Page last updated: 2024-11-06

thymidine and Sarcoma

thymidine has been researched along with Sarcoma in 43 studies

Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

Research Excerpts

ExcerptRelevanceReference
"An in vitro double-labeling technique for determination of kinetic growth parameters was tested; 13 renal sarcomas of rats were incubated after excision under standardized conditions with 14C- and 3H-thymidine successively."7.66Determination of growth kinetics in a renal sarcoma of the rat by double labeling with 14C- and 3H-thymidine. ( Georgii, A; Kienzle, S; Lang, W, 1983)
"We present data from a pilot study in 10 soft-tissue sarcoma patients imaged with (11)C-thymidine for cellular proliferation, (18)F-fluoromisonidazole (FMISO) for tissue hypoxia, and (11)C-verapamil for P-glycoprotein activity, in comparison with (15)O-water for blood flow and (11)C-CO(2) for metabolite analysis and (18)F-FDG clinical scans."3.77Multiagent PET for risk characterization in sarcoma. ( Conrad, EU; Eary, JF; Krohn, KA; Link, JM; Mankoff, DA; Muzi, M; White, JK, 2011)
"Twenty patients who received high-dose methotrexate for osteosarcoma (n = 11), lymphoid cancers (n = 8), and gastric cancer (n = 1) developed nephrotoxicity (median serum creatinine, 3."3.69Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction. ( Adamson, PC; Balis, FM; Montello, MJ; Murphy, RF; O'Brien, M; Sorensen, JM; Widemann, BC, 1997)
"An in vitro double-labeling technique for determination of kinetic growth parameters was tested; 13 renal sarcomas of rats were incubated after excision under standardized conditions with 14C- and 3H-thymidine successively."3.66Determination of growth kinetics in a renal sarcoma of the rat by double labeling with 14C- and 3H-thymidine. ( Georgii, A; Kienzle, S; Lang, W, 1983)
"Fourteen of 20 lung cancer patients responded to lung cancer antigen, whereas only 11 of 41 patients with other tumors and 3 of 19 normal subjects reacted."1.26A rapid assay for stimulation of human lymphocytes by tumor-associated antigens. ( Grimm, EA; Morton, DL; Roth, JA, 1976)
"Serum from cancer patients impaired the response of normal lymphocytes."1.25The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. ( Kumar, S; Taylor, G, 1973)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199036 (83.72)18.7374
1990's4 (9.30)18.2507
2000's1 (2.33)29.6817
2010's2 (4.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duan, X1
Liu, T1
Zhang, Y1
Zhang, J1
Eary, JF2
Link, JM3
Muzi, M1
Conrad, EU1
Mankoff, DA2
White, JK1
Krohn, KA3
MARAINI, G1
FRANGUELLI, R1
OETTGEN, HF1
CLIFFORD, P1
CANDLER, P1
MCKHANN, CF2
NAORA, H2
TOBE, T1
KATO, T1
HIRAI, E1
YATOMI, K1
DIMARCO, A1
SILVESTRINI, R1
DASDIA, T1
DIMARCO, S1
SATO, M1
CERECEDO, LR1
SMITH, MJ1
VICENTE, J1
KURITA, Y1
MORIWAKI, K1
YOSIDA, TH1
Mohindra, A1
Bolderson, E1
Stone, J1
Wells, M1
Helleday, T1
Meuth, M1
Ming, SC1
Klein, E1
Klein, G1
Severin, E1
Ohnemus, B1
Lang, W1
Kienzle, S1
Georgii, A1
Shields, AF2
Mankoff, D1
Graham, MM2
Zheng, M2
Kozawa, SM2
Widemann, BC1
Balis, FM1
Murphy, RF1
Sorensen, JM1
Montello, MJ1
O'Brien, M1
Adamson, PC1
Lewellen, B1
Lewellen, TK1
Grierson, JR1
Parks, WP1
Ransom, JC1
Young, HA1
Scolnick, EM1
Chavaudra, N2
Malaise, EP2
Roth, JA1
Grimm, EA1
Morton, DL1
Fuska, J1
Proksa, B1
Fusková, A1
Cook, JA1
Glass, J1
Lebovics, R1
Bobo, H1
Pass, H1
DeLaney, TF1
Oldfield, EH1
Mitchell, JB1
Glatstein, E1
Goffman, TE1
Jagarlamoody, SM1
Kakefuda, T1
Dingman, CW1
Bak, TM1
Hatanaka, M1
Kitano, Y1
Takahashi, T1
Takeno, Y1
Takaki, R1
Kajiyama, T1
Takii, M1
Stinner, G1
Rose, A1
Steenbeck, L1
Waghe, M1
Kumar, S2
Steward, JK1
Tubiana, M1
Mavligit, GM1
Ambus, U1
Gutterman, JU1
Hersh, EM1
McBride, CM1
Müller, D1
Reichert, E1
Lang, HD1
Orywall, D1
Badger, AM1
Cooperband, SR1
Green, JA1
Catalona, WJ2
Sample, WF2
Chretien, PB2
Crowder, WL1
Gertner, HR1
Post, J1
Sklarew, RJ1
Hoffman, J1
Taylor, G1
Allin, EP1
Montagnier, L1
Citoler, P1
Drechsler, HJ1
Thomas, C1
Grossi-Paoletti, E1
Paoletti, P1
Pezzotta, S1
Schiffer, D1
Fabiani, A1
Wright, DH1
Peel, S1
Cooper, EH1
Hughes, DT1
Iversen, U1
Iversen, OH1
Hennings, H1
Bjerknes, R1
Merkulov, MF1
Shelaputina, ZF1
Iavorskaia, NP1
Leskova, SG1
Fettig, O1
Oehlert, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal Dysfunction[NCT00001298]Phase 110 participants Interventional1992-03-31Completed
A Pilot Study of 18F FLT PET/CT in Evaluating Early Response to Anti-Proliferative Therapies in Non Small Cell Lung Cancer and Thymic Tumors[NCT01610544]Phase 20 participants (Actual)Interventional2012-05-10Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thymidine and Sarcoma

