Page last updated: 2024-11-06

thymidine and Prostatic Neoplasms

thymidine has been researched along with Prostatic Neoplasms in 113 studies

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"After transplantation of rat prostate adenocarcinoma cells, dynamic PET measurements with fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose (18FDG) were performed in 15 animals before and 1 day after therapy with 90 mg/kg of body weight (n = 8) and 180 mg/kg of body weight (n = 7) gemcitabine."7.69PET 2-fluoro-2-deoxyglucose uptake in rat prostate adenocarcinoma during chemotherapy with gemcitabine. ( Altmann, A; Bellemann, ME; Blatter, J; Brix, G; Doll, J; Gerlach, L; Haberkorn, U; Morr, I; Oberdorfer, F; van Kaick, G, 1997)
"The thymidine labeling index (TLI) was measured in vitro in the epithelium and stroma of benign prostate glands and seminal vesicles and in the epithelium of prostatic adenocarcinomas."7.66Proliferative activity of benign human prostate, prostatic adenocarcinoma and seminal vesicle evaluated by thymidine labeling. ( Martin, SA; Meyer, JS; Sufrin, G, 1982)
"After transplantation of rat prostate adenocarcinoma cells, dynamic PET measurements with fluorine-18-labeled 2-fluoro-2-deoxy-D-glucose (18FDG) were performed in 15 animals before and 1 day after therapy with 90 mg/kg of body weight (n = 8) and 180 mg/kg of body weight (n = 7) gemcitabine."3.69PET 2-fluoro-2-deoxyglucose uptake in rat prostate adenocarcinoma during chemotherapy with gemcitabine. ( Altmann, A; Bellemann, ME; Blatter, J; Brix, G; Doll, J; Gerlach, L; Haberkorn, U; Morr, I; Oberdorfer, F; van Kaick, G, 1997)
"The effects of exogenously added urokinase type plasminogen activator, tissue type plasminogen activator, plasmin and thrombin on the proliferation of primary cultures of cells derived from prostatic hyperplasia or prostatic carcinomas were investigated by measuring the incorporation of 3H-thymidine into the cultures."3.67Effect of urokinase on the proliferation of primary cultures of human prostatic cells. ( Binder, BR; Christ, G; Heger, ME; Hienert, G; Kirchheimer, JC; Pflüger, H; Wojta, J, 1987)
"The thymidine labeling index (TLI) was measured in vitro in the epithelium and stroma of benign prostate glands and seminal vesicles and in the epithelium of prostatic adenocarcinomas."3.66Proliferative activity of benign human prostate, prostatic adenocarcinoma and seminal vesicle evaluated by thymidine labeling. ( Martin, SA; Meyer, JS; Sufrin, G, 1982)
" Because the guanylate cyclase-cyclic GMP system is though to be involved in cell growth, DNA and RNA synthesis, and possible malignant transformation, we examined the effect of the aqueous extract containing GCI on an undifferentiated adenocarcinoma of the rat prostate and concanavalin-A-stimulated [3H]thymidine incorporation into cultured splenic lymphocytes, a process thought to be mediated by cyclic GMP."3.66Inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (Momordica charantia abbreviata). ( Bagwell, CB; Block, NL; Claflin, AJ; Fletcher, MA; Hudson, JL; Lehotay, DC; Levey, GS; Lo, TM; Vesely, DL, 1978)
"However, in the case of breast and prostate cancer sera, TK 210 ELISA had higher sensitivity (59% and 44%) compared to [3H]-dThd phosphorylation assay (47% and 25%) at a specificity of 98%."1.72Analytical and clinical characterization of an optimized dual monoclonal sandwich ELISA for the quantification of thymidine kinase 1 (TK1) protein in human blood samples. ( J, O; Jagarlamudi, KK; L, S; M, Z; P, V; S, E, 2022)
"The results in human prostate cancer cell lines demonstrate the presence of ATIP in both cell lines examined, and suggest that (i) the AT(2)-receptor through an interaction with ATIP mediates an anti-growth factor effect in both androgen-dependent and androgen-independent cell lines; (ii) ATIP expression decreases as the rate of cell growth and androgen-independence increase; and (iii) EGF may act on cell growth in part by reducing the content of ATIP present in the cells."1.36Expression and function of ATIP/MTUS1 in human prostate cancer cell lines. ( Catt, KJ; Chow, L; Frauman, AG; Krezel, MA; Louis, SN; Louis, WJ; Rezmann, L; Tikellis, C, 2010)
"BRCA2 protein depletion after cancer cell adhesion to COL1 or in small RNA interference assays triggers new DNA synthesis, a trophic effect that is abrogated by recombinant BRCA2 expression."1.33Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. ( Arbini, AA; Greco, M; Marra, E; Moro, L, 2005)
" Tocopherols and saponins extracted from argan tree and 2-methoxyestradiol exhibit a dose-response cytotoxic effect and an antiproliferative action on the tested cell lines."1.33Tocopherols and saponins derived from Argania spinosa exert, an antiproliferative effect on human prostate cancer. ( Adlouni, A; Bennani, H; Charrouf, Z; Drissi, A; Fiet, J; Giton, F, 2006)
"Prostate cancer is an androgen-dependent disease; metastatic prostate cancer is typically treated by androgen receptor (AR) blockade."1.33Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. ( Agoulnik, IU; Alvarado, M; Ayala, GE; Bingman, WE; Erdem, H; Frolov, A; Ittmann, MM; Nakka, M; Smith, CL; Vaid, A; Weigel, NL, 2006)
"Bone metastases from prostate cancer cause abnormal new bone formation, however, the factors involved and the pathways leading to the response are incompletely defined."1.32IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells. ( Bhattacharyya, RS; Stern, PH, 2003)
" We performed pharmacokinetic measurements with [(14)C]FMAU and PET studies with [(11)C]FMAU using rats bearing several different syngeneic tumors."1.32Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats. ( Alauddin, MM; Bading, JR; Bathija, P; Conti, PS; Fissekis, JD; Koda, RT; Koszalka, GW; Shahinian, AH; Vail, A, 2004)
" Therefore, we have investigated the effects of the orally bioavailable Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) on the radiosensitivity of human tumor cells in vitro and grown as tumor xenografts."1.32Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin. ( Brady, KJ; Bull, EE; Burgan, WE; Camphausen, K; Carter, DJ; Cerra, MA; Dote, H; Hollingshead, MG; Oswald, KA; Tofilon, PJ, 2004)
"Juvenile Batten disease is a neurodegenerative disease caused by accelerated apoptotic death of photoreceptors and neurons attributable to defects in the CLN3 gene."1.31The CLN3 gene is a novel molecular target for cancer drug discovery. ( Amalfitano, A; Boustany, RM; Chang, J; Guo, WX; Jansen, PJ; Persaud-Sawin, DA; Proia, AD; Rylova, SN, 2002)
"Melatonin did not suppress and even slightly enhanced the capacity of AR binding to the ARE in the PC3-AR as well as in LNCaP cells."1.31Differential regulation by melatonin of cell growth and androgen receptor binding to the androgen response element in prostate cancer cells. ( Lupowitz, Z; Rimler, A; Zisapel, N, 2002)
" [3H]Thymidine incorporation displayed a bell-shaped dose-response curve in both strains."1.30LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids. ( Esquenet, M; Heyns, W; Swinnen, JV; Verhoeven, G, 1997)
"Four human prostate cancer cell lines were studied."1.30Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells. ( Bahk, JY; Cho, GJ; Choi, WS; Hyun, JS; Kim, MO; Lee, BH; Lee, H, 1998)
"Suramin is an effective antitumor agent in hormone-refractory prostate cancer, but its mechanism(s) of action is not well understood."1.29Inhibition of fibroblast hyaluronic acid production by suramin. ( August, EM; Cysyk, RL; Duncan, KL; Malinowski, NM, 1993)
"Suramin is an anthelmintic drug that recently has been shown to have clinical efficacy in the treatment of patients with some advanced malignancies, including prostate carcinoma."1.29Effect of suramin on the mitogenic response of the human prostate carcinoma cell line PC-3. ( Ewing, MW; Gnarra, JR; Linehan, WM; Liu, SC; Meyers, CE; Walther, MM, 1993)
" After dosing with the D-compound, the highest levels of radioactivity were found in the liver, kidneys, thymus, thyroid gland, and central nervous system, including the brain."1.29Pharmacokinetics and whole-body distribution of the new chemotherapeutic agent beta-D-glucosylisophosphoramide mustard and its effects on the incorporation of [methyl-3H]-thymidine in various tissues of the rat. ( Bertram, B; Bollow, U; Hull, WE; Pohl, J; Port, R; Schaper, M; Stüben, J; Wiessler, M, 1996)
"We observed that these three prostate cancer cell lines, which differed in their dependence on androgens for growth in vitro and in their in vivo behavior in nude mice, could be distinguished as follows: (a) androgen-sensitive LNCaP cells, which do not metastasize in nude mice, did not produce measurable amounts of bFGF, expressed small but measurable amounts of FGF receptor mRNA, and did respond to exogeneous bFGF; (b) androgen-insensitive, moderately metastatic DU 145 cells did produce measurable amounts of biologically active bFGF, expressed large amounts of FGF receptor mRNA, and responded to exogeneous bFGF and the heparin-binding fractions from DU 145 cell extracts; (c) androgen-insensitive and highly metastatic PC3 cells also produced measurable amounts of bFGF but did not demonstrate a growth response to either the heparin-binding fractions from PC3 cell extracts or exogenous bFGF, even though large amounts of FGF receptor mRNA were expressed in PC 3 cells."1.28Basic fibroblast growth factor in human prostate cancer cells. ( Chang, CS; Chodak, GW; Li, AK; Nakamoto, T, 1992)
" Growth in monolayer was initially inhibited in a dose-response fashion in the two androgen-independent cell lines, PC3 and DU145 but not in the androgen-dependent LNCaP cells."1.28Differential effects of transforming growth factor beta on human prostate cancer cells in vitro. ( Flanders, K; Gelmann, E; Knabbe, C; Wilding, G; Zugmeier, G, 1989)
"3H-thymidine incorporation was greater with human serum, with up to 120 per cent increase observed."1.26The effect of human serum on 3H-thymidine incorporation in human prostate tumors in tissue culture. ( Boileau, M; Hodges, CV; Keenan, E; Kemp, E; Lawson, R, 1978)
"The sera from patients with prostatic cancer have been observed to posses an unidentified factor capable of inhibiting the migration of leukocytes and the proliferative response to the nonspecific mitogen, phytohemagglutinin."1.25Serum proteins in prostatic cancer. II. Effect on in vitro cell-mediated immunologic responsiveness. ( Ablin, RJ; Bruns, GR; Bush, IM; Guinan, PD; Sadoughi, N, 1975)

