thymidine has been researched along with Scleroderma, Systemic in 23 studies
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sera from 29 patients with systemic sclerosis and 30 normal controls were examined for their effect on prostacyclin release by human umbilical vein endothelial cells during periods of response of 15 min and 72 h and for their effect on endothelial growth and 3H-thymidine uptake during a 72-h culture period." | 1.28 | Prostacyclin production by human umbilical vein endothelium in response to serum from patients with systemic sclerosis. ( Greaves, M; Holt, CM; Hughes, P; Lindsey, N; Moult, J; Rowell, NR, 1989) |
| "Sera from patients with progressive systemic sclerosis were compared with sera from normal individuals and from patients with other connective tissue diseases for cytotoxic effects on cultured human cells." | 1.27 | Cytotoxicity of sera from patients with scleroderma. Effects on human endothelial cells and fibroblasts in culture. ( Cohen, S; Hurd, E; Johnson, AR, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (69.57) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kazandjian, S | 1 |
| Fiessinger, JN | 1 |
| Camilleri, JP | 1 |
| Dadoune, JP | 1 |
| Housset, E | 1 |
| Kahaleh, MB | 3 |
| Leroy, EC | 2 |
| Summers, GD | 1 |
| Weiss, JB | 1 |
| Jayson, MI | 1 |
| Cohen, S | 1 |
| Johnson, AR | 1 |
| Hurd, E | 1 |
| Bryckaert, M | 1 |
| Fontenay, M | 1 |
| Lioté, F | 1 |
| Bellucci, S | 1 |
| Carriou, R | 1 |
| Tobelem, G | 1 |
| Kikuchi, K | 1 |
| Kadono, T | 1 |
| Sato, S | 1 |
| Tamaki, K | 1 |
| Takehara, K | 1 |
| Denton, CP | 1 |
| Xu, S | 1 |
| Welsh, KI | 1 |
| Pearson, JD | 1 |
| Black, CM | 1 |
| Matucci-Cerinic, M | 1 |
| Iannone, F | 1 |
| Carossino, A | 1 |
| Pignone, A | 1 |
| Leoncini, G | 1 |
| Generini, S | 1 |
| Lapadula, G | 1 |
| Cagnoni, M | 1 |
| Ohtsuka, T | 1 |
| Koibuchi, N | 1 |
| Sakai, H | 1 |
| Yamakage, A | 1 |
| Yamazaki, S | 1 |
| Alarcón-Segovia, D | 1 |
| Fishbein, E | 1 |
| García-Ortigoza, E | 1 |
| Estrada-Parra, S | 1 |
| Sherer, GK | 1 |
| Krieg, T | 1 |
| Hörlein, D | 1 |
| Wiestner, M | 1 |
| Müller, PK | 1 |
| Fleischmajer, R | 1 |
| Perlish, JS | 1 |
| Hirt, A | 1 |
| Wagner, HP | 1 |
| Majewski, S | 1 |
| Błaszczyk, M | 1 |
| Jabłonska, S | 1 |
| Rudnicka, L | 1 |
| Waşik, M | 1 |
| Skiendzielewska, A | 1 |
| Makieła, B | 1 |
| Holt, CM | 1 |
| Moult, J | 1 |
| Lindsey, N | 1 |
| Hughes, P | 1 |
| Greaves, M | 1 |
| Rowell, NR | 1 |
| Abakumova, OIu | 1 |
| Kutsenko, NG | 1 |
| Panasiuk, AF | 1 |
| Tamura, T | 1 |
| Ishikawa, H | 1 |
| Winkelstein, A | 1 |
| Rodnan, GP | 1 |
| Heilman, JD | 1 |
| Currie, S | 2 |
| Saunders, M | 2 |
| Knowles, M | 2 |
| Brown, AE | 1 |
| Hedberg, H | 1 |
| Källén, B | 1 |
| Löw, B | 1 |
| Nilsson, O | 1 |
23 other studies available for thymidine and Scleroderma, Systemic
| Article | Year |
|---|---|
Endothelial cell renewal in skin of patients with progressive systemic sclerosis (PSS): an in vitro autoradiographic study.
Topics: Adult; Aged; Autoradiography; Biopsy; Endothelium; Female; Forearm; Humans; In Vitro Techniques; Mal | 1982 |
Endothelial injury in scleroderma. A protease mechanism.
Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride | 1983 |
Failure of sera from patients with scleroderma to exhibit cytotoxicity towards human umbilical vein endothelial cells.
