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thyroxine and Abnormalities, Congenital

thyroxine has been researched along with Abnormalities, Congenital in 24 studies

Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.

Research Excerpts

ExcerptRelevanceReference
"To investigate whether fetal exposure to antithyroid drugs (ATD) and levothyroxine affects gestational age (GA), birth weight, birth length, head circumference and prevalence of congenital anomalies."7.83Pregnancy outcomes after fetal exposure to antithyroid medications or levothyroxine. ( Garne, E; Hansen, AV; Schurmann, L, 2016)
"Our purpose was to demonstrate that propylthiouracil and methimazole are equally effective and safe in the treatment of hyperthyroidism during pregnancy."7.69A comparison of propylthiouracil versus methimazole in the treatment of hyperthyroidism in pregnancy. ( Koonings, PP; Mestman, JH; Millar, LK; Montoro, MN; Wing, DA, 1994)
"To investigate whether fetal exposure to antithyroid drugs (ATD) and levothyroxine affects gestational age (GA), birth weight, birth length, head circumference and prevalence of congenital anomalies."3.83Pregnancy outcomes after fetal exposure to antithyroid medications or levothyroxine. ( Garne, E; Hansen, AV; Schurmann, L, 2016)
"Our purpose was to demonstrate that propylthiouracil and methimazole are equally effective and safe in the treatment of hyperthyroidism during pregnancy."3.69A comparison of propylthiouracil versus methimazole in the treatment of hyperthyroidism in pregnancy. ( Koonings, PP; Mestman, JH; Millar, LK; Montoro, MN; Wing, DA, 1994)
"Clinical hyperthyroidism was associated with hearing dysplasia; the adjusted odds ratio (95% CI) was 12."1.37Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China. ( Hao, JH; Huang, K; Li, T; Su, PY; Tao, FB; Xu, YH; Xu, YQ; Yan, SQ, 2011)
"In Germany, autoimmune thyroiditis usually manifests as atrophic thyroiditis with functional hypothyroidism affecting elderly women in particular."1.32[Diagnosis and treatment of autoimmune thyroiditis]. ( Janssen, OE; Lahner, H; Mann, K; Quadbeck, B, 2004)
"The adequate treatment of hypothyroidism during gestation minimizes risks and generally, makes it possible for pregnancies to be carried to term without complications."1.31Overt and subclinical hypothyroidism complicating pregnancy. ( Abalovich, M; Alcaraz, G; Garcia, A; Gutierrez, S; Levalle, O; Maccallini, G, 2002)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's2 (8.33)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schurmann, L1
Hansen, AV1
Garne, E1
Tonacchera, M1
De Marco, G1
Agretti, P1
Montanelli, L1
Di Cosmo, C1
Freitas Ferreira, AC1
Dimida, A1
Ferrarini, E1
Ramos, HE1
Ceccarelli, C1
Brozzi, F1
Pinchera, A1
Vitti, P1
Su, PY1
Huang, K1
Hao, JH1
Xu, YQ1
Yan, SQ1
Li, T1
Xu, YH1
Tao, FB1
KLEINFELD, M1
ROSENTHAL, A1
STEIN, E1
STOLL, R1
BERNES-LASSERRE, M1
MARAUD, R1
FISHER, DA1
HOLLANDER, CS1
PROUT, TE1
RIENHOFF, M1
RUBEN, RJ1
ASPER, SP1
ARNOLD, WH1
Lahner, H1
Quadbeck, B1
Janssen, OE1
Mann, K1
Wing, DA1
Millar, LK1
Koonings, PP1
Montoro, MN1
Mestman, JH1
Müller, T1
Rehn, M1
Girschick, G1
Kristen, P1
Dietl, J1
Sharma, R1
Mondal, A1
Popli, M1
Sahoo, M1
Malhotra, N1
Soni, S1
Abalovich, M1
Gutierrez, S1
Alcaraz, G1
Maccallini, G1
Garcia, A1
Levalle, O1
Burman, KD1
Adler, RA1
Wartofsky, L1
Siebner, R1
Merlob, P1
Kaiserman, I1
Sack, J1
Skjöldebrand Sparre, LS1
Harakawa, S1
Akazawa, S1
Akazawa, M1
Hashimoto, M1
Yamashita, S1
Izumi, M1
Nagataki, S1
Fernhoff, PM1
Brown, AL1
Elsas, LJ1
Hayek, A1
Chapman, EM1
Crawford, JD1
Brisman, R1
Hughes, JE1
Holub, DA1
Pierpaoli, W1
Sorkin, E1
van Riet, HG1
Kal, J1
Haspels, AA1
Ridgway, EC1
Weintraub, BD1
Maloof, F1
Smith, JD1
Cagas, CR1
Seely, JR1
Neeman, J1

