thymidine has been researched along with Osteosarcoma in 102 studies
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test a novel strategy for overcoming intrinsic resistance to methotrexate (MTX) in osteosarcoma (OS) due to nucleoside and nucleobase salvage (NS)." | 7.71 | Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. ( Cole, PD; Kamen, BA; Smith, AK, 2002) |
| " NET at picomolar concentrations in vitro stimulated the proliferation of human TE85 osteosarcoma cells as assessed by the increase in [3H]thymidine incorporation into DNA and in cell number and also stimulated the release of osteocalcin in both the presence and absence of 10 nM 1,25-(OH)2D3." | 7.69 | Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption. ( Baylink, DJ; Demarest, KT; Lau, KH; Linkhart, TA; Wang, SP, 1994) |
| "We recently reported that picomolar doses of norethindrone (NET), a synthetic analog of 19-nortestosterone, significantly stimulated human TE85 osteosarcoma cell proliferation, differentiation, and activity in vitro." | 7.69 | Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells. ( Baylink, DJ; Lau, KH; Takada, J, 1995) |
| "The interaction of epidermal growth factor (EGF) and PTH with UMR 106 osteosarcoma cells was examined biochemically and morphologically." | 7.68 | Biochemical and morphological analysis of the interaction of epidermal growth factor and parathyroid hormone with UMR 106 osteosarcoma cells. ( Bernier, SM; Goltzman, D; Rouleau, MF, 1991) |
| "High-dose methotrexate (MTX) therapy with subsequent leucovorin (LV) rescue (HDMTX-LV) in the treatment of osteosarcoma is based on the assumption that this tumor has a deficient uptake system for MTX and reduced folates." | 7.67 | High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines. ( Diddens, H; Niethammer, D; Teufel, T, 1987) |
| "Hypoxanthine:guanine phosphoribosyltransferase (HPRT) activity was measured in 14 human osteosarcomas to test whether a subset of these tumors was deficient in the purine salvage pathway enzyme and thus provide a rationale for therapy with methotrexate-thymidine rescue." | 7.67 | Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue? ( Houghton, JA; Houghton, PJ; Meyer, WH, 1987) |
| "5 mM concentration inhibited [3H]thymidine uptake by C3H/He mouse osteosarcoma (OS) cells, while L-arginine, L-phenylalanine, and glycine had little effect on the uptake." | 7.66 | Inhibitory effect of L-homoarginine on murine osteosarcoma cell proliferation. ( Ghanta, VK; Hiramoto, RN; Kikuchi, Y; Parmley, RT; Takagi, M, 1982) |
| "Many clinical studies have been conducted on the role of high-dose methotrexate (MTX) in human osteosarcoma, but information about the in vitro effect of MTX on human osteosarcoma cells is lacking." | 7.66 | Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate. ( Chacón, RD; Filmus, J; Mordoh, J, 1981) |
| " The cells were grown in antibiotic-free media and exposed to concentrations of ciprofloxacin at 0, 10, 100, 200, and 1,000 microg/ml to establish an initial dose-response curve." | 5.30 | Effect of ciprofloxacin on the proliferation of osteoblast-like MG-63 human osteosarcoma cells in vitro. ( Dahners, LE; Edin, ML; Lester, GE; Lindsey, RW; Miclau, T, 1998) |
| "Transforming growth factor beta was shown to be a biphasic stimulator of [3H]thymidine uptake in HOS TE85, with maximal stimulation occurring at 0." | 5.29 | Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta. ( Antich, PP; Pak, CY; Reed, BY; Zerwekh, JE, 1993) |
| "To test a novel strategy for overcoming intrinsic resistance to methotrexate (MTX) in osteosarcoma (OS) due to nucleoside and nucleobase salvage (NS)." | 3.71 | Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. ( Cole, PD; Kamen, BA; Smith, AK, 2002) |
| " A thymidine kinase-deficient osteosarcoma cell line was transduced with the recombinant virus and we compared the sensitivity and bystander cell killing when the cell lines were incubated with the pyrimidine nucleoside analogs (E)-5-(2-bromovinyl)-2'-deoxyuridine and 1-beta-D-arabinofuranosylthymine." | 3.71 | Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol. ( Johansson, M; Karlsson, A; Zheng, X, 2001) |
