associated with cerebrovascular disease but not Alzheimer's disease-type neuropathology." | 1.48 | Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. ( Brenowitz, WD; Han, F; Kukull, WA; Nelson, PT, 2018) |
| "The role of thyroid function in Alzheimer's disease (AD) has been subject to a number of studies during the last years." | 1.33 | Free thyroxine, cognitive decline and depression in Alzheimer's disease. ( Arlt, S; Mueller-Thomsen, T; Stuerenburg, HJ, 2006) |
| "Both hypothyroidism and Alzheimer's disease may be associated with elevated serum concentrations of thyroid stimulating hormone." | 1.28 | Effect of thyroid stimulating hormone on adaptive behaviour in Down's syndrome. ( Bhaumik, S; Collacott, RA; Garrick, P; Mitchell, C, 1991) |
| "These data suggest that autoimmune thyroiditis associated with a mild "subclinical" form of hypothyroidism is common in adult DS patients and more pronounced in patients with AD manifestations than in those without." | 1.28 | Autoimmune thyroiditis associated with mild "subclinical" hypothyroidism in adults with Down syndrome: a comparison of patients with and without manifestations of Alzheimer disease. ( Andrews, DF; Crapper McLachlan, DR; Dalton, AJ; Gera, E; Hummel, JT; Markovic, VD; Percy, ME; Rusk, AC; Somerville, MJ; Walfish, PG, 1990) |
| "Plasma ACTH in senile dementia of the Alzheimer's type was lower, but not significant as compared with that in normal controls." | 1.28 | High plasma levels of cortisol in patients with senile dementia of the Alzheimer's type. ( Kumahara, Y; Masugi, F; Morimoto, S; Nishide, M; Ogihara, T; Otsuka, A; Saeki, S; Sakaguchi, K; Tsuchiya, Y, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.60) | 18.7374 |
| 1990's | 2 (4.65) | 18.2507 |
| 2000's | 14 (32.56) | 29.6817 |
| 2010's | 11 (25.58) | 24.3611 |
| 2020's | 8 (18.60) | 2.80 |
| Authors | Studies |
|---|---|
| Quinlan, P | 3 |
| Horvath, A | 3 |
| Eckerström, C | 2 |
| Wallin, A | 4 |
| Svensson, J | 4 |
| Dolatshahi, M | 1 |
| Salehipour, A | 1 |
| Saghazadeh, A | 1 |
| Sanjeari Moghaddam, H | 1 |
| Aghamollaii, V | 1 |
| Fotouhi, A | 1 |
| Tafakhori, A | 1 |
| Qiu, M | 3 |
| Luo, F | 3 |
| Du, L | 3 |
| Ren, B | 1 |
| Ma, J | 1 |
| Tao, M | 1 |
| Jing, G | 1 |
| Han, S | 1 |
| Zhou, C | 1 |
| Wang, X | 1 |
| Wang, J | 1 |
| Bavarsad, K | 2 |
| Saadat, S | 1 |
| Mohammadian Roshan, N | 1 |
| Hadjzadeh, MA | 2 |
| Boskabady, MH | 1 |
| Li, LX | 1 |
| Yang, T | 1 |
| Guo, L | 1 |
| Wang, DY | 1 |
| Tang, CH | 1 |
| Li, Q | 1 |
| Yang, HM | 1 |
| Zhu, J | 1 |
| Zhang, LL | 1 |
| Chiaravalloti, A | 1 |
| Ursini, F | 1 |
| Fiorentini, A | 1 |
| Barbagallo, G | 1 |
| Martorana, A | 1 |
| Koch, G | 1 |
| Tavolozza, M | 1 |
| Schillaci, O | 1 |
| Shabani, S | 2 |
| Farbood, Y | 2 |
| Mard, SA | 1 |
| Sarkaki, A | 2 |
| Ahangarpour, A | 2 |
| Khorsandi, L | 2 |
| Brenowitz, WD | 1 |
| Han, F | 1 |
| Kukull, WA | 1 |
| Nelson, PT | 1 |
| Hosseini, M | 1 |
| Pakdel, R | 1 |
| Beheshti, F | 1 |
| Bafadam, S | 1 |
| Ashaari, Z | 1 |
| Chang, YS | 1 |
