Page last updated: 2024-08-21

thymoquinone and Cancer of Colon

thymoquinone has been researched along with Cancer of Colon in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's10 (66.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Arvizu-Espinosa, MG; Estrada-Meza, C; Osorio-Pérez, SM; Paul, S; Ruiz-Manriquez, LM; Sharma, A; Srivastava, A1
Awad, GAS; Metwally, AA; Nasr, M; Ramzy, L1
Kapoor, VK; Malik, S; Negi, P; Singh, A1
Choi, BY; Chun, KS; Jeong, CH; Kundu, J; Kundu, JK1
Chen, LM; Chen, MC; Ho, TJ; Hsieh, DJ; Hsu, HH; Huang, CY; Kuo, WW; Lee, NH; Lin, YM; Tu, CC1
Agbaria, R; Ben-Shabat, S; Dahan, A; Gabarin, A1
Chen, MC; Chen, RJ; Ho, TJ; Hsu, HH; Huang, CY; Kuo, WW; Lee, NH; Lin, YM; Tu, CC; Viswanadha, VP1
Ahmad, J; El-Shemi, AG; Idris, S; Kensara, OA; Mohamed, AM; Refaat, B1
El-Baba, C; Fatfat, M; Fröhlich, T; Gali-Muhtasib, H; Hofmeister, E; Mederer, S; Muenzner, JK; Ndreshkjana, B; Reiter, C; Schneider-Stock, R; Tsogoeva, SB1
Chen, MC; Day, CH; Hsu, HH; Huang, CY; Kuo, WW; Li, SY; Lin, YM; Padma, VV; Shih, HN; Tu, CC1
Chatila, M; El-Najjar, N; Gali-Muhtasib, H; Gandesiri, M; Moukadem, H; Ocker, M; Schneider-Stock, R; Vuorela, H1
Grayaa, R; Hammami, M; Harzallah, HJ; Kharoubi, W; Maaloul, A; Mahjoub, T1
Almawi, WY; Ben-Hadj-Khalifa, S; Houas, Z; Jrah-Harzallah, H; Maaloul, A; Mahjoub, T1
Benghuzzi, H; May, M; Norwood, AA; Tan, M; Tucci, M1
Benghuzzi, H; Norwood, AA; Tucci, M1

Reviews

1 review(s) available for thymoquinone and Cancer of Colon

ArticleYear
Thymoquinone: A small molecule from nature with high therapeutic potential.
    Drug discovery today, 2021, Volume: 26, Issue:11

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Biological Availability; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiomyopathies; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Liver Neoplasms; Nanoparticle Drug Delivery System; Neoplasms; Nervous System Diseases

2021

Other Studies

14 other study(ies) available for thymoquinone and Cancer of Colon

ArticleYear
Thymoquinone Potentially Modulates the Expression of Key Onco- and Tumor Suppressor miRNAs in Prostate and Colon Cancer Cell Lines: Insights from PC3 and HCT-15 Cells.
    Genes, 2023, 08-30, Volume: 14, Issue:9

    Topics: Cell Line, Tumor; Colonic Neoplasms; Humans; Male; MicroRNAs; PC-3 Cells; Prostate; Prostatic Neoplasms

2023
Novel thymoquinone lipidic core nanocapsules with anisamide-polymethacrylate shell for colon cancer cells overexpressing sigma receptors.
    Scientific reports, 2020, 07-03, Volume: 10, Issue:1

    Topics: Benzamides; Benzoquinones; Caco-2 Cells; Cell Proliferation; Cell Survival; Colonic Neoplasms; Delayed-Action Preparations; HCT116 Cells; HT29 Cells; Humans; Nanocapsules; Particle Size; Polymethacrylic Acids; Receptors, sigma

2020
Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.
    Oncology reports, 2014, Volume: 32, Issue:2

    Topics: Apoptosis; Benzoquinones; Cell Proliferation; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; ErbB Receptors; HCT116 Cells; Humans; Janus Kinase 2; Phosphorylation; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor

2014
Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and p38.
    Journal of agricultural and food chemistry, 2015, Feb-11, Volume: 63, Issue:5

    Topics: Apoptosis; Autophagy; Benzoquinones; Caspases; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; JNK Mitogen-Activated Protein Kinases; Mitochondria; Nigella sativa; p38 Mitogen-Activated Protein Kinases; Plant Extracts

2015
Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Stability; Gene Expression Regulation, Neoplastic; Hodgkin Disease; Hot Temperature; Mice; NF-kappa B; Nigella sativa; Phytotherapy; Plant Extracts; Plant Oils; Plants, Medicinal; Seeds; Time Factors; Transcription, Genetic; Transfection

2015
Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.
    Environmental toxicology, 2017, Volume: 32, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Camptothecin; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Humans; Irinotecan; JNK Mitogen-Activated Protein Kinases; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Transcription Factor RelA

2017
Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Anticarcinogenic Agents; Benzoquinones; Carcinogenesis; Cell Proliferation; Colonic Neoplasms; Fluorouracil; Male; Rats, Wistar

2016
Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer.
    ChemMedChem, 2017, 02-03, Volume: 12, Issue:3

    Topics: Antineoplastic Agents; Artemisinins; Benzoquinones; Cell Survival; Colonic Neoplasms; HCT116 Cells; Histones; HT29 Cells; Humans; Reactive Oxygen Species

2017
Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.
    World journal of gastroenterology, 2017, Feb-21, Volume: 23, Issue:7

    Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Benzoquinones; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Phytochemicals; Signal Transduction

2017
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
    Apoptosis : an international journal on programmed cell death, 2010, Volume: 15, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Oxidative Stress; Reactive Oxygen Species

2010
Thymoquinone, the Nigella sativa bioactive compound, prevents circulatory oxidative stress caused by 1,2-dimethylhydrazine in erythrocyte during colon postinitiation carcinogenesis.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: 1,2-Dimethylhydrazine; Animals; Benzoquinones; Catalase; Cell Transformation, Neoplastic; Colonic Neoplasms; Erythrocytes; Glutathione Peroxidase; Hematocrit; Hemoglobins; Lipid Peroxidation; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase

2012
Effect of thymoquinone on 1,2-dimethyl-hydrazine-induced oxidative stress during initiation and promotion of colon carcinogenesis.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:5

    Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Benzoquinones; Body Weight; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Drug Evaluation, Preclinical; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2013
Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.
    Biomedical sciences instrumentation, 2006, Volume: 42

    Topics: Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Feasibility Studies; Fluorouracil; Plant Extracts; Tea; Treatment Outcome

2006
A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and thymoquinone, delivered by sustained drug delivery on colon cancer cells.
    Biomedical sciences instrumentation, 2007, Volume: 43

    Topics: Adenocarcinoma; Antineoplastic Agents; Benzoquinones; Catechin; Cell Proliferation; Cell Survival; Colonic Neoplasms; Delayed-Action Preparations; Dose-Response Relationship, Drug; Fluorouracil; Humans; Phytotherapy; Plant Extracts; Treatment Outcome; Tumor Cells, Cultured

2007