| " Proliferation (cell number and [3H]-thymidine incorporation), differentiation (alkaline phosphatase and osteocalcin), matrix synthesis ([35S]-sulfate incorporation; percentage of collagen production), and local factor production (prostaglandin E2 [PGE2] and transforming growth factor-beta 1 [TGF-beta1]) were measured in cultures of 2T9 cells (pre-osteoblasts which exhibit osteogenesis in response to bone morphogenetic protein-2 [BMP-2]), MG63 human osteoblast-like osteosarcoma cells, and normal human osteoblasts (NHOst cells)." | 3.70 | Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of ( Boyan, BD; Carnes, DL; Cochran, DL; Dean, DD; Liu, Y; Lohmann, CH; Pulliam, R; Schwartz, Z; Sylvia, VL, 2000) |
| " The human pancreatic adenocarcinoma cell line MIA PaCa-2 and a thymidine kinase-deficient osteosarcoma cell line were transduced with the recombinant virus." | 3.70 | Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. ( Johansson, M; Karlsson, A; Zheng, X, 2000) |
| " NET at picomolar concentrations in vitro stimulated the proliferation of human TE85 osteosarcoma cells as assessed by the increase in [3H]thymidine incorporation into DNA and in cell number and also stimulated the release of osteocalcin in both the presence and absence of 10 nM 1,25-(OH)2D3." | 3.69 | Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption. ( Baylink, DJ; Demarest, KT; Lau, KH; Linkhart, TA; Wang, SP, 1994) |
| "[3H]Thymidine (TdR) incorporation by human osteosarcoma cell line MG-63 was significantly stimulated at as early as 3 h after the addition of either TIMP-1 or TIMP-2 alone." | 3.69 | Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2). ( Hamaguchi, M; Hayakawa, T; Iwata, H; Koike, T; Noguchi, T; Shinagawa, A; Suzuki, M; Yamashita, K, 1996) |
| "We recently reported that picomolar doses of norethindrone (NET), a synthetic analog of 19-nortestosterone, significantly stimulated human TE85 osteosarcoma cell proliferation, differentiation, and activity in vitro." | 3.69 | Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells. ( Baylink, DJ; Lau, KH; Takada, J, 1995) |
| " The present study sought to test if dexamethasone (Dex) could potentiate the action of fluoride to increase the detectability of the stimulatory effects of fluoride on [3H]thymidine incorporation, alkaline phosphatase (ALP) specific activity, collagen synthesis, and osteocalcin secretion in human TE85 osteosarcoma cells." | 3.69 | Dexamethasone enhances the osteogenic effects of fluoride in human TE85 osteosarcoma cells in vitro. ( Baylink, DJ; Chevalley, T; Lau, KH; Takada, J, 1996) |
| "The present study was performed to investigate the regulation of cytosolic pH (pHi) and DNA synthesis by parathyroid hormone(PTH) and PTH-related peptide (PTHrP) in osteoblasts, using osteoblastic osteosarcoma cells, UMR-106 which possessed PTH-responsive dual signal transduction systems (cAMP-dependent protein kinase (PKA) and calcium/protein kinase C [Ca/PKC]) and amiloride-inhibitable Na+/H+ exchange system." | 3.68 | Second messenger signaling in the regulation of cytosolic pH and DNA synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells: role of Na+/H+ exchange. ( Fujita, T; Fukase, M; Kano, J; Sugimoto, T, 1992) |
| "After high dose methotrexate (CAS 59-05-2) therapy of children with non-metastatic osteosarcoma the activity of an alkaline DNase with substrate specificity for denaturated DNA increases in lymphocytes and PHA-stimulated lymphocytes." | 3.68 | Increasing alkaline DNase activity with substrate specificity for denaturated DNA after high dose methotrexate therapy. ( Gutjahr, P; Reitz, M, 1991) |
| "The interaction of epidermal growth factor (EGF) and PTH with UMR 106 osteosarcoma cells was examined biochemically and morphologically." | 3.68 | Biochemical and morphological analysis of the interaction of epidermal growth factor and parathyroid hormone with UMR 106 osteosarcoma cells. ( Bernier, SM; Goltzman, D; Rouleau, MF, 1991) |
| "8 rat osteogenic osteosarcoma cells, and other bone-derived cells in culture, as well as sex-specific stimulation of diaphyseal bone in vivo by estrogen and testosterone, using [3H]thymidine incorporation into DNA and stimulation of the specific activity of creatine kinase as markers." | 3.68 | Hormonal stimulation of bone cell proliferation. ( Harell, A; Kaye, AM; Sömjen, D; Weisman, Y, 1990) |
