thymine has been researched along with Breast Neoplasms in 18 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that this polymorphism may modulate the cytotoxic effect of 5-fluorouracil (5FU) and methotrexate (MTX), two commonly used chemotherapeutic agents for colon and breast cancers, because the modes of action of 5FU and MTX are critically dependent on cellular composition of folates." | 7.72 | Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. ( Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z, 2004) |
| "Transgenic animal experiments suggest that increased expression of transforming growth factor beta1 (TGF-beta1) is protective against early tumor development, particularly in breast cancer." | 7.71 | Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures. ( Browner, WS; Cauley, J; Morin, PA; Saiz, R; Ziv, E, 2001) |
| " We hypothesized that this polymorphism may modulate the cytotoxic effect of 5-fluorouracil (5FU) and methotrexate (MTX), two commonly used chemotherapeutic agents for colon and breast cancers, because the modes of action of 5FU and MTX are critically dependent on cellular composition of folates." | 3.72 | Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate. ( Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z, 2004) |
| "Transgenic animal experiments suggest that increased expression of transforming growth factor beta1 (TGF-beta1) is protective against early tumor development, particularly in breast cancer." | 3.71 | Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures. ( Browner, WS; Cauley, J; Morin, PA; Saiz, R; Ziv, E, 2001) |
| "We found no difference in breast cancer risk between MTHFR 677 TT homozygotes and CC homozygotes (OR = 1." | 2.43 | Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk. ( Harbord, RM; Harris, R; Lewis, SJ; Smith, GD, 2006) |
| "A case-control study of 206 breast cancer patients and 262 controls was conducted in Iranian women." | 1.39 | Polymorphic CT dinucleotide repeat in the GATA3 gene and risk of breast cancer in Iranian women. ( Forousan, S; Manoochehr, T; Simin, H; Zakieh, A, 2013) |
| "In contrast, breast cancer patients with the variant allele at codon 677 (C/T or T/T) had improved survival, albeit not statistically significant, when compared to individuals with the common C/C genotype (HR = 0." | 1.33 | Association of MTHFR gene polymorphisms with breast cancer survival. ( Ambs, S; Boersma, BJ; Chanock, SJ; Goodman, JE; Howe, TM; Martin, DN; Mechanic, LE, 2006) |
| "The odds ratio of TT homozygotes for breast cancer was 0." | 1.32 | The common 677C>T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk. ( Krippl, P; Langsenlehner, U; Paulweber, B; Renner, W; Samonigg, H; Wascher, TC; Weitzer, W; Wolf, G; Yazdani-Biuki, B, 2003) |
| "The association between breast cancer risk and genetic polymorphisms of p53 at codon 72 (Arg72Pro) has been investigated by several studies, but the results are not consistent." | 1.32 | Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer. ( Hamajima, N; Hirose, K; Huang, XE; Iwata, H; Katsuda, N; Matsuo, K; Miura, S; Mizutani, M; Tajima, K; Tokudome, S; Xiang, J, 2003) |
| "All patients had a family history of tumors previously associated with A-T heterozygosity or homozygosity." | 1.29 | ATM mutations in cancer families. ( Croce, CM; Hammarström, L; Lindblom, A; Luo, L; Negrini, M; Vorechovský, I; Webster, AD, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roy, J | 1 |
| Kaake, M | 1 |
| Srinivasarao, M | 1 |
| Low, PS | 1 |
| Zakieh, A | 1 |
| Simin, H | 1 |
| Forousan, S | 1 |
| Manoochehr, T | 1 |
| Ribeiro, MP | 1 |
| Souza, SA | 1 |
| Lopes, FP | 1 |
| Rosado-de-Castro, PH | 1 |
| Fonseca, LM | 2 |
| Gutfilen, B | 3 |
| Suhasini, AN | 1 |
| Sommers, JA | 1 |
| Mason, AC | 1 |
| Voloshin, ON | 1 |
| Camerini-Otero, RD | 1 |
| Wold, MS | 1 |
| Brosh, RM | 1 |
| Benes, P | 1 |
| Jurajda, M | 1 |
| Zaloudík, J | 1 |
| Izakovicová-Hollá, L | 1 |
| Vácha, J | 1 |
| Langsenlehner, U | 1 |
| Krippl, P | 1 |
| Renner, W | 1 |
| Yazdani-Biuki, B | 1 |
| Wolf, G | 1 |
| Wascher, TC | 1 |
| Paulweber, B | 1 |
| Weitzer, W | 1 |
| Samonigg, H | 1 |
| Huang, XE | 1 |
| Hamajima, N | 1 |
| Katsuda, N | 1 |
| Matsuo, K | 1 |
