thymidine has been researched along with Vaccinia in 23 studies
Vaccinia: The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antiviral activities and nucleoside metabolism were determined in C127I mouse, LLC-MK2 monkey, and A549 human cells infected with thymidine-kinase-containing and -deficient (TK+ and TK-) vaccinia (WR strain) viruses." | 7.74 | Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus. ( Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF, 2008) |
| "The efficacy of trifluorothymidine was compared with idoxuridine on a blind basis by noting the effect of topical administration of the drugs on the severity of vaccinial keratitis induced in rabbits." | 7.65 | Treatment of Vaccinial keratitis with trifluorothymidine. ( Hyndiuk, RA; Leibsohn, JM; Seideman, S, 1976) |
| " treatment regimens with (N)-MCT were directly compared during a vaccinia virus (IHD strain) infection, indicating that the nucleoside has good oral bioavailability in mice." | 5.34 | Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus. ( Glazer, RI; Hurst, BL; Rahman, A; Sidwell, RW; Smee, DF; Wong, MH, 2007) |
| "Antiviral activities and nucleoside metabolism were determined in C127I mouse, LLC-MK2 monkey, and A549 human cells infected with thymidine-kinase-containing and -deficient (TK+ and TK-) vaccinia (WR strain) viruses." | 3.74 | Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus. ( Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF, 2008) |
| "The efficacy of trifluorothymidine was compared with idoxuridine on a blind basis by noting the effect of topical administration of the drugs on the severity of vaccinial keratitis induced in rabbits." | 3.65 | Treatment of Vaccinial keratitis with trifluorothymidine. ( Hyndiuk, RA; Leibsohn, JM; Seideman, S, 1976) |
| "Vaccinia virus which had its DNA labeled with thymidine-H(3) was purified and used as inoculum for L cells growing in suspension." | 3.64 | The uptake and development of vaccinia virus in strain L cells followed with labeled viral deoxyribonucleic acid. ( DALES, S, 1963) |
| " treatment regimens with (N)-MCT were directly compared during a vaccinia virus (IHD strain) infection, indicating that the nucleoside has good oral bioavailability in mice." | 1.34 | Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus. ( Glazer, RI; Hurst, BL; Rahman, A; Sidwell, RW; Smee, DF; Wong, MH, 2007) |
| "Thymidine kinase was synthesized in amounts that exceeded those found in untreated, infected cells." | 1.25 | Initiation of vaccinia virus infection in actinomycin D-pretreated cells. ( Magee, WE; Miller, OV, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (82.61) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smee, DF | 3 |
| Humphreys, DE | 1 |
| Hurst, BL | 2 |
| Barnard, DL | 1 |
| DALES, S | 1 |
| KIT, S | 7 |
| DUBBS, DR | 6 |
| HSU, TC | 1 |
| PIEKARSKI, LJ | 2 |
| VALLADARES, Y | 1 |
| MUNYON, W | 1 |
| Wandersee, MK | 1 |
| Bailey, KW | 1 |
| Wong, MH | 2 |
| Chu, CK | 1 |
| Gadthula, S | 1 |
| Sidwell, RW | 3 |
| Glazer, RI | 1 |
| Rahman, A | 1 |
| Prichard, MN | 1 |
| Kern, ER | 1 |
| Quenelle, DC | 1 |
| Keith, KA | 1 |
| Moyer, RW | 1 |
| Turner, PC | 1 |
| Hyndiuk, RA | 1 |
| Seideman, S | 1 |
| Leibsohn, JM | 1 |
| Hutt, LM | 1 |
| De Clercq, E | 1 |
| Darzynkiewicz, E | 1 |
| Shugar, D | 1 |
| Takeshita, M | 1 |
| Horwitz, SB | 1 |
| Grollman, AP | 1 |
| Sakaue, Y | 1 |
| Kato, S | 2 |
| Griscelli, C | 1 |
| Revillard, JP | 1 |
| Betuel, H | 1 |
| Herzog, C | 1 |
| Touraine, JL | 1 |
| Allen, LB | 1 |
| Mantani, M | 1 |
| Kaufmann, HE | 1 |
| Magee, WE | 1 |
| Miller, OV | 1 |
| Zhdanov, VM | 1 |
| Kozlova, IA | 1 |
| Melnikova, LA | 1 |
| Peterson, OP | 1 |
23 other studies available for thymidine and Vaccinia
| Article | Year |
|---|---|
Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; | 2008 |
The uptake and development of vaccinia virus in strain L cells followed with labeled viral deoxyribonucleic acid.
Topics: Autoradiography; Cell Membrane; Cytoplasm; DNA; DNA, Viral; Research; Thymidine; Tissue Culture Tech | 1963 |
Biochemistry of vaccinia-infected mouse fibroblasts (strain L-M). III. Radioautographic and biochemical studies of thymidine-H3 uptake into DNA of L-M cells and rabbit cells in primary culture.
Topics: Animals; DNA; Fibroblasts; Mice; Rabbits; Thymidine; Vaccinia; Vaccinia virus; Virus Cultivation | 1963 |
BIOCHEMISTRY OF VACCINIA-INFECTED MOUSE FIBROBLASTS (STRAIN L-M). IV. 3H-THYMIDINE UPTAKE INTO DNA OF CELLS EXPOSED TO COLD SHOCK.
