Page last updated: 2024-08-21

thymoquinone and Breast Neoplasms

thymoquinone has been researched along with Breast Neoplasms in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	21 (50.00)	24.3611
2020's	21 (50.00)	2.80

Authors

Authors	Studies
Hamid, SBS; Kaus, NHM; Noor, NS; Szewczuk, MR	1
Abd El Samea, GG; Abd El-Salam, NM; Abd-Rabou, AA; Abdalla, MS; Sharada, HMI	1
Fu, J; Imani, S; Liu, S; Lu, T; Shasaltaneh, MD; Zhou, J	1
Gupta, P; Kohli, K; Neupane, YR; Parvez, S; Sultana, Y	1
Aldarmahi, NA; Alkhattabi, NA; Alshaibi, HF; Alsufiani, HM; Tarbiah, NI	1
Al-Masum, A; Kazi, M; Khan, JH; Khan, MA; Shariare, MH; Uddin, J	1
Bidmeshkipour, A; Hajmomeni, P; Sisakhtnezhad, S	1
Alsrhani, A; Althobiti, MM; Alzahrani, B; Alzerwi, NAN; Elderdery, AY; Elkhalifa, AME; Idrees, B; Kumar, SS; Mok, PL; Rayzah, M	1
Baghini, SS; Chopani, A; Darroudi, M; Farkhondeh, T; Kabiri, M; Karami, MH; Kolour, J; Mardasi, M; Moulavi, P; Parvin, MA; Samarghandian, S; Sayyahi, Z; Shabani, H; Soghala, S	1
Ahmad, FJ; Ahmad, I; Akhter, S; Alam Rizvi, MM; Hafeez, Z; Jain, GK; Zafar, S	1
Ahmad, FJ; Akhter, S; Garg, N; Kumar Jain, G; Selvapandiyan, A; Zafar, S	1
Ajabnoor, GM; Al-Abd, AM; Alamoudi, AA; Bashmail, HA; Hegazy, GA; Noorwali, A	1
Ibiyeye, KM; Zuki, ABZ	1
Ergül, E; Korak, T; Sazci, A	1
Adhikary, A; Basu, A; Bhattacharjee, M; Das, S; Ghosh, A; Ghosh, S; Sarker, S; Upadhyay, P	1
Alkhatib, MH; Bawadud, RS; Gashlan, HM	1
Alwattar, JK; Chouaib, R; Gali-Muhtasib, H; Mehanna, MM; Sarieddine, R	1
Akbarzadeh, M; Bazmani, A; Haiaty, S; Mostafazadeh, M; Nikanfar, S; Nouri, M; Rahbarghazi, R; Rashidi, MR; Zibaei, Z	1
Abd-Rabou, AA; Abdalla, MS; Abdel Salam, NM; El Samea, GGA; Sharada, HM	1
Kapoor, VK; Malik, S; Negi, P; Singh, A	1
Cheng, J; Fu, J; Fu, S; Imani, S; Khan, MA; Tania, M; Wei, C; Xiao, X; Yang, L; Zhang, X	1
Basheti, IA; Odeh, LH; Talib, WH	1
Abd Rahman, N; Abdullah, R; Foo, JB; How, CW; Mustapha, NM; Ng, WK; Ong, YS; Saiful Yazan, L; Sapuan, S; Tor, YS; Zakarial Ansar, FH	1
Bulbake, U; Khan, W; Kommineni, N; Saka, R	1
Ahmad, R; Hamid, S; Kaus, NHM	1
Arumugamand, P; Kumar, BS; Ragunathan, PP; Raj, SK; Sundaravadivelu, S	1
Aumeeruddy, MZ; Mahomoodally, MF	1
Aldebasi, YH; Alsuhaibani, SA; Khan, A; Khan, MA	1
Adeli-Sardou, M; Barani, M; Mirzaei, M; Torkzadeh-Mahani, M	1
Azab, B; Das, S; Das, SK; Emdad, L; Fisher, PB; Kumar, BN; Mandal, M; Rajput, S; Santhekadur, PK; Sarkar, D; Sarkar, S	1
Dey, KK; Kumar, BN; Mandal, M; Pal, I; Parekh, A; Rajput, S	1
Hsu, A; Kumar, AP; Sethi, G; Tan, KH; Woo, CC	1
Banik, P; Kumar, BN; Mandal, M; Parida, S; Rajput, S	1
Adhikary, A; Ahir, M; Bhattacharya, S; Chattopadhyay, D; Chattopadhyay, S; Das, T; Ghosh, S; Mazumdar, M; Mukherjee, S; Patra, P	1
Cheng, J; Fu, J; Fu, S; Khan, MA; Mei, Z; Tania, M; Wei, C; Xu, J	1
Bharti, R; Dey, G; Fisher, PB; Konar, S; Kumar, BN; Mandal, M; Mazumdar, A; Pathak, A; Puvvada, N; Rajput, S; Sarkar, S	1
Deb, M; Kar, S; Parbin, S; Patra, SK; Pradhan, N; Rath, SK; Sengupta, D; Shilpi, A	1
Arafa, el-SA; Barakat, BM; El-Mahdy, MA; Racoma, I; Shah, ZI; Wani, AA; Wani, G; Zhu, Q	1
Jagtap, AG; Kumar, A; Mishra, KP; Pandey, BN; Velho-Pereira, R	1
Gee, V; Kumar, AP; Loo, SY; Sethi, G; Tan, KH; Woo, CC; Yap, CW	1
Doucette, CD; Hoskin, DW; Sutton, KM	1
Abu-Dahab, R; Al Bawab, A; Ismail, SI; Mahmoud, IS; Odeh, F	1

