thymidine has been researched along with Pituitary Neoplasms in 35 studies
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human pituitary adenoma cells and rat pituitary cell line (GH3) were cultured and treated in vitro with octreotide and the broad-spectrum SST agonist SOM230 (pasireotide)." | 3.73 | Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours. ( Ciccarelli, E; Czirják, S; Gaia, D; Góth, MI; Grossman, AB; Hanson, MR; Hanzély, Z; Hubina, E; Jordan, S; Khalaf, S; Korbonits, M; Losa, M; Nagy, GM; Nanzer, AM; Papotti, M; Terreni, MR, 2006) |
| " The effect of inhibition of tyrosine kinase activity on thymidine uptake into cultured human pituitary adenoma cells was studied using two inhibitors, genestein and methyl-2,3-dihydroxycinnamate (MDHC)." | 3.69 | Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells. ( Jones, TH; Justice, SK; Price, A, 1997) |
| "Among these, the growth fraction of pituitary adenomas has been determined by different methods, of which the most useful are those performed in archival material." | 1.30 | Usefulness of markers of cell proliferation in the management of pituitary adenomas. ( Franzin, A; Giovanelli, M; Losa, M; Mangili, F; Mortini, P; Terreni, MR, 1998) |
| "The most effective therapy of human prolactinomas is represented by dopamine D-2 receptor agonists; there is, however, a population of nonresponder patients who require surgical intervention." | 1.29 | Nerve growth factor suppresses the transforming phenotype of human prolactinomas. ( Balsari, A; Boroni, F; Dal Toso, R; Giovanelli, M; Losa, M; Missale, C; Spano, P; Zanellato, A, 1993) |
| " To determine whether the inabilities of TAM to stimulate cell proliferation and induce PR were a function of TAM concentration, dose-response experiments were performed." | 1.28 | The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific. ( Baldwin, TM; Beams, FE; Gilchrist, CA; Hrbek, MJ; Shull, JD, 1992) |
| "MtT/W15 transplantable pituitary tumors from rats treated for 3 weeks with DES showed significant reduction in the extent of [3H]thymidine incorporation compared with tumor cells from untreated rats (2231 +/- 182 vs 172 +/- 17 dpm/10(5) cells; n = 3)." | 1.27 | Prolactin and growth hormone synthesis and thymidine incorporation in dissociated rat pituitary tumor cells. ( Coleman, K; Lloyd, RV; Schmidt, K; Wilson, BS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (42.86) | 18.7374 |
| 1990's | 16 (45.71) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Florio, T | 2 |
| Barbieri, F | 1 |
| Spaziante, R | 2 |
| Zona, G | 2 |
| Hofland, LJ | 1 |
| van Koetsveld, PM | 1 |
| Feelders, RA | 1 |
| Stalla, GK | 1 |
| Theodoropoulou, M | 1 |
| Culler, MD | 2 |
| Dong, J | 1 |
| Taylor, JE | 1 |
| Moreau, JP | 1 |
| Saveanu, A | 2 |
| Gunz, G | 1 |
| Dufour, H | 1 |
| Jaquet, P | 2 |
| Hubina, E | 1 |
| Nanzer, AM | 1 |
| Hanson, MR | 1 |
| Ciccarelli, E | 1 |
| Losa, M | 3 |
| Gaia, D | 1 |
| Papotti, M | 1 |
| Terreni, MR | 2 |
| Khalaf, S | 1 |
| Jordan, S | 1 |
| Czirják, S | 1 |
| Hanzély, Z | 1 |