| "Uptake of H-3 thymidine was studied in mice, both normal and with spontaneous lymphoma, and in the organs and tumors of dogs with spontaneous tumors." | 3.67 | Short-term thymidine uptake in normal and neoplastic tissues: studies for PET. ( Graham, MM; Grunbaum, Z; Larson, SM; Shields, AF, 1984) |
| "Aluminum-induced osteomalacia is a frequent complication observed in patients on maintenance hemodialysis." | 3.67 | Micromolar aluminum levels reduce 3H-thymidine incorporation by cell line UMR 106-01. ( Avioli, R; Blair, HC; Crouch, EC; Finch, JL; Slatopolsky, E; Teitelbaum, SL, 1989) |
| "Hypoxanthine:guanine phosphoribosyltransferase (HPRT) activity was measured in 14 human osteosarcomas to test whether a subset of these tumors was deficient in the purine salvage pathway enzyme and thus provide a rationale for therapy with methotrexate-thymidine rescue." | 3.67 | Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue? ( Houghton, JA; Houghton, PJ; Meyer, WH, 1987) |
| "High-dose methotrexate (MTX) therapy with subsequent leucovorin (LV) rescue (HDMTX-LV) in the treatment of osteosarcoma is based on the assumption that this tumor has a deficient uptake system for MTX and reduced folates." | 3.67 | High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines. ( Diddens, H; Niethammer, D; Teufel, T, 1987) |
| "5 mM concentration inhibited [3H]thymidine uptake by C3H/He mouse osteosarcoma (OS) cells, while L-arginine, L-phenylalanine, and glycine had little effect on the uptake." | 3.66 | Inhibitory effect of L-homoarginine on murine osteosarcoma cell proliferation. ( Ghanta, VK; Hiramoto, RN; Kikuchi, Y; Parmley, RT; Takagi, M, 1982) |
| "Many clinical studies have been conducted on the role of high-dose methotrexate (MTX) in human osteosarcoma, but information about the in vitro effect of MTX on human osteosarcoma cells is lacking." | 3.66 | Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate. ( Chacón, RD; Filmus, J; Mordoh, J, 1981) |
| "Proliferation kinetic parameters of 9 osteogenic sarcomas (6 primary tumours, 3 lung metastases) and 3 Ewing's sarcomas were determined using an autoradiographic in vitro method (single and double labelling with 3H- and 14C-thymidine, and 3H-uridine)." | 3.66 | Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children. ( Willnow, U, 1982) |
| " Results show that the cell proliferation rate of the stem cells in respective tissues was markedly suppressed, dependent on time after dosing and the dose of 90Y; 3." | 1.32 | Synchronous evaluation of toxico- and pharmaco-dynamics of yttrium-90 by a novel autoradiographic procedure. ( Awazu, S; Debori, Y; Hamai, Y; Hatori, A; Higashi, N; Kawai, N; Kuroiwa, H; Sato, Y; Shigematsu, A; Takeuchi, N; Yamabayashi, H; Yamamoto, T; Yui, J, 2004) |
| "[3H]Thymidine incorporation was used to evaluate cell proliferation." | 1.30 | Correlation between pulsed electromagnetic fields exposure time and cell proliferation increase in human osteosarcoma cell lines and human normal osteoblast cells in vitro. ( Baroni, T; Caruso, A; De Mattei, M; Pezzetti, F; Sollazzo, V; Traina, GC, 1999) |
| " The cells were grown in antibiotic-free media and exposed to concentrations of ciprofloxacin at 0, 10, 100, 200, and 1,000 microg/ml to establish an initial dose-response curve." | 1.30 | Effect of ciprofloxacin on the proliferation of osteoblast-like MG-63 human osteosarcoma cells in vitro. ( Dahners, LE; Edin, ML; Lester, GE; Lindsey, RW; Miclau, T, 1998) |
| " As the phosphate concentration was increased, the biphasic fluoride dose-response curve was shifted to a lower range of fluoride concentrations." | 1.29 | Fluoride increases net 45Ca uptake by SaOS-2 cells: The effect is phosphate dependent. ( Farley, JR; Hall, SL; Herring, S; Tanner, MA, 1993) |
| "Transforming growth factor beta was shown to be a biphasic stimulator of [3H]thymidine uptake in HOS TE85, with maximal stimulation occurring at 0." | 1.29 | Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta. ( Antich, PP; Pak, CY; Reed, BY; Zerwekh, JE, 1993) |
