Page last updated: 2024-10-20

thymine and Cancer of Skin

thymine has been researched along with Cancer of Skin in 11 studies

Research Excerpts

ExcerptRelevanceReference
"Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine."3.81Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. ( Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB, 2015)
"We tested 17 malignant mucosal melanomas of the head and neck for the thymine (T)-->adenine (A) missense mutation at nucleotide 1796 in the BRAF gene using direct sequencing and a newly developed assay that uses a novel primer extension method (Mutector assay)."3.72Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites. ( Begum, S; Cohen, Y; Esche, C; Goldenberg, D; Lavie, O; Rosenbaum, E; Sidransky, D; Westra, WH, 2004)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Lu, C1
Gutierrez-Bayona, NE1
Taylor, JS1
Premi, S1
Wallisch, S1
Mano, CM1
Weiner, AB1
Bacchiocchi, A1
Wakamatsu, K1
Bechara, EJ1
Halaban, R1
Douki, T1
Brash, DE1
RĂ¼nger, TM1
Cohen, Y1
Rosenbaum, E1
Begum, S1
Goldenberg, D1
Esche, C1
Lavie, O1
Sidransky, D1
Westra, WH1
Nishigori, C1
Arima, Y1
Matsumura, Y1
Matsui, M1
Miyachi, Y1
Laing, ME1
Dicker, P1
Moloney, FJ1
Ho, WL1
Murphy, GM1
Conlon, P1
Whitehead, AS1
Shields, DC1
Mills, KJ1
Reynolds, SH1
Smart, RC1
Robbins, JH1
Kraemer, KH1
Lutzner, MA1
Festoff, BW1
Coon, HG1
Heidelberger, C1
Ebner, H1

Reviews

1 review available for thymine and Cancer of Skin

ArticleYear
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Divisi

1970

Other Studies

10 other studies available for thymine and Cancer of Skin

ArticleYear
The effect of flanking bases on direct and triplet sensitized cyclobutane pyrimidine dimer formation in DNA depends on the dipyrimidine, wavelength and the photosensitizer.
    Nucleic acids research, 2021, 05-07, Volume: 49, Issue:8

    Topics: 3' Flanking Region; 5' Flanking Region; Base Sequence; Cytosine; DNA; Humans; Melanocytes; Mutagenes

2021
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes;

2015
C-->T transition mutations are not solely UVB-signature mutations, because they are also generated by UVA.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:9

    Topics: Animals; Carcinoma, Squamous Cell; Cells, Cultured; Cytosine; DNA; DNA Damage; DNA, Neoplasm; Mice;

2008
Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-15, Volume: 10, Issue:10

    Topics: Adenine; DNA; Exons; Head and Neck Neoplasms; Humans; Melanocytes; Melanoma; Models, Genetic; Mutage

2004
Impaired removal of 8-hydroxydeoxyguanosine induced by UVB radiation in naevoid basal cell carcinoma syndrome cells.
    The British journal of dermatology, 2005, Volume: 153 Suppl 2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Basal Cell Nevus Syndrome; Case-Control Studies; Cel

2005
Association of methylenetetrahydrofolate reductase polymorphism and the risk of squamous cell carcinoma in renal transplant patients.
    Transplantation, 2007, Jul-15, Volume: 84, Issue:1

    Topics: Alleles; Carcinoma, Squamous Cell; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Gu

2007
Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Clone Cells; Decanoic Acids; Digl

1993
[Molecular origin of the effects of light on nucleic acid metabolism].
    Folia haematologica (Leipzig, Germany : 1928), 1974, Volume: 101, Issue:5

    Topics: Animals; Bacteria; Bacteriophages; Cytosine; DNA; Humans; Methylene Blue; Mice; Nucleic Acid Renatur

1974
Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair.
    Annals of internal medicine, 1974, Volume: 80, Issue:2

    Topics: Adolescent; Adult; Autoradiography; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chemical Phenom

1974
[New possibilities in the treatment of epithelioma].
    Wiener klinische Wochenschrift, 1969, Nov-04, Volume: 81, Issue:46

    Topics: Animals; Fluorouracil; Humans; Precancerous Conditions; Rats; Skin Neoplasms; Thymine; Uracil

1969