| Hirose, K | 1 |
| Mizutani, M | 1 |
| Iwata, H | 1 |
| Miura, S | 1 |
| Xiang, J | 1 |
| Tokudome, S | 1 |
| Tajima, K | 1 |
| Sohn, KJ | 1 |
| Croxford, R | 1 |
| Yates, Z | 1 |
| Lucock, M | 1 |
| Kim, YI | 1 |
| Martin, DN | 1 |
| Boersma, BJ | 1 |
| Howe, TM | 1 |
| Goodman, JE | 1 |
| Mechanic, LE | 1 |
| Chanock, SJ | 1 |
| Ambs, S | 1 |
| Lewis, SJ | 1 |
| Harbord, RM | 1 |
| Harris, R | 1 |
| Smith, GD | 1 |
| Vorechovský, I | 1 |
| Luo, L | 1 |
| Lindblom, A | 1 |
| Negrini, M | 1 |
| Webster, AD | 1 |
| Croce, CM | 1 |
| Hammarström, L | 1 |
| Ziv, E | 1 |
| Cauley, J | 1 |
| Morin, PA | 1 |
| Saiz, R | 1 |
| Browner, WS | 1 |
| Rodrigues, E | 1 |
| Soraggi, R | 1 |
| Barbosa Da Fonseca, LH | 1 |
| Malette, P | 1 |
| Sampérez, S | 1 |
| Jouan, P | 1 |
| Tuchman, M | 1 |
| Stoeckeler, JS | 1 |
| Kiang, DT | 1 |
| O'Dea, RF | 1 |
| Ramnaraine, ML | 1 |
| Mirkin, BL | 1 |
| Wolberg, WH | 1 |
| Van Way, CW | 1 |
| Reynolds, VH | 1 |
1 review available for thymine and Breast Neoplasms
| Article | Year |
|---|---|
Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk.
Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Breast Neoplasms; Case-Control Studies; Cytosine; | 2006 |
1 trial available for thymine and Breast Neoplasms
| Article | Year |
|---|---|
Comparison of Tc-99m THY and Tc-99m MIBI scans for diagnosis of breast lesions.
Topics: Breast Diseases; Breast Neoplasms; Female; Humans; Mammography; Organotechnetium Compounds; Radionuc | 2001 |
16 other studies available for thymine and Breast Neoplasms
| Article | Year |
|---|---|
Targeted Tubulysin B Hydrazide Conjugate for the Treatment of Luteinizing Hormone-Releasing Hormone Receptor-Positive Cancers.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Drug Delivery Systems; Endometrial Neoplasms; Fema | 2018 |
Polymorphic CT dinucleotide repeat in the GATA3 gene and risk of breast cancer in Iranian women.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cytosine; | 2013 |
99mTc-thymine scintigraphy may be a promising method in the diagnosis of breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Breast Neoplasms; Female; Humans; Mammography; Middle Aged; | 2013 |
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.
Topics: Basic-Leucine Zipper Transcription Factors; Breast Neoplasms; DNA; DNA Adducts; DNA Damage; DNA Heli | 2009 |
C766T low-density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Biomarkers, Tumor; Breast Neoplasms; Cytosine; Female; Gene | 2003 |
The common 677C>T gene polymorphism of methylenetetrahydrofolate reductase gene is not associated with breast cancer risk.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma, Ductal, Breast; Case-Control Studies; C | 2003 |
Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer.
Topics: Adenine; Adult; Aged; Arginine; Breast Neoplasms; Carcinoma, Ductal; Case-Control Studies; Codon; Cy | 2003 |
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, T | 2004 |
Association of MTHFR gene polymorphisms with breast cancer survival.
Topics: Adenine; Black or African American; Breast Neoplasms; Cytosine; Female; Genotype; Humans; Methylenet | 2006 |
ATM mutations in cancer families.
Topics: Adenine; Alleles; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; C | 1996 |
Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures.
Topics: Aged; Amino Acid Substitution; Body Mass Index; Bone Density; Breast Neoplasms; Cytosine; Female; Ge | 2001 |
Preliminary observation of 99mTc-thymine imaging in breast neoplasms.
Topics: Adult; Biopsy; Breast Neoplasms; Female; Humans; Mammography; Middle Aged; Organotechnetium Compound | 2001 |
[Demonstration of pyrimidine nucleoside phosphorylases in breast cancer].
Topics: Breast Neoplasms; Chromatography, Ion Exchange; Cytosol; Humans; Pentosyltransferases; Pyrimidine Ph | 1989 |
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Fluorouracil; Humans; Male | 1985 |
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil.
Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chem | 1972 |
A new method for treatment of carcinoma of the breast and colon with 5-fluorouracil.
Topics: Adult; Aged; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Female; Fluorouraci | 1970 |