thymopoietin-iii and Lung-Abscess

Patients with acute lung abscesses and bronchiectatic diseases manifested deep changes in the immune responsiveness, which were largely of compensatory (elevation of IgA content to over 2 mg/ml), immunosuppressive (decrease of lymphocyte blast transformation with PHA down to 52.2 and 48.6%) or autoimmune (increase of spontaneous lymphocyte blast transformation up to 8%) character. In patients with acute lung abscesses, the indicators enumerated tended during treatment toward normalization which was not over in the majority of them by the discharge from hospital. In patients with bronchiectatic disease, that tendency was observable only after additional treatment with immunocorrective drugs (levamisole, splenin).

Topics: Anti-Bacterial Agents; Bronchiectasis; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunotherapy; Levamisole; Lung Abscess; Lymphocyte Activation; Rosette Formation; T-Lymphocytes; Thymopoietins; Time Factors