| Wu, YH | 1 |
| Wang, CJ | 1 |
| Tang, SH | 1 |
| Chen, HL | 1 |
| Chen, JM | 1 |
| Huang, CQ | 1 |
| Ai, M | 1 |
| Kuang, L | 1 |
| Accorroni, A | 1 |
| Giorgi, FS | 1 |
| Donzelli, R | 1 |
| Lorenzini, L | 1 |
| Prontera, C | 1 |
| Saba, A | 1 |
| Vergallo, A | 1 |
| Tognoni, G | 1 |
| Siciliano, G | 1 |
| Baldacci, F | 1 |
| Bonuccelli, U | 1 |
| Clerico, A | 1 |
| Zucchi, R | 1 |
| Ali Mard, S | 1 |
| Mafrica, F | 1 |
| Fodale, V | 1 |
| Ando, Y | 1 |
| Davis, JD | 2 |
| Podolanczuk, A | 1 |
| Donahue, JE | 1 |
| Stopa, E | 1 |
| Hennessey, JV | 1 |
| Luo, LG | 1 |
| Lim, YP | 1 |
| Stern, RA | 2 |
| Zhang, N | 1 |
| Du, HJ | 1 |
| Wang, JH | 1 |
| Cheng, Y | 1 |
| Johansson, P | 1 |
| Almqvist, EG | 1 |
| Johansson, JO | 1 |
| Mattsson, N | 1 |
| Hansson, O | 1 |
| Blennow, K | 1 |
| Zetterberg, H | 1 |
| Yong-Hong, L | 1 |
| Xiao-Dong, P | 1 |
| Chang-Quan, H | 1 |
| Bo, Y | 1 |
| Qing-Xiu, L | 1 |
| Döbert, N | 1 |
| Hamscho, N | 1 |
| Menzel, C | 1 |
| Peters, J | 1 |
| Frölich, L | 1 |
| Tsolakis, A | 1 |
| Zaplatnikov, K | 1 |
| Kratzsch, T | 1 |
| Diener, J | 1 |
| Maurer, K | 1 |
| Grünwald, F | 1 |
| van Osch, LA | 1 |
| Hogervorst, E | 1 |
| Combrinck, M | 1 |
| Smith, AD | 1 |
| Rogers, BL | 1 |
| Smith, KE | 1 |
| Harrington, CJ | 1 |
| Ott, BR | 1 |
| Jackson, IM | 1 |
| Prange, AJ | 1 |
| Guedj, E | 1 |
| Taïeb, D | 1 |
| De Laforte, C | 1 |
| Ceccaldi, M | 1 |
| Mundler, O | 1 |
| de Jong, FJ | 3 |
| den Heijer, T | 2 |
| Visser, TJ | 2 |
| de Rijke, YB | 1 |
| Drexhage, HA | 2 |
| Hofman, A | 3 |
| Breteler, MM | 4 |
| Peeters, RP | 1 |
| van der Deure, WM | 1 |
| Uitterlinden, AG | 1 |
| Stuerenburg, HJ | 1 |
| Arlt, S | 1 |
| Mueller-Thomsen, T | 1 |
| Masaki, K | 1 |
| Chen, H | 1 |
| Remaley, AT | 1 |
| Petrovitch, H | 1 |
| White, LR | 1 |
| Launer, LJ | 1 |
| Thase, ME | 1 |
| Fylkesnes, SI | 1 |
| Nygaard, HA | 1 |
| Kalmijn, S | 1 |
| Mehta, KM | 1 |
| Pols, HA | 1 |
| Bhaumik, S | 1 |
| Collacott, RA | 1 |
| Garrick, P | 1 |
| Mitchell, C | 1 |
| Percy, ME | 1 |
| Dalton, AJ | 1 |
| Markovic, VD | 1 |
| Crapper McLachlan, DR | 1 |
| Gera, E | 1 |
| Hummel, JT | 1 |
| Rusk, AC | 1 |
| Somerville, MJ | 1 |
| Andrews, DF | 1 |
| Walfish, PG | 1 |
| Thomas, R | 1 |
| Williams, P | 1 |
| John, R | 2 |
| Scanlon, M | 1 |
| Masugi, F | 1 |
| Ogihara, T | 1 |
| Sakaguchi, K | 1 |
| Otsuka, A | 1 |
| Tsuchiya, Y | 1 |
| Morimoto, S | 1 |
| Kumahara, Y | 1 |
| Saeki, S | 1 |
| Nishide, M | 1 |
| Bilikiewicz, A | 1 |
| Bidzan, L | 1 |
| Newhouse, PA | 1 |
| Sunderland, T | 1 |
| Tariot, PN | 1 |
| Mueller, EA | 1 |
| Murphy, DL | 1 |
| Cohen, RM | 1 |
| Thomas, DR | 1 |
| Hailwood, R | 1 |
| Harris, B | 1 |
| Williams, PA | 1 |
| Scanlon, MF | 1 |
| Peabody, CA | 1 |
| Thornton, JE | 1 |
| Tinklenberg, JR | 1 |
| Small, GW | 1 |
| Matsuyama, SS | 1 |
| Komanduri, R | 1 |
| Kumar, V | 1 |
| Jarvik, LF | 1 |
4 reviews available for thyroxine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Thyroid hormone levels in Alzheimer disease: a systematic review and meta-analysis.
