thymine has been researched along with Disease Models, Animal in 16 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Interestingly, only CORT118335 completely prevented the HFD-induced weight gain and white fat deposition, whereas mifepristone showed no effect on body weight and modestly increased subcutaneous fat mass." | 3.83 | A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet. ( Antelmi, A; Armani, A; Caprio, M; Chlopicki, S; Cinti, F; Fabbri, A; Feraco, A; Hunt, H; Mammi, C; Marzolla, V; Maslak, E, 2016) |
| "However, its effect on oral squamous cell carcinoma (OSCC) is still unknown." | 1.62 | Efficacy of a Novel Oral Chemotherapeutic Agent, TAS-102, Against Human Oral Squamous Cell Carcinoma Cells. ( Ferdous, T; Harada, K; Mishima, K, 2021) |
| " We found that early accumulation of KARs occurs in the DA neurons of the parkinQ311X mouse, and that chronic administration of the KAR antagonist UBP310 prevents DA neuron loss." | 1.56 | Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity. ( Albanese, F; Bagnati, R; Cattaneo, S; Ciammola, A; Consalez, GG; Croci, L; Davoli, E; Di Fonzo, A; Mercatelli, D; Morari, M; Novello, S; Passafaro, M; Passoni, A; Regoni, M; Sassone, J; Serratto, GM; Taverna, S; Valtorta, F; Zanetti, L, 2020) |
| "In the present study, we used colorectal cancer xenografts to assess whether the efficacy of TAS-102 could be improved by combining it with bevacizumab, cetuximab or panitumumab." | 1.42 | Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts. ( Ishida, K; Matsuo, K; Nakagawa, F; Okabe, H; Sakamoto, K; Takechi, T; Tanaka, N; Tsukihara, H; Uchida, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, K | 1 |
| Ferdous, T | 1 |
| Mishima, K | 1 |
| Regoni, M | 1 |
| Cattaneo, S | 1 |
| Mercatelli, D | 1 |
| Novello, S | 1 |
| Passoni, A | 1 |
| Bagnati, R | 1 |
| Davoli, E | 1 |
| Croci, L | 1 |
| Consalez, GG | 1 |
| Albanese, F | 1 |
| Zanetti, L | 1 |
| Passafaro, M | 1 |
| Serratto, GM | 1 |
| Di Fonzo, A | 1 |
| Valtorta, F | 1 |
| Ciammola, A | 1 |
| Taverna, S | 1 |
| Morari, M | 1 |
| Sassone, J | 1 |
| Belcher, A | 1 |
| Zulfiker, AHM | 1 |
| Li, OQ | 1 |
| Yue, H | 1 |
| Gupta, AS | 1 |
| Li, W | 1 |
| Grosenbaugh, DK | 1 |
| Ross, BM | 1 |
| Wagley, P | 1 |
| Zanelli, SA | 1 |
| Qin, W | 1 |
| Lu, X | 1 |
| Lin, S | 1 |
| Foster, BL | 1 |
| Sheen, CR | 1 |
| Hatch, NE | 1 |
| Liu, J | 1 |
| Cory, E | 1 |
| Narisawa, S | 1 |
| Kiffer-Moreira, T | 1 |
| Sah, RL | 1 |
| Whyte, MP | 1 |
| Somerman, MJ | 1 |
| Millán, JL | 1 |
| Tsukihara, H | 1 |
| Nakagawa, F | 1 |
| Sakamoto, K | 1 |
| Ishida, K | 1 |
| Tanaka, N | 1 |
| Okabe, H | 1 |
| Uchida, J | 1 |
| Matsuo, K | 1 |
| Takechi, T | 1 |
| Ghosh, S | 1 |
| Canugovi, C | 1 |
| Yoon, JS | 1 |
| Wilson, DM | 1 |
| Croteau, DL | 1 |
| Mattson, MP | 1 |
| Bohr, VA | 1 |
| Mammi, C | 1 |
| Marzolla, V | 1 |
| Armani, A | 1 |
| Feraco, A | 1 |
| Antelmi, A | 1 |
| Maslak, E | 1 |
| Chlopicki, S | 1 |
| Cinti, F | 1 |
| Hunt, H | 1 |
| Fabbri, A | 1 |
| Caprio, M | 1 |
| Toye, AA | 1 |
| Moir, L | 1 |
| Hugill, A | 1 |
| Bentley, L | 1 |
| Quarterman, J | 1 |
| Mijat, V | 1 |
| Hough, T | 1 |
| Goldsworthy, M | 1 |
| Haynes, A | 1 |
| Hunter, AJ | 1 |
| Browne, M | 1 |
| Spurr, N | 1 |
| Cox, RD | 1 |
| Wang, X | 1 |
| Gattone, V | 1 |
| Harris, PC | 1 |
| Torres, VE | 1 |
| Gu, Y | 1 |
| Wang, L | 1 |
| Zhou, J | 1 |
| Guo, Q | 1 |
| Liu, N | 1 |
| Ding, Z | 1 |
| Li, L | 1 |
| Liu, X | 1 |
| An, J | 1 |
| Yan, G | 1 |
| Yao, L | 1 |
| Zhang, Z | 1 |
| Wang, YJ | 1 |
