thymidine and Sclerosis, Systemic studies

thymidine and Sclerosis, Systemic

thymidine has been researched along with Sclerosis, Systemic in 23 studies

Research Excerpts

Excerpt	Relevance	Reference
"Sera from 29 patients with systemic sclerosis and 30 normal controls were examined for their effect on prostacyclin release by human umbilical vein endothelial cells during periods of response of 15 min and 72 h and for their effect on endothelial growth and 3H-thymidine uptake during a 72-h culture period."	1.28	Prostacyclin production by human umbilical vein endothelium in response to serum from patients with systemic sclerosis. ( Greaves, M; Holt, CM; Hughes, P; Lindsey, N; Moult, J; Rowell, NR, 1989)
"Sera from patients with progressive systemic sclerosis were compared with sera from normal individuals and from patients with other connective tissue diseases for cytotoxic effects on cultured human cells."	1.27	Cytotoxicity of sera from patients with scleroderma. Effects on human endothelial cells and fibroblasts in culture. ( Cohen, S; Hurd, E; Johnson, AR, 1983)

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (69.57)	18.7374
1990's	6 (26.09)	18.2507
2000's	1 (4.35)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

16 (69.57)

18.7374

1990's

6 (26.09)

18.2507

2000's

1 (4.35)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Kazandjian, S	1
Fiessinger, JN	1
Camilleri, JP	1
Dadoune, JP	1
Housset, E	1
Kahaleh, MB	3
Leroy, EC	2
Summers, GD	1
Weiss, JB	1
Jayson, MI	1
Cohen, S	1
Johnson, AR	1
Hurd, E	1
Bryckaert, M	1
Fontenay, M	1
Lioté, F	1
Bellucci, S	1
Carriou, R	1
Tobelem, G	1
Kikuchi, K	1
Kadono, T	1
Sato, S	1
Tamaki, K	1
Takehara, K	1
Denton, CP	1
Xu, S	1
Welsh, KI	1
Pearson, JD	1
Black, CM	1
Matucci-Cerinic, M	1
Iannone, F	1
Carossino, A	1
Pignone, A	1
Leoncini, G	1
Generini, S	1
Lapadula, G	1
Cagnoni, M	1
Ohtsuka, T	1
Koibuchi, N	1
Sakai, H	1
Yamakage, A	1
Yamazaki, S	1
Alarcón-Segovia, D	1
Fishbein, E	1
García-Ortigoza, E	1
Estrada-Parra, S	1
Sherer, GK	1
Krieg, T	1
Hörlein, D	1
Wiestner, M	1
Müller, PK	1
Fleischmajer, R	1
Perlish, JS	1
Hirt, A	1
Wagner, HP	1
Majewski, S	1
Błaszczyk, M	1
Jabłonska, S	1
Rudnicka, L	1
Waşik, M	1
Skiendzielewska, A	1
Makieła, B	1
Holt, CM	1
Moult, J	1
Lindsey, N	1
Hughes, P	1
Greaves, M	1
Rowell, NR	1
Abakumova, OIu	1
Kutsenko, NG	1
Panasiuk, AF	1
Tamura, T	1
Ishikawa, H	1
Winkelstein, A	1
Rodnan, GP	1
Heilman, JD	1
Currie, S	2
Saunders, M	2
Knowles, M	2
Brown, AE	1
Hedberg, H	1
Källén, B	1
Löw, B	1
Nilsson, O	1