Reviews

1 review available for thyroxine and Abnormalities, Congenital

ArticleYear
[Diabetes and pregnancy].
    Nederlands tijdschrift voor geneeskunde, 1974, Jan-26, Volume: 118, Issue:4

    Topics: Abortion, Spontaneous; Congenital Abnormalities; Estrogens; Female; Fetal Death; Growth Hormone; Hum

1974

Other Studies

23 other studies available for thyroxine and Abnormalities, Congenital

ArticleYear
Pregnancy outcomes after fetal exposure to antithyroid medications or levothyroxine.
    Early human development, 2016, Volume: 101

    Topics: Adult; Birth Weight; Case-Control Studies; Congenital Abnormalities; Denmark; Female; Humans; Infant

2016
Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Adolescent; Adult; Aged; Birth Weight; Cesarean Section; Child; Congenital Abnormalities; Dual Oxida

2009
Maternal thyroid function in the first twenty weeks of pregnancy and subsequent fetal and infant development: a prospective population-based cohort study in China.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Adult; Child Development; China; Cohort Studies; Congenital Abnormalities; Female; Fetal Development

2011
Comparative effects of DL-thyronine, L-triiodothyronine and L-thyroxine on the isolated perfused frog heart.
    The American journal of physiology, 1958, Volume: 195, Issue:1

    Topics: Amino Acids, Aromatic; Animals; Anura; Congenital Abnormalities; Heart; Thyroid Hormones; Thyronines

1958
[Action of thyroxin on the teratogenic activity of a radiomimetic substance].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1962, Volume: 156

    Topics: Antineoplastic Agents; Congenital Abnormalities; Humans; Teratogenesis; Teratogens; Thyroxine

1962
MANAGEMENT OF HYPOTHYROIDISM DURING INFANCY AND CHILDHOOD.
    Modern treatment, 1964, Volume: 1

    Topics: Adolescent; Alkaline Phosphatase; Antithyroid Agents; Body Height; Body Weight; Child; Cholesterol;

1964
CONGENITAL DEAFNESS AND GOITER. STUDIES OF A PATIENT WITH A COCHLEAR DEFECT AND INADEQUATE FORMATION OF IODOTHYRONINES.
    The American journal of medicine, 1964, Volume: 37

    Topics: Cochlea; Congenital Abnormalities; Deafness; Diiodotyrosine; Goiter; Hearing Loss; Humans; Iodine Is

1964
[The effects of hormone medication, especially thyroxin on the eruption of retained teeth].
    Deutsche Stomatologie, 1955, Volume: 5, Issue:2

    Topics: Congenital Abnormalities; Exanthema; Foreign Bodies; Thyroxine; Tooth Abnormalities; Tooth Eruption

1955
[Diagnosis and treatment of autoimmune thyroiditis].
    MMW Fortschritte der Medizin, 2004, Feb-05, Volume: 146, Issue:6

    Topics: Adult; Aged; Autoantibodies; Congenital Abnormalities; Diagnosis, Differential; Female; Humans; Hypo

