thyroxine has been researched along with Abnormality, Heart in 28 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Iodine exposure during cardiac catheterisation or surgery may induce transient hypothyroidism in term infants." | 9.08 | Iodine and hypothyroidism in neonates with congenital heart disease. ( Davidovitch, N; German, B; Hegesh, J; Kuint, J; Linder, N; Lubin, D; Sack, J; Sela, B, 1997) |
| "To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect." | 7.77 | Severe amiodarone-induced hypothyroidism in an infant. ( Panagiotopoulos, C; Sanatani, S; Trudel, K, 2011) |
| "Iodine exposure during cardiac catheterisation or surgery may induce transient hypothyroidism in term infants." | 5.08 | Iodine and hypothyroidism in neonates with congenital heart disease. ( Davidovitch, N; German, B; Hegesh, J; Kuint, J; Linder, N; Lubin, D; Sack, J; Sela, B, 1997) |
| "To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect." | 3.77 | Severe amiodarone-induced hypothyroidism in an infant. ( Panagiotopoulos, C; Sanatani, S; Trudel, K, 2011) |
| "This study compared 2 years of thyroxine treatment with placebo in 196 neonates with Down syndrome who were included in a previously reported randomized clinical trial." | 3.73 | Comorbidity, hospitalization, and medication use and their influence on mental and motor development of young infants with Down syndrome. ( de Vijlder, JJ; Heymans, HS; Tijssen, JG; van Trotsenburg, AS; Vulsma, T, 2006) |
| "Chronic hypoxia in our neonatal rat model was associated with decrease in growth hormone levels and an increase in corticosterone levels." | 3.72 | Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease. ( Azar, N; Azar, ST; Bitar, FF; Dbaibo, GS; Mroueh, S; Nasser, M; Obeid, M; Zayour, D, 2003) |
| "A woman receiving thyroxine substitution therapy for acquired hypothyroidism caused by autoimmune thyroiditis gave birth to three babies who had transient primary hypothyroidism." | 3.69 | Outcome in three siblings with antibody-mediated transient congenital hypothyroidism. ( Brown, RS; Dussault, JH; Gattereau, A; Glorieux, J; Huot, C; Pacaud, D; Van Vliet, G, 1995) |
| "Triiodothyronine is an important regulator of cellular metabolism and may have potential use as an inotropic agent." | 1.28 | The effects of cardiopulmonary bypass on thyroid function in infants weighing less than five kilograms. ( Donaghey, SF; Jamieson, MP; Logan, RW; Mitchell, IM; Paton, RD; Pollock, JC, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Ricci, S | 1 |
| Sarli, WM | 1 |
| Lodi, L | 1 |
| Canessa, C | 1 |
| Lippi, F | 1 |
| Azzari, C | 1 |
| Stagi, S | 1 |
| Luan, YL | 1 |
| Ou, YQ | 1 |
| Liu, XQ | 1 |
| Lin, S | 1 |
| Guo, Y | 1 |
| Lin, WH | 1 |
| Zhou, SJ | 1 |
| Chen, XH | 1 |
| Cao, H | 1 |
| Chen, Q | 1 |
| Flores, S | 1 |
| Checchia, PA | 1 |
| Talwar, S | 1 |
| Bhoje, A | 1 |
| Khadagawat, R | 1 |
| Chaturvedi, P | 1 |
| Sreenivas, V | 1 |
| Makhija, N | 1 |
| Sahu, M | 1 |
| Choudhary, SK | 1 |
| Airan, B | 1 |
| Kuwata, S | 1 |
| Takanashi, M | 1 |
| Hashimoto, M | 1 |
| Iwamoto, Y | 1 |
| Ishido, H | 1 |
| Masutani, S | 1 |
| Saiki, H | 1 |
| Sugamoto, K | 1 |
| Senzaki, H | 1 |
| Saad, NS | 1 |
| Floyd, K | 1 |
| Ahmed, AA | 1 |
| Mohler, PJ | 1 |
| Janssen, PM | 1 |
| Elnakish, MT | 1 |
| Dechant, MJ | 1 |
| van der Werf-Grohmann, N | 1 |
| Neumann, E | 1 |
| Spiekerkoetter, U | 1 |
| Stiller, B | 1 |
| Grohmann, J | 1 |
| El-Sisi, A | 1 |
| Khella, A | 1 |