Topics: Alzheimer Disease; Humans; Hypothyroidism; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Trii | 2023 |
Thyroid function, Alzheimer's disease and postoperative cognitive dysfunction: a tale of dangerous liaisons?
Topics: Aged; Alzheimer Disease; Brain; Cholinergic Fibers; Cognition Disorders; Delirium; Euthyroid Sick Sy | 2008 |
[Transthyretin: it's miracle function and pathogenesis].
Topics: Alzheimer Disease; Amyloid Neuropathies, Familial; Animals; Biomarkers, Tumor; Choroid Plexus; Human | 2009 |
[Dementia and hypothyroidism].
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Diagnosis, Differential | 2000 |
1 trial available for thyroxine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Preliminary study of the relationship between thyroid status and cognitive and neuropsychiatric functioning in euthyroid patients with Alzheimer dementia.
Topics: Affective Symptoms; Aged; Alzheimer Disease; Cognition Disorders; Cross-Sectional Studies; Donepezil | 2004 |
38 other studies available for thyroxine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Higher thyroid function is associated with accelerated hippocampal volume loss in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Hippocampus; Humans; Prospective Studies; Thyroid Function Tests; Thyroid G | 2022 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
Serum total and free T3 and CSF total T3 levels are significantly lower in Alzheimer Disease?
Topics: Alzheimer Disease; Humans; Thyroid Function Tests; Thyroxine; Triiodothyronine | 2023 |
The disturbance of thyroid-associated hormone and its receptors in brain and blood circulation existed in the early stage of mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Mice; Thyroid Gland; Thyroid Hormones; Thyrotropin; Thyrotropin-R | 2023 |
Effects of levothyroxine on lung inflammation, oxidative stress and pathology in a rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Male; Oxidative Stress; Pneumonia; Rats; Rats, W | 2020 |
Serum tau levels are increased in patients with hyperthyroidism.
Topics: Adult; Alzheimer Disease; Cognitive Dysfunction; Female; Humans; Hyperthyroidism; Male; Middle Aged; | 2020 |
Altered thyroid hormone profile in patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Thy | 2020 |
Functional correlates of TSH, fT3 and fT4 in Alzheimer disease: a F-18 FDG PET/CT study.
Topics: Aged; Alzheimer Disease; Brain; Case-Control Studies; Female; Fluorodeoxyglucose F18; Glucose; Human | 2017 |
The regulation of pituitary-thyroid abnormalities by peripheral administration of levothyroxine increased brain-derived neurotrophic factor and reelin protein expression in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain-Derived Neurotrophic Factor; Cell Adhesion Molecules, Neuronal; Di | 2018 |
Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atherosclerosis; Cerebrovascular Disorders; Drug Combina | 2018 |
Effects of levothyroxine on learning and memory deficits in a rat model of Alzheimer's disease: the role of BDNF and oxidative stress.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain-Derived Neurotrophic Factor; Disease Models, A | 2020 |
Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case-control study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Cholinesterase Inhibitors; Cogniti | 2018 |
Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cognitive Dysfunction; Dementia; Dementia, Vascular; Female; Follow-Up Stud | 2019 |
Circadian rhythm of TSH levels in subjects with Alzheimer's disease (AD).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Circadian Rhythm; Female; Humans; | 2013 |
Thyroid hormone levels in the cerebrospinal fluid correlate with disease severity in euthyroid patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Humans; Male; Mass Spectromet | 2017 |
Central and peripheral administrations of levothyroxine improved memory performance and amplified brain electrical activity in the rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain; Disease Models, Animal; Hippocampus; Neurons; | 2016 |
Thyroid hormone levels in the prefrontal cortex of post-mortem brains of Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autopsy; Case-Control Studies; Female; Humans; Male; Mid | 2008 |
A pilot study on the relationship between thyroid status and neuropsychiatric symptoms in patients with Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Female; Humans; Male; Middle Aged; Multivaria | 2012 |
Reduced cerebrospinal fluid level of thyroxine in patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognitive Dysfunction; Female; Humans; Male; Neuropsycho | 2013 |
Hypothalamic-pituitary-thyroid axis in patients with Alzheimer disease (AD).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Fasting; Female; Humans; Hypothala | 2013 |
Subclinical hyperthyroidism in dementia and correlation of the metabolic index in FDG-PET.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Metabolism; Brain; Female; Fluorodeoxyglucose F18; | 2003 |
Low thyroid-stimulating hormone as an independent risk factor for Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Alzheimer Disease; Apolipoproteins E; Cohort Studies; Com | 2004 |
[Thyroid diseases in the elderly].