Studies

Kazandjian, S

Fiessinger, JN

Camilleri, JP

Dadoune, JP

Housset, E

Kahaleh, MB

Leroy, EC

Summers, GD

Weiss, JB

Jayson, MI

Cohen, S

Johnson, AR

Hurd, E

Bryckaert, M

Fontenay, M

Lioté, F

Bellucci, S

Carriou, R

Tobelem, G

Kikuchi, K

Kadono, T

Sato, S

Tamaki, K

Takehara, K

Denton, CP

Xu, S

Welsh, KI

Pearson, JD

Black, CM

Matucci-Cerinic, M

Iannone, F

Carossino, A

Pignone, A

Leoncini, G

Generini, S

Lapadula, G

Cagnoni, M

Ohtsuka, T

Koibuchi, N

Sakai, H

Yamakage, A

Yamazaki, S

Alarcón-Segovia, D

Fishbein, E

García-Ortigoza, E

Estrada-Parra, S

Sherer, GK

Krieg, T

Hörlein, D

Wiestner, M

Müller, PK

Fleischmajer, R

Perlish, JS

Hirt, A

Wagner, HP

Majewski, S

Błaszczyk, M

Jabłonska, S

Rudnicka, L

Waşik, M

Skiendzielewska, A

Makieła, B

Holt, CM

Moult, J

Lindsey, N

Hughes, P

Greaves, M

Rowell, NR

Abakumova, OIu

Kutsenko, NG

Panasiuk, AF

Tamura, T

Ishikawa, H

Winkelstein, A

Rodnan, GP

Heilman, JD

Currie, S

Saunders, M

Knowles, M

Brown, AE

Hedberg, H

Källén, B

Löw, B

Nilsson, O

Other Studies

23 other studies available for thymidine and Sclerosis, Systemic

Article	Year
Endothelial cell renewal in skin of patients with progressive systemic sclerosis (PSS): an in vitro autoradiographic study. Acta dermato-venereologica, 1982, Volume: 62, Issue:5 Topics: Adult; Aged; Autoradiography; Biopsy; Endothelium; Female; Forearm; Humans; In Vitro Techniques; Mal	1982
Endothelial injury in scleroderma. A protease mechanism. The Journal of laboratory and clinical medicine, 1983, Volume: 101, Issue:4 Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride	1983
Failure of sera from patients with scleroderma to exhibit cytotoxicity towards human umbilical vein endothelial cells. Rheumatology international, 1984, Volume: 5, Issue:1 Topics: Adenosine Triphosphate; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytotoxicity,	1984
Cytotoxicity of sera from patients with scleroderma. Effects on human endothelial cells and fibroblasts in culture. Arthritis and rheumatism, 1983, Volume: 26, Issue:2 Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Scleroderma, Systemic; Thymidine	1983
Increased mitogenic activity of scleroderma serum: inhibitory effect of human recombinant interferon-gamma. Annals of the rheumatic diseases, 1994, Volume: 53, Issue:11 Topics: Adult; beta-Thromboglobulin; Cells, Cultured; CREST Syndrome; Dose-Response Relationship, Drug; Fema	1994
Impaired growth response to endothelin-1 in scleroderma fibroblasts. Biochemical and biophysical research communications, 1995, Feb-15, Volume: 207, Issue:2 Topics: Biopsy; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Endothelins; Endothelium,	1995
Scleroderma fibroblast phenotype is modulated by endothelial cell co-culture. The Journal of rheumatology, 1996, Volume: 23, Issue:4 Topics: Adult; Cell Count; Cell Division; Cell Transformation, Viral; Cells, Cultured; Coculture Techniques;	1996
Discrepant expression of neprilysin on fibroblasts in diffuse systemic sclerosis. The Journal of rheumatology, 1999, Volume: 26, Issue:2 Topics: Cell Division; Cell Membrane; Cells, Cultured; Fibroblasts; Flow Cytometry; Humans; Intracellular Fl	1999
Simultaneous analysis of [3H]-thymidine uptake and alpha 1(I) procollagen mRNA expression in systemic sclerosis skin fibroblasts--an in situ hybridization study. Archives of dermatological research, 2000, Volume: 292, Issue:5 Topics: Aged; Autoradiography; Cells, Cultured; DNA; Humans; In Situ Hybridization; Middle Aged; Procollagen	2000
Uracil-specific anti-R.N.A. antibodies in scleroderma. Lancet (London, England), 1975, Feb-15, Volume: 1, Issue:7903 Topics: Adenosine; Adenosine Monophosphate; Animals; Antibodies; Cattle; Cross Reactions; Cytidine; Cytosine	1975
Endothelial injury in scleroderma. The Journal of experimental medicine, 1979, Jun-01, Volume: 149, Issue:6 Topics: Adult; Cells, Cultured; Endothelium; Fibroblasts; Humans; Male; Muscle, Smooth; Raynaud Disease; Rhe	1979
Aminoterminal extension peptides from type I procollagen normalize excessive collagen synthesis of scleroderma fibroblasts. Archives of dermatological research, 1978, Nov-10, Volume: 263, Issue:2 Topics: Collagen; Culture Techniques; Fibroblasts; Humans; Peptide Termination Factors; Procollagen; Sclerod	1978
[3H]Thymidine labeling of dermal endothelial cells in scleroderma. The Journal of investigative dermatology, 1977, Volume: 69, Issue:4 Topics: Adult; Autoradiography; Capillaries; Endothelium; Female; Humans; Male; Middle Aged; Scleroderma, Lo	1977
Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man. Cell and tissue kinetics, 1975, Volume: 8, Issue:5 Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Fem	1975
Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action. Arthritis and rheumatism, 1991, Volume: 34, Issue:8 Topics: Cold Temperature; Collagen; Endothelins; Endothelium, Vascular; Fibroblasts; Humans; Proteins; Radio	1991
Cytotoxic effects of sera from patients with systemic scleroderma: comparison of three different in vitro methods. Rheumatology international, 1990, Volume: 10, Issue:2 Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Chromium; Chromium Radioisotopes; Cytotoxicity Tests, I	1990
Prostacyclin production by human umbilical vein endothelium in response to serum from patients with systemic sclerosis. British journal of rheumatology, 1989, Volume: 28, Issue:3 Topics: Adult; Aged; Cell Division; Endothelium, Vascular; Epoprostenol; Female; Humans; Male; Middle Aged;	1989
[The regulation of DNA synthesis by fibronectin and its proteolytic products in the skin fibroblasts of healthy donors and patients with systemic scleroderma and rheumatoid arthritis]. Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:12 Topics: Arthritis, Rheumatoid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Fibronec	1989
Clinical significance of lymphocyte responsiveness to scleroderma-inducing glycosaminoglycan-associated antigen in systemic scleroderma. Dermatologica, 1985, Volume: 171, Issue:6 Topics: Adolescent; Adult; Aged; DNA Replication; Female; Humans; Lymphocyte Activation; Lymphocytes; Male;	1985
Cellular immunity in progressive systemic sclerosis (scleroderma). Annals of the rheumatic diseases, 1972, Volume: 31, Issue:2 Topics: Antigens; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lectins; Lymphocyte Activation; Lym	1972
Immunological aspects of polymyositis. The in vitro activity of lymphocytes on incubation with muscle antigen and with muscle cultures. The Quarterly journal of medicine, 1971, Volume: 40, Issue:157 Topics: Adolescent; Adult; Aged; Animals; Antigens; Antilymphocyte Serum; Child, Preschool; Culture Techniqu	1971
Immunological aspects of systemic sclerosis in vitro activity of lymphocytes from patients with the disorder. The British journal of dermatology, 1971, Volume: 84, Issue:5 Topics: Adult; Animals; Antigens; Biopsy; Collagen; Culture Techniques; Cytotoxicity Tests, Immunologic; Der	1971
Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides. Clinical and experimental immunology, 1971, Volume: 9, Issue:2 Topics: Arthritis; Arthritis, Rheumatoid; Culture Techniques; Humans; Leukocytes; Lymphocyte Activation; Mit	1971