| Ho, YS | 1 |
| Lo, MJ | 1 |
| Lin, JK | 1 |
| Barbieri, S | 1 |
| Hofele, K | 1 |
| Wiederhold, KH | 1 |
| Probst, A | 1 |
| Mistl, C | 1 |
| Danner, S | 1 |
| Kauffmann, S | 1 |
| Sommer, B | 1 |
| Spooren, W | 1 |
| Tolnay, M | 1 |
| Bilbe, G | 1 |
| van der Putten, H | 1 |
| Rao, PM | 1 |
| Nagamine, Y | 1 |
| Roomi, MW | 1 |
| Rajalakshmi, S | 1 |
| Sarma, DS | 1 |
| Goldstein, G | 1 |
| Hofmann, WW | 1 |
1 review available for thymine and Disease Models, Animal
| Article | Year |
|---|---|
Mouse models of alpha-synucleinopathy and Lewy pathology. Alpha-synuclein expression in transgenic mice.
Topics: Adenine; alpha-Synuclein; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Humans; Lewy Bo | 2001 |
15 other studies available for thymine and Disease Models, Animal
| Article | Year |
|---|---|
Efficacy of a Novel Oral Chemotherapeutic Agent, TAS-102, Against Human Oral Squamous Cell Carcinoma Cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, | 2021 |
Pharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.
Topics: Alanine; Animals; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Female; GluK2 Kaina | 2020 |
Targeting Thymidine Phosphorylase With Tipiracil Hydrochloride Attenuates Thrombosis Without Increasing Risk of Bleeding in Mice.
Topics: Animals; Aspirin; Blood Platelets; Carotid Artery Thrombosis; Chlorocebus aethiops; COS Cells; Disea | 2021 |
The Role of Kainate Receptors in the Pathophysiology of Hypoxia-Induced Seizures in the Neonatal Mouse.
Topics: Alanine; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Electroencephalo | 2018 |
Programmable base editing in zebrafish using a modified CRISPR-Cas9 system.
Topics: Abnormalities, Multiple; Animals; Base Sequence; CRISPR-Cas Systems; Cytidine; Cytidine Deaminase; D | 2018 |
Periodontal Defects in the A116T Knock-in Murine Model of Odontohypophosphatasia.
Topics: Adenine; Alkaline Phosphatase; Alveolar Process; Animals; Biomechanical Phenomena; Bone Density; Bon | 2015 |
Efficacy of combination chemotherapy using a novel oral chemotherapeutic agent, TAS-102, together with bevacizumab, cetuximab, or panitumumab on human colorectal cancer xenografts.
Topics: Administration, Oral; Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocol | 2015 |
Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice.
Topics: Animals; Disease Models, Animal; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; End | 2015 |
A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Diet, High-Fat; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C5 | 2016 |
A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.
Topics: Adenine; Amino Acid Sequence; Amino Acid Substitution; Animals; Chromosome Mapping; Diabetes Mellitu | 2004 |
Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat.
Topics: Adenine; Animals; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Cyclic AMP; Disease Model | 2005 |
A naturally-occurring mutation in Cacna1f in a rat model of congenital stationary night blindness.
Topics: Adaptation, Ocular; Amino Acid Sequence; Animals; Calcium Channels; Cytosine; Dark Adaptation; Disea | 2008 |
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D | 1995 |
Orotic acid, a new promoter for experimental liver carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Arginine; Carcinogens; Diet; Disease Models, Animal; DNA; gamma-Glut | 1984 |
Experimental myasthenia gravis.
Topics: Animals; Antibody Formation; Antigens; Autoimmune Diseases; Cattle; Disease Models, Animal; Electrom | 1971 |