Research

Studies (113)

TimeframeStudies, this research(%)All Research%
pre-199037 (32.74)18.7374
1990's37 (32.74)18.2507
2000's34 (30.09)29.6817
2010's4 (3.54)24.3611
2020's1 (0.88)2.80

Authors

AuthorsStudies
Jagarlamudi, KK1
L, S1
M, Z1
J, O1
P, V1
S, E1
Dueregger, A1
Guggenberger, F1
Barthelmes, J1
Stecher, G1
Schuh, M1
Intelmann, D1
Abel, G1
Haunschild, J1
Klocker, H1
Ramoner, R1
Sampson, N1
Lombardi, AP1
Pisolato, R1
Vicente, CM1
Lazari, MF1
Lucas, TF1
Porto, CS1
Thomas, F1
Patel, S1
Holly, JM1
Persad, R1
Bahl, A1
Perks, CM1
Lin, L1
Sheng, J1
Momin, RK1
Du, Q1
Huang, Z1
Johnson, T1
Ouhtit, A1
Gaur, R1
Fernando, A1
Schwarzenberger, P2
Su, J1
Ismail, MF1
El-Sayyad, HI1
Karande, A1
Elmageed, ZA1
Rao, P1
Raj, M1
Katayama, H1
Murashima, T1
Saeki, Y1
Nishizawa, Y1
Louis, SN1
Chow, L1
Rezmann, L1
Krezel, MA1
Catt, KJ1
Tikellis, C1
Frauman, AG1
Louis, WJ1
Mémin, E1
Yehia, G1
Razavi, R1
Molina, CA1
Davila, M1
Frost, AR1
Grizzle, WE2
Chakrabarti, R1
Swamy, N2
Persons, KS1
Chen, TC3
Ray, R2
KATO, T1
ISHIBE, T1
HIRAYAMA, M1
FUKUSHIGE, M1
TAKENAKA, I1
KAZUTA, M2
Bhattacharyya, RS1
Stern, PH1
Sánchez, MG1
Sánchez, AM1
Ruiz-Llorente, L1
Díaz-Laviada, I1
Enomoto, M1
Seong, JY1
Kawashima, S1
Park, MK1
Bading, JR2
Shahinian, AH2
Vail, A1
Bathija, P2
Koszalka, GW1
Koda, RT1
Alauddin, MM1
Fissekis, JD1
Conti, PS2
Hassan, S1
Dobner, PR1
Carraway, RE1
Sanford, DC1
DeWille, JW1
Peleg, S1
Dhawan, P1
Christakos, S1
Stewart, LV1
Weigel, NL2
Mehta, RG1
Holick, MF2
Bull, EE1
Dote, H1
Brady, KJ1
Burgan, WE1
Carter, DJ1
Cerra, MA1
Oswald, KA1
Hollingshead, MG1
Camphausen, K1
Tofilon, PJ1
Pandini, G1
Mineo, R1
Frasca, F1
Roberts, CT1
Marcelli, M1
Vigneri, R1
Belfiore, A1
Moro, L2
Arbini, AA2
Marra, E2
Greco, M2
Sun, P1
Xiong, H1
Kim, TH1
Ren, B1
Zhang, Z1
Drissi, A1
Bennani, H1
Giton, F1
Charrouf, Z1
Fiet, J1
Adlouni, A1
Agoulnik, IU1
Vaid, A1
Nakka, M1
Alvarado, M1
Bingman, WE1
Erdem, H1
Frolov, A1
Smith, CL1
Ayala, GE1
Ittmann, MM1
Alison, MR1
Wright, NA1
Meyer, JS1
Sufrin, G1
Martin, SA1
Ware, JL1
Paulson, DF1
Webb, KS2
Berdel, WE1
Fink, U1
Egger, B1
Reichert, A1
Munder, PG1
Rastetter, J1
Sandberg, AA1
Heston, WD1
Kadmon, D1
Fair, WR1
Wientjes, MG1
Pretlow, TG1
Badalament, RA1
Burgers, JK1
Au, JL1
Loop, SM1
Rozanski, TA1
Ostenson, RC1
Franzén, P1
Ichijo, H1
Miyazono, K1
Rowley, DR1
Dang, TD1
McBride, L1
Gerdes, MJ1
Lu, B1
Larsen, M1
August, EM1
Duncan, KL1
Malinowski, NM1
Cysyk, RL1
Igawa, M1
Tanabe, T1
Chodak, GW2
Rukstalis, DB1
Shah, GV2
Rayford, W2
Noble, MJ2
Austenfeld, M1
Weigel, J2
Vamos, S1
Mebust, WK2
Ewing, MW1
Liu, SC1
Gnarra, JR1
Walther, MM1
Meyers, CE1
Linehan, WM1
Hrzenjak, M1
Shain, SA1
Esquenet, M2
Swinnen, JV2
Heyns, W2
Verhoeven, G2
Stüben, J1
Port, R1
Bertram, B1
Bollow, U1
Hull, WE1
Schaper, M1
Pohl, J1
Wiessler, M1
Jamison, JM1
Gilloteaux, J1
Venugopal, M1
Koch, JA1
Sowick, C1
Shah, R1
Summers, JL1
Myers, RB1
Oelschlager, DK1
Hockett, RD1
Rogers, MD1
Conway-Myers, BA1
Austenfeld, MA1
Jungwirth, A1
Galvan, G1
Pinski, J1
Halmos, G1
Szepeshazi, K1
Cai, RZ1
Groot, K1
Schally, AV1
Maramag, C1
Menon, M1
Balaji, KC1
Reddy, PG1
Laxmanan, S1
Haberkorn, U1
Bellemann, ME1
Altmann, A1
Gerlach, L1
Morr, I1
Oberdorfer, F1
Brix, G1