2004
A comparison of propylthiouracil versus methimazole in the treatment of hyperthyroidism in pregnancy.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Chi-Square Distribution; Cohort Studies; Congenital Abnormalities; Female; Follow-Up Studies; Humans

1994
Normalisation of a severely abnormal ductus venosus Doppler flow velocity waveform in a growth-retarded fetus with absent end-diastolic flow in the umbilical artery and congenital anomalies.
    Journal of perinatal medicine, 2001, Volume: 29, Issue:2

    Topics: Adult; Blood Flow Velocity; Congenital Abnormalities; Diabetes Mellitus, Type 1; Diastole; Fatal Out

2001
Hemiagenesis of the thyroid associated with chronic lymphocytic thyroiditis.
    Clinical nuclear medicine, 2001, Volume: 26, Issue:6

    Topics: Adult; Chronic Disease; Congenital Abnormalities; Female; Follow-Up Studies; Humans; Radionuclide Im

2001
Overt and subclinical hypothyroidism complicating pregnancy.
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:1

    Topics: Abortion, Spontaneous; Adolescent; Adult; Congenital Abnormalities; Congenital Hypothyroidism; Femal

2002
Hemiagenesis of the thyroid gland.
    The American journal of medicine, 1975, Volume: 58, Issue:1

    Topics: Adult; Congenital Abnormalities; Female; Graves Disease; Humans; Hyperthyroidism; Iodine Radioisotop

1975
Congenital anomalies concomitant with persistent primary congenital hypothyroidism.
    American journal of medical genetics, 1992, Sep-01, Volume: 44, Issue:1

    Topics: Congenital Abnormalities; Congenital Hypothyroidism; Female; Heart Defects, Congenital; Hip Dislocat

1992
Maternal free thyroxine and thyroxine-binding globulin during pregnancy ending in congenital malformations in the offspring.
    Gynecologic and obstetric investigation, 1989, Volume: 27, Issue:1

    Topics: Congenital Abnormalities; Female; Humans; Pregnancy; Pregnancy Trimester, First; Retrospective Studi

1989
Changes of serum thyroid hormone levels induce malformations on early embryogenesis in rats.
    Acta endocrinologica, 1989, Volume: 121, Issue:5

    Topics: Animals; Cell Differentiation; Cells, Cultured; Congenital Abnormalities; Culture Media; Female; Mat

1989
Congenital hypothyroidism: increased risk of neonatal morbidity results in delayed treatment.
    Lancet (London, England), 1987, Feb-28, Volume: 1, Issue:8531

    Topics: Congenital Abnormalities; Congenital Hypothyroidism; Humans; Hypothyroidism; Infant; Infant, Newborn

1987
Long-term results of treatment of thyrotoxicosis in children and adolescents with radioactive iodine.
    The New England journal of medicine, 1970, Oct-29, Volume: 283, Issue:18

    Topics: Adolescent; Age Factors; Child; Chronic Disease; Congenital Abnormalities; Female; Follow-Up Studies

1970
Endocrine function in nineteen patients with empty sella syndrome.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:3

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Cerebrospinal Fl

1972
Alterations of adrenal cortex and thyroid in mice with congenital absence of the thymus.
    Nature: New biology, 1972, Aug-30, Volume: 238, Issue:87

    Topics: Adrenal Glands; Age Factors; Animals; Congenital Abnormalities; Female; Male; Mice; Microscopy, Elec

1972
Metabolic clearance and production rates of human thyrotropin.
    The Journal of clinical investigation, 1974, Volume: 53, Issue:3

    Topics: Adult; Aged; Congenital Abnormalities; Female; Goiter, Nodular; Humans; Hyperthyroidism; Hypothyroid

1974
Defective iodide organification in "cryptothyroidism".
    The Journal of the Oklahoma State Medical Association, 1970, Volume: 63, Issue:5

    Topics: Child; Congenital Abnormalities; Congenital Hypothyroidism; Female; Goiter; Humans; Iodine; Metaboli

1970