thymine has been researched along with Cancer of Gastrointestinal Tract in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trifluridine/tipiracil is an oral chemotherapeutic agent recently approved for third-line treatment of chemorefractory metastatic colorectal cancer." | 2.58 | Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers. ( Cervantes, A; Moreno Vera, S; Peeters, M; Taieb, J, 2018) |
| " The thymidine analog trifluorothymidine (TFT) has been shown to bypass resistance pathways for 5FU derivatives (S-1, UFT, Xeloda) in model systems, while concurrent application with a thymidine phosphorylase inhibitor (TPI) increases the bioavailability of TFT, thereby potentiating the in vivo efficacy of TFT." | 2.44 | Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies. ( de Bruin, M; Emura, T; Fukushima, M; Peters, GJ; Temmink, OH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chakrabarti, S | 1 |
| Wintheiser, G | 1 |
| Tella, SH | 1 |
| Oxencis, C | 1 |
| Mahipal, A | 1 |
| Hernando-Cubero, J | 1 |
| Matos-García, I | 1 |
| Alonso-Orduña, V | 1 |
| Capdevila, J | 1 |
| Peeters, M | 1 |
| Cervantes, A | 1 |
| Moreno Vera, S | 1 |
| Taieb, J | 1 |
| Temmink, OH | 1 |
| Emura, T | 1 |
| de Bruin, M | 1 |
| Fukushima, M | 1 |
| Peters, GJ | 1 |
4 reviews available for thymine and Cancer of Gastrointestinal Tract
| Article | Year |
|---|---|
TAS-102: A resurrected novel Fluoropyrimidine with expanding role in the treatment of gastrointestinal malignancies.
Topics: Clinical Trials, Phase III as Topic; Drug Combinations; Gastrointestinal Neoplasms; Humans; Pyrrolid | 2021 |
The Role of Fluoropirimidines in Gastrointestinal Tumours: from the Bench to the Bed.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocol | 2017 |
Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Clinical Trials as Topic; | 2018 |
Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Clinical Trials as T | 2007 |