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thymidine and Pulmonary Fibrosis

thymidine has been researched along with Pulmonary Fibrosis in 17 studies

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days."7.66Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979)
"The angiotensin converting enzyme (ACE) inhibitor captopril, a free-thiol compound used widely as an antihypertensive agent, also inhibits radiation-induced pulmonary fibrosis in rats (Ward et al."3.69Captopril inhibits proliferation of human lung fibroblasts in culture: a potential antifibrotic mechanism. ( Molteni, A; Nguyen, L; Ts'ao, CH; Ward, WF, 1994)
"An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days."3.66Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979)
"One form of idiopathic pulmonary fibrosis (IPF), usual intersitial pneumonia (UIP) is characterized pathologically by patchily distributed fibrotic areas in apparently normal parenchyma."1.28[Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with the usual interstitial pneumonia form of idiopathic pulmonary fibrosis]. ( Mio, T, 1991)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's7 (41.18)18.2507
2000's2 (11.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walters, DM1
Antao-Menezes, A1
Ingram, JL1
Rice, AB1
Nyska, A1
Tani, Y1
Kleeberger, SR1
Bonner, JC1
Mornex, JF1
Cordier, G1
Revillard, JP1
Adamson, IY3
Bakowska, J1
Bowden, DH1
Nguyen, L1
Ward, WF1
Ts'ao, CH1
Molteni, A1
Yano, H1
Yoshizawa, Y1
Satoh, T1
Ohtsuka, M1
Murayama, J1
Homma, T1
Hasegawa, S1
Melloni, B1
Lesur, O1
Cantin, A1
Bégin, R1
Prieditis, H1
Hedgecock, C1
Vincent, R1
Griffin, M1
Smith, LL2
Wynne, J1
Haschek, WM1
Witschi, H2
Rose, MS1
Mio, T2
Nagai, S1
Kitaichi, M1
Kawatani, A1
Izumi, T1
Kanekal, S1
Fraiser, L1
Kehrer, JP1
Tryka, AF1
Lindenschmidt, RC1
Bach, MC1
Helbert, M1
Stoneham, C1
Mitchell, D1
Pinching, AJ1

Reviews

1 review available for thymidine and Pulmonary Fibrosis

ArticleYear
Drug-induced pulmonary fibrosis.
    Environmental health perspectives, 1984, Volume: 55

    Topics: Animals; Bleomycin; Humans; Lung; Mitosis; Pulmonary Fibrosis; Species Specificity; Thymidine; Wound

1984

Other Studies

16 other studies available for thymidine and Pulmonary Fibrosis

ArticleYear
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
    The American journal of pathology, 2005, Volume: 167, Issue:5

    Topics: Animals; Bleomycin; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Disease Models

2005
[Markers of lymphocyte activation in interstitial pulmonary disease].
    Revue francaise des maladies respiratoires, 1983, Volume: 11, Issue:4

    Topics: DNA; Flow Cytometry; Humans; Lymphocyte Activation; Lymphocyte Cooperation; Lymphocytes; Pulmonary A

1983
Mesothelial cell proliferation: a nonspecific response to lung injury associated with fibrosis.
    American journal of respiratory cell and molecular biology, 1994, Volume: 10, Issue:3

    Topics: Animals; Asbestos, Crocidolite; Autoradiography; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Divis

1994
Captopril inhibits proliferation of human lung fibroblasts in culture: a potential antifibrotic mechanism.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1994, Volume: 205, Issue:1

    Topics: Angiotensin II; Animals; Captopril; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug;

1994
[Pathogenesis of development of lung cancer in idiopathic interstitial pneumonia--growth factors in bronchoalveolar lavage fluid].
    Nihon Kyobu Shikkan Gakkai zasshi, 1993, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Animals; Bronchoalveolar Lavage Fluid; Growth Substances; Humans; Lung Neop

1993
Silica-exposed macrophages release a growth-promoting activity for type II pneumocytes.
    Journal of leukocyte biology, 1993, Volume: 53, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Count; Cell Survival; Cells, Cultured; Culture Media, Co

1993
Zinc is the toxic factor in the lung response to an atmospheric particulate sample.
    Toxicology and applied pharmacology, 2000, Jul-15, Volume: 166, Issue:2

    Topics: Air Pollutants; Animals; Autoradiography; Bronchoalveolar Lavage Fluid; Cell Count; Cell Division; D

2000
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
    British journal of experimental pathology, 1979, Volume: 60, Issue:6

    Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; L

1979
Pulmonary fibrosis--a possible mechanism.
    Toxicology and applied pharmacology, 1979, Volume: 51, Issue:3

    Topics: Animals; Butylated Hydroxytoluene; DNA; Hydroxyproline; Lung; Male; Mice; Mice, Inbred BALB C; Organ

1979
A comparison of the effects of paraquat and diquat on the water content of rat lung and the incorporation of thymidine into lung DNA.
    Toxicology, 1977, Volume: 8, Issue:2

    Topics: Animals; Diquat; DNA; Lethal Dose 50; Lung; Lung Diseases; Male; Paraquat; Pulmonary Edema; Pulmonar

1977
Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP).
    Chest, 1992, Volume: 102, Issue:3

    Topics: Cell Division; Cell Line; Dinoprostone; Female; Fibroblasts; Humans; In Vitro Techniques; Lung; Male

1992
Pharmacokinetics, metabolic activation, and lung toxicity of cyclophosphamide in C57/B16 and ICR mice.
    Toxicology and applied pharmacology, 1992, Volume: 114, Issue:1

    Topics: Animals; Biotransformation; Cyclophosphamide; Disease Susceptibility; DNA; Hydroxyproline; Injection

1992
[Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with the usual interstitial pneumonia form of idiopathic pulmonary fibrosis].
    Nihon Kyobu Shikkan Gakkai zasshi, 1991, Volume: 29, Issue:9

    Topics: Aged; Cell Division; Cell Line; Dinoprostone; Female; Fibroblasts; Humans; Lung; Male; Middle Aged;

1991
Progressive pulmonary fibrosis in rats: a biochemical, cell kinetic, and morphologic analysis.
    Experimental and molecular pathology, 1985, Volume: 43, Issue:3

    Topics: Animals; Bleomycin; Collagen; Hydroxyproline; Male; Oxygen; Pulmonary Alveoli; Pulmonary Fibrosis; R

1985
Zidovudine for lymphocytic interstitial pneumonia associated with AIDS.
    Lancet (London, England), 1987, Oct-03, Volume: 2, Issue:8562

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Humans; Male; Middle Aged; Pulmonary Fi

1987
Zidovudine for lymphocytic interstitial pneumonitis in AIDS.
    Lancet (London, England), 1987, Dec-05, Volume: 2, Issue:8571

    Topics: Acquired Immunodeficiency Syndrome; Humans; Male; Middle Aged; Pulmonary Fibrosis; Thymidine; Zidovu

1987