| Numan, M | 1 |
| Dilwar, M | 1 |
| Bhat, A | 1 |
| Soliman, A | 1 |
| Trudel, K | 1 |
| Sanatani, S | 1 |
| Panagiotopoulos, C | 1 |
| Mıhçı, E | 1 |
| Akçurin, G | 1 |
| Eren, E | 1 |
| Kardelen, F | 1 |
| Akçurin, S | 1 |
| Keser, I | 1 |
| Ertuğ, H | 1 |
| Akçevin, A | 1 |
| Alkan-Bozkaya, T | 1 |
| Qiu, F | 1 |
| Undar, A | 1 |
| Bartkowski, R | 1 |
| Wojtalik, M | 1 |
| Korman, E | 1 |
| Sharma, G | 1 |
| Henschke, J | 1 |
| Mrówczyński, W | 1 |
| Zayour, D | 1 |
| Azar, ST | 1 |
| Azar, N | 1 |
| Nasser, M | 1 |
| Obeid, M | 1 |
| Mroueh, S | 1 |
| Dbaibo, GS | 1 |
| Bitar, FF | 1 |
| MIKULICICH, G | 1 |
| OESTER, YT | 1 |
| Lynch, BA | 1 |
| Brown, DM | 1 |
| Herrington, C | 1 |
| Braunlin, E | 1 |
| Dagan, O | 1 |
| Vidne, B | 1 |
| Josefsberg, Z | 1 |
| Phillip, M | 1 |
| Strich, D | 1 |
| Erez, E | 1 |
| van Trotsenburg, AS | 1 |
| Heymans, HS | 1 |
| Tijssen, JG | 1 |
| de Vijlder, JJ | 1 |
| Vulsma, T | 1 |
| Pacaud, D | 1 |
| Huot, C | 1 |
| Gattereau, A | 1 |
| Brown, RS | 1 |
| Glorieux, J | 1 |
| Dussault, JH | 1 |
| Van Vliet, G | 1 |
| Murzi, B | 1 |
| Iervasi, G | 1 |
| Masini, S | 1 |
| Moschetti, R | 1 |
| Vanini, V | 1 |
| Zucchelli, G | 1 |
| Biagini, A | 1 |
| Mainwaring, RD | 1 |
| Lamberti, JJ | 1 |
| Carter, TL | 1 |
| Nelson, JC | 1 |
| Brogan, TV | 1 |
| Bratton, SL | 1 |
| Lynn, AM | 1 |
| Linder, N | 1 |
| Sela, B | 1 |
| German, B | 1 |
| Davidovitch, N | 1 |
| Kuint, J | 1 |
| Hegesh, J | 1 |
| Lubin, D | 1 |
| Sack, J | 2 |
| Bialkowski, J | 1 |
| Siebner, R | 1 |
| Merlob, P | 1 |
| Kaiserman, I | 1 |
| Mitchell, IM | 1 |
| Pollock, JC | 1 |
| Jamieson, MP | 1 |
| Donaghey, SF | 1 |
| Paton, RD | 1 |
| Logan, RW | 1 |
| Andler, W | 1 |
| Heüveldop, A | 1 |
| Polichronidou, T | 1 |
| Krieger, I | 1 |
| Good, MH | 1 |
4 trials available for thyroxine and Abnormality, Heart
| Article | Year |
|---|---|
Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial.
Topics: Administration, Oral; Cardiac Surgical Procedures; Double-Blind Method; Female; Heart Defects, Conge | 2018 |
Evaluation of perfusion modes on vital organ recovery and thyroid hormone homeostasis in pediatric patients undergoing cardiopulmonary bypass.
Topics: Adolescent; Biomarkers; Cardiopulmonary Bypass; Cardiovascular Agents; Chi-Square Distribution; Chil | 2010 |
Thyroid function in infants following cardiac surgery: comparative effects of iodinated and noniodinated topical antiseptics.
Topics: Anti-Infective Agents, Local; Cardiopulmonary Bypass; Chlorhexidine; Female; Heart Defects, Congenit | 1997 |
Iodine and hypothyroidism in neonates with congenital heart disease.
Topics: Anti-Infective Agents, Local; Cardiac Catheterization; Contrast Media; Heart Defects, Congenital; Hu | 1997 |
24 other studies available for thyroxine and Abnormality, Heart
| Article | Year |
|---|---|
Characterization of Autoimmune Thyroid Disease in a Cohort of 73 Paediatric Patients Affected by 22q11.2 Deletion Syndrome: Longitudinal Single-Centre Study.
Topics: Adolescent; Child; Cohort Studies; DiGeorge Syndrome; Heart Defects, Congenital; Humans; Longitudina | 2022 |
Triclosan in paired-maternal and cord blood, and their relationships with congenital heart disease of baby.
Topics: Female; Fetal Blood; Heart Defects, Congenital; Humans; Maternal Exposure; Molecular Docking Simulat | 2023 |
Changes of serum TSH, FT3, and FT4 levels in infants received surgical correction of congenital heart disease under cardiopulmonary bypass.
