thymoquinone has been researched along with Inflammation in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.08) | 29.6817 |
| 2010's | 25 (52.08) | 24.3611 |
| 2020's | 22 (45.83) | 2.80 |
| Authors | Studies |
|---|---|
| Akin, AT; Karabulut, D; Kaymak, E; Öztürk, E; Yakan, B | 2 |
| Goh, BH; Phua, CYH; Tang, YQ; Teoh, ZL; Yap, WH | 1 |
| Awad, A; Badr, AM; El-Bakly, WM; El-Demerdash, E; Medhet, M | 1 |
| Agrawal, Y; Goyal, SN; Nagoor Meeran, MF; Nakhate, KT; Ojha, S; Patil, CR; Rathod, S; Sherikar, A | 1 |
| Abdel Moneim, AE; Al Sberi, H; Al-Amer, O; Albarakati, AJA; Albrakati, A; Alghamdi, KS; Alharthi, F; Alsharif, KF; Althagafi, HA; Alzahrani, KJ; Amin, HK; Elhefny, MA; Fathalla, AS; Hassan, KE; Kassab, RB; Lokman, MS; Salama, B | 1 |
| Deng, S; Guo, W; Liu, D; Long, X; Lv, M; Yang, Q | 1 |
| Al-Amer, O; Albrakati, A; Algahtani, M; Alharthi, F; Alsharif, KF; Althagafi, HA; Amin, HK; Dahran, N; Dawood, SM; Ellethy, RA; Habotta, OA; Hijazy, HHA; Kassab, RB; Lokman, MS; Oyouni, AAA; Theyab, A | 1 |
| Abdel-Maqsoud, NMR; Alaaeldin, E; Aleem, MMAE; Aziz, NM; Kamel, MY; Mady, FM; Refaat, H; Saber, EA | 1 |
| Gao, L; Hu, L; Jiang, N; Jiang, R; Liu, X; Yao, H; Zhao, G; Zheng, W | 1 |
| Elahi, M; Ishikawa, M; Kuwahara, T; Nagao, T; Nakayama-Imaohji, H; Shibuya, K; Tada, A; Yagi, H; Yamasaki, H | 1 |
| Bi, A; Huang, D; Jia, H; Jiang, X; Li, J; Li, Q; Liu, Y; Mao, M; Xia, S | 1 |
| Dianat, M; Farbood, Y; Hajipour, S; Khorsandi, LS; Rashno, M; Sarkaki, A | 1 |
| Li, L; Lian, L; Liang, J; Wang, X | 1 |
| Kumar, D; Maurya, P; Mishra, N; Pal, RR; Raj, V; Rajpal, V; Saraf, SA; Singh, N; Singh, P; Singh, S; Tiwari, N | 1 |
| Almatroodi, SA; Alsahli, MA; Alzohairy, MA; Khan, AA; Rahmani, AH | 1 |
| Afrin, T; Alam, M; Choi, HJ; Dash, R; Hannan, MA; Haque, MN; Hossain, MT; Jahan, I; Khan, MK; Kim, B; Mitra, S; Mohibbullah, M; Moon, IS; Munni, YA; Oktaviani, DF; Rahman, MA; Rahman, MM; Rahman, MS; Sarker, PP; Sikder, MH; Sohag, AAM; Tahjib-Ul-Arif, M; Timalsina, B; Uddin, MJ | 1 |
| Elhadidy, WF; Farag, MM; Khalifa, AA; Rashad, RM | 1 |
| Abd Al Haleem, EN; Arafa, HMM; Hasan, WYS | 1 |
| Cordato, DJ; Fatima Shad, K; Soubra, W | 1 |
| Abu-Yousef, IA; Majdalawieh, AF; Yousef, SM | 1 |
| Akin, AT; Karabulut, D; Kaymak, E; Kuloğlu, N; Öztürk, E; Yakan, B | 1 |
| Asgharzadeh, F; Bargi, R; Beheshti, F; Hosseini, M; Khazaei, M; Sadeghnia, HR | 1 |
| Chen, Y; Feng, Y; Li, B; Luo, Q; Ren, Z; Shao, Y; Xie, Y; Zhu, L | 1 |
| Al-Gayyar, MM; El-Sherbiny, M; Elsherbiny, NM; Maysarah, NM | 1 |
| Farkhondeh, T; Hayati, F; Noorbakhsh, MF; Samarghandian, S; Shaterzadeh-Yazdi, H | 1 |
| Alam, MF; Anwer, T; Khan, G; Masmali, AUM; Qumayri, HM; Safhi, MM; Siddiqui, R | 1 |
| Ahmad, A; Alkharfy, KM; Jan, BL; Raish, M | 1 |
| Cobourne-Duval, MK; Mendonca, P; Soliman, KFA; Taka, E | 1 |
| Aslam, H; Irshad, S; Shabbir, A; Shahzad, M | 1 |
| Guo, L; Liu, H; Pei, Z; Sun, Y; Yang, G; Zhang, Y; Zhao, Y | 1 |
| Arjumand, S; Shabbir, A; Shahzad, M; Yousaf, MZ | 1 |
| Davarci, I; Karcioglu, M; Nacar, A; Rifaioglu, MM; Sefil, NK; Yonden, Z; Yuksel, R; Zorba, OU | 1 |
| Aruna, R; Geetha, A; Siva, GV; Suguna, P | 1 |