| " TF produced a shift to the left in the inhibitory dose-response curve to Al in osteoblast-like cells; thus, DNA synthesis decreased at substantially lower media concentrations of Al in cells grown in SFM containing partially saturated Al-TF." | 1.28 | Transferrin enhances the antiproliferative effect of aluminum on osteoblast-like cells. ( Goodman, WG; Hori, MT; Kasai, K, 1991) |
| "The rat osteogenic sarcoma subclone UMR-106-01 is a cell type with osteoblast-like properties." | 1.28 | Insulin promotes growth of the cultured rat osteosarcoma cell line UMR-106-01: an osteoblast-like cell. ( Hickman, J; McElduff, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (42.16) | 18.7374 |
| 1990's | 37 (36.27) | 18.2507 |
| 2000's | 19 (18.63) | 29.6817 |
| 2010's | 3 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bradshaw, TJ | 1 |
| Bowen, SR | 1 |
| Deveau, MA | 1 |
| Kubicek, L | 1 |
| White, P | 1 |
| Bentzen, SM | 1 |
| Chappell, RJ | 1 |
| Forrest, LJ | 1 |
| Jeraj, R | 1 |
| Johnson, M | 1 |
| Sharma, M | 1 |
| Brocardo, MG | 1 |
| Henderson, BR | 1 |
| Wiebe, LI | 1 |
| Sun, W | 1 |
| Zhou, A | 1 |
| Yang, J | 1 |
| Sjuvarsson, EV | 1 |
| Eriksson, S | 1 |
| Paproski, RJ | 1 |
| Cass, CE | 1 |
| Kumar, P | 1 |
| Knaus, EE | 1 |
| Cole, PD | 1 |
| Smith, AK | 1 |
| Kamen, BA | 1 |
| Cohly, HH | 1 |
| Abraham, GE | 1 |
| Ndebele, K | 1 |
| Jenkins, JJ | 1 |
| Thompson, J | 1 |
| Angel, MF | 1 |
| Zheng, X | 3 |
| Lundberg, M | 1 |
| Karlsson, A | 3 |
| Johansson, M | 3 |
| Conover, CA | 1 |
| Khosla, S | 1 |
| Schelling, P | 1 |
| Claus, MT | 1 |
| Johner, R | 1 |
| Marquez, VE | 1 |
| Schulz, GE | 1 |
| Scapozza, L | 1 |
| Agapova, LS | 1 |
| Volodina, JL | 1 |
| Chumakov, PM | 1 |
| Kopnin, BP | 1 |
| Stains, JP | 1 |
| Lecanda, F | 1 |
| Towler, DA | 1 |
| Civitelli, R | 1 |
| Chipoy, C | 1 |
| Berreur, M | 1 |
| Couillaud, S | 1 |
| Pradal, G | 1 |
| Vallette, F | 1 |
| Colombeix, C | 1 |
| Rédini, F | 1 |
| Heymann, D | 1 |
| Blanchard, F | 1 |
| Shigematsu, A | 1 |
| Kawai, N | 1 |
| Kuroiwa, H | 1 |
| Higashi, N | 1 |
| Debori, Y | 1 |
| Yui, J | 1 |
| Hamai, Y | 1 |
| Hatori, A | 1 |
| Awazu, S | 1 |
| Takeuchi, N | 1 |
| Yamabayashi, H | 1 |
| Sato, Y | 1 |
| Yamamoto, T | 1 |
| Lafleur, EA | 1 |
| Koshkina, NV | 1 |
| Stewart, J | 1 |
| Jia, SF | 1 |
| Worth, LL | 1 |
| Duan, X | 1 |
| Kleinerman, ES | 1 |
| Sakayama, K | 1 |
| Mashima, N | 1 |
| Kidani, T | 1 |
| Miyazaki, T | 1 |
| Yamamoto, H | 1 |
| Masuno, H | 1 |
| Scarlett, A | 1 |
| Parsons, MP | 1 |
| Hanson, PL | 1 |
| Sidhu, KK | 1 |
| Milligan, TP | 1 |
| Burrin, JM | 1 |
| Kikuchi, Y | 1 |
| Takagi, M | 1 |
| Parmley, RT | 1 |
| Ghanta, VK | 1 |
| Hiramoto, RN | 1 |
| Umeda, T | 1 |
| Matsuoka, O | 1 |
| Ng, KW | 1 |
| Partridge, NC | 1 |
| Niall, M | 1 |
| Martin, TJ | 1 |
| Acker, H | 1 |
| Holtermann, G | 1 |
| Carlsson, J | 1 |
| Nederman, T | 1 |
| Ichino, Y | 1 |
| Ishikawa, T | 1 |
| Shields, AF | 1 |
| Larson, SM | 1 |
| Grunbaum, Z | 1 |
| Graham, MM | 1 |
| Eilam, Y | 1 |
| Silbermann, M | 2 |
| Szydel, N | 1 |
| Mordoh, J | 1 |
| Chacón, RD | 1 |
| Filmus, J | 1 |
| Willnow, U | 2 |
| Pinski, J | 1 |
| Schally, AV | 1 |
| Groot, K | 1 |
| Halmos, G | 1 |
| Szepeshazi, K | 1 |
| Zarandi, M | 1 |
| Armatis, P | 1 |
| Sömjen, D | 2 |
| Weisman, Y | 2 |
| Kaye, AM | 2 |
| Kasperk, C | 1 |
| Wergedal, J | 2 |
| Strong, D | 1 |
| Farley, J | 2 |
| Wangerin, K | 1 |
| Gropp, H | 1 |
| Ziegler, R | 1 |
| Baylink, DJ | 5 |
| Andress, DL | 1 |
| Loop, SM | 1 |
| Zapf, J | 1 |
| Kiefer, MC | 1 |
| Lau, KH | 5 |
| Wang, SP | 2 |
| Linkhart, TA | 1 |
| Demarest, KT | 1 |
| Genty, C | 1 |
| Palle, S | 1 |
| Vanelle, L | 1 |
| Bourrin, S | 1 |
| Alexandre, C | 1 |
| Zhou, Y | 1 |
| Li, J | 1 |
| Xu, K | 1 |
| Hu, SX | 1 |
| Benedict, WF | 1 |
| Xu, HJ | 1 |
| Raile, K | 1 |
| Höflich, A | 1 |
| Kessler, U | 1 |
| Yang, Y | 1 |
| Pfuender, M | 1 |
| Blum, WF | 1 |
| Kolb, H | 1 |
| Schwarz, HP | 1 |
| Kiess, W | 1 |
| Farley, JR | 2 |
| Hall, SL | 2 |
| Herring, S | 2 |
| Tanner, MA | 1 |
| Norman, AW | 1 |
| Bouillon, R | 1 |
| Farach-Carson, MC | 1 |
| Bishop, JE | 1 |
| Zhou, LX | 1 |
| Nemere, I | 1 |
| Zhao, J | 1 |
| Muralidharan, KR | 1 |
| Okamura, WH | 1 |
| Reed, BY | 1 |
| Zerwekh, JE | 1 |
| Antich, PP | 1 |
| Pak, CY | 1 |
| Carbonaro-Hall, D | 2 |
| Williams, R | 2 |
| Wu, L | 1 |