| Nagy, GM | 1 |
| Góth, MI | 1 |
| Grossman, AB | 1 |
| Korbonits, M | 1 |
| Resmini, E | 1 |
| Dadati, P | 1 |
| Ravetti, JL | 1 |
| Bianchi, F | 1 |
| Rebora, A | 1 |
| Minuto, F | 1 |
| Ferone, D | 1 |
| Svec, F | 1 |
| Pharaboz, MO | 1 |
| Morel, Y | 1 |
| Andre, J | 1 |
| Senogles, SE | 1 |
| Caronti, B | 1 |
| Palladini, G | 1 |
| Calderaro, C | 1 |
| Bevilacqua, MG | 1 |
| Petrangeli, E | 1 |
| Esposito, V | 1 |
| Tamburrano, G | 1 |
| Gulino, A | 1 |
| Jaffrain-Rea, ML | 1 |
| Kunert-Radek, J | 1 |
| Stepień, H | 1 |
| Pawlikowski, M | 1 |
| Alvarez, CV | 1 |
| Zalvide, JB | 1 |
| Cancio, E | 1 |
| Dieguez, C | 1 |
| Regueiro, BJ | 1 |
| Vega, FV | 1 |
| Dominguez, F | 1 |
| Missale, C | 1 |
| Boroni, F | 1 |
| Giovanelli, M | 2 |
| Zanellato, A | 1 |
| Dal Toso, R | 1 |
| Balsari, A | 1 |
| Spano, P | 1 |
| Lewis, MD | 1 |
| Webster, J | 1 |
| Ham, J | 1 |
| Davies, JS | 1 |
| Scanlon, MF | 1 |
| Jones, TH | 1 |
| Justice, SK | 1 |
| Price, A | 1 |
| Honegger, J | 1 |
| Renner, C | 1 |
| Fahlbusch, R | 1 |
| Adams, EF | 1 |
| Díaz-Torga, G | 1 |
| González Iglesias, A | 1 |
| Achával-Zaia, R | 1 |
| Libertun, C | 1 |
| Becú-Villalobos, D | 1 |
| Franzin, A | 1 |
| Mortini, P | 1 |
| Mangili, F | 1 |
| Li, H | 1 |
| Robinson, PJ | 1 |
| Kawashima, S | 1 |
| Funder, JW | 1 |
| Liu, JP | 1 |
| Danila, DC | 1 |
| Inder, WJ | 1 |
| Zhang, X | 1 |
| Alexander, JM | 1 |
| Swearingen, B | 1 |
| Hedley-Whyte, ET | 1 |
| Klibanski, A | 1 |
| Biswas, DK | 2 |
| Lyons, J | 1 |
| Tashjian, AH | 1 |
| Abdullah, KT | 1 |
| Brennessel, BA | 1 |
| Pan, MG | 1 |
| Newman, B | 1 |
| Hershberger, RE | 1 |
| Civelli, O | 1 |
| Stork, PJ | 1 |
| Duchemin, AM | 1 |
| Enyeart, JA | 1 |
| Biagi, BA | 1 |
| Foster, DN | 1 |
| Mlinar, B | 1 |
| Enyeart, JJ | 1 |
| Shull, JD | 1 |
| Beams, FE | 1 |
| Baldwin, TM | 1 |
| Gilchrist, CA | 1 |
| Hrbek, MJ | 1 |
| Reynolds, AM | 1 |
| Surks, MI | 2 |
| Shapiro, LE | 2 |
| Mackanos, EA | 1 |
| Pettit, GR | 1 |
| Ramsdell, JS | 1 |
| Melmed, S | 1 |
| Fagin, J | 1 |
| Leung, M | 1 |
| Patel, KR | 1 |
| Lloyd, RV | 1 |
| Schmidt, K | 1 |
| Coleman, K | 1 |
| Wilson, BS | 1 |
| Boeryd, B | 1 |
| Eriksson, O | 1 |
| Knutson, F | 1 |
| Lundin, PM | 1 |
| Norrby, K | 1 |
| Dingemans, KP | 1 |
| Biswas, S | 1 |
| Hollander, VP | 1 |
| Church, RL | 1 |
| Consigli, RA | 1 |
| Vanha-Perttula, T | 1 |
| Kohler, PO | 1 |
| Frohman, LA | 1 |
| Messier, B | 2 |
| Clifton, KH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Value of 3 Months Results on 12 Months Tumor Shrinkage After First-Line Octreotide-LAR Therapy in Patients With Acromegaly[NCT00616408] | 61 participants (Actual) | Observational | 1997-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
35 other studies available for thymidine and Pituitary Neoplasms
| Article | Year |
|---|---|
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
Topics: Adenoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cabergoline; Cell Division; Dopamine; Dopamin | 2008 |
Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours.
