Page last updated: 2024-08-17

thymol and Disease Models, Animal

thymol has been researched along with Disease Models, Animal in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.86)18.7374
1990's1 (2.86)18.2507
2000's1 (2.86)29.6817
2010's28 (80.00)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Baker, MT; Mishra, RK1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Choi, HJ; Dash, R; Haque, MN; Moon, IS; Timalsina, B1
Chen, J; Li, Y; Lv, M; Tang, B; Wang, F; Xiong, Y; Zhang, H1
Büyük, B; Gulcin, İ; Kılınç, N; Ovalı, MA; Öztopuz, RÖ; Şehitoğlu, MH1
Capibaribe, VCC; Chaves, RC; da Silva, DMA; de Araujo, MA; de Carvalho, AMR; de Oliveira, NF; de Sousa, FCF; de Vasconcelos, SMM; Fernandes, ML; Lopes, IS; Macêdo, DS; Maia Chaves Filho, AJ; Oliveira, ICM; Valentim, JT; Vasconcelos Mallmann, AS1
Abtahi Froushani, SM; Golbahari, S1
Chen, S; Hang, B; Hu, J; Jiang, J; Lei, L; Li, M; Qin, W; Richard, LP; Sun, Y; Wang, L; Wang, T; Xia, X; Xu, Y; Zhang, G; Zhao, X; Zhu, C1
Huang, S; Jiang, S; Meng, D; Wan, L; Wan, S; Wang, H; Wei, L; Yu, P1
Hou, G; Liu, Z; Wang, L; Yao, L; Zuo, XS1
Asadbegi, M; Ebrahim-Habibi, A; Golipoor, Z; Komaki, A; Salehi, I; Sarihi, A; Shahidi, S; Soleimani Asl, S; Yaghmaei, P1
Araújo, MM; Arruda, C; Carvalho, T; Marcato, PD; Pivetta, TP; Simões, S1
Ansari, HS; Haque, MR1
Kryshen, K; Lehner, MD; Pongrácz, JE; Seibel, J1
Ghafarzadegan, K; Mahjoub, S; Mohammadi, A; Nouri, HR1
Aljarba, TM; Gibbons, S; Skalicka-Woźniak, K; Stapleton, P; Walasek, M; Xiao, J; Łuszczki, JJ1
Dortbudak, MB; Gozeler, MS; Kandemir, FM; Kilic, K; Kucukler, S; Sakat, MS; Yildirim, S1
Ansari, SA; Azimullah, S; Javed, H; Meeran, MFN; Ojha, S1
Chaudhari, R; Jain, P; Patil, S; Sancheti, J; Sathaye, S; Shaikh, MF; Somani, G1
Ahmad, MA; Ansari, SH; Haque, MR; Najmi, AK1
Bryce, PJ; Hsu, CL; Wechsler, JB1
Akashe, A; Bissinger, BW; Howell, SB; Kaplan, RM; Lee, MD; Mason, ME; Mitchell, SM; Pedroso, AA; Skrypec, DJ; Storey, BE; Vidyashankar, AN1
Chen, JJ; Deng, XY; Fu, Q; Li, HY; Li, RP; Ma, SP; Qu, R1
Pari, L; Saravanan, S1
Araújo-Filho, I; Bannet, M; Barros, G; Botelho, MA; Campus, G; Carvalho, CF; Gouvea, J; Patrus, D; Patrus, L; Queiroz, DB; Rego, A; Silva, I1
Haunschild, J; Kryshen, K; Lehner, MD; Pergola, C; Seibel, J; Werz, O; Wosikowski, K1
Albuquerque-Júnior, RL; Diniz, PB; Pinheiro, MS; Ribeiro, AR; Thomazzi, SM1
Beleboni, RO; Benincasa, BI; Chagas, ACS; Contini, SSHT; Fachin, AL; Ferreira, LE; França, SC1
de Oliveira, EA; Games, E; Guerreiro, M; Lago, JH; Lopes, FD; Martins, MA; Olivo, CR; Pinheiro, NM; Prado, CM; Santana, FR; Tibério, IF1
Borlina, SC; de Souza, V; Dezan Junior, E; Gomes-Filho, JE; Holland, R; Marion, JJ; Murata, SS; Neto, Ddos A1
Azizi, Z; Ebrahimi, S; Kamalinejad, M; Majlessi, N; Saadatfar, E1
Denegri, GM; Elissondo, MC; Pensel, PE1
Anderson, HR; Archer, DB; Gardiner, TA; Lloyd, SJ; Stitt, AW1
Bowen, WH; Harper, DS; Kohut, BE; Luo, D; Pearson, SK; Yu, D1
Crocker, BD; Denborough, MA; Okumura, F1

