thymine has been researched along with HIV in 11 studies
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Substructural Molecular Fragments (SMF) method was applied for computer-aided design of new compounds potentially possessing high anti-HIV activities: tetrahydroimidazobenzodiazepinone (TIBO) derivatives and 1-[2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) derivatives." | 3.73 | "In silico" design of potential anti-HIV actives using fragment descriptors. ( Solov'ev, VP; Varnek, A, 2005) |
| " Mean oral bioavailability of D4T was high at approximately 70%." | 1.29 | In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine. ( Cretton, EM; Hitchcock, MJ; Kaul, S; Kidd, LB; McClure, HM; Sommadossi, JP; Zhou, Z, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, Q | 1 |
| Herdewijn, P | 1 |
| Varnek, A | 1 |
| Solov'ev, VP | 1 |
| Liang, Y | 1 |
| Narayanasamy, J | 1 |
| Schinazi, RF | 1 |
| Chu, CK | 1 |
| D'Cruz, OJ | 1 |
| Uckun, FM | 1 |
| Boyer, PL | 1 |
| Currens, MJ | 1 |
| McMahon, JB | 1 |
| Boyd, MR | 1 |
| Hughes, SH | 1 |
| Cretton, EM | 1 |
| Zhou, Z | 1 |
| Kidd, LB | 1 |
| McClure, HM | 1 |
| Kaul, S | 1 |
| Hitchcock, MJ | 1 |
| Sommadossi, JP | 1 |
| Racha, S | 1 |
| Vargeese, C | 1 |
| Vemishetti, P | 1 |
| El-Subbagh, HI | 1 |
| Abushanab, E | 1 |
| Panzica, RP | 1 |
| Giovannangéli, C | 1 |
| Rougée, M | 1 |
| Garestier, T | 1 |
| Thuong, NT | 1 |
| Hélène, C | 1 |
| Idegami, K | 1 |
| Ikeda, K | 1 |
| Achiwa, K | 1 |
| Griffin, LC | 1 |
| Dervan, PB | 1 |
| Agyei-Aye, K | 1 |
| Baker, DC | 1 |
1 review available for thymine and HIV
| Article | Year |
|---|---|
Novel tight binding PETT, HEPT and DABO-based non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Acquired Immunodeficiency Syndrome; Anti-Retroviral Agents; Chemistry, Pharmaceutical; Drug Design; | 2006 |
10 other studies available for thymine and HIV
| Article | Year |
|---|---|
Synthesis of 3'-o-phosphonoethyl nucleosides with an adenine and a thymine base moiety.
Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Hepacivirus; HIV; Humans; Microbial Sensitivity | 2009 |
"In silico" design of potential anti-HIV actives using fragment descriptors.
Topics: Anti-HIV Agents; Benzodiazepines; Combinatorial Chemistry Techniques; Drug Design; HIV; Imidazoles; | 2005 |
Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
Topics: Amides; Animals; Anti-HIV Agents; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Dioxol | 2006 |
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase.
Topics: Amino Acid Sequence; Antiviral Agents; Benzimidazoles; Coumarins; Drug Resistance, Microbial; HIV; H | 1993 |
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine.
Topics: Aminoisobutyric Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Chroma | 1993 |
Synthesis and biological evaluation of1',2'-seconucleo-5'- phosphonates.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cystine; HIV; Molecular Structure; Nucleotides; Orga | 1996 |
Triple-helix formation by oligonucleotides containing the three bases thymine, cytosine, and guanine.
Topics: Base Sequence; Cross-Linking Reagents; Cytosine; DNA, Viral; Furocoumarins; Guanine; HIV; Hydrogen B | 1992 |
Synthesis of biologically active derivatives of D-glucosamine-4-phosphate and 1-thyminyl-D-glucosamine-4,6-disulfate.
Topics: Antiviral Agents; Glucosamine; Glucosephosphates; HIV; Thymine | 1990 |
Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif.
Topics: Adenine; Base Sequence; DNA; DNA, Viral; Guanine; HIV; Hydrogen Bonding; Models, Structural; Molecul | 1989 |
Synthesis and evaluation of a series of 1-(3-alkyl-2,3-dideoxy-alpha,beta-D-erythro-pentofuranosyl)thymines.
Topics: Acetylation; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, High Pressure Liqui | 1988 |