ArticleYear
Evidence for immune reactivity against neoplasms.
    Transplantation reviews, 1971, Volume: 7

    Topics: Animals; Antibodies; Antibody Formation; Antigens; Antigens, Neoplasm; Antigens, Viral; Binding Site

1971

Other Studies

42 other studies available for thymidine and Sarcoma

ArticleYear
Synthesis and Biological Evaluation of Novel (99m)Tc(CO)₃-Labeled Thymidine Analogs as Potential Probes for Tumor Proliferation Imaging.
    Molecules (Basel, Switzerland), 2016, Apr-19, Volume: 21, Issue:4

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Drug Stability; Mice; Neoplasm Trans

2016
Multiagent PET for risk characterization in sarcoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:4

    Topics: Carbon Dioxide; Feasibility Studies; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assi

2011
[RADIOAUTOGRAPHICAL STUDY OF THE PROLIFERATIVE ACTIVITY OF THE VARIOUS TYPES OF CELLULAR ELEMENTS IN A MELANOTIC SARCOMA OF THE IRIS AND CILIARY BODY].
    Bollettino d'oculistica, 1963, Volume: 42

    Topics: Autoradiography; Ciliary Body; DNA; DNA, Neoplasm; Eye Neoplasms; Humans; Iris; Melanoma; Metabolism

1963
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
    Cancer chemotherapy reports, 1963, Volume: 32

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona

1963
DESTRUCTION OF IMMUNE LYMPHOID CELLS IN TRANSPLANTATION IMMUNITY.
    Journal of immunology (Baltimore, Md. : 1950), 1963, Volume: 91

    Topics: Animals; Autoradiography; Immunity; Lymphocytes; Lymphoid Tissue; Mice; Research; Sarcoma; Sarcoma,

1963
SOME OBSERVATIONS ON THE REGULATORY CONTROL OF THE MULTIPLICATION OF MOUSE HEPATIC CELLS.
    Experimental cell research, 1964, Volume: 33

    Topics: Autoradiography; Cell Division; DNA; Hepatocytes; Liver; Mice; Research; Sarcoma; Sarcoma, Experimen

1964
[ON THE CELL CYCLE OF YOSHIDA ASCITES TUMOR. AN AUTORADIOGRAPHIC STUDY].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1964, Volume: 24

    Topics: Animals; Ascites; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Biology; Cell Cycle; Cell Division

1964
AUTORADIOGRAPHIC STUDY OF THE DISTRIBUTION OF DNA IN NORMAL NEOPLASTIC AND URETHANE-TREATED CELLS.
    Experimental cell research, 1964, Volume: 35

    Topics: Autoradiography; DNA; DNA, Neoplasm; Neoplasms; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Expe

