thyroxine has been researched along with Acrocephaly in 7 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Acrocephaly: Premature closing of the lambdoid and coronal sutures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A proposed mechanism of craniosynostosis is the disruption of proliferation and differentiation of cells in the perisutural area." | 1.51 | Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion. ( Cray, J; Durham, E; Howie, RN; Larson, N; LaRue, A, 2019) |
| "Genetic murine models of craniosynostosis exist, but often imperfectly model human patients." | 1.43 | Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis. ( Bennfors, G; Black, L; Cray, JJ; Durham, EL; Elsalanty, M; Howie, RN; Parsons, TE; Weinberg, SM; Yu, JC, 2016) |
| "Hyperthyroidism is an established risk factor for osteoporosis." | 1.32 | A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone. ( Cheng, SY; Harvey, CB; Kaneshige, K; Kaneshige, M; O'Shea, PJ; Suzuki, H; Williams, GR, 2003) |
| "Various regimens of treatment for hypothyroidism are discussed with recommendations for avoiding this potentially hazardous complication of therapy." | 1.25 | Premature craniosynostosis-a complication of thyroid replacement therapy. ( Penfold, JL; Simpson, DA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Durham, E | 1 |
| Howie, RN | 2 |
| Larson, N | 1 |
| LaRue, A | 1 |
| Cray, J | 1 |
| Durham, EL | 1 |
| Black, L | 1 |
| Bennfors, G | 1 |
| Parsons, TE | 1 |
| Elsalanty, M | 1 |
| Yu, JC | 1 |
| Weinberg, SM | 1 |
| Cray, JJ | 1 |
| Kini, U | 1 |
| Hurst, JA | 1 |
| Byren, JC | 1 |
| Wall, SA | 1 |
| Johnson, D | 1 |
| Wilkie, AO | 1 |
| Hashmi, SS | 1 |
| Canfield, MA | 1 |
| Marengo, L | 1 |
| Moffitt, KB | 1 |
| Belmont, JW | 1 |
| Freedenberg, D | 1 |
| Tanksley, SM | 1 |
| Lupo, PJ | 1 |
| O'Shea, PJ | 1 |
| Harvey, CB | 1 |
| Suzuki, H | 1 |
| Kaneshige, M | 1 |
| Kaneshige, K | 1 |
| Cheng, SY | 1 |
| Williams, GR | 1 |
| Penfold, JL | 1 |
| Simpson, DA | 1 |
| Menking, M | 1 |
| Wiebel, J | 1 |
| Schmid, WU | 1 |
| Schmidt, WT | 1 |
| Ebel, KD | 1 |
| Ritter, R | 1 |
7 other studies available for thyroxine and Acrocephaly
| Article | Year |
|---|---|
Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion.
Topics: Animals; Citalopram; Craniosynostoses; Culture Media; Down-Regulation; Female; Male; Mice; Mice, Inb | 2019 |
Effects of thyroxine exposure on the Twist 1 +/- phenotype: A test of gene-environment interaction modeling for craniosynostosis.
Topics: Abnormalities, Drug-Induced; Animals; Craniosynostoses; Disease Models, Animal; Gene Expression Regu | 2016 |
Etiological heterogeneity and clinical characteristics of metopic synostosis: Evidence from a tertiary craniofacial unit.
Topics: Adolescent; Anticoagulants; Child; Child, Preschool; Chromosome Aberrations; Craniosynostoses; Enoxa | 2010 |
The association between neonatal thyroxine and craniosynostosis, Texas, 2004-2007.
Topics: Adult; Case-Control Studies; Craniosynostoses; Female; Humans; Infant, Newborn; Neonatal Screening; | 2012 |
A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone.
Topics: Animals; Animals, Newborn; Body Height; Bone and Bones; Bone Density; Bone Development; Craniosynost | 2003 |
Premature craniosynostosis-a complication of thyroid replacement therapy.
Topics: Child; Congenital Hypothyroidism; Craniosynostoses; Female; Head; Humans; Hypothyroidism; Infant; In | 1975 |
Premature craniosynostosis associated with hyperthyroidism in 4 children with reference to 5 further cases in the literature.
Topics: Bone Development; Child; Child, Preschool; Craniosynostoses; Female; Graves Disease; Growth; Humans; | 1972 |