Topics: Adenoma; Animals; Antineoplastic Agents, Hormonal; Cell Division; Cell Line, Tumor; Cyclin-Dependent | 2006 |
Rapid pituitary tumor shrinkage with dissociation between antiproliferative and antisecretory effects of a long-acting octreotide in an acromegalic patient.
Topics: Acromegaly; Adenoma, Acidophil; Adult; Cabergoline; Cell Proliferation; Cells, Cultured; Delayed-Act | 2007 |
Glucocorticoids inhibit the growth of AtT-20 mouse pituitary tumor cells.
Topics: Adrenocorticotropic Hormone; Animals; Cell Division; Cell Line; Dexamethasone; DNA, Neoplasm; Glucoc | 1984 |
Dual effects of estradiol on normal and tumor pituitary cell multiplication.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Estradiol; Male; Pituitary Gland, Anterior; Pituitary | 1984 |
The D2 dopamine receptor mediates inhibition of growth in GH4ZR7 cells: involvement of protein kinase-C epsilon.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alprenolol; Animals; Apomorphine; Benzaz | 1994 |
Effects of gonadal steroids on the growth of human pituitary adenomas in vitro.
Topics: Adenoma; Adult; Androgens; Bromocriptine; Cell Division; Dihydrotestosterone; Estradiol; Female; Fol | 1995 |
Inhibition of rat pituitary tumor cell proliferation by benzodiazepines in vitro.
Topics: Animals; Benzodiazepines; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Li | 1994 |
Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells.
Topics: Actins; Adolescent; Animals; Blotting, Northern; Caprylates; Cell Cycle; Cricetinae; Culture Media, | 1993 |
Nerve growth factor suppresses the transforming phenotype of human prolactinomas.
Topics: Animals; Binding, Competitive; Bromocriptine; Cell Division; Cell Membrane; Humans; Kinetics; Mice; | 1993 |
AMP is a component of the low molecular weight mitogenic activity present in human pituitary tumours.
Topics: Adenosine Monophosphate; Animals; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liqu | 1996 |
Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells.
Topics: Adenoma; Adult; Aged; Animals; Cell Division; Cinnamates; Culture Media, Conditioned; Enzyme Inhibit | 1997 |
Progesterone receptor gene expression in craniopharyngiomas and evidence for biological activity.
Topics: Adolescent; Adult; Child; Craniopharyngioma; Estradiol; Female; Gene Expression; Humans; Male; Middl | 1997 |
Angiotensin II-induced Ca2+ mobilization and prolactin release in normal and hyperplastic pituitary cells.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; DNA Replication; Estrogens; Female; Hyperplasia; | 1998 |
Usefulness of markers of cell proliferation in the management of pituitary adenomas.
Topics: Adenoma; Antibodies, Monoclonal; Biomarkers, Tumor; Cell Cycle; Cell Division; Flow Cytometry; Human | 1998 |
Differential regulation of MAP kinase activity by corticotropin-releasing hormone in normal and neoplastic corticotropes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Depen | 1998 |
Activin effects on neoplastic proliferation of human pituitary tumors.
Topics: Activin Receptors; Activins; Adenoma; Adult; Aged; Aged, 80 and over; Blotting, Western; Cell Divisi | 2000 |
Induction of prolactin synthesis in rat pituitary tumor cells by 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Line; Clone Cells; Growth Hormone; Pituitary Neoplasms; Prolactin; | 1977 |
On the mechanism of 5-bromodeoxyuridine induction of prolactin synthesis in rat pituitary tumor cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; DNA, Neoplasm; Pituitary Neoplasms; Prolactin; Rats; Thymidin | 1979 |
Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity.