1964
THE INFLUENCE OF THE INHIBITION OF GLYCOLYSIS ON GLYCOGENESIS AND DNA SYNTHESIS IN ASCITES TUMOR CELLS.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1964, Volume: 11

    Topics: Animals; Ascites; Autoradiography; Carcinoma, Ehrlich Tumor; DNA; DNA Replication; DNA, Neoplasm; Gl

1964
TUMOR-HOST RELATIONSHIPS STUDIED IN VITRO: EXPERIMENTS WITH TISSUE SLICES.
    Archives of biochemistry and biophysics, 1964, Volume: 108

    Topics: Adenine; Carcinoma 256, Walker; DNA; In Vitro Techniques; Kidney; Liver; Lung; Lymphoma, Non-Hodgkin

1964
[AUTORADIOGRAPHIC ANALYSIS OF THE MITOTIC CYCLE IN YOSHIDA SARCOMA CELLS].
    Gan, 1964, Volume: 55

    Topics: Animals; Autoradiography; Biometry; Cell Division; Mitosis; Rats; Research; Sarcoma; Sarcoma, Yoshid

1964
A tumour-derived mutant allele of XRCC2 preferentially suppresses homologous recombination at DNA replication forks.
    Human molecular genetics, 2004, Jan-15, Volume: 13, Issue:2

    Topics: Base Pair Mismatch; Camptothecin; DNA; DNA Repair; DNA Replication; DNA-Binding Proteins; Female; Ge

2004
Inhibition of DNA synthesis of target cells in vitro by sensitized lymphocytes.
    Nature, 1967, Sep-23, Volume: 215, Issue:5108

    Topics: Animals; Autoradiography; Carbon Isotopes; Culture Techniques; DNA; Embryo, Mammalian; Lymphocytes;

1967
UV dose-dependent increase in the Hoechst fluorescence intensity of both normal and BrdU-DNA.
    Histochemistry, 1982, Volume: 74, Issue:2

    Topics: Animals; Benzimidazoles; Bisbenzimidazole; Bromodeoxyuridine; DNA; DNA, Neoplasm; Dose-Response Rela

1982
Determination of growth kinetics in a renal sarcoma of the rat by double labeling with 14C- and 3H-thymidine.
    Journal of cancer research and clinical oncology, 1983, Volume: 105, Issue:1

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Division; Female; Kidney Neoplasms; Methods; Mi

1983
Analysis of 2-carbon-11-thymidine blood metabolites in PET imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:2

    Topics: Carbon Dioxide; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Humans; Lung Neoplasms;

1996
Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:5

    Topics: Adolescent; Adult; Antidotes; Antimetabolites, Antineoplastic; Carboxypeptidases; Child; Child, Pres

1997
Carbon-11-thymidine and FDG to measure therapy response.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carbon Radioisotopes; Carcinoma, Small Cell; Fluorin

1998
Mammary tumor virus induction by glucocorticoids. Characterization of specific transcriptional regulation.
    The Journal of biological chemistry, 1975, May-10, Volume: 250, Issue:9

    Topics: Adenocarcinoma; Animals; Cell Line; Dexamethasone; DNA, Viral; Dose-Response Relationship, Drug; Leu

1975
In vitro incorporation of [3H]TdR in human and murine solid tumours. Influence of 5-fluorouracil and/or hyperbaric oxygen on spatial distribution of labelling.
    Cell and tissue kinetics, 1979, Volume: 12, Issue:6

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Fluorouracil; Humans; Mice; Neoplasms; Neoplasms

1979
A rapid assay for stimulation of human lymphocytes by tumor-associated antigens.
    Cancer research, 1976, Volume: 36, Issue:9 pt.1

    Topics: Antigens, Neoplasm; Carcinoma; Female; Hemagglutination Tests; Hemocyanins; Humans; Leucine; Lung; L

1976
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
    Neoplasma, 1975, Volume: 22, Issue:3

    Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leu

1975
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
    Cancer research, 1992, Feb-01, Volume: 52, Issue:3

    Topics: Animals; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Flow Cytometry; Glioma; Head and Neck

1992
Reverse transcription of the viral genome associated with the plasma membrane after infection with RNA tumor viruses.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Animals; Autoradiography; Cell Fractionation; Cell Membrane; Cells, Cultured; Centrifugation, Densit

1974
Screening of carcinostatic agents in organ culture.
    Gan, 1968, Volume: 59, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma; Cerebellar Neoplasms; Chickens; Culture Techniques;

