thymine has been researched along with Folic Acid Deficiency in 13 studies
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "If thymine was present in this medium, an unlimited exponential growth was possible." | 1.24 | Growth of Lactobacillus acidophilus in the absence of folic acid. ( Soska, J, 1966) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petering, HG | 1 |
| Delor, RA | 1 |
| Dreizen, S | 1 |
| McCredie, KB | 1 |
| Keating, MJ | 1 |
| Andersson, BS | 1 |
| Lutsiuk, MB | 1 |
| de Waard, H | 1 |
| Hoffbrand, AV | 1 |
| Pegg, AE | 1 |
| Koutts, J | 1 |
| Van der Weyden, MB | 2 |
| Cooper, M | 1 |
| Zittoun, J | 1 |
| Zittoun, R | 1 |
| Friedkin, M | 1 |
| Herbert, V | 3 |
| Tisman, G | 1 |
| Brenner, L | 1 |
| Waxman, S | 2 |
| Corcino, J | 1 |
| Soska, J | 1 |
| Rother, M | 1 |
| Firkin, BG | 1 |
| Metz, J | 1 |
| Kelly, A | 1 |
| Swett, VC | 1 |
3 reviews available for thymine and Folic Acid Deficiency
| Article | Year |
|---|---|
Folate metabolism.
Topics: Anemia, Sideroblastic; Coenzymes; DNA; FIGLU Test; Folic Acid; Folic Acid Antagonists; Folic Acid De | 1972 |
Thymidylate synthetase.
Topics: Animals; Binding Sites; Deoxyuridine; Drug Stability; Escherichia coli; Fluorouracil; Folic Acid Def | 1973 |
Aggravation or initiation of megaloblastosis by amino acids in the diet.
Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Defic | 1970 |
10 other studies available for thymine and Folic Acid Deficiency
| Article | Year |
|---|---|
Inability of Thymine and Adenine to Substitute for Pteroylglutamic Acid in the Folic Acid-deficient Rat.
Topics: Adenine; Animals; Folic Acid; Folic Acid Deficiency; Humans; Rats; Thymine | 1949 |
Nutritional deficiencies in patients receiving cancer chemotherapy.
Topics: Antineoplastic Agents; Cachexia; Folic Acid Deficiency; Humans; Hypoproteinemia; Methotrexate; Neopl | 1990 |
[Effect of folic acid, methotrexate and thymine on antibody synthesis].
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Erythrocytes; Folic Acid; Folic Acid Defici | 1970 |
[Effect of thymine and adenine in nutrition on folic-acid deficient rats].
Topics: Adenine; Animals; Female; Folic Acid Deficiency; Male; Methotrexate; Rats; Thymine | 1974 |
Base composition of normal and megaloblastic bone marrow DNA.
Topics: Adenine; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Cytidine; Cytosine; DNA; Folic Acid Def | 1972 |
Effect ot trimethoprim on folate metabolism in human bone marrow.
Topics: Adult; Anemia, Macrocytic; Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; Dep | 1973 |
The dU suppression test using 125 I-UdR to define biochemical megaloblastosis.
Topics: Anemia, Macrocytic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; In Vi | 1973 |
Growth of Lactobacillus acidophilus in the absence of folic acid.
Topics: Amino Acids; Folic Acid Deficiency; In Vitro Techniques; Lactobacillus acidophilus; Nucleosides; Pur | 1966 |
The metabolic significance of reduced serum B 12 in folate deficiency.
Topics: Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deoxyuridine; DNA; Folic Acid; Folic Acid Defic | 1972 |
Deranged DNA synthesis by bone marrow from vitamin B-12-deficient humans.
Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Female; Folic Acid; Folic Aci | 1968 |