Doll, J1
Blatter, J1
van Kaick, G1
Skryma, RN1
Prevarskaya, NB1
Dufy-Barbe, L1
Odessa, MF1
Audin, J1
Dufy, B1
Geller, J1
Sionit, L1
Partido, C1
Li, L1
Tan, X1
Youngkin, T1
Nachtsheim, D1
Hoffman, RM1
Bahk, JY1
Hyun, JS1
Lee, H1
Kim, MO1
Cho, GJ1
Lee, BH1
Choi, WS1
Fornaro, M1
Manzotti, M1
Tallini, G1
Slear, AE1
Bosari, S1
Ruoslahti, E1
Languino, LR1
Pflug, B1
Djakiew, D1
Lupowitz, Z2
Zisapel, N3
Mitchell, KO1
El-Deiry, WS1
Gilad, E1
Laufer, M1
Matzkin, H1
Sintich, SM1
Lamm, ML1
Sensibar, JA1
Lee, C2
Jongsma, J1
Oomen, MH1
Noordzij, MA1
Romijn, JC1
van Der Kwast, TH1
Schröder, FH1
van Steenbrugge, GJ1
Theodossiou, C1
Schwartz, GG1
Burnstein, KL1
Lokeshwar, BL1
Martin, JL1
Pattison, SL1
White, RA1
Meistrich, ML1
Pollack, A1
Terry, NH1
Matthews, E1
Yang, T1
Janulis, L1
Goodwin, S1
Kundu, SD1
Karpus, WJ1
Girnita, L1
Girnita, A1
Wang, M1
Meis-Kindblom, JM1
Kindblom, LG1
Larsson, O1
Yamabe, Y1
Hoshino, A1
Imura, N1
Suzuki, T1
Himeno, S1
Hillman, GG1
Forman, JD1
Kucuk, O1
Yudelev, M1
Maughan, RL1
Rubio, J1
Layer, A1
Tekyi-Mensah, S1
Abrams, J1
Sarkar, FH1
Rylova, SN1
Amalfitano, A1
Persaud-Sawin, DA1
Guo, WX1
Chang, J1
Jansen, PJ1
Proia, AD1
Boustany, RM1
Rho, YS1
Kim, SA1
Jung, JC1
Shin, CC1
Chang, SG1
Rimler, A1
Li, MT1
Richter, F1
Chang, C1
Irwin, RJ1
Huang, H1
Claflin, AJ1
Vesely, DL1
Hudson, JL1
Bagwell, CB1
Lehotay, DC1
Lo, TM1
Fletcher, MA1
Block, NL1
Levey, GS1
Boileau, M1
Keenan, E1
Kemp, E1
Lawson, R1
Hodges, CV1
Lasnitzki, I1
Ablin, RJ4
Guinan, PD3
Bruns, GR3
Sadoughi, N1
Bush, IM4
Al sheik, H1
Limonta, P1
Dondi, D1
Moretti, RM1
Maggi, R1
Motta, M1
Touffet, S1
Gayet, G1
Sampérez, S1
Jouan, P1
Chen, HZ1
Kirschenbaum, A1
Mandeli, J1
Hollander, VP1
Perkel, VS1
Mohan, S1
Herring, SJ1
Baylink, DJ1
Linkhart, TA1
Nakamoto, T1
Chang, CS1
Li, AK1
MacDonald, A1
Habib, FK1
Hayashi, N1
Cunha, GR1
Mobbs, BG1
Johnson, IE1
Pavelić, J1
Zgradić, I1
Pavelić, K1
Donaldson, JT1
Tucker, JA1
Keane, TE1
Walther, PJ1
Koutsilieris, M1
Rabbani, SA1
Goltzman, D1
Hierowski, MT1
McDonald, MW1
Dunn, L1
Sullivan, JW1
Kirchheimer, JC1
Wojta, J1
Hienert, G1
Christ, G1
Heger, ME1
Pflüger, H1
Binder, BR1
Kyprianou, N1
Isaacs, JT1
Wilding, G1
Zugmeier, G1
Knabbe, C1
Flanders, K1
Gelmann, E1
Citterio, F1
Kahan, BD1
Scott, FM1
Sator de Serrano, V1
Castellino, FJ1
Feminell, JG1
Tomashefsky, P1
Tannenbaum, M1
Lattimer, JK1
Faul, P3
Rabes, H3
Helpap, B2
Stiens, R2
Brühl, P1
Burns, GR1
Guinan, P1
McLaughlin, AP1
Brooks, JD1
Markewitz, M2
Veenema, RJ3
Fingerhut, B3
Gursel, E1
Huber, C1
Huber, H1
Gföller, A1
Michlamyr, G1
Braunsteiner, H1
Mackler, MA1
Liberti, JP1
Smith, MJ1
Koontz, WW1
Prout, GR1
Robinson, MR2
Nakhla, LS2
Whitaker, RH2
Chandley, AC1
Kofman-Alfaro, S1
Nehme-Haily, D1
Sommers, SC1
Graff, S1
Butler, MP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Non Interventional Post Authorisation Multicenter Study to Evaluate the Disease Control (Benign Prostate Hyperplasia Control) and Quality of Life (QoL) Following the 6-months Combination Treatment With Dutasteride and Tamsulosin. PROSPERITY Group of Stu[NCT04831476]1,296 participants (Actual)Observational2021-09-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for thymidine and Prostatic Neoplasms