Article

Year

Endothelial cell renewal in skin of patients with progressive systemic sclerosis (PSS): an in vitro autoradiographic study.

Acta dermato-venereologica, 1982, Volume: 62, Issue:5

Topics: Adult; Aged; Autoradiography; Biopsy; Endothelium; Female; Forearm; Humans; In Vitro Techniques; Mal

1982

Endothelial injury in scleroderma. A protease mechanism.

The Journal of laboratory and clinical medicine, 1983, Volume: 101, Issue:4

Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride

1983

Failure of sera from patients with scleroderma to exhibit cytotoxicity towards human umbilical vein endothelial cells.

Rheumatology international, 1984, Volume: 5, Issue:1

Topics: Adenosine Triphosphate; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytotoxicity,

1984

Cytotoxicity of sera from patients with scleroderma. Effects on human endothelial cells and fibroblasts in culture.

Arthritis and rheumatism, 1983, Volume: 26, Issue:2

Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Scleroderma, Systemic; Thymidine

1983

Increased mitogenic activity of scleroderma serum: inhibitory effect of human recombinant interferon-gamma.

Annals of the rheumatic diseases, 1994, Volume: 53, Issue:11

Topics: Adult; beta-Thromboglobulin; Cells, Cultured; CREST Syndrome; Dose-Response Relationship, Drug; Fema

1994

Impaired growth response to endothelin-1 in scleroderma fibroblasts.

Biochemical and biophysical research communications, 1995, Feb-15, Volume: 207, Issue:2

Topics: Biopsy; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Endothelins; Endothelium,

1995

Scleroderma fibroblast phenotype is modulated by endothelial cell co-culture.

The Journal of rheumatology, 1996, Volume: 23, Issue:4

Topics: Adult; Cell Count; Cell Division; Cell Transformation, Viral; Cells, Cultured; Coculture Techniques;

1996

Discrepant expression of neprilysin on fibroblasts in diffuse systemic sclerosis.

