Page last updated: 2024-08-21

thymoquinone and Acute Liver Injury, Drug-Induced

thymoquinone has been researched along with Acute Liver Injury, Drug-Induced in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's15 (68.18)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Akin, AT; Karabulut, D; Kaymak, E; Öztürk, E; Yakan, B1
Amali, A; Danaei, GH; Karami, M; Khorrami, MB; Riahi-Zanjani, B; Sadeghi, M1
Abdel Moneim, AE; Al Aboud, D; Alsharif, KF; Amin, HK; Baty, RS; Elmahallawy, EK; Habotta, OA; Hassan, KE; Kassab, RB; Zhery, AS1
Abidi, S; Alam, T; Farooqui, Z; Khan, F; Parwez, I; Shahid, F1
El-Magd, MA; El-Said, KS; El-Sharnouby, M; Mohamed, AE; Salama, AF; Tousson, EM1
Mabrouk, A1
Azirak, S; Bilgic, S; Guvenc, AN; Kocaman, N; Ozer, MK; Tastemir Korkmaz, D1
Aksungur, Z; Bag, HG; Erdemli, ME; Gul, M; Gul, S; Yigitcan, B1
Balak, F; Hasanzadeh, G; Nili-Ahmadabadi, A; Sabzevari, O; Zeinvand-Lorestani, H1
Akbas Tosunoglu, E; Bayındır, N; Bulut, H; Esrefoglu, M; Kurbetli, N; Meral, I; Meydan, S; Ozturk, O; Selek, S1
Bhadauria, M; Jaswal, A; Shrivastava, S; Shukla, S; Sinha, N1
Fan, J; Gao, X; Ghazwani, M; Li, J; Li, S; Zhang, Y1
Aycan, IÖ; Evliyaoğlu, O; Fırat, U; Kavak, GÖ; Tokgöz, O; Tüfek, A; Turgut, H; Yüksel, MU1
Suddek, GM1
Al-Malki, AL; Sayed, AA1
Ahmed, OM; Galaly, SR; Mahmoud, AM1
Abdel-Wahab, WM1
Bel Hadj Salah, I; Ben Cheikh, H; Chaieb, W; Mabrouk, A1
Bai, T; Lian, LH; Nan, JX; Wu, YL; Yang, Y; Yao, YL; Zhang, DQ1
Helal, GK1
Al-Sawaf, HA; Al-Shabanah, OA; El-Hadiyah, T; El-Khatib, AS; Ginawi, OT; Mansour, MA1
Mansour, MA1

Other Studies

22 other study(ies) available for thymoquinone and Acute Liver Injury, Drug-Induced

ArticleYear
Therapeutic effects of thymoquinone in doxorubicin-induced hepatotoxicity via oxidative stress, inflammation and apoptosis.
    Anatomia, histologia, embryologia, 2021, Volume: 50, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Chemical and Drug Induced Liver Injury; Doxorubicin; Inflammation; Oxidative Stress; Rats; Rodent Diseases

2021
The significance of thymoquinone administration on liver toxicity of diazinon and cholinesterase activity; a recommendation for prophylaxis among individuals at risk.
    BMC complementary medicine and therapies, 2022, Dec-05, Volume: 22, Issue:1

    Topics: Acetylcholinesterase; Alkaline Phosphatase; Animals; Antioxidants; Butyrylcholinesterase; Chemical and Drug Induced Liver Injury; Diazinon; Glutathione; Hepatitis; Organophosphorus Compounds; Pesticides; Rats; Superoxide Dismutase

2022
Protective efficacy of thymoquinone or ebselen separately against arsenic-induced hepatotoxicity in rat.
    Environmental science and pollution research international, 2021, Volume: 28, Issue:5

    Topics: Animals; Antioxidants; Arsenic; Azoles; Benzoquinones; Chemical and Drug Induced Liver Injury; Female; Isoindoles; Liver; Organoselenium Compounds; Oxidative Stress; Rats

2021
Thymoquinone supplementation ameliorates cisplatin-induced hepatic pathophysiology.
    Human & experimental toxicology, 2021, Volume: 40, Issue:10

    Topics: Animals; Antineoplastic Agents; Benzoquinones; Chemical and Drug Induced Liver Injury; Cisplatin; Dietary Supplements; Humans; Male; Random Allocation; Rats; Rats, Wistar

2021
Potential therapeutic effect of thymoquinone and/or bee pollen on fluvastatin-induced hepatitis in rats.
    Scientific reports, 2021, 08-03, Volume: 11, Issue:1

    Topics: Animals; Antioxidants; Bees; Benzoquinones; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Management; Disease Susceptibility; Fluvastatin; Gene Expression; Hepatitis, Animal; Immunohistochemistry; Liver Function Tests; Oxidative Stress; Pollen; Rats; Treatment Outcome

2021
Protective effect of thymoquinone against lead-induced antioxidant defense system alteration in rat liver.
    Acta biologica Hungarica, 2017, Volume: 68, Issue:3

    Topics: Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Lead Poisoning; Liver; Male; Organometallic Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Treatment Outcome

2017
The protective effect of thymoquinone over olanzapine-induced side effects in liver, and metabolic side effects.
    Bratislavske lekarske listy, 2017, Volume: 118, Issue:10

    Topics: Alanine Transaminase; Animals; Antipsychotic Agents; Aspartate Aminotransferases; Benzodiazepines; Benzoquinones; Blood Glucose; Chemical and Drug Induced Liver Injury; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; gamma-Glutamyltransferase; Liver; Olanzapine; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Triglycerides

2017
Thymoquinone is protective against 2,3,7,8-tetrachlorodibenzo-p-dioxin induced hepatotoxicity.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2018, Volume: 93, Issue:6