ArticleYear
Prostate cancer. Growth kinetics.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1981, Volume: 78

    Topics: Adenocarcinoma; Animals; Cell Division; DNA Replication; DNA, Neoplasm; Humans; Jejunum; Kinetics; M

1981
[Demonstration of thymidine phosphorylase activity in human healthy, adenomatous and cancerous prostate].
    Bulletin du cancer, 1992, Volume: 79, Issue:2

    Topics: Humans; Male; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Thymidine; Thymidine Phosphoryla

1992

Other Studies

111 other studies available for thymidine and Prostatic Neoplasms

ArticleYear
Analytical and clinical characterization of an optimized dual monoclonal sandwich ELISA for the quantification of thymidine kinase 1 (TK1) protein in human blood samples.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Breast Neoplasms; DNA; Enzyme-Linked Immunosorbent Assay;

2022
Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2013, Nov-15, Volume: 20, Issue:14

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Line; Ce

2013
Estrogen receptor beta (ERβ) mediates expression of β-catenin and proliferation in prostate cancer cell line PC-3.
    Molecular and cellular endocrinology, 2016, 07-15, Volume: 430

    Topics: beta Catenin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin D2; Cycloheximide; Estradiol;

2016
Dihydrotestosterone sensitises LNCaP cells to death induced by epigallocatechin-3-Gallate (EGCG) or an IGF-I receptor inhibitor.
    The Prostate, 2009, Feb-01, Volume: 69, Issue:2

    Topics: Blotting, Western; Catechin; Cell Death; Cell Line, Tumor; Dihydrotestosterone; DNA Replication; DNA

2009
Facile synthesis and anti-tumor cell activity of Se-containing nucleosides.
    Nucleosides, nucleotides & nucleic acids, 2009, Volume: 28, Issue:1

    Topics: Cell Line, Tumor; Cells, Cultured; Deoxyuridine; Drug Screening Assays, Antitumor; Humans; Male; Pro

2009
Biochemical characterization of riboflavin carrier protein (RCP) in prostate cancer.
    Frontiers in bioscience (Landmark edition), 2009, 01-01, Volume: 14, Issue:10

    Topics: Amino Acid Sequence; Blotting, Western; Cell Line, Tumor; Humans; Immunohistochemistry; Immunoprecip

2009
The pure anti-androgen bicalutamide inhibits cyclin A expression both in androgen-dependent and -independent cell lines.
    International journal of oncology, 2010, Volume: 36, Issue:3

    Topics: Androgen Antagonists; Androgens; Anilides; Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tu

2010
Expression and function of ATIP/MTUS1 in human prostate cancer cell lines.
    The Prostate, 2010, Oct-01, Volume: 70, Issue:14

    Topics: Cell Line, Tumor; DNA Primers; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Huma

2010
ICER reverses tumorigenesis of rat prostate tumor cells without affecting cell growth.
    The Prostate, 2002, Nov-01, Volume: 53, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Assay; Blotting, Western; Cell Cycle; Ce

2002
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Actin Depolymerizing Factors; Cell Division; Cell Line; Cell Line, Tumor; Cell Separation; DNA; DNA-

2003
1alpha,25-Dihydroxyvitamin D3-3beta-(2)-bromoacetate, an affinity labeling derivative of 1alpha,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells.
    Journal of cellular biochemistry, 2003, Aug-01, Volume: 89, Issue:5

    Topics: Affinity Labels; Apoptosis; Breast Neoplasms; Calcitriol; Cell Division; Cell Line; Cell Survival; D

2003
BASIC STUDIES ON THE PROSTATE OF RAT UNDER VARIOUS HORMONAL ENVIRONMENT.
    Endocrinologia japonica, 1965, Volume: 12

    Topics: Alloxan; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cortisone; Estradio

1965
IGF-I and MAP kinase involvement in the stimulatory effects of LNCaP prostate cancer cell conditioned media on cell proliferation and protein synthesis in MC3T3-E1 osteoblastic cells.
    Journal of cellular biochemistry, 2003, Dec-01, Volume: 90, Issue:5

    Topics: Animals; Cell Division; Culture Media, Conditioned; Enzyme Inhibitors; Humans; Insulin-Like Growth F