1968
[Studies on the function of granulopoiesis after cytostatic therapy and bone marrow transfusions].
    Folia haematologica (Leipzig, Germany : 1928), 1969, Volume: 91, Issue:2

    Topics: Agranulocytosis; Antineoplastic Agents; Bone Marrow Transplantation; Carcinoma; Cyclophosphamide; He

1969
Tissue culture studies of children's tumours.
    The Journal of pathology, 1973, Volume: 111, Issue:2

    Topics: Autoradiography; Child; Culture Media; Culture Techniques; Cytotoxicity Tests, Immunologic; Freezing

1973
The relationship between growth rate, labelling index and histological type of human solid tumours.
    European journal of cancer, 1973, Volume: 9, Issue:4

    Topics: Adenocarcinoma; Autoradiography; Carcinoma, Squamous Cell; Cell Division; Hemangiosarcoma; Humans; N

1973
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity.
    Nature: New biology, 1973, Jun-06, Volume: 243, Issue:127

    Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans;

1973
[Cell cycle and ineffective cell renewal in disturbed granulo- and erythropoiesis. Combined pulse-cytophotometry, feulgen-photometry, 3H-thymidine- autoradiographic and cytogenetic investigations (author's transl)].
    Klinische Wochenschrift, 1974, Apr-15, Volume: 52, Issue:8

    Topics: Adult; Aged; Anemia, Aplastic; Autoradiography; Chromosome Mapping; DNA; Erythropoiesis; Female; Gra

1974
Effect of polyriboinosinic-polyribocytidylic acid on the metabolism and viability of cells in vitro.
    Journal of the National Cancer Institute, 1972, Volume: 49, Issue:3

    Topics: Amnion; Animals; Cell Line; Cells, Cultured; Conjunctiva; DNA; DNA, Neoplasm; HeLa Cells; Humans; L

1972
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage.
    Cancer, 1973, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq

1973
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients.
    Surgery, gynecology & obstetrics, 1973, Volume: 136, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H

1973
Cell proliferation patterns in an autogenous rat sarcoma.
    Journal of the National Cancer Institute, 1973, Volume: 50, Issue:2

    Topics: Analysis of Variance; Animals; Autoradiography; Carbon Isotopes; Cell Division; Connective Tissue Ce

1973
The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients.
    Journal of clinical pathology, 1973, Volume: 26, Issue:7

    Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lectins; Leukemia; Lymph

1973
Protein synthesis and changes in DNA-sarkosyl complexes during the S-phase of synchronised BHK21 cells.
    Biochimie, 1973, Volume: 55, Issue:3

    Topics: Animals; Asparagine; Carbon Radioisotopes; Cell Division; Cell Line; Cell Nucleus; Cell Transformati

1973
[Blood brain barrier for thymidine in experimentally produced tumors of the central nervous system of the rat].
    Virchows Archiv. B, Cell pathology, 1971, Volume: 7, Issue:2

    Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; DNA, Neoplasm; Glioma; Neoplasms, Ex

1971
Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics.
    Journal of neurosurgery, 1972, Volume: 37, Issue:5

    Topics: Animals; Brain; Brain Neoplasms; Desmosterol; DNA; DNA, Neoplasm; Ependymoma; Female; Glioma; Neuril

1972
Transmissible venereal sarcoma of dogs. A histochemical and chromosomal analysis of tumours in Uganda.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1970, Volume: 15, Issue:2

    Topics: Animals; Chromosome Aberrations; DNA, Neoplasm; Dog Diseases; Dogs; Female; Histocytochemistry; Kary

1970
Diurnal variation in susceptibility of mouse skin to the tumorigenic action of methylcholanthrene.
    Journal of the National Cancer Institute, 1970, Volume: 45, Issue:2

    Topics: Animals; Carcinoma; Circadian Rhythm; DNA; Female; Male; Methylcholanthrene; Mice; Mitosis; Papillom

1970
[Incorporation of H3-thymidine into the DNA of cells of surviving slices of transplantable tumors, sensitive and resistant to sarcolysine].
    Farmakologiia i toksikologiia, 1970, Volume: 33, Issue:6

    Topics: Animals; Autoradiography; Body Weight; Depression, Chemical; DNA, Neoplasm; In Vitro Techniques; Mel

1970
[Radioautographic metabolic studies with tritium-labeled substances in tumor tissues of the human uterus].
    Nuclear-Medizin, 1965, Volume: 2

    Topics: Adenocarcinoma; Autoradiography; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Humans; Neoplasm M

1965