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Benzoquinones; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Oxidation-Reduction; Oxidative Stress; Polychlorinated Dibenzodioxins; Rats, Wistar; Superoxide Dismutase

2018
Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice.
    Pesticide biochemistry and physiology, 2018, Volume: 148

    Topics: Animals; Antioxidants; Benzoquinones; Biomarkers; Catalase; Chemical and Drug Induced Liver Injury; GTP-Binding Proteins; Herbicides; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Liver Function Tests; Male; Mice; Oxidative Stress; Paraquat; Protein Glutamine gamma Glutamyltransferase 2; Sulfhydryl Compounds; Superoxide Dismutase; Transglutaminases; Vitamin E

2018
Protective effects of caffeic acid phenethyl ester and thymoquinone on toluene induced liver toxicity.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2019, Volume: 94, Issue:4

    Topics: Animals; Benzoquinones; Caffeic Acids; Chemical and Drug Induced Liver Injury; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Toluene

2019
Therapeutic potential of thymoquinone against anti-tuberculosis drugs induced liver damage.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:3

    Topics: Analysis of Variance; Animals; Antitubercular Agents; Benzoquinones; Blood Chemical Analysis; Chemical and Drug Induced Liver Injury; Ethambutol; Female; Isoniazid; Kidney; Lipid Peroxidation; Lipids; Liver; Liver Function Tests; Pyrazinamide; Rats; Rats, Sprague-Dawley; Rifampin; Superoxide Dismutase

2013
Anti-fibrotic effect of thymoquinone on hepatic stellate cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Feb-15, Volume: 21, Issue:3

    Topics: Actins; Animals; Anti-Inflammatory Agents; Benzoquinones; Cell Transdifferentiation; Chemical and Drug Induced Liver Injury; Chemokine CCL2; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Fibrosis; Hepatic Stellate Cells; Humans; Interleukin-6; Lipopolysaccharides; Liver; Liver Cirrhosis; Male; NF-kappa B; Nigella sativa; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger

2014
Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats.
    International journal of surgery (London, England), 2014, Volume: 12, Issue:3

    Topics: Acetaminophen; Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Glutathione Disulfide; Oxidoreductases; Rats; Rats, Wistar

2014
Protective role of thymoquinone against liver damage induced by tamoxifen in female rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:8

    Topics: Animals; Antineoplastic Agents, Hormonal; Benzoquinones; Chemical and Drug Induced Liver Injury; Estrogen Antagonists; Female; Liver; Nigella sativa; Protective Agents; Rats, Sprague-Dawley; Tamoxifen

2014
Thymoquinone attenuates cisplatin-induced hepatotoxicity via nuclear factor kappa-β.
    BMC complementary and alternative medicine, 2014, Aug-03, Volume: 14

    Topics: Animals; Anti-Inflammatory Agents; Benzoquinones; Chemical and Drug Induced Liver Injury; Cisplatin; Cytokines; Drug Interactions; Liver; Male; NF-kappa B; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Signal Transduction

2014
Thymoquinone and curcumin prevent gentamicin-induced liver injury by attenuating oxidative stress, inflammation and apoptosis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:6

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Benzoquinones; Caspase 3; Chemical and Drug Induced Liver Injury; Curcumin; Gentamicins; Glutathione; Glutathione Peroxidase; L-Lactate Dehydrogenase; Liver; Male; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2014
Thymoquinone attenuates toxicity and oxidative stress induced by bisphenol A in liver of male rats.
    Pakistan journal of biological sciences : PJBS, 2014, Volume: 17, Issue:11

    Topics: Animals; Antioxidants; Benzhydryl Compounds; Benzoquinones; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Lipid Peroxidation; Liver; Male; Organ Size; Oxidative Stress; Phenols; Rats, Sprague-Dawley; Time Factors

2014
Protective effect of thymoquinone against lead-induced hepatic toxicity in rats.
    Environmental science and pollution research international, 2016, Volume: 23, Issue:12

    Topics: Animals; Antioxidants; Benzoquinones; Chemical and Drug Induced Liver Injury; Dietary Supplements; Disease Models, Animal; Environmental Pollutants; Lead; Lipid Peroxidation; Liver; Liver Function Tests; Male; Nigella sativa; Oils, Volatile; Random Allocation; Rats, Wistar; Seeds

2016
Upregulation of SIRT1-AMPK by thymoquinone in hepatic stellate cells ameliorates liver injury.
    Toxicology letters, 2016, Nov-16, Volume: 262

    Topics: Adenylate Kinase; Alcoholism; AMP-Activated Protein Kinase Kinases; Animals; Benzoquinones; Binge Drinking; Chemical and Drug Induced Liver Injury; Hepatic Stellate Cells; Humans; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Protein Serine-Threonine Kinases; Sirtuin 1; Transforming Growth Factor beta; Up-Regulation

2016
Thymoquinone supplementation ameliorates acute endotoxemia-induced liver dysfunction in rats.
    Pakistan journal of pharmaceutical sciences, 2010, Volume: 23, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Benzoquinones; Caspase 3; Chemical and Drug Induced Liver Injury; Endotoxemia; Glutathione; Lipopolysaccharides; Male; Malondialdehyde; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2010
Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone.
    Research communications in molecular pathology and pharmacology, 2001, Volume: 110, Issue:3-4

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Bicyclic Monoterpenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cymenes; Dose-Response Relationship, Drug; L-Lactate Dehydrogenase; Male; Mice; Monoterpenes; Oils, Volatile; Plant Oils; Terpenes

2001
Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice.
    Life sciences, 2000, May-19, Volume: 66, Issue:26

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoquinones; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Deferoxamine; Iron Chelating Agents; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Mice

2000