Reviews

4 review(s) available for thymoquinone and Breast Neoplasms

Article	Year
Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 165 Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Breast Neoplasms; Female; Humans; Nigella sativa	2023
Nigella sativa and Cancer: A Review Focusing on Breast Cancer, Inhibition of Metastasis and Enhancement of Natural Killer Cell Cytotoxicity. Current pharmaceutical biotechnology, 2020, Volume: 21, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Cell Survival; Female; Humans; Killer Cells, Natural; Neoplasm Metastasis; Nigella sativa; Plant Extracts; Plants, Medicinal; Seeds; Signal Transduction	2020
Thymoquinone: A small molecule from nature with high therapeutic potential. Drug discovery today, 2021, Volume: 26, Issue:11 Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Benzoquinones; Biological Availability; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiomyopathies; Colonic Neoplasms; Diabetes Mellitus, Type 2; Humans; Liver Neoplasms; Nanoparticle Drug Delivery System; Neoplasms; Nervous System Diseases	2021
Combating breast cancer using combination therapy with 3 phytochemicals: Piperine, sulforaphane, and thymoquinone. Cancer, 2019, 05-15, Volume: 125, Issue:10 Topics: Alkaloids; Antineoplastic Agents; Benzodioxoles; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; In Vitro Techniques; Isothiocyanates; Patient Selection; Phytochemicals; Phytotherapy; Piperidines; Polyunsaturated Alkamides; Radiotherapy, Adjuvant; Sensitivity and Specificity; Sulfoxides	2019