Topics: Adenosine Triphosphate; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytotoxicity, | 1984 |
Cytotoxicity of sera from patients with scleroderma. Effects on human endothelial cells and fibroblasts in culture.
Topics: Cells, Cultured; Endothelium; Fibroblasts; Humans; Scleroderma, Systemic; Thymidine | 1983 |
Increased mitogenic activity of scleroderma serum: inhibitory effect of human recombinant interferon-gamma.
Topics: Adult; beta-Thromboglobulin; Cells, Cultured; CREST Syndrome; Dose-Response Relationship, Drug; Fema | 1994 |
Impaired growth response to endothelin-1 in scleroderma fibroblasts.
Topics: Biopsy; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Endothelins; Endothelium, | 1995 |
Scleroderma fibroblast phenotype is modulated by endothelial cell co-culture.
Topics: Adult; Cell Count; Cell Division; Cell Transformation, Viral; Cells, Cultured; Coculture Techniques; | 1996 |
Discrepant expression of neprilysin on fibroblasts in diffuse systemic sclerosis.
Topics: Cell Division; Cell Membrane; Cells, Cultured; Fibroblasts; Flow Cytometry; Humans; Intracellular Fl | 1999 |
Simultaneous analysis of [3H]-thymidine uptake and alpha 1(I) procollagen mRNA expression in systemic sclerosis skin fibroblasts--an in situ hybridization study.
Topics: Aged; Autoradiography; Cells, Cultured; DNA; Humans; In Situ Hybridization; Middle Aged; Procollagen | 2000 |
Uracil-specific anti-R.N.A. antibodies in scleroderma.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antibodies; Cattle; Cross Reactions; Cytidine; Cytosine | 1975 |
Endothelial injury in scleroderma.
Topics: Adult; Cells, Cultured; Endothelium; Fibroblasts; Humans; Male; Muscle, Smooth; Raynaud Disease; Rhe | 1979 |
Aminoterminal extension peptides from type I procollagen normalize excessive collagen synthesis of scleroderma fibroblasts.
Topics: Collagen; Culture Techniques; Fibroblasts; Humans; Peptide Termination Factors; Procollagen; Sclerod | 1978 |
[3H]Thymidine labeling of dermal endothelial cells in scleroderma.
Topics: Adult; Autoradiography; Capillaries; Endothelium; Female; Humans; Male; Middle Aged; Scleroderma, Lo | 1977 |
Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Fem | 1975 |
Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action.
Topics: Cold Temperature; Collagen; Endothelins; Endothelium, Vascular; Fibroblasts; Humans; Proteins; Radio | 1991 |
Cytotoxic effects of sera from patients with systemic scleroderma: comparison of three different in vitro methods.
Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Chromium; Chromium Radioisotopes; Cytotoxicity Tests, I | 1990 |
Prostacyclin production by human umbilical vein endothelium in response to serum from patients with systemic sclerosis.
Topics: Adult; Aged; Cell Division; Endothelium, Vascular; Epoprostenol; Female; Humans; Male; Middle Aged; | 1989 |
[The regulation of DNA synthesis by fibronectin and its proteolytic products in the skin fibroblasts of healthy donors and patients with systemic scleroderma and rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Fibronec | 1989 |
Clinical significance of lymphocyte responsiveness to scleroderma-inducing glycosaminoglycan-associated antigen in systemic scleroderma.
Topics: Adolescent; Adult; Aged; DNA Replication; Female; Humans; Lymphocyte Activation; Lymphocytes; Male; | 1985 |
Cellular immunity in progressive systemic sclerosis (scleroderma).
Topics: Antigens; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lectins; Lymphocyte Activation; Lym | 1972 |
Immunological aspects of polymyositis. The in vitro activity of lymphocytes on incubation with muscle antigen and with muscle cultures.
Topics: Adolescent; Adult; Aged; Animals; Antigens; Antilymphocyte Serum; Child, Preschool; Culture Techniqu | 1971 |
Immunological aspects of systemic sclerosis in vitro activity of lymphocytes from patients with the disorder.
Topics: Adult; Animals; Antigens; Biopsy; Collagen; Culture Techniques; Cytotoxicity Tests, Immunologic; Der | 1971 |
Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides.
Topics: Arthritis; Arthritis, Rheumatoid; Culture Techniques; Humans; Leukocytes; Lymphocyte Activation; Mit | 1971 |