Topics: Cardiopulmonary Bypass; Heart Defects, Congenital; Humans; Infant; Retrospective Studies; Thyroid Ho | 2023 |
Inflammatory and neurohormonal modulation for congenital heart surgery: The quest continues.
Topics: Dietary Supplements; Double-Blind Method; Heart Defects, Congenital; Heart Failure; Humans; Infant; | 2018 |
Thyroid Function in Patients With a Fontan Circulation.
Topics: Cardiac Catheterization; Child; Female; Follow-Up Studies; Fontan Procedure; Heart Defects, Congenit | 2019 |
The Effect of Sorafenib, Tadalafil and Macitentan Treatments on Thyroxin-Induced Hemodynamic Changes and Cardiac Abnormalities.
Topics: Animals; Blood Pressure; Cardiomyopathies; Disease Models, Animal; Echocardiography; Electrocardiogr | 2016 |
Thyroidal response following iodine excess for cardiac catheterisation and intervention in early infancy.
Topics: Cardiac Catheterization; Contrast Media; Female; Germany; Heart Defects, Congenital; Humans; Hypothy | 2016 |
Linear growth in relation to the circulating concentration of insulin-like growth factor-I and free thyroxine in infants and children with congenital cyanotic heart disease before vs. after surgical intervention.
Topics: Anthropometry; Body Height; Body Mass Index; Case-Control Studies; Female; Growth; Heart Defects, Co | 2009 |
Severe amiodarone-induced hypothyroidism in an infant.
Topics: Amiodarone; Female; Heart Defects, Congenital; Humans; Hypothyroidism; Infant; Thyroid Function Test | 2011 |
Evaluation of congenital heart diseases and thyroid abnormalities in children with Down syndrome.
Topics: Child; Child, Preschool; Chromosome Banding; Down Syndrome; Echocardiography; Female; Heart Defects, | 2010 |
Thyroid hormones levels in infants during and after cardiopulmonary bypass with ultrafiltration.
Topics: Cardiopulmonary Bypass; Critical Care; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; I | 2002 |
Endocrine changes in a rat model of chronic hypoxia mimicking cyanotic heart disease.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Animals, Newborn; Chronic Disease; Cortico | 2003 |
Hormonal influences on epinephrine induced aortic sclerosis.
Topics: Aorta; Aortic Diseases; Aortic Valve; Arteriosclerosis; Bicuspid Aortic Valve Disease; Disease; Epin | 1951 |
Thyroid dysfunction after pediatric cardiac surgery.
Topics: Cardiac Surgical Procedures; Chest Tubes; Drainage; Female; Heart Defects, Congenital; Humans; Hypot | 2004 |
Relationship between changes in thyroid hormone level and severity of the postoperative course in neonates undergoing open-heart surgery.
Topics: Biomarkers; Cardiac Surgical Procedures; Euthyroid Sick Syndromes; Heart Defects, Congenital; Heart- | 2006 |
Comorbidity, hospitalization, and medication use and their influence on mental and motor development of young infants with Down syndrome.
Topics: Child Development; Child, Preschool; Comorbidity; Congenital Hypothyroidism; Double-Blind Method; Do | 2006 |
Outcome in three siblings with antibody-mediated transient congenital hypothyroidism.
Topics: Adult; Child, Preschool; Congenital Hypothyroidism; Female; Follow-Up Studies; Heart Defects, Congen | 1995 |
Thyroid hormones homeostasis in pediatric patients during and after cardiopulmonary bypass.
Topics: Adolescent; Cardiopulmonary Bypass; Child; Child, Preschool; Female; Heart Defects, Congenital; Home | 1995 |
Reduction in triiodothyronine levels following modified Fontan procedure.
Topics: Atrial Function; Blood Pressure; Cardiopulmonary Bypass; Child, Preschool; Female; Follow-Up Studies | 1994 |
Use of thyroid hormones after cardiopulmonary bypass in children.
Topics: Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Male; Thyroid Hormones; Thyroxin | 1998 |
Congenital anomalies concomitant with persistent primary congenital hypothyroidism.
Topics: Congenital Abnormalities; Congenital Hypothyroidism; Female; Heart Defects, Congenital; Hip Dislocat | 1992 |
The effects of cardiopulmonary bypass on thyroid function in infants weighing less than five kilograms.
Topics: Body Weight; Cardiopulmonary Bypass; Female; Heart Defects, Congenital; Humans; Hypothyroidism; Infa | 1992 |
[Endocrinologic disorders in deletion of chromosome 18].
Topics: Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 18; Dwarfism, Pituitary; Female; Gro | 1992 |
Adrenocortical and thyroid function in the deprivation syndrome. Comparison with growth failure due to undernutrition, congenital heart disease, or prenatal influences.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Basal Metabolism; Body Heigh | 1970 |