thymine has been researched along with Ataxia Telangiectasia in 3 studies
Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The capacity of whole cell sonicates of skin fibroblasts of normal individuals and patients with the autosomal recessive disease Ataxia telangiectasia (AT) to remove aerobic gamma-ray products of the 5,6-dihydroxydihydrothymine type (tgamma02) from exogenous DNA substrates was investigated." | 7.65 | Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts. ( Cerutti, PA; Remsen, JF, 1977) |
| "The capacity of whole cell sonicates of skin fibroblasts of normal individuals and patients with the autosomal recessive disease Ataxia telangiectasia (AT) to remove aerobic gamma-ray products of the 5,6-dihydroxydihydrothymine type (tgamma02) from exogenous DNA substrates was investigated." | 3.65 | Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts. ( Cerutti, PA; Remsen, JF, 1977) |
| "All patients had a family history of tumors previously associated with A-T heterozygosity or homozygosity." | 1.29 | ATM mutations in cancer families. ( Croce, CM; Hammarström, L; Lindblom, A; Luo, L; Negrini, M; Vorechovský, I; Webster, AD, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vorechovský, I | 1 |
| Luo, L | 1 |
| Lindblom, A | 1 |
| Negrini, M | 1 |
| Webster, AD | 1 |
| Croce, CM | 1 |
| Hammarström, L | 1 |
| Cerutti, P | 1 |
| Shinohara, K | 1 |
| Remsen, J | 1 |
| Remsen, JF | 1 |
| Cerutti, PA | 1 |
1 review available for thymine and Ataxia Telangiectasia
| Article | Year |
|---|---|
Repair of DNA damage induced by ionizing radiation and benzo[a]pyrene in mammalian cells.
Topics: Animals; Ataxia Telangiectasia; Benzopyrenes; Cell Line; DNA; DNA Repair; DNA, Neoplasm; Embryo, Mam | 1977 |
2 other studies available for thymine and Ataxia Telangiectasia
| Article | Year |
|---|---|
ATM mutations in cancer families.
Topics: Adenine; Alleles; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; C | 1996 |
Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts.
Topics: Aerobiosis; Ataxia Telangiectasia; Cell-Free System; DNA; DNA Repair; DNA, Viral; Fibroblasts; Gamma | 1977 |