| Warburton, D | 2 |
| Zeichner-David, M | 1 |
| MacDougall, M | 1 |
| Tolo, V | 1 |
| Hall, F | 1 |
| Downes, S | 1 |
| Clifford, CJ | 1 |
| Scotchford, C | 1 |
| Klein, CP | 1 |
| Hall, FL | 1 |
| Benya, PD | 1 |
| Padilla, SR | 1 |
| Buckley, S | 1 |
| Takada, J | 2 |
| Chevalley, T | 1 |
| Glantschnig, H | 1 |
| Varga, F | 1 |
| Klaushofer, K | 1 |
| Yamashita, K | 1 |
| Suzuki, M | 1 |
| Iwata, H | 1 |
| Koike, T | 1 |
| Hamaguchi, M | 1 |
| Shinagawa, A | 1 |
| Noguchi, T | 1 |
| Hayakawa, T | 1 |
| Rao, LG | 1 |
| Sutherland, MK | 1 |
| Reddy, GS | 1 |
| Siu-Caldera, ML | 1 |
| Uskokovic, MR | 1 |
| Murray, TM | 1 |
| Haberkorn, U | 1 |
| Oberdorfer, F | 1 |
| Klenner, T | 1 |
| Strauss, LG | 1 |
| Stöhr, M | 1 |
| Wallich, R | 1 |
| Altmann, A | 1 |
| Kaick, GV | 1 |
| Kenny, JS | 1 |
| Kisaalita, WS | 1 |
| Rowland, G | 1 |
| Thai, C | 1 |
| Foutz, T | 1 |
| Terada, M | 1 |
| Inaba, M | 1 |
| Yano, Y | 1 |
| Hasuma, T | 1 |
| Nishizawa, Y | 1 |
| Morii, H | 1 |
| Otani, S | 1 |
| Miclau, T | 1 |
| Edin, ML | 1 |
| Lester, GE | 1 |
| Lindsey, RW | 1 |
| Dahners, LE | 1 |
| De Mattei, M | 1 |
| Caruso, A | 1 |
| Traina, GC | 1 |
| Pezzetti, F | 1 |
| Baroni, T | 1 |
| Sollazzo, V | 1 |
| Dean, DD | 2 |
| Schwartz, Z | 2 |
| Liu, Y | 2 |
| Blanchard, CR | 1 |
| Agrawal, CM | 1 |
| Mabrey, JD | 1 |
| Sylvia, VL | 2 |
| Lohmann, CH | 2 |
| Boyan, BD | 2 |
| Zaman, G | 1 |
| Cheng, MZ | 1 |
| Jessop, HL | 1 |
| White, R | 1 |
| Lanyon, LE | 1 |
| Adkisson, HD | 1 |
| Strauss-Schoenberger, J | 1 |
| Gillis, M | 1 |
| Wilkins, R | 1 |
| Jackson, M | 1 |
| Hruska, KA | 1 |
| Dimai, HP | 1 |
| Stilt-Coffing, B | 1 |
| Farley, P | 1 |
| Pham, T | 1 |
| Mohan, S | 2 |
| Carnes, DL | 1 |
| Pulliam, R | 1 |
| Cochran, DL | 1 |
| Hashimoto, H | 1 |
| Kofránek, V | 1 |
| Parízek, O | 1 |
| Svoboda, V | 1 |
| Bubeníková, D | 1 |
| Machek, J | 1 |
| Glasgow, LA | 1 |
| Crane, JL | 1 |
| Kern, ER | 1 |
| Chang, YC | 1 |
| Yao, CS | 1 |
| Bertino, JR | 1 |
| Johnson, AH | 1 |
| Collins, PB | 1 |
| Sauer, H | 1 |
| Schalhorn, A | 1 |
| Wilmanns, W | 1 |
| Frei, E | 2 |
| Winters, WD | 1 |
| Boddie, AW | 1 |
| Roth, JA | 1 |
| Adams, JM | 1 |
| Ferguson, RJ | 1 |
| McMaster, JH | 2 |
| Weinert, CR | 1 |
| Jaffe, N | 1 |
| Tattersall, MH | 1 |
| Pitman, S | 1 |
| Parker, L | 1 |
| Liel, Y | 1 |
| Kraus, S | 1 |
| Levy, J | 1 |
| Shany, S | 1 |
| Sugimoto, T | 2 |
| Kano, J | 2 |
| Fukase, M | 2 |
| Fujita, T | 2 |
| Rabbani, SA | 2 |
| Mazar, AP | 1 |
| Bernier, SM | 2 |
| Haq, M | 1 |
| Bolivar, I | 1 |
| Henkin, J | 1 |
| Goltzman, D | 3 |
| Fang, MA | 1 |
| Kujubu, DA | 1 |
| Hahn, TJ | 1 |
| Tarbaux, NM | 1 |
| Matsuyama, T | 1 |
| Wergedal, JE | 1 |
| Yoo, A | 1 |
| Reitz, M | 1 |
| Gutjahr, P | 1 |
| Kasai, K | 1 |
| Hori, MT | 1 |
| Goodman, WG | 1 |
| Rouleau, MF | 1 |
| Harell, A | 1 |
| Koutsilieris, M | 1 |
| Bautista, CM | 1 |
| Hickman, J | 1 |
| McElduff, A | 1 |
| Blair, HC | 1 |
| Finch, JL | 1 |
| Avioli, R | 1 |
| Crouch, EC | 1 |
| Slatopolsky, E | 1 |
| Teitelbaum, SL | 1 |
| Schmidt, J | 1 |
| Closs, EI | 1 |
| Livne, E | 1 |
| Erfle, V | 1 |
| Weir, EC | 1 |
| Insogna, KL | 1 |
| Horowitz, MC | 1 |
| Birek, C | 1 |
| Pawson, T | 1 |
| McCulloch, CA | 1 |
| Tenenbaum, HC | 1 |
| Meyer, WH | 1 |
| Houghton, JA | 1 |
| Houghton, PJ | 1 |
| Bell, RS | 1 |
| Bourret, LA | 1 |
| Bell, DF | 1 |
| Gebhardt, MC | 1 |
| Rosenberg, A | 1 |
| Berrey, HB | 1 |
| Treadwell, BV | 1 |
| Tomford, WW | 1 |
| Mankin, HJ | 1 |
| Lelieveld, P | 1 |
| Mulder, JH | 1 |
| Diddens, H | 1 |
| Teufel, T | 1 |
| Niethammer, D | 1 |
| Thurston, MN | 1 |
| Kember, NF | 1 |
| Oreffo, RO | 1 |
| Francis, JA | 1 |
| Triffitt, JT | 1 |
| Jose, DG | 1 |
| Seshadri, R | 1 |
| Norrby, K | 1 |
| Mellgren, J | 1 |
| Anderson, RJ | 1 |
| McBride, CM | 2 |
| Hersh, EM | 2 |
| Janik, P | 1 |
| Steel, GG | 1 |
| MacPherson, BR | 1 |
| Pilch, YH | 1 |
| Mavligit, GM | 1 |
| Ambus, U | 1 |
| Gutterman, JU | 1 |
| Han, T | 1 |
| Scranton, PE | 1 |
| Mayhew, E | 1 |
| Schwartz, HS | 1 |
| Sodergren, JE | 1 |
| Mamabe, S | 1 |
| Takase, B | 1 |
| Yamazaki, Y | 1 |
| Akazaki, T | 1 |
| Shima, I | 1 |
1 review available for thymidine and Osteosarcoma
| Article | Year |
|---|---|
Methotrexate revisited.