| Kim, SJ; Yu, SM | 1 |
| Arumugam, G; Ganesan, VS; Periyanayagam, S; Ravikumar, A | 1 |
| Aras, S; Armutcu, F; Aydin, B; Gerin, F; Sener, U; Turan, BC; Ustunsoy, S | 1 |
| Chaudhari, P; Jeengar, MK; Naidu, VG; Nemani, H; Ramavat, RN; Shrivastava, S; Thummuri, D | 1 |
| Chiragh, S; Faisal, R; Popalzai, AJ | 1 |
| Faisal, R; Jehangir, T; Shinwari, L | 1 |
| Jiang, YN; Li, N; Liu, H; Liu, HY | 1 |
| Abuawad, A; Cui, H; Kim, J; Mousa, SA; Muralidharan-Chari, V; Naeem, M | 1 |
| Kang, J; Kong, L; Ren, Y; Su, X; Yu, N | 1 |
| Benderdour, M; Fahmi, H; Fernandes, JC; Shi, Q; Silva, P; Vaillancourt, F | 1 |
| Kumar, AP; Sethi, G; Tan, KH; Woo, CC | 1 |
| Dumont, S; Hentsch, D; Kessler, P; Moreira-Tabaka, H; Muller, CD; Peluso, J; Reimund, JM; Vonesch, JL | 1 |
| Arikanoglu, Z; Evliyaoglu, O; Firat, U; Kapan, M; Onder, A; Taskesen, F; Tekin, R | 1 |
| Dreskin, SC; El Gazzar, M; El Mezayen, R; Marecki, JC; Nicolls, MR | 1 |
6 review(s) available for thymoquinone and Inflammation
| Article | Year |
|---|---|
Triangulating the pharmacological properties of thymoquinone in regulating reactive oxygen species, inflammation, and cancer: Therapeutic applications and mechanistic pathways.
Topics: Animals; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Clinical Trials as Topic; Humans; Inflammation; Inflammation Mediators; Neoplasms; Reactive Oxygen Species; Signal Transduction | 2021 |
Black Cumin (
Topics: Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Biological Availability; Cell Survival; Dietary Supplements; Drug Delivery Systems; Drug-Related Side Effects and Adverse Reactions; Energy Metabolism; Functional Food; Humans; Immunomodulation; Inflammation; Nigella sativa; Oxidative Stress; Phytotherapy; Plant Preparations | 2021 |
The role of thymoquinone, a major constituent of Nigella sativa, in the treatment of inflammatory and infectious diseases.
Topics: Animals; Benzoquinones; Communicable Diseases; Humans; Inflammation; Nigella sativa | 2021 |
Thymoquinone, a major constituent in Nigella sativa seeds, is a potential preventative and treatment option for atherosclerosis.
Topics: Animals; Atherosclerosis; Benzoquinones; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hyperlipidemias; Inflammation; Nigella sativa; Oxidative Stress; Seeds; Treatment Outcome | 2021 |
Immunomodulatory and Anti-inflammatory Effects of Thymoquinone.
Topics: Anti-Inflammatory Agents; Benzoquinones; Humans; Immunomodulation; Inflammation; Nigella sativa | 2018 |
Thymoquinone: potential cure for inflammatory disorders and cancer.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Humans; Inflammation; Neoplasms | 2012 |
42 other study(ies) available for thymoquinone and Inflammation
| Article | Year |
|---|---|
Therapeutic effects of thymoquinone in doxorubicin-induced hepatotoxicity via oxidative stress, inflammation and apoptosis.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Chemical and Drug Induced Liver Injury; Doxorubicin; Inflammation; Oxidative Stress; Rats; Rodent Diseases | 2021 |
Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression.