Other Studies

35 other study(ies) available for thymol and Disease Models, Animal

ArticleYear
Seizure prevention by the naturally occurring phenols, carvacrol and thymol in a partial seizure-psychomotor model.
    Bioorganic & medicinal chemistry letters, 2014, Dec-01, Volume: 24, Issue:23

    Topics: Animals; Anticonvulsants; Cymenes; Disease Models, Animal; Monoterpenes; Phenols; Psychomotor Performance; Seizures; Thymol

2014
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Thymol in Trachyspermum ammi seed extract exhibits neuroprotection, learning, and memory enhancement in scopolamine-induced Alzheimer's disease mouse model.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:7

    Topics: Alzheimer Disease; Ammi; Animals; Apiaceae; Disease Models, Animal; Mice; Neuroprotection; Neuroprotective Agents; Plant Extracts; Scopolamine; Thymol

2023
Thymol improves autism-like behaviour in VPA-induced ASD rats through the Pin1/p38 MAPK pathway.
    International immunopharmacology, 2023, Volume: 117

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Female; Humans; Inflammation; NIMA-Interacting Peptidylprolyl Isomerase; p38 Mitogen-Activated Protein Kinases; Prenatal Exposure Delayed Effects; Rats; Thymol; Valproic Acid

2023
Thymol regulates the Endothelin-1 at gene expression and protein synthesis levels in septic rats.
    Chemico-biological interactions, 2023, Apr-25, Volume: 375

    Topics: Animals; Disease Models, Animal; Endothelin-1; Gene Expression; Molecular Docking Simulation; Rats; Sepsis; Superoxide Dismutase; Thymol; Tumor Necrosis Factor-alpha

2023
Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:12

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Disease Models, Animal; Female; Fluvoxamine; Hippocampus; Maze Learning; Mice; Thymol; Up-Regulation

2019
Synergistic benefits of Nicotine and Thymol in alleviating experimental rheumatoid arthritis.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Drug Synergism; Freund's Adjuvant; Male; Nicotine; Rats; Rats, Wistar; Thymol

2019
Thymol kills bacteria, reduces biofilm formation, and protects mice against a fatal infection of Actinobacillus pleuropneumoniae strain L20.
    Veterinary microbiology, 2017, Volume: 203

    Topics: Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Anti-Infective Agents; Biofilms; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Thymol; Virulence

2017
Preventive and Therapeutic Effects of Thymol in a Lipopolysaccharide-Induced Acute Lung Injury Mice Model.
    Inflammation, 2018, Volume: 41, Issue:1

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Lung; Male; Malondialdehyde; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Peroxidase; Superoxide Dismutase; Thymol; Tumor Necrosis Factor-alpha

2018
Protective effects of thymol on LPS-induced acute lung injury in mice.
    Microbial pathogenesis, 2018, Volume: 116

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Histocytochemistry; Lipopolysaccharides; Lung; Male; Mice, Inbred BALB C; Thymol

2018
Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet.
    Brain research bulletin, 2018, Volume: 137

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Diet, High-Fat; Disease Models, Animal; Electrodes, Implanted; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Malondialdehyde; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Plaque, Amyloid; Random Allocation; Rats, Wistar; Thymol

2018
Development of nanoparticles from natural lipids for topical delivery of thymol: Investigation of its anti-inflammatory properties.
    Colloids and surfaces. B, Biointerfaces, 2018, Apr-01, Volume: 164

    Topics: Administration, Topical; Aminoquinolines; Animals; Anti-Inflammatory Agents; Antioxidants; Betamethasone; Cell Death; Cell Line; Cell Survival; Disease Models, Animal; Drug Compounding; Drug Liberation; Ear; Edema; Humans; Imiquimod; Inflammation; Keratinocytes; Lipids; Mice, Inbred BALB C; Nanoparticles; Particle Size; Permeability; Psoriasis; Rheology; Skin; Sus scrofa; Thymol

2018
Anti-Obesity Effect of Arq Zeera and Its Main Components Thymol and Cuminaldehyde in High Fat Diet Induced Obese Rats.
    Drug research, 2018, Volume: 68, Issue:11

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Benzaldehydes; Blood Glucose; Cymenes; Diet, High-Fat; Disease Models, Animal; Humans; India; Leptin; Lipase; Lipid Metabolism; Lipids; Liver; Male; Medicine, Unani; Obesity; Orlistat; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Thymol; Treatment Outcome

