thymine has been researched along with Malignant Melanoma in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine." | 3.81 | Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. ( Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB, 2015) |
| "We tested 17 malignant mucosal melanomas of the head and neck for the thymine (T)-->adenine (A) missense mutation at nucleotide 1796 in the BRAF gene using direct sequencing and a newly developed assay that uses a novel primer extension method (Mutector assay)." | 3.72 | Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites. ( Begum, S; Cohen, Y; Esche, C; Goldenberg, D; Lavie, O; Rosenbaum, E; Sidransky, D; Westra, WH, 2004) |
| "Following exposure to ultraviolet irradiation (UV), two of three human fibroblast strains and one of three melanoma cell lines showed lower rates of thymine dimer excision during 24 h at 40 degrees C than at 36 degrees C." | 3.65 | Temperature-sensitive DNA repair of ultraviolet damage in human cell lines. ( Goss, P; Parsons, PG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, KH | 1 |
| Wu, YS | 1 |
| Hall, IH | 1 |
| Premi, S | 1 |
| Wallisch, S | 1 |
| Mano, CM | 1 |
| Weiner, AB | 1 |
| Bacchiocchi, A | 1 |
| Wakamatsu, K | 1 |
| Bechara, EJ | 1 |
| Halaban, R | 1 |
| Douki, T | 1 |
| Brash, DE | 1 |
| Cohen, Y | 1 |
| Rosenbaum, E | 1 |
| Begum, S | 1 |
| Goldenberg, D | 1 |
| Esche, C | 1 |
| Lavie, O | 1 |
| Sidransky, D | 1 |
| Westra, WH | 1 |
| Liu, L | 1 |
| Dilworth, D | 1 |
| Gao, L | 1 |
| Monzon, J | 1 |
| Summers, A | 1 |
| Lassam, N | 1 |
| Hogg, D | 1 |
| Harland, M | 1 |
| Holland, EA | 1 |
| Ghiorzo, P | 1 |
| Mantelli, M | 1 |
| Bianchi-Scarrà, G | 1 |
| Goldstein, AM | 1 |
| Tucker, MA | 1 |
| Ponder, BA | 1 |
| Mann, GJ | 1 |
| Bishop, DT | 1 |
| Newton Bishop, J | 1 |
| Goss, P | 1 |
| Parsons, PG | 1 |
| Chalmers, AH | 1 |
| Lavin, M | 1 |
| Atisoontornkul, S | 1 |
| Mansbridge, J | 1 |
| Kidson, C | 1 |
| Lockshin, A | 1 |
| Giovanella, BC | 1 |
| Stehlin, JS | 1 |
| Kozielski, T | 1 |
| Quian, C | 1 |
| Apperson, RW | 1 |
| Fedorov, NA | 1 |
| Matveenko, VN | 1 |
| Tikhonova, EF | 1 |
9 other studies available for thymine and Malignant Melanoma
| Article | Year |
|---|---|
Antitumor agents. 25. Synthesis and antitumor activity of uracil and thymine alpha-methylene-gamma-lactones and related derivatives.
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Lactones; Leukemia, Experimental; Male; Melan | 1977 |
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes; | 2015 |
Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites.
Topics: Adenine; DNA; Exons; Head and Neck Neoplasms; Humans; Melanocytes; Melanoma; Models, Genetic; Mutage | 2004 |
Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma.
Topics: 5' Untranslated Regions; Alleles; Cell Line, Transformed; Codon, Initiator; Cyclin-Dependent Kinase | 1999 |
Mutation screening of the CDKN2A promoter in melanoma families.
Topics: Adolescent; Adult; Aged; Cyclin-Dependent Kinase Inhibitor p16; DNA, Neoplasm; Genetic Predispositio | 2000 |
Temperature-sensitive DNA repair of ultraviolet damage in human cell lines.
Topics: Autoradiography; Cell Line; DNA; DNA Repair; Fibroblasts; Humans; Melanoma; Radiation Effects; Tempe | 1976 |
Resistance of human melanoma cells to ultraviolet radiation.
Topics: Cell Line; Cell Survival; Cells, Cultured; Clone Cells; DNA; DNA Repair; Melanins; Melanoma; Radiati | 1976 |
Antitumor activity and minimal toxicity of concentrated thymidine infused in nude mice.
Topics: Animals; Antineoplastic Agents; Male; Melanoma; Mice; Mice, Nude; Solubility; Thymidine; Thymine | 1985 |
[Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma].
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Melan | 1970 |