2003
Enhancement of androgen receptor expression induced by (R)-methanandamide in prostate LNCaP cells.
    FEBS letters, 2003, Dec-18, Volume: 555, Issue:3

    Topics: Androgen Receptor Antagonists; Arachidonic Acids; Cannabinoids; Cell Division; Cell Line, Tumor; DNA

2003
Proliferation of TSU-Pr1, a human prostatic carcinoma cell line is stimulated by gonadotropin-releasing hormone.
    Life sciences, 2004, May-07, Volume: 74, Issue:25

    Topics: Cell Division; Colony-Forming Units Assay; Culture Media, Conditioned; Fertility Agents, Female; Gon

2004
Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats.
    Nuclear medicine and biology, 2004, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Animals; Arabinofuranosyluracil; Carbon Radioisotopes; Cell Line, Tumor; Colorectal

2004
Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells.
    Regulatory peptides, 2004, Aug-15, Volume: 120, Issue:1-3

    Topics: Blotting, Western; DNA, Neoplasm; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Liga

2004
C/EBPdelta is a downstream mediator of IL-6 induced growth inhibition of prostate cancer cells.
    The Prostate, 2005, May-01, Volume: 63, Issue:2

    Topics: Binding Sites; Blotting, Northern; Blotting, Western; CCAAT-Enhancer-Binding Protein-delta; CCAAT-En

2005
Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Apoptosis; Calcitriol; Carrier Proteins; Caspases

2004
Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Administration, Oral; Animals; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Com

2004
Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells.
    Cancer research, 2005, Mar-01, Volume: 65, Issue:5

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Cell Line, Tumor; Cell Mov

2005
Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: BRCA2 Protein; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Collagen Type I; DNA; DNA Repair

2005
Positive inter-regulation between beta-catenin/T cell factor-4 signaling and endothelin-1 signaling potentiates proliferation and survival of prostate cancer cells.
    Molecular pharmacology, 2006, Volume: 69, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Cell Proliferation; Endothelin

2006
Tocopherols and saponins derived from Argania spinosa exert, an antiproliferative effect on human prostate cancer.
    Cancer investigation, 2006, Volume: 24, Issue:6

    Topics: 2-Methoxyestradiol; Antioxidants; Cell Proliferation; Estradiol; Humans; Male; Neoplasms, Hormone-De

2006
Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer.
    Cancer research, 2006, Nov-01, Volume: 66, Issue:21

    Topics: Androgens; Cell Line, Tumor; Cell Proliferation; Exons; Humans; Immunohistochemistry; Introns; Male;

2006
Constitutive activation of MAPK/ERK inhibits prostate cancer cell proliferation through upregulation of BRCA2.
    International journal of oncology, 2007, Volume: 30, Issue:1

    Topics: BRCA2 Protein; Cell Adhesion; Cell Division; Cell Line, Tumor; Enzyme Activation; Extracellular Sign

2007
[DNA metabolism of prostate. II. DNA metabolism of experimental prostatic tumors].
    Hinyokika kiyo. Acta urologica Japonica, 1966, Volume: 12, Issue:3

    Topics: Animals; Autoradiography; DNA; Male; Methylcholanthrene; Neoplasms, Experimental; Prostatic Neoplasm

1966
Proliferative activity of benign human prostate, prostatic adenocarcinoma and seminal vesicle evaluated by thymidine labeling.
    The Journal of urology, 1982, Volume: 128, Issue:6

    Topics: Adenocarcinoma; Aged; Autoradiography; Cell Division; Cell Nucleus; Humans; Male; Prostate; Prostati

1982
1,10-Phenanthroline reversibility inhibits proliferation of two human prostate carcinoma cell lines (PC-3 and DU145).
    Biochemical and biophysical research communications, 1984, Oct-30, Volume: 124, Issue:2

    Topics: Antigens, Surface; Cell Division; Cell Line; DNA Replication; Epitopes; Humans; Kinetics; Male; Phen

1984
Inhibition by alkyl-lysophospholipids of tritiated thymidine uptake in cells of human malignant urologic tumors.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:5

    Topics: Cell Division; Cells, Cultured; Humans; Lysophosphatidylcholines; Male; Prostatic Neoplasms; Teratom

1981
Rationale and practice of testing chemotherapeutic agents for prostate cancer.
    Urology, 1981, Volume: 17, Issue:4 Suppl

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adenocarcinoma; Animals; Antineoplastic Agents; Arginase; DNA

1981
Effect of high dose diethylstilbestrol and ICRF-159 on the growth and metastases of the R3327 MAT-LyLu prostate-derived tumor.
    Cancer letters, 1981, Volume: 13, Issue:2

    Topics: Animals; Diethylstilbestrol; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasms, Experimental; Pi

1981
Histocultures of human prostate tissues for pharmacologic evaluation.
    The Journal of urology, 1995, Volume: 153, Issue:4

    Topics: Acid Phosphatase; Cell Division; Culture Techniques; Drug Screening Assays, Antitumor; Humans; Immun

1995
Human primary prostate tumor cell line, ALVA-31: a new model for studying the hormonal regulation of prostate tumor cell growth.
    The Prostate, 1993, Volume: 22, Issue:2

    Topics: Acid Phosphatase; Animals; Biomarkers; Cell Division; Cytosol; Female; Humans; Isoenzymes; Karyotypi

1993
Different signals mediate transforming growth factor-beta 1-induced growth inhibition and extracellular matrix production in prostatic carcinoma cells.
    Experimental cell research, 1993, Volume: 207, Issue:1

    Topics: Cell Division; Clone Cells; Drug Resistance; Fibronectins; Fibrosis; Genes, jun; Humans; Male; Plasm

1993
Beta-2 microglobulin is mitogenic to PC-3 prostatic carcinoma cells and antagonistic to transforming growth factor beta 1 action.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: beta 2-Microglobulin; Cell Division; Culture Media; Humans; Kinetics; Male; Mitogens; Prostate; Pros

1995
Inhibition of fibroblast hyaluronic acid production by suramin.
    Oncology research, 1993, Volume: 5, Issue:10-11

    Topics: 3T3 Cells; Animals; Cell Division; Culture Media; DNA; Dose-Response Relationship, Drug; Fibroblasts

1993
N-(4-hydroxyphenyl) retinamide induces cell cycle specific growth inhibition in PC3 cells.
    The Prostate, 1994, Volume: 24, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Blotting, Northern; Cell Cycle; Cell Division; Cell Line; DNA