2018
In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts.
    Pulmonary pharmacology & therapeutics, 2018, Volume: 51

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Lipopolysaccharides; Male; Mucin 5AC; Mucus; Pneumonia; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Respiratory Mucosa; RNA, Messenger; Thymol

2018
Immunomodulatory effects of Thymol through modulation of redox status and trace element content in experimental model of asthma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Animals; Asthma; Disease Models, Animal; Female; Immunologic Factors; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidation-Reduction; Oxidative Stress; Thymol; Trace Elements; Treatment Outcome

2018
The anticonvulsant and anti-plasmid conjugation potential of Thymus vulgaris chemistry: An in vivo murine and in vitro study.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 120

    Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Camphanes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Disease Models, Animal; Escherichia coli; Eugenol; Gas Chromatography-Mass Spectrometry; Male; Mice; Monoterpenes; Plant Extracts; Plant Oils; Plasmids; Seizures; Thymol; Thymus Plant

2018
The amendatory effect of hesperidin and thymol in allergic rhinitis: an ovalbumin-induced rat model.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019, Volume: 276, Issue:2

    Topics: Animals; Anti-Infective Agents; Antioxidants; Disease Models, Animal; Hesperidin; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-5; Nasal Cavity; Ovalbumin; Oxidants; Rats, Sprague-Dawley; Rhinitis, Allergic; Thymol; Tumor Necrosis Factor-alpha

2019
Neuroprotective Effects of Thymol, a Dietary Monoterpene Against Dopaminergic Neurodegeneration in Rotenone-Induced Rat Model of Parkinson's Disease.
    International journal of molecular sciences, 2019, Mar-27, Volume: 20, Issue:7

    Topics: Animals; Catalase; Cyclooxygenase 2; Cytokines; Diet; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Neostriatum; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Wistar; Rotenone; Substantia Nigra; Superoxide Dismutase; Thymol; Tyrosine 3-Monooxygenase

2019
Characterization of anticonvulsant and antiepileptogenic potential of thymol in various experimental models.
    Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:1

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Thymol

2014
Monoterpene phenolic compound thymol prevents high fat diet induced obesity in murine model.
    Toxicology mechanisms and methods, 2014, Volume: 24, Issue:2

    Topics: Animals; Antioxidants; Biomarkers; Body Weight; Diet, High-Fat; Disease Models, Animal; Feeding Behavior; Kidney Function Tests; Liver Function Tests; Male; Mice; Obesity; Organ Size; Rats, Wistar; Thymol

2014
IgE-mediated mast cell responses are inhibited by thymol-mediated, activation-induced cell death in skin inflammation.
    The Journal of allergy and clinical immunology, 2014, Volume: 133, Issue:6

    Topics: Anaphylaxis; Animals; Apoptosis; Calcium; Cell Death; Cell Degranulation; Cell Survival; Dermatitis; Disease Models, Animal; Histamine; Immunoglobulin E; Mast Cells; Mice; Peritoneal Cavity; Thymol; Transcription, Genetic; Transient Receptor Potential Channels; TRPA1 Cation Channel

2014
Antiparasitic efficacy of a novel plant-based functional food using an Ascaris suum model in pigs.
    Acta tropica, 2014, Volume: 139

    Topics: Animals; Antinematodal Agents; Ascariasis; Ascaris suum; Bicyclic Monoterpenes; Cymenes; Disease Models, Animal; Female; Food Additives; Monoterpenes; Oils, Volatile; Parasite Egg Count; Plant Oils; Random Allocation; Sus scrofa; Thymol

2014
Thymol produces an antidepressant-like effect in a chronic unpredictable mild stress model of depression in mice.
    Behavioural brain research, 2015, Sep-15, Volume: 291

    Topics: Animals; Antidepressive Agents; Carrier Proteins; Caspase 1; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Mice, Inbred ICR; NLR Family, Pyrin Domain-Containing 3 Protein; Norepinephrine; Random Allocation; Serotonin; Stress, Psychological; Thymol; Tumor Necrosis Factor-alpha

2015
Role of thymol on hyperglycemia and hyperlipidemia in high fat diet-induced type 2 diabetic C57BL/6J mice.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Glycated Hemoglobin; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Liver; Male; Mice, Inbred C57BL; Thymol; Time Factors

2015
Nanotechnology in Phytotherapy: Antiinflammatory Effect of a Nanostructured Thymol Gel from Lippia sidoides in Acute Periodontitis in Rats.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:1