Topics: Adolescent; Adult; Alkalies; Aminopterin; Animals; Bone Marrow; Bone Neoplasms; Drug Therapy, Combin | 1976 |
101 other studies available for thymidine and Osteosarcoma
| Article | Year |
|---|---|
Molecular imaging biomarkers of resistance to radiation therapy for spontaneous nasal tumors in canines.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Chondrosarcoma; Coordination Complexes; Dog Disea | 2015 |
IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line, Tumor; Cell Nucleus; Cytoplasm; DNA Replication; | 2011 |
Biochemistry and biology of 2'-Fluoro-2'-deoxythymidine (FT), a putative highly selective substrate for thymidine kinase type 2 (TK2).
Topics: Animals; Antineoplastic Agents; Autoradiography; Bone Neoplasms; Cell Line, Tumor; Dose-Response Rel | 2012 |
Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Bone Neoplasms; Cattle; Culture Medi | 2002 |
Effects of static electromagnetic fields on characteristics of MG-63 osteoblasts grown in culture.
Topics: Bone Neoplasms; Cell Division; Electromagnetic Fields; Gene Expression Regulation, Neoplastic; Human | 2003 |
Lipid-mediated protein delivery of suicide nucleoside kinases.
Topics: Animals; Arabinonucleosides; Bone Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; CHO Cells; Criceti | 2003 |
Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts.
Topics: Animals; Apoptosis; Bone Neoplasms; Breast Neoplasms; Cattle; Cell Division; Cells, Cultured; Collag | 2003 |
Biochemical and structural characterization of (South)-methanocarbathymidine that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cells.
Topics: Antiviral Agents; Binding Sites; Cell Division; Cell Line, Tumor; Crystallography, X-Ray; Dose-Respo | 2004 |
Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint.
Topics: Blotting, Western; CDC2 Protein Kinase; Cell Line, Tumor; Cell Separation; Cyclin B; Cyclin B1; DNA; | 2004 |
Heterogeneous nuclear ribonucleoprotein K represses transcription from a cytosine/thymidine-rich element in the osteocalcin promoter.
Topics: Animals; Base Composition; Base Sequence; Cell Line, Tumor; Cytosine; DNA; DNA, Single-Stranded; Het | 2005 |
Downregulation of osteoblast markers and induction of the glial fibrillary acidic protein by oncostatin M in osteosarcoma cells require PKCdelta and STAT3.
Topics: Alkaline Phosphatase; Animals; Anthraquinones; Blotting, Western; Bone and Bones; Bone Marrow Cells; | 2004 |
Synchronous evaluation of toxico- and pharmaco-dynamics of yttrium-90 by a novel autoradiographic procedure.
Topics: Animals; Area Under Curve; Autoradiography; Bone Marrow; Bone Neoplasms; Cell Line, Tumor; Cell Nucl | 2004 |
Increased Fas expression reduces the metastatic potential of human osteosarcoma cells.
Topics: Animals; Apoptosis; Bone Neoplasms; fas Receptor; Gene Expression Regulation, Neoplastic; Humans; Lu | 2004 |
Effect of cortisol on cell proliferation and the expression of lipoprotein lipase and vascular endothelial growth factor in a human osteosarcoma cell line.
Topics: Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Replication; Hormone An | 2008 |
Thyroid hormone stimulation of extracellular signal-regulated kinase and cell proliferation in human osteoblast-like cells is initiated at integrin alphaVbeta3.
Topics: Cell Division; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expre | 2008 |
Inhibitory effect of L-homoarginine on murine osteosarcoma cell proliferation.
Topics: Alkaline Phosphatase; Animals; Arginine; Cell Division; Cells, Cultured; Depression, Chemical; Femal | 1982 |
[Double tracer autoradiography of bone tumor using 3H-thymidine and radionuclides for diagnostic purpose].
Topics: Animals; Autoradiography; Bone Neoplasms; Diphosphonates; Gallium Radioisotopes; Half-Life; Male; Mi | 1982 |
Epidermal growth factor receptors in clonal lines of a rat osteogenic sarcoma and in osteoblast-rich rat bone cells.
Topics: Animals; Cell Line; Cells, Cultured; Clone Cells; ErbB Receptors; Iodine Radioisotopes; Osteoblasts; | 1983 |
Methodological aspects of microelectrode measurements in cellular spheroids.
Topics: Animals; Autoradiography; Cell Aggregation; Cells, Cultured; Cricetinae; Culture Media; Glioma; Huma | 1983 |
Cytolysis of autologous fresh osteosarcoma cells by human cytotoxic T lymphocytes propagated with T cell growth factor.