1994
Calcitonin stimulates growth of human prostate cancer cells through receptor-mediated increase in cyclic adenosine 3',5'-monophosphates and cytoplasmic Ca2+ transients.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: Adenocarcinoma; Calcitonin; Calcium; Cell Division; Cell Line; Cell Membrane; Cyclic AMP; Cytoplasm;

1994
Effect of suramin on the mitogenic response of the human prostate carcinoma cell line PC-3.
    Cancer, 1993, Feb-01, Volume: 71, Issue:3 Suppl

    Topics: Blotting, Northern; Cell Cycle; Cell Division; Culture Media, Serum-Free; Dose-Response Relationship

1993
Protein kinase C-dependent and -independent pathways of signal transduction in prostate cancer cells: fibroblast growth factor utilization of a protein kinase C-independent pathway.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:9

    Topics: Animals; Cell Division; Down-Regulation; Fibroblast Growth Factor 1; Fibroblast Growth Factors; Male

1995
Control of LNCaP proliferation and differentiation: actions and interactions of androgens, 1alpha,25-dihydroxycholecalciferol, all-trans retinoic acid, 9-cis retinoic acid, and phenylacetate.
    The Prostate, 1996, Volume: 28, Issue:3

    Topics: Androgens; Antimetabolites, Antineoplastic; Calcitriol; Cell Differentiation; Cell Division; Humans;

1996
Pharmacokinetics and whole-body distribution of the new chemotherapeutic agent beta-D-glucosylisophosphoramide mustard and its effects on the incorporation of [methyl-3H]-thymidine in various tissues of the rat.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:4

    Topics: Animals; Antineoplastic Agents; Autoradiography; Bile; DNA, Neoplasm; Female; Glucose; Half-Life; Hu

1996
Flow cytometric and ultrastructural aspects of the synergistic antitumor activity of vitamin C-vitamin K3 combinations against human prostatic carcinoma cells.
    Tissue & cell, 1996, Volume: 28, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; DNA; Drug Synergism; Flow Cytometry;

1996
The effects of dihydrotestosterone on the expression of p185(erbB-2) and c-erbB-2 mRNA in the prostatic cell line LNCaP.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:5-6

    Topics: Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Prot

1996
Muscarinic cholinergic receptors promote growth of human prostate cancer cells.
    The Prostate, 1997, Feb-15, Volume: 30, Issue:3

    Topics: Bromodeoxyuridine; Carbachol; DNA, Neoplasm; Humans; Immunohistochemistry; Male; Prostatic Neoplasms

1997
Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude mice.
    The Prostate, 1997, Aug-01, Volume: 32, Issue:3

    Topics: Animals; Antineoplastic Agents; Bombesin; Cell Division; DNA, Neoplasm; Drug Combinations; ErbB Rece

1997
Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis.
    The Prostate, 1997, Aug-01, Volume: 32, Issue:3

    Topics: Androgens; Antineoplastic Agents; Ascorbic Acid; Azides; Cell Count; Cell Survival; DNA, Neoplasm; D

1997
PET 2-fluoro-2-deoxyglucose uptake in rat prostate adenocarcinoma during chemotherapy with gemcitabine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:8

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biological Transport; Deoxycytidine; Deoxy

1997
Potassium conductance in the androgen-sensitive prostate cancer cell line, LNCaP: involvement in cell proliferation.
    The Prostate, 1997, Oct-01, Volume: 33, Issue:2

    Topics: Androgens; Apoptosis; Calcium; Cell Division; Elapid Venoms; Humans; Male; Membrane Potentials; Patc

1997
LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:5-6

    Topics: Acid Phosphatase; Calcitriol; Carrier Proteins; Cell Division; Diazepam Binding Inhibitor; ErbB Rece

1997
Genistein inhibits the growth of human-patient BPH and prostate cancer in histoculture.
    The Prostate, 1998, Feb-01, Volume: 34, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Genistein;

1998
Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells.
    Urological research, 1998, Volume: 26, Issue:4

    Topics: Cell Division; Gene Expression; Gonadotropin-Releasing Hormone; Humans; In Situ Hybridization; Male;

1998
Beta1C integrin in epithelial cells correlates with a nonproliferative phenotype: forced expression of beta1C inhibits prostate epithelial cell proliferation.
    The American journal of pathology, 1998, Volume: 153, Issue:4

    Topics: Alternative Splicing; Bile Ducts; Cell Division; Embryonic and Fetal Development; Epithelial Cells;

1998
Expression of p75NTR in a human prostate epithelial tumor cell line reduces nerve growth factor-induced cell growth by activation of programmed cell death.
    Molecular carcinogenesis, 1998, Volume: 23, Issue:2

    Topics: Apoptosis; Cell Division; Humans; Male; Nerve Growth Factors; Prostatic Neoplasms; Receptor, Nerve G

1998
Hormonal interactions in human prostate tumor LNCaP cells.
    The Journal of steroid biochemistry and molecular biology, 1999, Volume: 68, Issue:1-2

    Topics: Androgens; Cell Division; Cell Survival; Drug Interactions; Estradiol; Humans; Male; Melatonin; Neop

1999
Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1999, Volume: 10, Issue:4

    Topics: Adenoviridae; Apoptosis; Blotting, Western; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Cycl

1999
Melatonin receptors in PC3 human prostate tumor cells.
    Journal of pineal research, 1999, Volume: 26, Issue:4

    Topics: Binding Sites; Cell Count; Cell Survival; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Ki

1999
Transforming growth factor-beta1-induced proliferation of the prostate cancer cell line, TSU-Pr1: the role of platelet-derived growth factor.
    Endocrinology, 1999, Volume: 140, Issue:8

    Topics: Becaplermin; Cell Division; DNA, Neoplasm; Humans; Kinetics; Male; Platelet-Derived Growth Factor; P

1999
Androgen-independent growth is induced by neuropeptides in human prostate cancer cell lines.
    The Prostate, 2000, Volume: 42, Issue:1

    Topics: Androgens; Cell Division; Cyclic AMP; Dideoxyadenosine; Enzyme Inhibitors; Gastrin-Releasing Peptide

2000
Propylthiouracil reduces xenograft tumor growth in an athymic nude mouse prostate cancer model.
    The American journal of the medical sciences, 2000, Volume: 319, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Contrast Media; Disease Models, Animal; Humans; Hypothyroi

2000
The in vitro evaluation of 25-hydroxyvitamin D3 and 19-nor-1alpha,25-dihydroxyvitamin D2 as therapeutic agents for prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Calcifediol; Cell Count; Cell Division; Chloramphenicol O-Acetyltransferase; Dose-Response Relations

