Page last updated: 2024-08-21

thymoquinone and Cancer of Liver

thymoquinone has been researched along with Cancer of Liver in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (37.50)24.3611
2020's10 (62.50)2.80

Authors

AuthorsStudies
Abualnaja, KO; Al-Babili, S; Al-Malki, AL; Alhosin, M; Asami, T; Choudhry, H; Halwani, MA; Hasan, MN; Kumosani, TA; Moselhy, SS; Omran, Z; Razvi, SS; Zamzami, MA1
Badary, OA; Fahim, SA; Ibrahim, S; Tadros, SA1
Abdualmjid, RJ; Sergi, CM1
Abdelwahed, FM; Attia, YM; Badary, OA; Fahim, SA; Ibrahim, S; Maurice, NW; Tadros, SA1
Babalghith, AO; El-Far, AH; El-Sewedy, T; El-Shehawy, AA; Elmetwalli, A; Gaber, M; Mahmoud, MA; Mohany, H; Mosallam, SAE; Salama, AF1
Abd-Elaziz, A; Khalil, H; Salah, A; Sleem, R1
Afşar, E; Aslan, M; Çeker, T; Kırımlıoglu, E; Yılmaz, Ç1
Anwer, R; Bashir, AO; Eissa, LA; El-Mesery, ME1
Liu, M; Wu, T; Xi, M; Xu, G; Yu, J; Zhang, R; Zheng, P1
Gao, J; Huang, CY; Kang, ZF; Ting, WJ; Weng, YJ; Zhang, B1
Kapoor, VK; Malik, S; Negi, P; Singh, A1
Bardakci, O; Gozeneli, O; Guldur, ME; Gunes, AE; Taskin, A; Tatli, F; Yilmaz, M1
Ebeid, EM; El-Ashmawy, NE; Khedr, EG; Mosalam, EM; Salem, ML; Zidan, AA1
Abd-Allah, AR; Abdel-Hamied, HE; Alzahrani, AZ; Ashour, AE; Attia, SM; Bakheet, SA; Jamal, S; Korashy, HM; Rishi, AK; Saquib, Q1
Abdelaziz, A; Ashmawy, AM; Badary, O; ElKhoely, A; Hafez, HF; Mostafa, A; Shouman, SA1
Cheng, Y; He, S; Ke, X; Liu, Y; Lu, G; Lu, X; Meltzer, SJ; Ren, M; Song, JH; Sun, Z; Wang, Z; Xu, Z; Zhang, D; Zhao, Y1

Reviews

2 review(s) available for thymoquinone and Cancer of Liver

ArticleYear
Mitochondrial Dysfunction and Induction of Apoptosis in Hepatocellular Carcinoma and Cholangiocarcinoma Cell Lines by Thymoquinone.
    International journal of molecular sciences, 2022, Nov-24, Volume: 23, Issue:23

    Topics: Animals; Apoptosis; Benzoquinones; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholangiocarcinoma; Liver Neoplasms; Mitochondria

2022
Thymoquinone: A small molecule from nature with high therapeutic potential.
    Drug discovery today, 2021, Volume: 26, Issue:11

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Biological Availability; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiomyopathies; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Liver Neoplasms; Nanoparticle Drug Delivery System; Neoplasms; Nervous System Diseases

2021

Other Studies

14 other study(ies) available for thymoquinone and Cancer of Liver

ArticleYear
Synthetic strigolactone analogues reveal anti-cancer activities on hepatocellular carcinoma cells.
    Bioorganic & medicinal chemistry letters, 2018, 04-01, Volume: 28, Issue:6

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Lactones; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship

2018
Suppressive effects of thymoquinone on the initiation stage of diethylnitrosamine hepatocarcinogenesis in rats.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:8

    Topics: Animals; Antioxidants; Benzoquinones; Carcinoma, Hepatocellular; Diethylnitrosamine; Glutathione; Liver; Liver Neoplasms; Male; Oxidative Stress; Rats; Rats, Wistar

2022
Thymoquinone Suppresses Angiogenesis in DEN-Induced Hepatocellular Carcinoma by Targeting miR-1-3p.
    International journal of molecular sciences, 2022, Dec-14, Volume: 23, Issue:24

    Topics: Animals; Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; MicroRNAs; Rats; Vascular Endothelial Growth Factor A