Topics: Adolescent; Cell Membrane; Cells, Cultured; Cytotoxicity, Immunologic; Female; Humans; Interleukin-2 | 1983 |
Short-term thymidine uptake in normal and neoplastic tissues: studies for PET.
Topics: Animals; Dogs; Lymphoma; Mice; Neoplasms; Osteosarcoma; Regional Blood Flow; Thymidine; Tissue Distr | 1984 |
Growth inhibition of clonal osteosarcoma cell-lines by low concentrations of glucocorticoid hormones.
Topics: Animals; Calcium; Cell Division; Cell Line; Clone Cells; Corticosterone; Dexamethasone; DNA, Neoplas | 1980 |
Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate.
Topics: Cell Separation; Cells, Cultured; Deoxyuridine; DNA; Drug Resistance; Humans; Hypoxanthines; Lung Ne | 1981 |
Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children.
Topics: Autoradiography; Child; Culture Techniques; Humans; Kinetics; Neoplasm Metastasis; Osteosarcoma; Sar | 1982 |
Inhibition of growth of human osteosarcomas by antagonists of growth hormone-releasing hormone.
Topics: Animals; Cyclic AMP; Growth Hormone-Releasing Hormone; Hormone Antagonists; Humans; Insulin-Like Gro | 1995 |
Pretreatment with 1,25(OH)2 vitamin D or 24,25(OH)2 vitamin D increases synergistically responsiveness to sex steroids in skeletal-derived cells.
Topics: 24,25-Dihydroxyvitamin D 3; Animals; Calcitriol; Cell Division; Cell Line; Cells, Cultured; Creatine | 1995 |
Human bone cell phenotypes differ depending on their skeletal site of origin.
Topics: Alkaline Phosphatase; Blotting, Northern; Bone and Bones; Cell Division; Cell Line; Cells, Cultured; | 1995 |
Carboxy-truncated insulin-like growth factor binding protein-5 stimulates mitogenesis in osteoblast-like cells.
Topics: Animals; Animals, Newborn; Base Sequence; Bone and Bones; Carrier Proteins; Cell Division; Cells, Cu | 1993 |
Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption.
Topics: Animals; Bone and Bones; Bone Development; Bone Resorption; Calcitriol; Cell Differentiation; Cell D | 1994 |
Colorimetric evaluation of cultured osteoblast-like cells (ROS 17/2.8).
Topics: Animals; Cell Count; Colorimetry; DNA, Neoplasm; Evaluation Studies as Topic; Methylene Blue; Micros | 1994 |
Further characterization of retinoblastoma gene-mediated cell growth and tumor suppression in human cancer cells.
Topics: Animals; Base Sequence; Bone Neoplasms; Cell Division; Cell Line; DNA Primers; DNA, Neoplasm; Gene E | 1994 |
Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I receptor
Topics: Animals; Binding, Competitive; Blood; Blotting, Northern; Blotting, Western; Bone Neoplasms; Cell Di | 1994 |
Fluoride increases net 45Ca uptake by SaOS-2 cells: The effect is phosphate dependent.
Topics: Alkaline Phosphatase; Calcium; DNA; Dose-Response Relationship, Drug; Fluorides; Humans; Osteoblasts | 1993 |
Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.
Topics: Animals; Bone and Bones; Calcitriol; Calcium; Cell Division; Cell Nucleus; Cells, Cultured; Chickens | 1993 |
Fluoride-stimulated [3H]thymidine uptake in a human osteoblastic osteosarcoma cell line is dependent on transforming growth factor beta.
Topics: Antibodies; Blotting, Northern; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Hu | 1993 |
G1 expression and multistage dynamics of cyclin A in human osteosarcoma cells.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Blotting, Northern; CDC2 Protein Kinase; Cell Cycle; Ce | 1993 |
Comparison of the release of growth hormone from hydroxyapatite, heat-treated hydroxyapatite, and fluoroapatite coatings on titanium.
Topics: Apatites; Biocompatible Materials; Bone Neoplasms; Cell Division; Ceramics; DNA; Durapatite; Enzyme- | 1995 |
Transforming growth factor-beta type-II receptor signalling: intrinsic/associated casein kinase activity, receptor interactions and functional effects of blocking antibodies.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Cartilage, Articular; Casein Kinases | 1996 |
Dexamethasone enhances the osteogenic effects of fluoride in human TE85 osteosarcoma cells in vitro.
Topics: Alkaline Phosphatase; beta-Cyclodextrins; Calcitriol; Cell Division; Collagen; Cyclodextrins; Dexame | 1996 |
Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells.
Topics: Alkaline Phosphatase; Androgens; Bone Neoplasms; Calcitriol; Collagen; Dose-Response Relationship, D | 1995 |
The cellular protooncogenes c-fos and egr-1 are regulated by prostacyclin in rodent osteoblasts and fibroblasts.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Cell Line; Cell Nucleus; DNA-Binding Proteins; Early Growth Re | 1996 |
Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2).
Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; DNA; Enzyme Activation; Genistein; Glyc | 1996 |
Effects of 1alpha,25-dihydroxy-16ene, 23yne-vitamin D3 on osteoblastic function in human osteosarcoma SaOS-2 cells: differentiation-stage dependence and modulation by 17-beta estradiol.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Calcitriol; Cell Differentiation; Dihydroxycholecalciferols | 1996 |
Metabolic and transcriptional changes in osteosarcoma cells treated with chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Deoxyglucose; Flow Cytometry; Fluorodeoxy | 1994 |
Quantitative study of calcium uptake by tumorigenic bone (TE-85) and neuroblastoma x glioma (NG108-15) cells exposed to extremely-low-frequency (ELF) electric fields.