Topics: Animals; Apoptosis; Benzoquinones; Biomarkers; Cytochromes c; Gene Expression Regulation, Enzymologic; Inflammation; Isoproterenol; Matrix Metalloproteinase 9; Myocardial Infarction; Random Allocation; Rats; Rats, Wistar | 2022 |
Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation.
Topics: Animals; Benzoquinones; Cardiotonic Agents; Heart; Inflammation; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Myocardium; Oxidative Stress; Rats; Rats, Wistar | 2022 |
Thymoquinone alleviates doxorubicin induced acute kidney injury by decreasing endoplasmic reticulum stress, inflammation and apoptosis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Caspase 3; Doxorubicin; Endoplasmic Reticulum Stress; Inflammation; Interleukin-17; Olive Oil; Oxidants; Oxidative Stress; Rats; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2022 |
Silver Nanoparticles Enhance Oxidative Stress, Inflammation, and Apoptosis in Liver and Kidney Tissues: Potential Protective Role of Thymoquinone.
Topics: Animals; Antioxidants; Apoptosis; Benzoquinones; Inflammation; Kidney; Liver; Metal Nanoparticles; Oxidative Stress; Rats; Silver | 2023 |
Effect of thymoquinone on sepsis-induced cardiac damage
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Sepsis | 2022 |
Thymoquinone counteracts oxidative and inflammatory machinery in carrageenan-induced murine paw edema model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carrageenan; Edema; Inflammation; Mice; Nitric Oxide; Oxidative Stress; Tumor Necrosis Factor-alpha | 2023 |
Co-administration of Thymoquinone and Propolis in Liposomal Formulations as a Potential Approach for Treatment of Acetic Acid-Induced Ulcerative Colitis: Physiological and Histopathological Analysis.
Topics: Acetic Acid; Colitis; Colitis, Ulcerative; Humans; Inflammation; Liposomes; Propolis | 2023 |
Thymoquinone attenuates inflammation in C. Albicans keratitis by activating Nrf2/HO-1 signaling pathway and reducing fungal load.
Topics: Animals; Anti-Inflammatory Agents; Antifungal Agents; Candida albicans; Humans; Inflammation; Keratitis; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Signal Transduction | 2023 |
Effect of thymoquinone on Fusobacterium nucleatum‑associated biofilm and inflammation.
Topics: Actinomyces; Benzoquinones; Biofilms; Fusobacterium nucleatum; Gingiva; Humans; Inflammation; Microscopy, Confocal; Periodontitis; Plant Oils; THP-1 Cells; Thymol; Tumor Necrosis Factor-alpha | 2020 |
Thymoquinone ameliorates the PM2.5-induced lung injury in rats.
Topics: Animals; Apoptosis; Autophagy; Benzoquinones; Heme Oxygenase-1; Inflammation; Lung; Lung Injury; Male; NF-E2-Related Factor 2; Oxidative Stress; Particulate Matter; Rats; Rats, Wistar; Signal Transduction | 2020 |
The effects of thymoquinone on memory impairment and inflammation in rats with hepatic encephalopathy induced by thioacetamide.
Topics: Animals; Benzoquinones; Glutathione; Hepatic Encephalopathy; Hippocampus; Inflammation; Interleukin-10; Interleukin-1beta; Male; Memory; Memory Disorders; Oxidative Stress; Rats; Rats, Wistar; Thioacetamide; Tumor Necrosis Factor-alpha | 2021 |
Thymoquinone, extract from Nigella sativa seeds, protects human skin keratinocytes against UVA-irradiated oxidative stress, inflammation and mitochondrial dysfunction.
Topics: Apoptosis; Benzoquinones; Cell Line, Transformed; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; HaCaT Cells; Humans; Inflammation; Keratinocytes; Mitochondria; NF-E2-Related Factor 2; Nigella sativa; Oxidative Stress; Plant Extracts; Protective Agents; Reactive Oxygen Species; Seeds; Skin; Ultraviolet Rays | 2021 |
Synthesis of pH-sensitive crosslinked guar gum-g-poly(acrylic acid-co-acrylonitrile) for the delivery of thymoquinone against inflammation.
