thymoquinone has been researched along with Neoplasms in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.82) | 29.6817 |
| 2010's | 25 (56.82) | 24.3611 |
| 2020's | 16 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Asemi, Z; Homayoonfal, M; Yousefi, B | 1 |
| Goh, BH; Phua, CYH; Tang, YQ; Teoh, ZL; Yap, WH | 1 |
| Alam, M; Ansari, MM; Hasan, GM; Hassan, MI; Sharma, R; Yadav, DK | 1 |
| Afzal, S; Banday, N; Farooq, S; Maqbool, M; Mir, PA; Mir, RH; Mohi-Ud-Din, R; Raza, SN | 1 |
| Attar, R; Farooqi, AA; Xu, B | 1 |
| Hosseinzadeh, H; Imenshahidi, M; Sadeghi, E | 1 |
| Fu, J; Khan, MA; Tania, M | 1 |
| Ahmed, FR; Akter, Z; Khan, MA; Tania, M | 1 |
| Almatroodi, SA; Almatroudi, A; Alsahli, MA; Khan, AA; Rahmani, AH | 1 |
| Al Jaouni, SK; El-Far, AH; Mousa, SA; Tantawy, MA | 1 |
| Afrose, SS; Akter, Y; Junaid, M; Khan, MA; Tania, M; Zheng, M | 1 |
| Afrose, SS; Akter, Y; Junaid, M; Khan, MA; Tania, M | 1 |
| Amin, NS; El Tayebi, HM; Elgohary, S; Elkhodiry, AA; Stein, U | 1 |
| Alvarez-Suarez, JM; Ansary, J; Battino, M; Cianciosi, D; Forbes-Hernandez, TY; Garcia Villena, E; Giampieri, F; Gracia Villar, S; Quinzi, D; Regolo, L; Tutusaus Pifarre, K | 1 |
| Abdullah, O; Alhosin, M; Bronner, C; Hamiche, A; Hosawi, S; Omran, Z | 1 |
| Choiri, AA; Widiandani, T; Wulandari, AA | 1 |
| Kapoor, VK; Malik, S; Negi, P; Singh, A | 1 |
| Archambault, V; Normandin, K | 1 |
| Benz, PM; Butt, E; Gambaryan, S; Mindukshev, I; Nikolaev, VO; Rukoyatkina, N; Subramanian, H; Walter, U | 1 |
| Ahn, KS; Arfuso, F; Bishayee, A; Goh, BC; Kumar, AP; Sethi, G; Shanmugam, MK; Wang, L | 1 |
| Ballout, F; Fatfat, M; Gali-Muhtasib, H; Habli, Z; Rahal, ON | 1 |
| Akbas, F; Demirel, MH; Meral, I; Pala, M; Ustunova, S; Yildiz, C | 1 |
| Abu-Izneid, T; Fatmawati, S; Gondal, TA; Imran, A; Imran, M; Khan, IA; Qaisrani, TB; Rahman, KU; Rauf, A; Shahbaz, M | 1 |
| Abdelrazek, HMA; Mahmoud, YK | 1 |
| El-Baba, CO; Fakhoury, IH; Gali-Muhtasib, HU; Schneider-Stock, R; Zaki, AM | 1 |
| Asghar, S; Lv, H; Salmani, JM; Zhou, J | 1 |
| Aruoma, OI; Chun, KS; Kundu, J; Kundu, JK | 1 |
| El-Far, AH | 1 |
| Canatan, H; Iskender, B; Izgi, K | 1 |
| Li, HB; Li, S; Li, Y; Xu, DP; Zheng, J; Zhou, Y | 1 |
| Aggarwal, BB; Cho, SG; Liu, M; Pang, X; Rodriguez, M; Sethi, G; Wang, Y; Yi, T; Yi, Z | 1 |
| Effenberger-Neidnicht, K; Schobert, R | 1 |
| Azmi, A; Banerjee, S; Kucuk, O; Mohammad, RM; Padhye, S; Philip, PA; Sarkar, FH; Wang, Z | 1 |
| Breyer, S; Diestel, R; Effenberger-Neidnicht, K; Mahal, K; Sasse, F; Schobert, R | 1 |
| Berg, T; Hofmann, M; Krämer, A; Kreis, NN; Reindl, W; Sanhaji, M; Strebhardt, K; Yuan, J; Zimmer, B | 1 |
| Kumar, AP; Sethi, G; Tan, KH; Woo, CC | 1 |
| Heuberger, AL; Kester, AC; Reddivari, L; Vanamala, J | 1 |
| Al-Hoshan, M; badr, G; El-Toni, AM; Ibrahim, MA; Khan, A; Labis, JP; Sato, T; Yin, S | 1 |
| Chen, HC; Khan, MA; Tania, M; Zhang, DZ | 1 |
| Adem, A; Al Safi, M; Al Sultan, MA; Al-Salam, S; Arafat, K; Attoub, S; Raza, H; Sperandio, O; Takahashi, T | 1 |
| Bao, JL; Chen, XP; Huang, MQ; Lu, JJ; Wang, YT; Wu, GS; Xu, WS | 1 |
| Gali-Muhtasib, H; Roessner, A; Schneider-Stock, R | 1 |
| Ivankovic, S; Jukic, M; Jurin, M; Milos, M; Stojkovic, R | 1 |
31 review(s) available for thymoquinone and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
Targeting microRNAs with thymoquinone: a new approach for cancer therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Humans; MicroRNAs; Neoplasms; Nigella sativa | 2021 |
Triangulating the pharmacological properties of thymoquinone in regulating reactive oxygen species, inflammation, and cancer: Therapeutic applications and mechanistic pathways.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Clinical Trials as Topic; Humans; Inflammation; Inflammation Mediators; Neoplasms; Reactive Oxygen Species; Signal Transduction | 2021 |
Therapeutic implications and clinical manifestations of thymoquinone.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzoquinones; Cell Line, Tumor; Humans; Neoplasms; Nigella sativa | 2022 |
Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from
Topics: Antineoplastic Agents; Benzoquinones; Biological Products; Humans; Janus Kinases; Neoplasms; Nigella sativa; Prospective Studies; Reactive Oxygen Species | 2022 |
Anticancer and Anti-Metastatic Role of Thymoquinone: Regulation of Oncogenic Signaling Cascades by Thymoquinone.