Topics: Age Factors; Aged; Alzheimer Disease; Depressive Disorder; Humans; Hyperthyroidism; Hypothyroidism; | 2005 |
Similitude of brain perfusion pattern in hypothyroidism and early Alzheimer's disease: physiopathologic considerations.
Topics: Adult; Alzheimer Disease; Brain; Cerebrovascular Circulation; Diagnosis, Differential; Female; Human | 2005 |
Thyroid hormones, dementia, and atrophy of the medial temporal lobe.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amygdala; Atrophy; Cohort Studies; Dementia; Follow-Up S | 2006 |
The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amygdala; Atrophy; Early Diagnosis; Female; Genet | 2007 |
Free thyroxine, cognitive decline and depression in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Depression; Female; Humans; Hypothy | 2006 |
Thyroid function, the risk of dementia and neuropathologic changes: the Honolulu-Asia aging study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Asian; Brain; Cohort Studies; Comorbidity; Disease Progr | 2009 |
Reversible dementia in Down's syndrome.
Topics: Adult; Alzheimer Disease; Dementia; Diagnosis, Differential; Down Syndrome; Female; Humans; Hypothyr | 1982 |
Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study.
Topics: Aged; Alzheimer Disease; Autoantibodies; Dementia; Female; Follow-Up Studies; Humans; Hyperthyroidis | 2000 |
Effect of thyroid stimulating hormone on adaptive behaviour in Down's syndrome.
Topics: Adaptation, Psychological; Adult; Aged; Alzheimer Disease; Down Syndrome; Humans; Hypothyroidism; In | 1991 |
Autoimmune thyroiditis associated with mild "subclinical" hypothyroidism in adults with Down syndrome: a comparison of patients with and without manifestations of Alzheimer disease.
Topics: Adult; Aged; Alzheimer Disease; Antibodies; Down Syndrome; Female; Humans; Hypothyroidism; Male; Mic | 1990 |
Growth hormone responses to growth hormone releasing factor in primary degenerative dementia.
Topics: Aged; Alzheimer Disease; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Pro | 1989 |
High plasma levels of cortisol in patients with senile dementia of the Alzheimer's type.
Topics: Adrenocorticotropic Hormone; Aged; Alzheimer Disease; Blood Pressure; Cognition Disorders; Humans; H | 1989 |
[Changes in thyroid function in primary degenerative dementia processes].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Humans; Hydrocortisone; Male; Middle Aged; Neuro | 1989 |
Prolactin response to TRH in Alzheimer's disease and elderly controls.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Humans; Middle Aged; Prolactin; Sex Factors; Thyrotropi | 1986 |
Thyroid status in senile dementia of the Alzheimer type (SDAT).
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Female; Growth Hormone; Humans; Male; Prolactin; Thyroid | 1987 |
Progressive dementia associated with thyroid disease.
Topics: Aged; Alzheimer Disease; Female; Humans; Hypothyroidism; Thyroid Diseases; Thyroxine | 1986 |
Thyroid disease in patients with dementia of the Alzheimer type.
Topics: Aged; Alzheimer Disease; Female; Humans; Male; Thyroid Diseases; Thyroid Hormones; Thyroxine | 1985 |