thymosin and Cocarcinogenesis

thymosin has been researched along with Cocarcinogenesis* in 2 studies

Other Studies

2 other study(ies) available for thymosin and Cocarcinogenesis

Article	Year
Thymosin fraction 5 does not influence urinary tract carcinogenesis by phenacetin and N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice. Oncology research, 1995, Volume: 7, Issue:3-4 The effect of thymosin fraction 5 (TF5) on the promotion and progression phases of urinary tract carcinogenesis induced by consecutive administration of phenacetin and N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) in NON/Shi mice was investigated. The study was carried out twice with a minor modification to the protocol in the second experiment. Fifty-seven male NON/Shi mice in experiment 1 and 100 mice in experiment 2 were each divided into four groups. Phenacetin was administered for 8 weeks in experiment 1 and 12 weeks in experiment 2, and subsequently BBN was given for 6 weeks in both cases, for total observation periods of 30 and 34 weeks, respectively. Sixty micrograms of TF5 per mouse was inoculated subcutaneously twice a week during (group 2) or after (group 3) BBN exposure, or both periods (group 4). Group 1 served as a control group without TF5 treatment. Histopathological examination revealed no effects on either induction of urinary tract carcinomas or distant metastasis from renal pelvic carcinomas in either experiment. Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Concanavalin A; Drug Interactions; Lymphocytes; Male; Mice; Mice, Inbred Strains; Phenacetin; Phytohemagglutinins; Spleen; Thymosin; Urologic Neoplasms	1995
[Dependence of the cocarcinogenic action of the influenza virus on the nature of the influenza infection]. Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:8 It was shown in experiments of CC57W mice that cocarcinogenic activity of influenza A/PR8/34 virus correlates with acute or chronic pattern of infection. Prolonged persistence of the virus resulted in significant stimulation of the lung tumor incidence in infected mice. The prevention with thymosin of chronic influenza infection development in CC57W mice lead to a decrease in the incidence of lung tumors to the control level. Topics: Animals; Cocarcinogenesis; Influenza A virus; Lung Neoplasms; Mice; Orthomyxoviridae Infections; Thymosin; Time Factors	1984

Article

Year

Thymosin fraction 5 does not influence urinary tract carcinogenesis by phenacetin and N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice.

Oncology research, 1995, Volume: 7, Issue:3-4

The effect of thymosin fraction 5 (TF5) on the promotion and progression phases of urinary tract carcinogenesis induced by consecutive administration of phenacetin and N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) in NON/Shi mice was investigated. The study was carried out twice with a minor modification to the protocol in the second experiment. Fifty-seven male NON/Shi mice in experiment 1 and 100 mice in experiment 2 were each divided into four groups. Phenacetin was administered for 8 weeks in experiment 1 and 12 weeks in experiment 2, and subsequently BBN was given for 6 weeks in both cases, for total observation periods of 30 and 34 weeks, respectively. Sixty micrograms of TF5 per mouse was inoculated subcutaneously twice a week during (group 2) or after (group 3) BBN exposure, or both periods (group 4). Group 1 served as a control group without TF5 treatment. Histopathological examination revealed no effects on either induction of urinary tract carcinomas or distant metastasis from renal pelvic carcinomas in either experiment.

Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Concanavalin A; Drug Interactions; Lymphocytes; Male; Mice; Mice, Inbred Strains; Phenacetin; Phytohemagglutinins; Spleen; Thymosin; Urologic Neoplasms

1995

[Dependence of the cocarcinogenic action of the influenza virus on the nature of the influenza infection].

Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:8

It was shown in experiments of CC57W mice that cocarcinogenic activity of influenza A/PR8/34 virus correlates with acute or chronic pattern of infection. Prolonged persistence of the virus resulted in significant stimulation of the lung tumor incidence in infected mice. The prevention with thymosin of chronic influenza infection development in CC57W mice lead to a decrease in the incidence of lung tumors to the control level.

Topics: Animals; Cocarcinogenesis; Influenza A virus; Lung Neoplasms; Mice; Orthomyxoviridae Infections; Thymosin; Time Factors

1984