thymidine-glycol and Neoplasms

thymidine-glycol has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for thymidine-glycol and Neoplasms

ArticleYear
Oxidative damage to DNA: levels of thymine glycol and thymidine glycol in neoplastic human urines.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    We have measured the levels of thymine glycol (TG) and thymidine glycol (dTG) in human urine, using an HPLC method. The results show that all 30 specimens examined (including 10 non-neoplastic and 20 neoplastic human urines) contained significant amounts of TG and dTG, average levels (mean +/- SEM) were 0.376 +/- 0.026 and 0.138 +/- 0.009 nmol/kg body weight/day respectively. The average levels of TG and dTG were 0.435 +/- 0.038 and 0.164 +/- 0.017 nmol/kg body weight/day in 10 healthy human urine specimens and 0.347 +/- 0.035 and 0.125 +/- 0.010 nmol/kg body weight/day in 20 neoplastic human urine specimens respectively. No significant differences were found between female and male as well as between the non-neoplastic and neoplastic human urine specimens. There were also wide interindividual variations, which were not age-dependent.

    Topics: Adolescent; Adult; Aged; DNA Damage; DNA Repair; Female; Humans; Male; Middle Aged; Neoplasms; Oxidation-Reduction; Thymidine; Thymine

1993