Topics: Antioxidants; Benzoquinones; Biocompatible Materials; Galactans; Humans; Hydrogen-Ion Concentration; Inflammation; Magnetic Resonance Spectroscopy; Mannans; Plant Gums; Spectroscopy, Fourier Transform Infrared | 2021 |
Protective Effects of Thymoquinone, an Active Compound of
Topics: Animals; Antioxidants; Benzo(a)pyrene; Benzoquinones; Cholesterol; DNA Fragmentation; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Lipids; Lung; Lung Injury; Male; Nigella sativa; Nitric Oxide; Oxidative Stress; Pulmonary Fibrosis; Rats; Treatment Outcome; Tumor Necrosis Factor-alpha | 2021 |
Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Benzoquinones; Cardiotonic Agents; Disease Progression; Dose-Response Relationship, Drug; Fibrosis; Inflammation; Isoproterenol; Male; Myocardial Infarction; Oxidative Stress; Rats | 2021 |
Therapeutic effects of thymoquinone or capsaicin on acrylamide-induced reproductive toxicity in rats mediated by their effect on oxidative stress, inflammation, and tight junction integrity.
Topics: Acrylamide; Animals; Benzoquinones; Capsaicin; Inflammation; Male; Occludin; Oxidative Stress; Rats; Tight Junctions | 2022 |
Thymoquinone has a neuroprotective effect against inflammation, oxidative stress, and endoplasmic reticulum stress in the brain cortex, medulla, and hippocampus due to doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Benzoquinones; Cerebral Cortex; Doxorubicin; Endoplasmic Reticulum Stress; Hippocampus; Inflammation; Medulla Oblongata; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar | 2021 |
The effects of thymoquinone on hippocampal cytokine level, brain oxidative stress status and memory deficits induced by lipopolysaccharide in rats.
Topics: Animals; Benzoquinones; Catalase; Cytokines; Hippocampus; Inflammation; Interleukin-6; Lipopolysaccharides; Male; Malondialdehyde; Maze Learning; Memory; Memory Disorders; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2017 |
Involvement of microRNA-146a in the Inflammatory Response of S tatus Epilepticus Rats.
Topics: Animals; Anticonvulsants; Benzoquinones; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Inflammation; Lithium Chloride; Male; MicroRNAs; Muscarinic Agonists; NF-kappa B; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2017 |
Renal protective effects of thymoquinone against sodium nitrite-induced chronic toxicity in rats: Impact on inflammation and apoptosis.
Topics: Animals; Apoptosis; Benzoquinones; Cytokines; Dose-Response Relationship, Drug; Food Preservatives; Inflammation; Inflammation Mediators; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Nitrite | 2017 |
Thymoquinone and fluoxetine alleviate depression via attenuating oxidative damage and inflammatory markers in type-2 diabetic rats.
Topics: Animals; Antioxidants; Behavior, Animal; Benzoquinones; Biomarkers; Cytokines; Depression; Diabetes Mellitus, Experimental; Drug Interactions; Fluoxetine; Frontal Lobe; Glutathione; Inflammation; Male; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2019 |
Thymoquinone reduces mortality and suppresses early acute inflammatory markers of sepsis in a mouse model.
Topics: Acute Disease; Animals; Benzoquinones; Biomarkers; C-Reactive Protein; Disease Models, Animal; Escherichia coli; Inflammation; Kaplan-Meier Estimate; Mice, Inbred BALB C; Proteoglycans; Sepsis; Survival Analysis; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2018 |
Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB pathway signaling targets in LPS/IFNγ -activated BV-2 microglia cells.
Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Cell Line; Cytokines; Gene Expression; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Microglia; Neuroprotective Agents; NF-kappa B; Signal Transduction | 2018 |
Immunomodulatory effect of thymoquinone on atopic dermatitis.
Topics: Animals; Benzoquinones; Cytokines; Dermatitis, Atopic; Ear; Female; Immunoglobulin E; Immunologic Factors; Inflammation; Mice, Inbred BALB C; Organ Size; RNA, Messenger | 2018 |
Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice.
Topics: Animals; Autophagy; Benzoquinones; Cytokines; Heart Diseases; Inflammation; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Protective Agents; Pyroptosis; Sepsis; Troponin T | 2019 |
Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzoquinones; Biomarkers; Disease Models, Animal; Down-Regulation; Inflammation; Interleukin-1beta; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
Antioxidative and anti-inflammatory effect of thymoquinone in an acute Pseudomonas prostatitis rat model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Catalase; Disease Models, Animal; Glutathione Peroxidase; Inflammation; Male; Malondialdehyde; Nitric Oxide; Prostatitis; Pseudomonas; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
Effect of thymoquinone on ethanol and high fat diet induced chronic pancreatitis--a dose response study in rats.
