Page last updated: 2024-08-21

thymoquinone and Triple Negative Breast Neoplasms

thymoquinone has been researched along with Triple Negative Breast Neoplasms in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (23.53)24.3611
2020's13 (76.47)2.80

Authors

AuthorsStudies
Cheng, J; Fu, J; Fu, S; Liu, X; Peng, J; Wang, Q; Wei, C; Xiao, T; Xie, X; Zou, H1
Adinew, GM; Badisa, RB; Elhag, R; Mazzio, EA; Mochona, B; Soliman, KFA; Taka, E1
A, P; B, SR; K, K; P, H; S, S; Sjs, B1
Adinew, GM; Antonie, LM; Badisa, RB; Messeha, SS; Soliman, KFA; Taka, E1
Adinew, G; Badisa, R; Messeha, SS; Soliman, KFA; Taka, E1
Fu, J; Khan, MA; Li, J; Tania, M; Zheng, M1
Adinew, GM; Badisa, RB; Messeha, SS; Soliman, KFA; Taka, E1
Adinew, GM; Messeha, S; Mochona, B; Redda, KK; Soliman, KFA; Taka, E1
Eissa, RA; El Tayebi, HM; Elgohary, S1
Ahmad, FJ; Akhter, S; Garg, N; Kumar Jain, G; Selvapandiyan, A; Zafar, S1
Adhikary, A; Ahir, M; Bhattacharjee, M; Bhattacharya, S; Chattopadhyay, S; Debnath, GH; Ghosh, A; Ghosh, S; Gupta, P; Maiti, S; Mukherjee, P1
Çınar, V; Delibaşı, N; Gökçe, S; Güler, A; Hamurcu, Z; Nurdinov, N; Ozpolat, B; Ünal, TD1
Chen, HC; Fu, J; Junaid, M; Khan, MA; Mei, Z; Tania, M; Zheng, M1
Ahmad, FJ; Ahmad, J; Barkat, MA; Beg, S; Khan, MA1
Bayraktar, R; Calin, GA; Kabil, N; Kahraman, N; Lopez-Berestein, G; Mokhlis, HA; Ozpolat, B1
Greenshields, AL; Hoskin, DW; Sutton, KM1
Aksu, H; Çakır, M; Canatan, H; İskender, B; İzgi, K; Kurt, B; Şakalar, Ç; Sezen, S; Turan, A1

Reviews

2 review(s) available for thymoquinone and Triple Negative Breast Neoplasms

ArticleYear
Therapeutic Potential of Thymoquinone in Triple-Negative Breast Cancer Prevention and Progression through the Modulation of the Tumor Microenvironment.
    Nutrients, 2021, Dec-25, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Female; Humans; Phytotherapy; Triple Negative Breast Neoplasms; Tumor Microenvironment

2021
Insights into the Targeting Potential of Thymoquinone for Therapeutic Intervention Against Triple-negative Breast Cancer.
    Current drug targets, 2018, Volume: 19, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Clinical Trials as Topic; Female; Humans; Molecular Targeted Therapy; Nigella sativa; Seeds; Triple Negative Breast Neoplasms

2018

Other Studies

15 other study(ies) available for thymoquinone and Triple Negative Breast Neoplasms

ArticleYear
TQFL12, a novel synthetic derivative of TQ, inhibits triple-negative breast cancer metastasis and invasion through activating AMPK/ACC pathway.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:21

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Drug Tapering; Humans; Mice; Models, Molecular; Protein Binding; Signal Transduction; Structure-Activity Relationship; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2021
Modulation of gene expression by thymoquinone conjugated zinc oxide nanoparticles arrested cell cycle, DNA damage and increased apoptosis in triple negative breast cancer cell line MDA-MB-231.
    Drug development and industrial pharmacy, 2021, Volume: 47, Issue:12

    Topics: Apoptosis; Benzoquinones; Cell Cycle; Cell Line, Tumor; DNA Damage; Gene Expression; Humans; Triple Negative Breast Neoplasms; Zinc Oxide

2021
Thymoquinone Alterations of the Apoptotic Gene Expressions and Cell Cycle Arrest in Genetically Distinct Triple-Negative Breast Cancer Cells.
    Nutrients, 2022, May-19, Volume: 14, Issue:10

    Topics: Benzoquinones; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Humans; TNF Receptor-Associated Factor 2; Triple Negative Breast Neoplasms