The Journal of rheumatology, 1999, Volume: 26, Issue:2

Topics: Cell Division; Cell Membrane; Cells, Cultured; Fibroblasts; Flow Cytometry; Humans; Intracellular Fl

1999

Simultaneous analysis of [3H]-thymidine uptake and alpha 1(I) procollagen mRNA expression in systemic sclerosis skin fibroblasts--an in situ hybridization study.

Archives of dermatological research, 2000, Volume: 292, Issue:5

Topics: Aged; Autoradiography; Cells, Cultured; DNA; Humans; In Situ Hybridization; Middle Aged; Procollagen

2000

Uracil-specific anti-R.N.A. antibodies in scleroderma.

Lancet (London, England), 1975, Feb-15, Volume: 1, Issue:7903

Topics: Adenosine; Adenosine Monophosphate; Animals; Antibodies; Cattle; Cross Reactions; Cytidine; Cytosine

1975

Endothelial injury in scleroderma.

The Journal of experimental medicine, 1979, Jun-01, Volume: 149, Issue:6

Topics: Adult; Cells, Cultured; Endothelium; Fibroblasts; Humans; Male; Muscle, Smooth; Raynaud Disease; Rhe

1979

Aminoterminal extension peptides from type I procollagen normalize excessive collagen synthesis of scleroderma fibroblasts.

Archives of dermatological research, 1978, Nov-10, Volume: 263, Issue:2

Topics: Collagen; Culture Techniques; Fibroblasts; Humans; Peptide Termination Factors; Procollagen; Sclerod

1978

[3H]Thymidine labeling of dermal endothelial cells in scleroderma.

The Journal of investigative dermatology, 1977, Volume: 69, Issue:4

Topics: Adult; Autoradiography; Capillaries; Endothelium; Female; Humans; Male; Middle Aged; Scleroderma, Lo

1977

Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man.

Cell and tissue kinetics, 1975, Volume: 8, Issue:5

Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Fem

1975

Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action.

Arthritis and rheumatism, 1991, Volume: 34, Issue:8

Topics: Cold Temperature; Collagen; Endothelins; Endothelium, Vascular; Fibroblasts; Humans; Proteins; Radio

1991

Cytotoxic effects of sera from patients with systemic scleroderma: comparison of three different in vitro methods.

Rheumatology international, 1990, Volume: 10, Issue:2

Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Chromium; Chromium Radioisotopes; Cytotoxicity Tests, I

1990

Prostacyclin production by human umbilical vein endothelium in response to serum from patients with systemic sclerosis.

British journal of rheumatology, 1989, Volume: 28, Issue:3

Topics: Adult; Aged; Cell Division; Endothelium, Vascular; Epoprostenol; Female; Humans; Male; Middle Aged;

1989

[The regulation of DNA synthesis by fibronectin and its proteolytic products in the skin fibroblasts of healthy donors and patients with systemic scleroderma and rheumatoid arthritis].

Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:12

Topics: Arthritis, Rheumatoid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Fibronec

1989

Clinical significance of lymphocyte responsiveness to scleroderma-inducing glycosaminoglycan-associated antigen in systemic scleroderma.

Dermatologica, 1985, Volume: 171, Issue:6

Topics: Adolescent; Adult; Aged; DNA Replication; Female; Humans; Lymphocyte Activation; Lymphocytes; Male;

1985

Cellular immunity in progressive systemic sclerosis (scleroderma).

Annals of the rheumatic diseases, 1972, Volume: 31, Issue:2

Topics: Antigens; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lectins; Lymphocyte Activation; Lym

1972

Immunological aspects of polymyositis. The in vitro activity of lymphocytes on incubation with muscle antigen and with muscle cultures.

The Quarterly journal of medicine, 1971, Volume: 40, Issue:157

Topics: Adolescent; Adult; Aged; Animals; Antigens; Antilymphocyte Serum; Child, Preschool; Culture Techniqu

1971

Immunological aspects of systemic sclerosis in vitro activity of lymphocytes from patients with the disorder.

The British journal of dermatology, 1971, Volume: 84, Issue:5

Topics: Adult; Animals; Antigens; Biopsy; Collagen; Culture Techniques; Cytotoxicity Tests, Immunologic; Der

1971

Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides.

Clinical and experimental immunology, 1971, Volume: 9, Issue:2

Topics: Arthritis; Arthritis, Rheumatoid; Culture Techniques; Humans; Leukocytes; Lymphocyte Activation; Mit

1971