Page last updated: 2024-11-06

thyroxine and Achlorhydria

thyroxine has been researched along with Achlorhydria in 2 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Achlorhydria: A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.

Research Excerpts

ExcerptRelevanceReference
" We therefore examined achlorhydria-related disparity in bioequivalence of levothyroxine and nifedipine formulations using virtual bioequivalence within a physiologically-based pharmacokinetic (PBPK) modelling framework."3.85Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria. ( Darwich, AS; Doki, K; Patel, N; Rostami-Hodjegan, A, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Doki, K1
Darwich, AS1
Patel, N1
Rostami-Hodjegan, A1
Fiorini, G1
Zullo, A1
Castelli, V1
Lo Re, G1
Holton, J1
Vaira, D1

Other Studies

2 other studies available for thyroxine and Achlorhydria

ArticleYear
Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Nov-15, Volume: 109

    Topics: Achlorhydria; Aged; Capsules; Drug Liberation; Female; Humans; Male; Middle Aged; Models, Biological

2017
Role of Helicobacter pylori infection in the thyroid diseases.
    Journal of gastrointestinal and liver diseases : JGLD, 2013, Volume: 22, Issue:3

    Topics: Achlorhydria; Administration, Oral; Animals; Biological Availability; Helicobacter Infections; Helic

2013