Compounds > thymoquinone
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thymoquinone and Acute Lymphoid Leukemia

thymoquinone has been researched along with Acute Lymphoid Leukemia in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdelwahab, SI; Ibrahim, MY; Kamalidehghan, B; Mohan, S; Othman, R; Salim, LZ; Sheikh, BY1
Abusnina, A; Achour, M; Alhosin, M; Bronner, C; Chataigneau, T; Fuhrmann, G; Lugnier, C; Muller, C; Peluso, J; Schini-Kerth, VB; Sharif, T1
Abusnina, A; Alhosin, M; Bronner, C; Fuhrmann, G; Keravis, T; Lugnier, C; Muller, CD1
Alhosin, M; Auger, C; Boukhari, A; Gies, JP; Ibrahim, A; Schini-Kerth, VB; Sharif, T1

Other Studies

4 other study(ies) available for thymoquinone and Acute Lymphoid Leukemia

ArticleYear
Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro.
    Molecules (Basel, Switzerland), 2013, Sep-12, Volume: 18, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Benzoquinones; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Screening Assays, Antitumor; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species

2013
Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1.
    Biochemical pharmacology, 2010, May-01, Volume: 79, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; CCAAT-Enhancer-Binding Proteins; Cell Cycle; DNA-Binding Proteins; Gene Expression Regulation; Humans; Jurkat Cells; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Protein p73; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2010
Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis.
    Cellular signalling, 2011, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 1; DNA-Binding Proteins; Down-Regulation; Humans; Isoenzymes; Jurkat Cells; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA Interference; Tumor Protein p73; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2011
Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts.
    Investigational new drugs, 2012, Volume: 30, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Astrocytoma; Benzoquinones; Cell Line, Tumor; DNA-Binding Proteins; Fibroblasts; Humans; Jurkat Cells; Nuclear Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteolysis; Tubulin; Tumor Protein p73; Tumor Suppressor Proteins; Up-Regulation

2012