thymidine has been researched along with Renal Insufficiency in 7 studies
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The antiviral efficacy and safety of telbivudine (LdT) have been shown in patients with CHB infection, and LdT is approved as a class B drug for pregnancy." | 8.95 | Telbivudine therapy for gravidas with chronic hepatitis B infection and patients at risk of renal impairment. ( Chen, T; Liu, J; Zhao, Y, 2017) |
| "Previous studies have demonstrated that the treatment of chronic hepatitis B (CHB) infection with adefovir (ADV) can impair renal function." | 7.80 | Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy. ( Kim, HY; Kim, YJ; Lee, HJ; Lee, HS; Lee, JH; Lee, M; Oh, S; Yeum, TS; Yoon, JH; Yu, SJ, 2014) |
| " The antiviral efficacy and safety of telbivudine (LdT) have been shown in patients with CHB infection, and LdT is approved as a class B drug for pregnancy." | 4.95 | Telbivudine therapy for gravidas with chronic hepatitis B infection and patients at risk of renal impairment. ( Chen, T; Liu, J; Zhao, Y, 2017) |
| "Previous studies have demonstrated that the treatment of chronic hepatitis B (CHB) infection with adefovir (ADV) can impair renal function." | 3.80 | Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy. ( Kim, HY; Kim, YJ; Lee, HJ; Lee, HS; Lee, JH; Lee, M; Oh, S; Yeum, TS; Yoon, JH; Yu, SJ, 2014) |
| "Intoxication due to insufficient renal clearance developed in 2 patients, a 54-year-old man and a 61-year-old woman, who were under treatment with methotrexate (MTX) for a primary cerebral lymphoma and a recurrence of large-cell B-cell-non-Hodgkin lymphoma, respectively." | 3.74 | [Management recommendations in patients with methotrexate intoxication]. ( Beijnen, JH; Schellens, JH, 2007) |
| "New insights into the treatment of chronic hepatitis B with relevance for clinical practice have been adopted in these concise, revised guidelines." | 1.38 | The 2012 revised Dutch national guidelines for the treatment of chronic hepatitis B virus infection. ( Baak, BC; Bakker, CM; Beuers, UH; Brouwer, JT; Buster, EH; Drenth, JP; Honkoop, P; Janssen, HL; Kerbert-Dreteler, MJ; Koek, GH; Tan, AC; van der Spek, BW; van Erpecum, KJ; van Hoek, B; van Nieuwkerk, KM; van Soest, H; Vrolijk, JM, 2012) |
| "Thymidine uptake was progressively greater with more advanced renal failure and was linearly correlated with (creatinine)-1." | 1.29 | Mesangial cell proliferation is directly enhanced by sera from patients with renal insufficiency. ( Abramovici, M; Mattana, J; Singhal, PC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Hunt, M | 1 |
| Phillips, R | 1 |
| Hardy, Y | 1 |
| Owusu, DO | 1 |
| Mitchelmore, R | 1 |
| Durrani, M | 1 |
| Payne, BAI | 1 |
| Chadwick, DR | 1 |
| Liu, J | 1 |
| Chen, T | 1 |
| Zhao, Y | 1 |
| Lee, M | 1 |
| Oh, S | 1 |
| Lee, HJ | 1 |
| Yeum, TS | 1 |
| Lee, JH | 1 |
| Yu, SJ | 1 |
| Kim, HY | 1 |
| Yoon, JH | 1 |
| Lee, HS | 1 |
| Kim, YJ | 1 |
| Buster, EH | 1 |
| Baak, BC | 1 |
| Bakker, CM | 1 |
| Beuers, UH | 1 |
| Brouwer, JT | 1 |
| Drenth, JP | 1 |
| van Erpecum, KJ | 1 |
| van Hoek, B | 1 |
| Honkoop, P | 1 |
| Kerbert-Dreteler, MJ | 1 |
| Koek, GH | 1 |
| van Nieuwkerk, KM | 1 |
| van Soest, H | 1 |
| van der Spek, BW | 1 |
| Tan, AC | 1 |
| Vrolijk, JM | 1 |
| Janssen, HL | 1 |
| Schellens, JH | 1 |
| Beijnen, JH | 1 |
| Mattana, J | 1 |
| Abramovici, M | 1 |
| Singhal, PC | 1 |
| Frankel, AE | 1 |
| Powell, BL | 1 |
| Hall, PD | 1 |
| Case, LD | 1 |
| Kreitman, RJ | 1 |
1 review available for thymidine and Renal Insufficiency
| Article | Year |
|---|---|
Telbivudine therapy for gravidas with chronic hepatitis B infection and patients at risk of renal impairment.
Topics: Animals; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Pregnancy; Pregnancy Complications, | 2017 |
1 trial available for thymidine and Renal Insufficiency
| Article | Year |
|---|---|
Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotran | 2002 |
5 other studies available for thymidine and Renal Insufficiency
| Article | Year |
|---|---|
Renal mitochondrial toxicity: effects of thymidine analogues and tenofovir disoproxil fumarate in African people with HIV.
Topics: Anti-HIV Agents; Ghana; HIV Infections; Humans; Mitochondria; Renal Insufficiency; Tenofovir; Thymid | 2022 |
Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Glomerular Fi | 2014 |
The 2012 revised Dutch national guidelines for the treatment of chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Drug Approval; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chro | 2012 |
[Management recommendations in patients with methotrexate intoxication].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Humans; Kidney; Leucovorin; Lymphoma; Lymp | 2007 |
Mesangial cell proliferation is directly enhanced by sera from patients with renal insufficiency.
Topics: Animals; Cell Division; Cells, Cultured; Creatinine; Dose-Response Relationship, Drug; Glomerular Me | 1993 |