2000
Insulin-like growth factor binding protein-3 is regulated by dihydrotestosterone and stimulates deoxyribonucleic acid synthesis and cell proliferation in LNCaP prostate carcinoma cells.
    Endocrinology, 2000, Volume: 141, Issue:7

    Topics: Cell Division; Dihydrotestosterone; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Combi

2000
Pharmacokinetics of the thymidine analog 2'-fluoro-5-[(14)C]-methyl-1-beta-D-arabinofuranosyluracil ([(14)C]FMAU) in rat prostate tumor cells.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:4

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; DNA; Male; Prostatic Neoplasms; Rats; Thymidine;

2000
Simultaneous estimation of T(G2+M), T(S), and T(pot) using single sample dynamic tumor data from bivariate DNA-thymidine analogue cytometry.
    Cytometry, 2000, Sep-01, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; DNA, Neoplasm; Female

2000
Down-regulation of TGF-beta1 production restores immunogenicity in prostate cancer cells.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Animals; Cell Division; Cloning, Molecular; Disease Progression; DNA, Complementary; Down-Regulation

2000
A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cells.
    Oncogene, 2000, Aug-31, Volume: 19, Issue:37

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Bone Neoplasms; Cell Cycle; Cell Division; Chromosomes, Huma

2000
Enhancement of androgen-dependent transcription and cell proliferation by tributyltin and triphenyltin in human prostate cancer cells.
    Toxicology and applied pharmacology, 2000, Dec-01, Volume: 169, Issue:2

    Topics: Androgen Antagonists; Androgens; Blotting, Northern; Cell Division; DNA, Neoplasm; Flutamide; Humans

2000
Genistein potentiates the radiation effect on prostate carcinoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cell Survival; DNA; DNA, Neoplasm; Gamma Rays; Geni

2001
The CLN3 gene is a novel molecular target for cancer drug discovery.
    Cancer research, 2002, Feb-01, Volume: 62, Issue:3

    Topics: Adenoviridae; Animals; Apoptosis; Ceramides; Colonic Neoplasms; DNA, Antisense; Gene Expression Regu

2002
Anticancer cytotoxicity and nephrotoxicity of the new platinum (II) complexes containing diaminocyclohexane and glycolic acid.
    International journal of oncology, 2002, Volume: 20, Issue:5

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Coloring Agents; Cyclohexanes; DNA; Female; Glucose

2002
Differential regulation by melatonin of cell growth and androgen receptor binding to the androgen response element in prostate cancer cells.
    Neuro endocrinology letters, 2002, Volume: 23 Suppl 1

    Topics: Antioxidants; Cell Cycle; DNA; Electrophoresis; Flow Cytometry; Humans; Male; Melatonin; Mutation; P

2002
Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor.
    BMC cancer, 2002, Jun-10, Volume: 2

    Topics: Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; ErbB Rece

2002
Inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (Momordica charantia abbreviata).
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Cycle; Concanavalin A; Cyclic GMP; Guanylate Cyclase; In Vitro Techniq

1978
The effect of human serum on 3H-thymidine incorporation in human prostate tumors in tissue culture.
    The Journal of urology, 1978, Volume: 119, Issue:6

    Topics: Animals; Blood; Cattle; Culture Techniques; Dihydrotestosterone; DNA; Humans; Male; Prostatic Hyperp

1978
Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues.
    British journal of cancer, 1976, Volume: 34, Issue:3

    Topics: Animals; DNA; Hyperplasia; In Vitro Techniques; Male; Metaplasia; Methylcholanthrene; Mice; Mice, In

1976
Serum proteins in prostatic cancer. II. Effect on in vitro cell-mediated immunologic responsiveness.
    Urology, 1975, Volume: 6, Issue:1

    Topics: Antilymphocyte Serum; Blood Proteins; Cell Migration Inhibition; Cells, Cultured; Culture Media; Hum

1975
Hormonal therapy and alteration of lymphocyte proliferation.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:2

    Topics: Estrogens; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Male; Penile Induration; Prostatic N

1976
Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 75, Issue:1

    Topics: Antineoplastic Agents; Binding Sites; Buserelin; Gonadotropin-Releasing Hormone; Goserelin; Humans;

1992
The effect of dihydrotestosterone and culture conditions on proliferation of the human prostatic cancer cell line LNCaP.
    Steroids, 1992, Volume: 57, Issue:6

    Topics: Biological Factors; Cell Count; Cell Division; Culture Media, Serum-Free; Dihydrotestosterone; Human

1992
Human prostatic cancer cells, PC3, elaborate mitogenic activity which selectively stimulates human bone cells.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Animals; Bone and Bones; Cell Division; Cells, Cultured; Chromatography, Gel; Culture Media; Dextran

1990
Basic fibroblast growth factor in human prostate cancer cells.
    Cancer research, 1992, Feb-01, Volume: 52, Issue:3

    Topics: 3T3 Cells; Animals; Biological Assay; Blotting, Northern; Blotting, Southern; Cattle; Cell Division;

1992
Divergent responses to epidermal growth factor in hormone sensitive and insensitive human prostate cancer cell lines.
    British journal of cancer, 1992, Volume: 65, Issue:2

    Topics: Blotting, Western; Cell Division; DNA, Neoplasm; Epidermal Growth Factor; ErbB Receptors; Humans; Ma

1992
Mesenchyme-induced changes in the neoplastic characteristics of the Dunning prostatic adenocarcinoma.
    Cancer research, 1991, Sep-15, Volume: 51, Issue:18

    Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Electrophoresis, Poly

1991
Suppression of the growth of the androgen-insensitive R3327 HI rat prostatic carcinoma by combined estrogen and antiprogestin treatment.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:5A

    Topics: Animals; Cell Division; Cell Line; Diethylstilbestrol; DNA Replication; Drug Interactions; Male; Mif

1991
Presence of oestrogen receptors on target cells and antiproliferative activity of estramustine phosphate: positive correlation for human tumours in vitro.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:3

    Topics: Cell Division; Cytosol; DNA, Neoplasm; Dose-Response Relationship, Drug; Estramustine; Female; Human

1991
Characterization of a new model of human prostatic cancer: the multicellular tumor spheroid.
    International journal of cancer, 1990, Aug-15, Volume: 46, Issue:2

    Topics: Antineoplastic Agents; Cell Line; Cell Separation; Drug Screening Assays, Antitumor; Flow Cytometry;

1990
Selective osteoblast mitogens can be extracted from prostatic tissue.
    The Prostate, 1986, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Fibroblasts; Growth Substances; Humans; Male; Mit