Topics: Animals; Benzoquinones; Biological Products; Carcinogenesis; Neoplasms; Signal Transduction | 2022 |
Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review.
Topics: AMP-Activated Protein Kinases; Antioxidants; Benzoquinones; Humans; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Nigella sativa; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins c-akt; Signal Transduction | 2023 |
Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; DNA Methylation; Epigenesis, Genetic; Histones; Humans; Neoplasms; RNA, Untranslated | 2019 |
Targeting Inflammatory Mediators: An Anticancer Mechanism of Thymoquinone Action.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Benzoquinones; Humans; Immunotherapy; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Interleukins; Neoplasms; NF-kappa B; Tumor Necrosis Factor-alpha | 2021 |
Thymoquinone, an Active Compound of Nigella sativa: Role in Prevention and Treatment of Cancer.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Benzoquinones; Humans; Neoplasms; Nigella sativa; Plant Extracts; Plants, Medicinal; Signal Transduction | 2020 |
Thymoquinone-chemotherapeutic combinations: new regimen to combat cancer and cancer stem cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Hedgehog Proteins; Humans; Molecular Docking Simulation; Neoplasms; Neoplastic Stem Cells; Protein Interaction Domains and Motifs; Smoothened Receptor; Tankyrases; Wnt Proteins; Wnt Signaling Pathway | 2020 |
Targeting kinases with thymoquinone: a molecular approach to cancer therapeutics.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Humans; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors; Protein Kinases | 2020 |
Biological Role of AKT and Regulation of AKT Signaling Pathway by Thymoquinone: Perspectives in Cancer Therapeutics.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Humans; Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Benzoquinones; Cell Line, Tumor; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Endoplasmic Reticulum Chaperone BiP; Humans; Mice; Neoplasms; Rats | 2021 |
Nutritional Value and Preventive Role of
Topics: Animals; Anticarcinogenic Agents; Benzoquinones; Biomarkers; Clinical Studies as Topic; Disease Susceptibility; Drug Evaluation, Preclinical; Humans; Neoplasms; Nigella sativa; Nutritive Value; Plant Extracts; Signal Transduction; Structure-Activity Relationship | 2021 |
Thymoquinone Is a Multitarget Single Epidrug That Inhibits the UHRF1 Protein Complex.
Topics: Benzoquinones; Carcinogenesis; CCAAT-Enhancer-Binding Proteins; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Promoter Regions, Genetic; Signal Transduction; Ubiquitin-Protein Ligases | 2021 |
Thymoquinone: A small molecule from nature with high therapeutic potential.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Biological Availability; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiomyopathies; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Liver Neoplasms; Nanoparticle Drug Delivery System; Neoplasms; Nervous System Diseases | 2021 |
Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.
Topics: Animals; Benzoquinones; Humans; Neoplasms; Nigella sativa; Oils, Volatile; Seeds; Transcription Factors | 2018 |
Thymoquinone-based nanotechnology for cancer therapy: promises and challenges.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Humans; Nanoparticles; Nanotechnology; Neoplasms | 2018 |
Thymoquinone: A novel strategy to combat cancer: A review.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Benzoquinones; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Signal Transduction | 2018 |
Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy.
Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Humans; Neoplasms; Nigella sativa; Phytotherapy; Seeds | 2019 |
Thymoquinone: fifty years of success in the battle against cancer models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Disease Models, Animal; Humans; Neoplasms; Nigella sativa | 2014 |
Mechanistic perspectives on cancer chemoprevention/chemotherapeutic effects of thymoquinone.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Transformation, Neoplastic; Humans; Neoplasms; Neovascularization, Pathologic; Nigella sativa; Seeds; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Thymoquinone Anticancer Discovery: Possible Mechanisms.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Transformation, Neoplastic; Chemoprevention; Disease Models, Animal; Drug Discovery; Humans; Neoplasms; Nigella sativa; Signal Transduction | 2015 |
Spices for Prevention and Treatment of Cancers.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Benzodioxoles; Benzoquinones; Capsaicin; Capsicum; Cell Proliferation; Crocus; Curcuma; Curcumin; Garlic; Humans; Neoplasms; Nigella sativa; Phytotherapy; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Spices; Zingiber officinale | 2016 |
Review on molecular and therapeutic potential of thymoquinone in cancer.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Benzoquinones; Cell Cycle; Cell Proliferation; Humans; Neoplasms; NF-kappa B | 2010 |
Thymoquinone: potential cure for inflammatory disorders and cancer.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Humans; Inflammation; Neoplasms | 2012 |
Mitigation of obesity-promoted diseases by Nigella sativa and thymoquinone.
Topics: Antioxidants; Benzoquinones; Cardiovascular Diseases; Chemoradiotherapy, Adjuvant; Humans; Insulin Resistance; Neoplasms; Nigella sativa; Obesity; Plant Extracts; Weight Loss | 2012 |
Anticancer activities of Nigella sativa (black cumin).
Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Humans; Medicine, Traditional; Neoplasms; Nigella sativa; Phytotherapy; Plant Extracts; Plant Oils; Seeds | 2011 |
Quinones derived from plant secondary metabolites as anti-cancer agents.
Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Cell Survival; Humans; Naphthoquinones; Neoplasms; Plant Extracts | 2013 |
Thymoquinone: a promising anti-cancer drug from natural sources.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Cycle; Humans; Molecular Structure; Neoplasms; Plants, Medicinal; Tumor Suppressor Protein p53 | 2006 |
13 other study(ies) available for thymoquinone and Neoplasms
| Article | Year |
|---|---|
Thymoquinone and its derivatives against breast cancer with HER2 positive:
Topics: Antineoplastic Agents; Benzoquinones; Computer Simulation; Molecular Docking Simulation; Neoplasms; Pharmaceutical Preparations | 2021 |
Several inhibitors of the Plk1 Polo-Box Domain turn out to be non-specific protein alkylators.
Topics: Alkylation; Antineoplastic Agents; Benzoates; Benzoquinones; Cell Cycle Proteins; Glycine; Humans; Mitosis; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Quinones; Sulfones | 2017 |
Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis.
Topics: Animals; Apoptosis; Benzoquinones; Biphenyl Compounds; Blood Platelets; Caspase 3; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Humans; Mice; Neoplasms; Nitrophenols; Piperazines; Platelet Activation; Sulfonamides; Thrombocytopenia | 2017 |
Effects of thymoquinone on liver miRNAs and oxidative stress in Ehrlich acid mouse solid tumor model.
Topics: Animals; Antioxidants; Benzoquinones; Disease Models, Animal; Liver; Male; Mice, Inbred BALB C; MicroRNAs; Neoplasms; Oxidative Stress | 2018 |
Aqueous solubility and degradation kinetics of the phytochemical anticancer thymoquinone; probing the effects of solvents, pH and light.
Topics: Antineoplastic Agents; Benzoquinones; Drug Stability; Humans; Hydrogen-Ion Concentration; Kinetics; Light; Neoplasms; Phytochemicals; Temperature | 2014 |
Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial-mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis.
Topics: Benzoquinones; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; Male; Neoplasms; Phloroglucinol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction | 2016 |
Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways.
Topics: Animals; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Movement; Cell Proliferation; Endothelial Cells; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; Male; MAP Kinase Signaling System; Mice; Mice, SCID; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays | 2008 |
Combinatorial effects of thymoquinone on the anti-cancer activity of doxorubicin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Cell Line, Tumor; DNA Fragmentation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Membrane Potential, Mitochondrial; Neoplasms; Reactive Oxygen Species; RNA, Messenger | 2011 |
Cellular localisation of antitumoral 6-alkyl thymoquinones revealed by an alkyne-azide click reaction and the streptavidin-biotin system.
Topics: Alkynes; Antineoplastic Agents; Azides; Benzoquinones; Biotin; Cell Compartmentation; Cell Line, Tumor; Click Chemistry; Female; Fluorescence; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Staining and Labeling; Streptavidin | 2011 |
Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo.
Topics: Animals; Apoptosis; Benzoates; Benzoquinones; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Centrosome; Chromosomes, Human; Humans; M Phase Cell Cycle Checkpoints; Mice; Neoplasms; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Quinones; Xenograft Model Antitumor Assays | 2011 |
Synthesis of double mesoporous core-shell silica spheres with tunable core porosity and their drug release and cancer cell apoptosis properties.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Line, Tumor; Drug Delivery Systems; Humans; Ketoprofen; Microspheres; Neoplasms; Particle Size; Porosity; Silicon Dioxide | 2012 |
Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Movement; Cisplatin; Drug Synergism; Female; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Xenograft Model Antitumor Assays | 2013 |
The antitumor activity of thymoquinone and thymohydroquinone in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Fibroblasts; Male; Mice; Mice, Inbred Strains; Neoplasms; Thymol | 2006 |