Topics: Animals; Antioxidants; Benzoquinones; Body Weight; Diet, High-Fat; Dose-Response Relationship, Drug; Ethanol; Glutathione; Inflammation; Interleukin-18; Interleukin-1beta; Lipase; Lipid Peroxides; Male; Oxidative Stress; Pancreatitis, Chronic; Peroxidase; Rats; Rats, Wistar | 2013 |
The thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and PI3K pathways in rabbit articular chondrocytes.
Topics: Animals; Benzoquinones; Cartilage, Articular; Cell Dedifferentiation; Cells, Cultured; Chondrocytes; Inflammation; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Rabbits; Reactive Oxygen Species | 2015 |
Thymoquinone ameliorates NLRP3-mediated inflammation in the pancreas of albino Wistar rats fed ethanol and high-fat diet.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Benzoquinones; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cytokines; Diet, High-Fat; Disease Models, Animal; Ethanol; Inflammasomes; Inflammation; Inflammation Mediators; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pancreatitis; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation | 2015 |
Effects of sodium arsenite on the some laboratory signs and therapeutic role of thymoquinone in the rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arsenites; Benzoquinones; Cytoprotection; Inflammation; Liver; Male; Models, Animal; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Sodium Compounds | 2015 |
Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK Signalling.
Topics: 3T3 Cells; Animals; Benzoquinones; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteolysis; Oxidative Stress; Phosphorylation; RANK Ligand; RAW 264.7 Cells | 2015 |
Anti inflammatory effect of thymoquinone in comparison with methotrexate on pristane induced arthritis in rats.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzoquinones; Body Weight; Female; Foot Joints; Immunosuppressive Agents; Inflammation; Leukocyte Count; Methotrexate; Random Allocation; Rats; Rats, Sprague-Dawley; Terpenes | 2015 |
Comparison of the Therapeutic Effects of Thymoquinone and Methotrexate on Renal Injury in Pristane Induced Arthritis in Rats.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzoquinones; Creatinine; Female; Humans; Inflammation; Kidney; Leukocyte Count; Methotrexate; Random Allocation; Rats; Rats, Sprague-Dawley; Terpenes; Urea | 2015 |
Protective effect of thymoquinone improves cardiovascular function, and attenuates oxidative stress, inflammation and apoptosis by mediating the PI3K/Akt pathway in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzoquinones; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drug Evaluation, Preclinical; Inflammation; Male; Malondialdehyde; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha | 2016 |
Thymoquinone Modulates Blood Coagulation in Vitro via Its Effects on Inflammatory and Coagulation Pathways.
Topics: Anticoagulants; Benzoquinones; Blood Coagulation; Cell Line, Tumor; Factor Xa; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Oils, Volatile; Partial Thromboplastin Time; Seeds; Thrombelastography; Thromboplastin; Thrombosis; Tumor Necrosis Factor-alpha | 2016 |
Thymoquinone inhibits inflammation, neoangiogenesis and vascular remodeling in asthma mice.
Topics: Airway Remodeling; Animals; Asthma; Benzoquinones; Disease Models, Animal; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Interleukin-4; Interleukin-5; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Nerve Tissue Proteins; Nigella sativa; Oncogene Protein v-akt; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis.
Topics: Aged; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzoquinones; Cell Proliferation; Cyclooxygenase 2; Female; Fibroblasts; Humans; Inflammation; Interleukin-1beta; Male; NF-kappa B; Rats; Signal Transduction; Synovial Fluid; Tumor Necrosis Factor-alpha | 2011 |
Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Benzoquinones; Cell Line; Cell Membrane; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Hydroxamic Acids; Inflammation; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Microscopy, Confocal; Monocytes; Pentacyclic Triterpenes; Peptide Hydrolases; Recombinant Proteins; Sulfonamides; Triterpenes; Tumor Necrosis Factor-alpha | 2012 |
Thymoquinone ameliorates bacterial translocation and inflammatory response in rats with intestinal obstruction.
Topics: Animals; Anti-Bacterial Agents; Bacterial Translocation; Benzoquinones; Hepatitis; Histocytochemistry; Ileum; Inflammation; Intestinal Mucosa; Intestinal Obstruction; Lymph Nodes; Rats; Rats, Wistar; Statistics, Nonparametric | 2012 |
Downregulation of leukotriene biosynthesis by thymoquinone attenuates airway inflammation in a mouse model of allergic asthma.
Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Benzoquinones; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Down-Regulation; Female; Hypersensitivity; Inflammation; Leukotrienes; Lung; Male; Mice; Mice, Inbred BALB C; Nigella sativa | 2006 |