Other Studies

38 other study(ies) available for thymoquinone and Breast Neoplasms

Article	Year
Formulation, Characterization and Cytotoxicity Effects of Novel Thymoquinone-PLGA-PF68 Nanoparticles. International journal of molecular sciences, 2021, Aug-30, Volume: 22, Issue:17 Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Drug Compounding; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Nanoparticles; Paclitaxel; Poloxamer; Polylactic Acid-Polyglycolic Acid Copolymer	2021
Thymoquinone Crosstalks with DR5 to Sensitize TRAIL Resistance and Stimulate ROS-Mediated Cancer Apoptosis. Asian Pacific journal of cancer prevention : APJCP, 2021, Sep-01, Volume: 22, Issue:9 Topics: Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand	2021
PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway. Molecular biology reports, 2022, Volume: 49, Issue:3 Topics: Benzoquinones; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Female; Humans; Mutation; Phosphatidylinositol 3-Kinases; Prospective Studies; Proto-Oncogene Proteins c-akt	2022
Combinatorial Chemosensitive Nanomedicine Approach for the Treatment of Breast Cancer. Current molecular medicine, 2023, Volume: 23, Issue:9 Topics: Aromatase Inhibitors; Benzoquinones; Breast Neoplasms; Female; Humans; Nanomedicine	2023
Studying the Anticancer Effects of Thymoquinone on Breast Cancer Cells through Natural Killer Cell Activity. BioMed research international, 2022, Volume: 2022 Topics: Benzoquinones; Breast Neoplasms; Female; Granzymes; Humans; Interferon-alpha; Killer Cells, Natural; Nigella sativa; Perforin	2022
Development of Stable Liposomal Drug Delivery System of Thymoquinone and Its In Vitro Anticancer Studies Using Breast Cancer and Cervical Cancer Cell Lines. Molecules (Basel, Switzerland), 2022, Oct-10, Volume: 27, Issue:19 Topics: Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Liposomes; Particle Size; Phospholipids; Uterine Cervical Neoplasms	2022
Thymoquinone-treated mouse mesenchymal stem cells-derived conditioned medium inhibits human breast cancer cells in vitro. Chemico-biological interactions, 2023, Jan-05, Volume: 369 Topics: Animals; Breast Neoplasms; Cell Proliferation; Culture Media, Conditioned; Female; Humans; Mesenchymal Stem Cells; Mice; Necrosis; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species	2023
Sodium alginate encapsulated iron oxide decorated with thymoquinone nanocomposite induces apoptosis in human breast cancer cells via PI3K-Akt-mTOR pathway. International journal of biological macromolecules, 2023, Jul-31, Volume: 244 Topics: Alginates; Annexins; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Spectroscopy, Fourier Transform Infrared; TOR Serine-Threonine Kinases	2023
Improved chemotherapeutic efficacy against resistant human breast cancer cells with co-delivery of Docetaxel and Thymoquinone by Chitosan grafted lipid nanocapsules: Formulation optimization, in vitro and in vivo studies. Colloids and surfaces. B, Biointerfaces, 2020, Volume: 186 Topics: Animals; Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Docetaxel; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Screening Assays, Antitumor; Female; Humans; Lipids; MCF-7 Cells; Nanocapsules; Neovascularization, Pathologic; Rats; Structure-Activity Relationship	2020
Co-encapsulation of docetaxel and thymoquinone in mPEG-DSPE-vitamin E TPGS-lipid nanocapsules for breast cancer therapy: Formulation optimization and implications on cellular and in vivo toxicity. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 148 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanocapsules; Phosphatidylethanolamines; Polyethylene Glycols; Triple Negative Breast Neoplasms; Vitamin E	2020
Thymoquinone Enhances Paclitaxel Anti-Breast Cancer Activity via Inhibiting Tumor-Associated Stem Cells Despite Apparent Mathematical Antagonism. Molecules (Basel, Switzerland), 2020, Jan-20, Volume: 25, Issue:2 Topics: Benzoquinones; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; MCF-7 Cells; Neoplastic Stem Cells; Nuclear Proteins; Paclitaxel; Snail Family Transcription Factors; Twist-Related Protein 1	2020
Cockle Shell-Derived Aragonite CaCO International journal of molecular sciences, 2020, Mar-10, Volume: 21, Issue:5 Topics: Aldehyde Dehydrogenase; Animal Shells; Animals; Benzoquinones; Breast Neoplasms; Calcium Carbonate; Cardiidae; CD24 Antigen; Cell Line, Tumor; Doxorubicin; Female; Humans; Hyaluronan Receptors; Nanoparticles; Neoplastic Stem Cells; Spheroids, Cellular	2020
Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer. Biochimica et biophysica acta. General subjects, 2020, Volume: 1864, Issue:11 Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Movement; Cell Proliferation; Drug Synergism; Emodin; Female; Humans; MCF-7 Cells; Neoplastic Stem Cells; Protein Kinase Inhibitors	2020