Topics: Adenylyl Cyclases; Animals; Biological Transport; DNA Replication; DNA, Neoplasm; Dopamine; Haloperi | 1992 |
Ca2+ channel modulation and kinase-C activation in a pituitary cell line: induction of immediate early genes and inhibition of proliferation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific.
Topics: Actins; Animals; Cell Division; Cell Line; DNA Replication; Estradiol; Gene Expression Regulation, N | 1992 |
The effects of chronic exposure to supraphysiological concentrations of 3, 5, 3' triiodo-L-thyronine (T3) on cultured GC cells.
Topics: Animals; Cell Division; Cell Line; Cell Survival; DNA Replication; Growth Hormone; Hot Temperature; | 1991 |
Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation.
Topics: Animals; Antineoplastic Agents; Bryostatins; Cell Adhesion; Cell Cycle; Cell Division; Cell Line; DN | 1991 |
Bromocriptine inhibits incorporation of [3H]thymidine into rat pituitary tumor cells.
Topics: Animals; Bromocriptine; Clone Cells; DNA, Neoplasm; Pituitary Neoplasms; Prolactin; Rats; Receptors, | 1986 |
The rate of appearance of thyroid hormone nuclear receptor is increased during deoxyribose nucleic acid synthesis in GC cells: analysis of thymidine-treated GC cells using dense amino acid labeling.
Topics: Animals; Cell Line; Cell Nucleus; DNA Replication; Kinetics; Pituitary Neoplasms; Rats; Receptors, T | 1986 |
Prolactin and growth hormone synthesis and thymidine incorporation in dissociated rat pituitary tumor cells.
Topics: Animals; Diethylstilbestrol; Estrogens; Female; Growth Hormone; In Vitro Techniques; Pituitary Gland | 1986 |
On the viability of tumour cells in artificially produced suspensions.
Topics: Adenine; Animals; Autoradiography; Cell Division; DNA, Neoplasm; In Vitro Techniques; Methylcholanth | 1965 |
The development of TSH producing pituitary tumours in the mouse.
Topics: Animals; Autoradiography; Cell Count; Cell Nucleus; Cilia; Endoplasmic Reticulum; Endothelium; Macro | 1973 |
Metabolic studies on mammary tumor MTW9 following resection of the mammosomatotropic tumor MtTW5.
Topics: Aminoisobutyric Acids; Animals; Carbon Isotopes; DNA, Neoplasm; Glycine; In Vitro Techniques; Mammar | 1971 |
DNA fragmentation in a clonal line of rat pituitary tumor (GH1 strain).
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Clone Cells; DNA Replication; DNA, Neoplasm; P | 1971 |
Effect of insulin on growth hormone (GH) induction by cortisol in rat pituitary tumor cells.
Topics: Animals; Cell Line; Culture Techniques; DNA; Drug Synergism; Growth Hormone; Hydrocortisone; Insulin | 1970 |
Correlation between mitotic activity and transplantability of pituitary tumors following radiothyroidectomy.
Topics: Animals; Female; Injections, Intraperitoneal; Iodine Isotopes; Male; Methods; Mice; Mitosis; Pituita | 1969 |
Effect of exogenous thyroxine on 3H-thymidine uptake in mouse pituitary gland.
Topics: Animals; Depression, Chemical; Female; Mice; Pituitary Gland; Pituitary Neoplasms; Thymidine; Thyroi | 1969 |
Cell population kinetics during the induction of thyrotropic pituitary tumors.
Topics: Animals; Cell Division; Mice; Neoplasms, Experimental; Pituitary Gland; Pituitary Neoplasms; RNA; Th | 1966 |