1986
The partial dependency of human prostatic growth factor on steroid hormones in stimulating thymidine incorporation into DNA.
    The Journal of urology, 1987, Volume: 138, Issue:4

    Topics: Adult; Aged; Dihydrotestosterone; DNA; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Estradiol

1987
Effect of urokinase on the proliferation of primary cultures of human prostatic cells.
    Thrombosis research, 1987, Nov-01, Volume: 48, Issue:3

    Topics: Cell Division; Cells, Cultured; DNA Replication; Fibrinolysin; Humans; Kinetics; Male; Prostate; Pro

1987
"Thymineless" death in androgen-independent prostatic cancer cells.
    Biochemical and biophysical research communications, 1989, Nov-30, Volume: 165, Issue:1

    Topics: Animals; Blotting, Northern; Cell Line; Cell Survival; DNA, Neoplasm; Drug Screening Assays, Antitum

1989
Differential effects of transforming growth factor beta on human prostate cancer cells in vitro.
    Molecular and cellular endocrinology, 1989, Volume: 62, Issue:1

    Topics: Androgens; Cell Adhesion; Cell Division; Humans; Male; Prostatic Neoplasms; Protein Biosynthesis; Pr

1989
Specificity of the nuclear effect of cyclosporine on the immune cells.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 1

    Topics: Adenocarcinoma; Animals; Cell Line; Cell Nucleus; Cyclosporins; DNA Replication; Kidney; Liver; Lymp

1989
Appearance of plasminogen activator activity during a synchronous cycle of a rat adenocarcinoma cell line, PA-III.
    Experimental cell research, 1987, Volume: 169, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Line; Clone Cells; DNA Replication; Hydroxyurea; Kinetics;

1987
Differences in regeneration of the prostate after cryoprostatectomy, fulguration and excision.
    Transactions of the American Association of Genito-Urinary Surgeons, 1970, Volume: 62

    Topics: Animals; Autoradiography; Cryosurgery; DNA; Electrosurgery; Male; Metaplasia; Organ Size; Prostate;

1970
[Thymidine- 3 H autoradiography of human prostate cytological biopsy specimens].
    Der Urologe. Ausg. A, 1972, Volume: 11, Issue:5

    Topics: Autoradiography; Biopsy, Needle; Carcinoma; Culture Techniques; Diethylstilbestrol; DNA; Glycogen; H

1972
[Autoradiographic in vitro investigations on prostatic tissue with the C-14- und H-3-thymidine double-labeling method (author's transl)].
    Beitrage zur Pathologie, 1974, Volume: 151, Issue:1

    Topics: Adenocarcinoma; Aged; Atrophy; Autoradiography; Biopsy, Needle; Carbon Radioisotopes; Carcinoma; DNA

1974
Letter: Afferent blockage, oestrogenic therapy, and malignancy.
    Lancet (London, England), 1974, Aug-17, Volume: 2, Issue:7877

    Topics: Adult; Cell Transformation, Neoplastic; Estrogens; Female; Humans; Immunity, Cellular; Lectins; Lymp

1974
[Determination of proliferative activity of human prostatic needle biopsies by means of 3H-thymidine autoradiography (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1973, Volume: 57

    Topics: Autoradiography; Biopsy, Needle; Carcinoma; Cell Division; Cells, Cultured; Humans; Male; Prostatic

1973
Antiandrogenic suppression of lymphocytic blastogenesis: in vitro and in vivo observations.
    Experientia, 1974, Nov-15, Volume: 30, Issue:11

    Topics: Adolescent; Adult; Androgen Antagonists; Antibody Formation; Cell Transformation, Neoplastic; Diethy

1974
[The significance of cell kinetics in the treatment of malignant tumours (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Sep-13, Volume: 99, Issue:37

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Autoradiography; Bronchial Neoplasms; Carcinoma, Squ

1974
A plasma factor inhibiting lymphocyte reactivity in urologic cancer patients.
    The Journal of urology, 1974, Volume: 112, Issue:3

    Topics: Adenocarcinoma; Analysis of Variance; Cells, Cultured; Female; Humans; Immune Sera; Immunity, Cellul

1974
[Thymidine-3H autoradiography in human cytological prostate puncture material].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1972, Volume: 78

    Topics: Autoradiography; Biopsy, Needle; Humans; Male; Prostatic Neoplasms; Thymidine; Tritium

1972
Testicular morphology and germ cell DNA synthesis in the testis of patients with prostatic carcinoma.
    Cancer, 1971, Volume: 27, Issue:4

    Topics: Acid Phosphatase; Aged; Atrophy; Biopsy; Carcinoma; DNA; Follicle Stimulating Hormone; Gonadotropins

1971
[DNS synthesizing lymphocytes in patients with carcinoma].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Autoradiography; Blood Cell Count; Breast Neoplasms; Bronchial Neoplasms; DNA, Neoplasm; Female; His

1971
The effect of orchiectomy and various doses of stilbestrol on plasma testosterone levels in patients with carcinoma of the prostate.
    Investigative urology, 1972, Volume: 9, Issue:5

    Topics: Castration; Diethylstilbestrol; Humans; Male; Prostatic Neoplasms; Protein Binding; Testis; Testoste

1972
Lymphocyte transformation inb carcinoma of the prostate.
    British journal of urology, 1971, Volume: 43, Issue:4

    Topics: Acid Phosphatase; Aged; Culture Techniques; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Mal

1971
"Unscheduled" DNA synthesis in human germ cells following UV irradiation.
    Experimental cell research, 1971, Volume: 69, Issue:1

    Topics: Adult; Aged; Autoradiography; Biopsy; Cells, Cultured; DNA; Histocytochemistry; Humans; Male; Meiosi

1971
A new concept in the management of carcinoma of the prostate.
    British journal of urology, 1971, Volume: 43, Issue:6

    Topics: Aged; Biopsy; Carcinoma; Humans; Immune Sera; Immunization, Passive; Lectins; Lymphocyte Activation;

1971
Cyproterone acetate (SH 714) effect on histology and nucleic acid synthesis in the testes of patients with prostatic carcinoma. A preliminary report.
    Investigative urology, 1969, Volume: 6, Issue:6

    Topics: Adenocarcinoma; Aged; Biopsy; DNA; Humans; Leydig Cells; Male; Nucleic Acids; Progestins; Prostatic

1969
Observations on RNA in prostate and bladder neoplasms.
    The Journal of urology, 1969, Volume: 101, Issue:4

    Topics: Animals; Histocytochemistry; Humans; In Vitro Techniques; Male; Nucleosides; Prostatic Neoplasms; Ra

1969