Incorporation of docetaxel and thymoquinone in borage nanoemulsion potentiates their antineoplastic activity in breast cancer cells. Scientific reports, 2020, 10-22, Volume: 10, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Borago; Breast Neoplasms; Cell Proliferation; Docetaxel; Drug Delivery Systems; Emulsions; Female; Humans; Nanoparticles; Tumor Cells, Cultured	2020
Anticancer Activity of Thymoquinone Cubic Phase Nanoparticles Against Human Breast Cancer: Formulation, Cytotoxicity and Subcellular Localization. International journal of nanomedicine, 2020, Volume: 15 Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Hemolysis; Humans; MCF-7 Cells; Nanoparticles; Particle Size	2020
Thymoquinone inhibited vasculogenic capacity and promoted mesenchymal-epithelial transition of human breast cancer stem cells. BMC complementary medicine and therapies, 2021, Mar-04, Volume: 21, Issue:1 Topics: Benzoquinones; Breast Neoplasms; Cell Proliferation; Cell Survival; Epithelial-Mesenchymal Transition; Female; Humans; Neoplastic Stem Cells; Phosphoinositide-3 Kinase Inhibitors; Wnt3A Protein	2021
Combination Therapy of TRAIL and Thymoquinone Induce Breast Cancer Cell Cytotoxicity-Mediated Apoptosis and Cell Cycle Arrest. Asian Pacific journal of cancer prevention : APJCP, 2021, May-01, Volume: 22, Issue:5 Topics: Apoptosis; Benzoquinones; Breast Neoplasms; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Combined Modality Therapy; Female; Humans; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured	2021
MicroRNA-34a targets epithelial to mesenchymal transition-inducing transcription factors (EMT-TFs) and inhibits breast cancer cell migration and invasion. Oncotarget, 2017, Mar-28, Volume: 8, Issue:13 Topics: Adult; Aged; Antineoplastic Agents; Benzoquinones; Blotting, Western; Breast Neoplasms; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Nuclear Proteins; Real-Time Polymerase Chain Reaction; Receptor, Notch1; Transcription Factors; Twist-Related Protein 1; Zinc Finger E-box-Binding Homeobox 1	2017
Synergistic effect of thymoquinone and melatonin against breast cancer implanted in mice. Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement Topics: Animals; Antioxidants; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Interferon-gamma; Interleukin-4; Melatonin; Mice; Mice, Inbred BALB C; Mice, Nude; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2018
Thymoquinone loaded in nanostructured lipid carrier showed enhanced anticancer activity in 4T1 tumor-bearing mice. Nanomedicine (London, England), 2018, Volume: 13, Issue:13 Topics: Allografts; Animals; Apoptosis; Benzoquinones; Breast Neoplasms; Caspase 8; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Lipids; Mammary Neoplasms, Animal; Mice; Nanostructures; Proto-Oncogene Proteins c-bcl-2; Signal Transduction	2018
Cabazitaxel and thymoquinone co-loaded lipospheres as a synergistic combination for breast cancer. Chemistry and physics of lipids, 2019, Volume: 224 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Drug Compounding; Drug Liberation; Female; Humans; Lipids; Liposomes; Optical Imaging; Solubility; Taxoids	2019
Synthesis and Characterization of PLGA-PEG Thymoquinone Nanoparticles and Its Cytotoxicity Effects in Tamoxifen-Resistant Breast Cancer Cells. Advances in experimental medicine and biology, 2020, Volume: 1292 Topics: Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Resistance, Neoplasm; Humans; Nanoparticles; Particle Size; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Tamoxifen	2020
Reverse Screening Bioinformatics Approach to Identify Potential Anti Breast Cancer Targets Using Thymoquinone from Neutraceuticals Black Cumin Oil. Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:5 Topics: Apoptosis; Benzoquinones; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Comet Assay; Computational Biology; Computer Simulation; Dietary Supplements; DNA Damage; Female; Flow Cytometry; Humans; Molecular Docking Simulation; Neoplasm Metastasis; Plant Oils	2019
Thymoquinone Augments Cyclophosphamide-Mediated\ Inhibition of Cell Proliferation in Breast Cancer Cells Asian Pacific journal of cancer prevention : APJCP, 2019, Apr-29, Volume: 20, Issue:4 Topics: Antineoplastic Agents, Alkylating; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclophosphamide; Drug Synergism; Female; Humans; Signal Transduction; Tumor Cells, Cultured	2019
Evaluation of Carum-loaded Niosomes on Breast Cancer Cells:Physicochemical Properties, In Vitro Cytotoxicity, Flow Cytometric, DNA Fragmentation and Cell Migration Assay. Scientific reports, 2019, 05-09, Volume: 9, Issue:1 Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Carum; Cell Movement; Cell Proliferation; Cell Survival; Delayed-Action Preparations; DNA Fragmentation; Female; Humans; Liposomes; MCF-7 Cells; Plant Extracts	2019
Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer. PloS one, 2013, Volume: 8, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; Benzoquinones; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Neoplasm Invasiveness; Neovascularization, Pathologic; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tamoxifen; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays	2013
Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells. Life sciences, 2013, Nov-13, Volume: 93, Issue:21 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Dose-Response Relationship, Drug; Female; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Molecular Targeted Therapy; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Signal Transduction	2013
Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS. PloS one, 2013, Volume: 8, Issue:10 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Silencing; Humans; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species; Xenograft Model Antitumor Assays	2013
Thymoquinone restores radiation-induced TGF-β expression and abrogates EMT in chemoradiotherapy of breast cancer cells. Journal of cellular physiology, 2015, Volume: 230, Issue:3 Topics: Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Transdifferentiation; Epithelial-Mesenchymal Transition; Female; Humans; Paclitaxel; Radiation; Radiotherapy; Transforming Growth Factor beta	2015
PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a. Biomaterials, 2015, Volume: 51 Topics: Actin Cytoskeleton; Animals; Benzoquinones; Breast Neoplasms; Cell Death; Cell Movement; Down-Regulation; Drug Liberation; Endocytosis; Female; Humans; MCF-7 Cells; Mice; MicroRNAs; Nanoparticles; Particle Size; Polyethylene Glycols; Polymerization; Pseudopodia; rac1 GTP-Binding Protein; RNA, Messenger; Spectroscopy, Fourier Transform Infrared; Tumor Suppressor Protein p53	2015
Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. Oncotarget, 2015, Aug-14, Volume: 6, Issue:23 Topics: Animals; Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Cell Movement; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Humans; Lung Neoplasms; Mice, Inbred BALB C; Neoplasm Invasiveness; Nuclear Proteins; Promoter Regions, Genetic; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Twist-Related Protein 1	2015
Overcoming Akt Induced Therapeutic Resistance in Breast Cancer through siRNA and Thymoquinone Encapsulated Multilamellar Gold Niosomes. Molecular pharmaceutics, 2015, Dec-07, Volume: 12, Issue:12 Topics: Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gold; Humans; MCF-7 Cells; Nanoparticles; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Tamoxifen	2015
Insights into the molecular interactions of thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer. Molecular bioSystems, 2016, Volume: 12, Issue:1 Topics: Amino Acid Sequence; Apoptosis; Apoptosis Regulatory Proteins; Benzoquinones; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Damage; Enzyme Activation; Female; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Binding; Sequence Alignment; Structure-Activity Relationship	2016
Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells. Mutation research, 2011, Jan-10, Volume: 706, Issue:1-2 Topics: Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Blotting, Western; Breast Neoplasms; Caspases; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; G2 Phase; Humans; Molecular Structure; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Suppressor Protein p53; Up-Regulation	2011
Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis. Cell biology international, 2011, Volume: 35, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Humans; Nigella sativa; Radiation, Ionizing	2011
Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway. Biochemical pharmacology, 2011, Sep-01, Volume: 82, Issue:5 Topics: Anilides; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Benzoquinones; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Movement; Female; Humans; Neoplasm Invasiveness; PPAR gamma; Proto-Oncogene Proteins c-bcl-2; Signal Transduction	2011
NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis. Biochemical and biophysical research communications, 2012, Sep-28, Volume: 426, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Dicumarol; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; NAD(P)H Dehydrogenase (Quinone)	2012
Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer. Drug delivery, 2012, Volume: 19, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Benzoquinones; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Compounding; Drug Stability; Female; Fibroblasts; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Molecular Structure; Octoxynol; Particle Size; Solubility; Surface Properties	2012