thymosin-beta(4) has been researched along with Disease-Resistance* in 1 studies
1 other study(ies) available for thymosin-beta(4) and Disease-Resistance
Article | Year |
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Ectopic Expression of Human Thymosin β4 Confers Resistance to Legionella pneumophila during Pulmonary and Systemic Infection in Mice.
Thymosin beta-4 (Tβ4) is an actin-sequestering peptide that plays important roles in regeneration and remodeling of injured tissues. However, its function in a naturally occurring pathogenic bacterial infection model has remained elusive. We adopted Tβ4-overexpressing transgenic (Tg) mice to investigate the role of Tβ4 in acute pulmonary infection and systemic sepsis caused by Topics: Animals; Cytokines; Disease Models, Animal; Disease Resistance; Ectopic Gene Expression; Host-Pathogen Interactions; Humans; Immunohistochemistry; Immunophenotyping; Legionella pneumophila; Legionnaires' Disease; Ligands; Male; Mice; Mice, Transgenic; Pneumonia, Bacterial; Sepsis; Thymosin; Toll-Like Receptors | 2021 |