Topics: Autoradiography; Cold Temperature; DNA; Fibroblasts; Mice; Research; Thymidine; Tissue Culture Techn | 1963 |
EFFECTS OF 5-FLUOROURACIL, ACTINOMYCIN D AND MITOMYCIN C ON THE INDUCTION OF THYMIDINE KINASE BY VACCINIA-INFECTED L-CELLS.
Topics: Dactinomycin; DNA; DNA, Viral; Enzyme Inhibitors; Floxuridine; Fluorouracil; Metabolism; Mice; Mitom | 1963 |
ISOLATION AND PROPERTIES OF VACCINIA MUTANTS DEFICIENT IN THYMIDINE KINASE-INDUCING ACTIVITY.
Topics: Autoradiography; Clone Cells; DNA; DNA, Viral; Fibroblasts; Mice; Mutation; Nucleosides; Pharmacolog | 1964 |
EFFECTS OF AGE OF CULTURE AND VACCINIA INFECTION ON URIDINE KINASE ACTIVITY OF L-CELLS.
Topics: Alanine; Animals; DNA; DNA, Viral; L Cells; Mice; Nucleosides; Phosphotransferases; Research; RNA; R | 1964 |
INHIBITION OF THYMIDINE KINASE FORMATION IN LM (TK-) CELLS SIMULTANEOUSLY INFECTED WITH VACCINIA AND A THYMIDINE KINASELESS VACCINIA MUTANT.
Topics: Deoxyuridine; Enzyme Inhibitors; Fibroblasts; Herpesviridae; Metabolism; Mutation; Research; RNA; RN | 1965 |
Enhanced thymidine phosphorylating activity of mouse fibroblasts (strain LM) following vaccinia infection.
Topics: Animals; Connective Tissue; DNA; Fibroblasts; Mice; Phosphorylation; RNA; Thymidine; Vaccinia | 1962 |
Cell line dependency for antiviral activity and in vivo efficacy of N-methanocarbathymidine against orthopoxvirus infections in mice.
Topics: Animals; Antiviral Agents; Cell Line; Cowpox; Cowpox virus; Humans; Mice; Mice, Inbred BALB C; Rabbi | 2007 |
Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Injections, Intraperitoneal; M | 2007 |
Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine.
Topics: Animals; Antiviral Agents; Female; Green Fluorescent Proteins; Humans; Mice; Mice, Inbred BALB C; Py | 2008 |
Treatment of Vaccinial keratitis with trifluorothymidine.
Topics: Animals; Corneal Opacity; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Idoxuridin | 1976 |
The immune response to infection with vaccinia virus in mice. II. Appearance of hypersensitivity, production of macrophage migration inhibitory factor and transformation of spleen cells in response to virus antigens.
Topics: Animals; Antigens, Viral; Cell Migration Inhibition; Cells, Cultured; Female; Hypersensitivity; Immu | 1975 |
Antiviral activity of O'-alkylated derivatives of cytosine arabinoside.
Topics: Alkylation; Animals; Antiviral Agents; Cells, Cultured; Cytarabine; Cytopathogenic Effect, Viral; DN | 1975 |
Bleomycin, an inhibitor of vaccinia virus replication.
Topics: Animals; Antiviral Agents; Bleomycin; Centrifugation, Zonal; DNA; DNA-Directed RNA Polymerases; DNA, | 1974 |
Autoradiographic studies on the sites of protein and RNA syntheses in poxvirus-infected cells.
Topics: Amnion; Animals; Autoradiography; Cattle; Cell Line; Culture Media; Cytoplasm; Humans; Inclusion Bod | 1974 |
Transfer factor therapy in immuno-deficiencies.
Topics: Agammaglobulinemia; Antigens; Ataxia Telangiectasia; Candida; Candidiasis, Cutaneous; Hypersensitivi | 1973 |
Target-organ treatment of neurotropic virus diseases: efficacy as a chemotherapy tool and comparison of activity of adenine arabinoside, cytosine arabinoside, idoxuridine, and trifluorothymidine.
Topics: Adenine; Animals; Antiviral Agents; Arabinose; Brain; Cytarabine; Fluorine; Herpes Simplex; Idoxurid | 1972 |
Virus multiplication in culture cells synchronized by excess thymidine treatment. 3. Effect of viral DNA synthesis of cowpox virus upon the mitotic phase of FL cells.
Topics: Amnion; Autoradiography; Cell Line; Colchicine; DNA, Viral; Fluorescent Antibody Technique; Humans; | 1971 |
In vivo studies with antiviral agents.
Topics: Animals; Bromodeoxyuridine; Cytarabine; Idoxuridine; Keratitis; Keratitis, Dendritic; Rabbits; Thymi | 1965 |
Initiation of vaccinia virus infection in actinomycin D-pretreated cells.
Topics: Dactinomycin; DNA; DNA Nucleotidyltransferases; DNA, Viral; HeLa Cells; Humans; RNA; Thymidine; Thym | 1968 |
Synthesis of DNA and protein in cells infected with vaccinia virus.
Topics: Alanine; Autoradiography; Cell Nucleus; Culture Techniques; Cytoplasm; DNA; HeLa Cells; Protein Bios | 1966 |