    Topics: Animals; Brazil; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Gels; Gingiva; Lippia; Male; Nanotechnology; Neutrophils; Oils, Volatile; Periodontitis; Peroxidase; Phytotherapy; Plant Leaves; Plant Oils; Rats; Rats, Wistar; Thymol

2016
Bronchipret® syrup containing thyme and ivy extracts suppresses bronchoalveolar inflammation and goblet cell hyperplasia in experimental bronchoalveolitis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Dec-01, Volume: 22, Issue:13

    Topics: Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Goblet Cells; Humans; Hyperplasia; Inflammation; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Monocytes; Neutrophils; Plant Extracts; Rats; Rats, Wistar; Thymol; Thymus Plant

2015
Gastroprotective effects of thymol on acute and chronic ulcers in rats: The role of prostaglandins, ATP-sensitive K(+) channels, and gastric mucus secretion.
    Chemico-biological interactions, 2016, Jan-25, Volume: 244

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Mucins; Helicobacter pylori; KATP Channels; Male; Microbial Sensitivity Tests; Mucus; Prostaglandins; Protective Agents; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Thymol

2016
Thymus vulgaris L. essential oil and its main component thymol: Anthelmintic effects against Haemonchus contortus from sheep.
    Veterinary parasitology, 2016, Sep-15, Volume: 228

    Topics: Animals; Anthelmintics; Disease Models, Animal; Ethnopharmacology; Haemonchiasis; Haemonchus; Larva; Levamisole; Male; Oils, Volatile; Phytochemicals; Plant Extracts; Plant Oils; Sheep; Sheep Diseases; Thymol; Thymus Plant

2016
Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema.
    Molecules (Basel, Switzerland), 2016, Oct-20, Volume: 21, Issue:10

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cymenes; Disease Models, Animal; Emphysema; Gene Expression Regulation; Interleukins; Lippia; Macrophages, Alveolar; Mice; Monoterpenes; Oils, Volatile; Pancreatic Elastase; Plant Leaves; Thymol

2016
Influence of apical foramen widening and sealer on the healing of chronic periapical lesions induced in dogs' teeth.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:6

    Topics: Animals; Bismuth; Bone Resorption; Calcium Hydroxide; Dental Cementum; Dexamethasone; Disease Models, Animal; Dogs; Drug Combinations; Formaldehyde; Hydrocortisone; Periapical Diseases; Periodontal Ligament; Root Canal Filling Materials; Root Canal Irrigants; Root Canal Preparation; Statistics, Nonparametric; Thymol; Tooth Apex

2010
Cognitive-enhancing activity of thymol and carvacrol in two rat models of dementia.
    Behavioural pharmacology, 2012, Volume: 23, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cholinesterase Inhibitors; Cognition; Cymenes; Dementia; Disease Models, Animal; Male; Mice; Monoterpenes; Rats; Rats, Wistar; Scopolamine; Thymol

2012
Could thymol have effectiveness on scolices and germinal layer of hydatid cysts?
    Acta tropica, 2013, Volume: 125, Issue:3

    Topics: Animals; Anthelmintics; Disease Models, Animal; Echinococcosis; Echinococcus granulosus; Female; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Survival Analysis; Thymol

2013
Induction of alloxan/streptozotocin diabetes in dogs: a revised experimental technique.
    Laboratory animals, 1993, Volume: 27, Issue:3

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Glucose; Reproducibility of Results; Streptozocin; Thymol

1993
Caries inhibition efficacy of an antiplaque/antigingivitis dentifrice.
    American journal of dentistry, 2000, Volume: 13, Issue:Spec No

    Topics: Analysis of Variance; Animals; Anti-Infective Agents, Local; Cariostatic Agents; Cyclohexanols; Dental Caries; Dental Plaque; Dentifrices; Diet, Cariogenic; Disease Models, Animal; Eucalyptol; Eucalyptus; Fluorides; Gingivitis; Menthol; Monoterpenes; Oils, Volatile; Pharmaceutical Vehicles; Phosphates; Placebos; Random Allocation; Rats; Rats, Sprague-Dawley; Salicylates; Silicon Dioxide; Single-Blind Method; Streptococcus sobrinus; Terpenes; Thymol

2000
Identification of susceptibility to malignant hyperpyrexia in swine.
    British journal of anaesthesia, 1979, Volume: 51, Issue:3

    Topics: Animals; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Succinylcholine; Swine; Thymol

1979