2022
Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD-L1 in MDA-MB-231 Triple-Negative Breast Cancer Cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36 Suppl 1

    Topics: B7-H1 Antigen; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; NF-E2-Related Factor 2; Triple Negative Breast Neoplasms; Up-Regulation

2022
Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro.
    BMC cancer, 2022, Jun-27, Volume: 22, Issue:1

    Topics: Benzoquinones; Cell Line, Tumor; Female; Humans; Neoplastic Processes; Receptors, Interleukin; Triple Negative Breast Neoplasms

2022
Anticancer Effects of Thymoquinone through the Antioxidant Activity, Upregulation of Nrf2, and Downregulation of PD-L1 in Triple-Negative Breast Cancer Cells.
    Nutrients, 2022, Nov-13, Volume: 14, Issue:22

    Topics: Antioxidants; B7-H1 Antigen; Down-Regulation; Glutathione; Humans; Hydrogen Peroxide; NF-E2-Related Factor 2; RNA, Messenger; Triple Negative Breast Neoplasms; Up-Regulation

2022
Thymoquinone Inhibition of Chemokines in TNF-α-Induced Inflammatory and Metastatic Effects in Triple-Negative Breast Cancer Cells.
    International journal of molecular sciences, 2023, Jun-08, Volume: 24, Issue:12

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemokines; Humans; Triple Negative Breast Neoplasms; Tumor Microenvironment; Tumor Necrosis Factor-alpha

2023
Thymoquinone, a Novel Multi-Strike Inhibitor of Pro-Tumorigenic Breast Cancer (BC) Markers: CALR, NLRP3 Pathway and sPD-L1 in PBMCs of HR+ and TNBC Patients.
    International journal of molecular sciences, 2023, Sep-19, Volume: 24, Issue:18

    Topics: Calreticulin; Carcinogenesis; Humans; Leukocytes, Mononuclear; NLR Family, Pyrin Domain-Containing 3 Protein; Triple Negative Breast Neoplasms

2023
Co-encapsulation of docetaxel and thymoquinone in mPEG-DSPE-vitamin E TPGS-lipid nanocapsules for breast cancer therapy: Formulation optimization and implications on cellular and in vivo toxicity.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 148

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanocapsules; Phosphatidylethanolamines; Polyethylene Glycols; Triple Negative Breast Neoplasms; Vitamin E

2020
Delivery of thymoquinone through hyaluronic acid-decorated mixed Pluronic® nanoparticles to attenuate angiogenesis and metastasis of triple-negative breast cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 06-10, Volume: 322

    Topics: Animals; Benzoquinones; Cell Line, Tumor; Chick Embryo; Humans; Hyaluronic Acid; Mice; MicroRNAs; Nanoparticles; Poloxamer; Triple Negative Breast Neoplasms

2020
Thymoquinone Inhibits Proliferation and Migration of MDA-MB-231 Triple Negative Breast Cancer Cells by Suppressing Autophagy, Beclin-1 and LC3.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:3

    Topics: Antineoplastic Agents; Autophagy; Beclin-1; Benzoquinones; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Microtubule-Associated Proteins; Molecular Structure; Structure-Activity Relationship; Triple Negative Breast Neoplasms; Tumor Cells, Cultured

2021
Synergistic Role of Thymoquinone on Anticancer Activity of 5-Fluorouracil in Triple Negative Breast Cancer Cells.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:6

    Topics: Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Fluorouracil; Humans; Triple Negative Breast Neoplasms

2022
Thymoquinone inhibits cell proliferation, migration, and invasion by regulating the elongation factor 2 kinase (eEF-2K) signaling axis in triple-negative breast cancer.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:3

    Topics: Animals; Benzoquinones; Cell Line, Tumor; Cell Movement; Cell Proliferation; Elongation Factor 2 Kinase; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; RNA, Messenger; Signal Transduction; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2018
Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.
    Nutrition and cancer, 2014, Volume: 66, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Carum; Caspases; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; G1 Phase Cell Cycle Checkpoints; Genes, p53; Humans; Membrane Potential, Mitochondrial; Mutation; Seeds; Triple Negative Breast Neoplasms

2014
The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Benzoquinones; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Screening Assays, Antitumor; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Triple Negative Breast Neoplasms; Tumor Burden

2016