2022
Thymoquinone, piperine, and sorafenib combinations attenuate liver and breast cancers progression: epigenetic and molecular docking approaches.
    BMC complementary medicine and therapies, 2023, Mar-04, Volume: 23, Issue:1

    Topics: Epigenesis, Genetic; Humans; Liver Neoplasms; MicroRNAs; Molecular Docking Simulation; Sorafenib

2023
Regulation of NF-κB Expression by Thymoquinone; A Role in Regulating Pro-Inflammatory Cytokines and Programmed Cell Death in Hepatic Cancer Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2023, Nov-01, Volume: 24, Issue:11

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line; Cytokines; GTPase-Activating Proteins; Humans; Liver Neoplasms; NF-kappa B; Tumor Suppressor Proteins

2023
Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress.
    Nutrition and cancer, 2021, Volume: 73, Issue:3

    Topics: Apoptosis; Benzoquinones; Ceramides; Chromatography, Liquid; Endoplasmic Reticulum Chaperone BiP; Humans; Liver Neoplasms; MCF-7 Cells; Tandem Mass Spectrometry

2021
Thymoquinone potentiates miR-16 and miR-375 expressions in hepatocellular carcinoma.
    Life sciences, 2020, Aug-01, Volume: 254

    Topics: Apoptosis; Benzoquinones; Carcinoma, Hepatocellular; Case-Control Studies; Caspase 3; Cell Line, Tumor; Doxorubicin; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; MicroRNAs; Middle Aged; Proto-Oncogene Proteins c-bcl-2

2020
Thymoquinone sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis via oxidative DNA damage.
    DNA repair, 2021, Volume: 103

    Topics: Apoptosis; Benzoquinones; Carcinoma, Hepatocellular; DNA; DNA Damage; Hep G2 Cells; Humans; Liver Neoplasms; Oxidative Stress; TNF-Related Apoptosis-Inducing Ligand

2021
Erk phosphorylation reduces the thymoquinone toxicity in human hepatocarcinoma.
    Environmental toxicology, 2021, Volume: 36, Issue:10

    Topics: Animals; Apoptosis; Benzoquinones; Carcinoma, Hepatocellular; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Liver Neoplasms; Mice; Mice, Nude; Phosphorylation

2021
Effects of thymoquinone and curcumin on the regeneration of rat livers subject to 70% hepatectomy.
    Acta cirurgica brasileira, 2018, Volume: 33, Issue:2

    Topics: Animals; Antineoplastic Agents; Antioxidants; Arginase; Benzoquinones; Biomarkers; Cell Proliferation; Ceruloplasmin; Curcumin; Female; Hepatectomy; Ki-67 Antigen; Liver; Liver Neoplasms; Liver Regeneration; Liver Transplantation; Nitric Oxide; Rats; Rats, Wistar; Tissue Plasminogen Activator

2018
Loading of doxorubicin and thymoquinone with F2 gel nanofibers improves the antitumor activity and ameliorates doxorubicin-associated nephrotoxicity.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Acetylglucosamine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Benzoquinones; Biomarkers; Caspase 3; Cell Survival; Doxorubicin; Drug Delivery Systems; Female; Hep G2 Cells; Humans; Kidney; Liver Neoplasms; MCF-7 Cells; Mice; Nanofibers; Neoplasms, Experimental; Oxidative Stress; Particle Size

2018
Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative stress and apoptosis.
    Molecular and cellular biochemistry, 2014, Volume: 389, Issue:1-2

    Topics: Apoptosis; bcl-X Protein; Benzoquinones; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Interleukin-8; Liver Neoplasms; M Phase Cell Cycle Checkpoints; NF-kappa B; Oxidative Stress; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand

2014
Chemopreventive and therapeutic potentials of thymoquinone in HepG2 cells: mechanistic perspectives.
    Journal of natural medicines, 2015, Volume: 69, Issue:3

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Cycle; Cell Line, Tumor; Cell Survival; Chemoprevention; Cytochrome P-450 CYP1A1; Drug Screening Assays, Antitumor; Glutathione; Glutathione Transferase; HCT116 Cells; HeLa Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Vascular Endothelial Growth Factor A

2015
TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Benzoquinones; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Receptor, Notch1; Signal Transduction; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2015