thymine has been researched along with Cockayne Syndrome in 3 studies
Cockayne Syndrome: A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Similar results were seen with a Cockayne syndrome B (CSB) cell line." | 2.41 | Factors influencing the removal of thymine glycol from DNA in gamma-irradiated human cells. ( Cooper, PK; Le, XC; Leadon, SA; Lee, J; Weinfeld, M; Xing, JZ, 2001) |
| "In contrast, Cockayne syndrome (CS) patients exhibit severe developmental and neurological defects, in addition to photosensitivity." | 1.33 | Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts. ( Hanawalt, PC; Spivak, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spivak, G | 1 |
| Hanawalt, PC | 1 |
| Weinfeld, M | 1 |
| Xing, JZ | 1 |
| Lee, J | 1 |
| Leadon, SA | 1 |
| Cooper, PK | 1 |
| Le, XC | 1 |
| Selzer, RR | 1 |
| Nyaga, S | 1 |
| Tuo, J | 1 |
| May, A | 1 |
| Muftuoglu, M | 1 |
| Christiansen, M | 1 |
| Citterio, E | 1 |
| Brosh, RM | 1 |
| Bohr, VA | 1 |
1 review available for thymine and Cockayne Syndrome
| Article | Year |
|---|---|
Factors influencing the removal of thymine glycol from DNA in gamma-irradiated human cells.
Topics: Animals; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, | 2001 |
2 other studies available for thymine and Cockayne Syndrome
| Article | Year |
|---|---|
Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblasts.
Topics: beta-Galactosidase; Cell Survival; Cells, Cultured; Cockayne Syndrome; DNA Damage; DNA Repair; DNA, | 2006 |
Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells.
Topics: Adenosine Triphosphatases; Amino Acid Motifs; Amino Acid Sequence; Apoptosis; Cell Extracts; Cell Li | 2002 |