Topics: Animals; Biological Transport; Bone Neoplasms; Calcium; Cattle; Cell Division; DNA, Neoplasm; Electr | 1997 |
Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells.
Topics: Acetyltransferases; Blotting, Northern; Blotting, Western; Cell Division; Dose-Response Relationship | 1998 |
Effect of ciprofloxacin on the proliferation of osteoblast-like MG-63 human osteosarcoma cells in vitro.
Topics: Anti-Infective Agents; Cell Count; Cell Division; Ciprofloxacin; DNA Replication; Dose-Response Rela | 1998 |
Correlation between pulsed electromagnetic fields exposure time and cell proliferation increase in human osteosarcoma cell lines and human normal osteoblast cells in vitro.
Topics: Adult; Bone Neoplasms; Cell Division; Cells, Cultured; Culture Media; Electromagnetic Fields; Humans | 1999 |
The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitro.
Topics: Adult; Alkaline Phosphatase; Cell Division; Collagen; Culture Media, Conditioned; Female; Hip Prosth | 1999 |
Mechanical strain activates estrogen response elements in bone cells.
Topics: Animals; Cell Division; Choline O-Acetyltransferase; Estradiol; Estrogen Antagonists; Fulvestrant; G | 2000 |
Rapid quantitative bioassay of osteoinduction.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Biological Assay; Bone Development; Bone Matrix; Calc | 2000 |
Calcitonin increases the concentration of insulin-like growth factors in serum-free cultures of human osteoblast-line cells.
Topics: Alkaline Phosphatase; Calcitonin; Calcium; Culture Media, Serum-Free; DNA; Dose-Response Relationshi | 2000 |
Porcine fetal enamel matrix derivative stimulates proliferation but not differentiation of pre-osteoblastic 2T9 cells, inhibits proliferation and stimulates differentiation of osteoblast-like MG63 cells, and increases proliferation and differentiation of
Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Count | 2000 |
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; A | 2000 |
Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol.
Topics: Amino Acid Sequence; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Death; Cell Nucleus; Cytos | 2001 |
Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Bone Neoplasms; Cell Division; Cholera Toxin; Fluorides; H | 2001 |
3H-TDR labelling of osteoprogenitor cells after 226RA incorporation in mice.
Topics: Animals; Autoradiography; Bone and Bones; Bone Neoplasms; Cell Division; DNA; Dose-Response Relation | 1977 |
Antitumor activity of interferon against murine osteogenic sarcoma cells in vitro.
Topics: Animals; Antibodies; Cell Division; Cells, Cultured; Interferons; Osteosarcoma; Sarcoma, Experimenta | 1978 |
Investigation of the human macrophage. II. The in vitro cytotoxicity of macrophages.
Topics: Animals; Cattle; Cell Adhesion; Cell-Free System; Cytotoxicity, Immunologic; Esophageal Neoplasms; G | 1979 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
The effects of sera from cancer patients on phytohaemagglutinin-induced lymphocyte transformation [proceedings].
Topics: Adult; Cells, Cultured; Culture Media; Humans; Lectins; Lymphocyte Activation; Neoplasms; Osteosarco | 1979 |
The biochemistry of the citrovorum factor rescue effect in normal bone marrow cells after high-dose methotrexate.
Topics: Adult; Bone Marrow; Cells, Cultured; Deoxyuridine; Humans; Leucovorin; Lymphocytes; Male; Methotrexa | 1979 |
Biological activation of virus-like particles from chemically induced Guinea pig sarcomas.
Topics: Adenoviridae; Animals; Antibody Formation; Bromodeoxyuridine; Cells, Cultured; Concanavalin A; Cultu | 1975 |
Assay of cell-mediated cytotoxicity by tritiated thymidine labeled tumor cells.
Topics: Autoradiography; Cytotoxicity Tests, Immunologic; Fibroblasts; Humans; Immunity, Cellular; Isotope L | 1975 |
New approaches to cancer chemotherapy with methotrexate.
Topics: Adult; Animals; Biological Transport; Bone Marrow; Creatinine; DNA, Neoplasm; Doxorubicin; Drug Ther | 1975 |
Evidence that estrogens modulate activity and increase the number of 1,25-dihydroxyvitamin D receptors in osteoblast-like cells (ROS 17/2.8).
Topics: Animals; Calcitriol; Cell Line; Cytosol; DNA Replication; Estradiol; Kinetics; Osteoblasts; Osteocal | 1992 |
Second messenger signaling in the regulation of cytosolic pH and DNA synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells: role of Na+/H+ exchange.
Topics: Amiloride; Bone Neoplasms; Bucladesine; Calcimycin; Carrier Proteins; DNA, Neoplasm; Dose-Response R | 1992 |
Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.
Topics: Binding, Competitive; Blotting, Northern; Cell Line; DNA Replication; Growth Substances; Humans; Iso | 1992 |
The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells.
Topics: Animals; Bone Neoplasms; Calcium; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; DNA-Binding Pr | 1992 |
Skeletal alkaline phosphatase specific activity is an index of the osteoblastic phenotype in subpopulations of the human osteosarcoma cell line SaOS-2.
Topics: Alkaline Phosphatase; Bone and Bones; Cyclic AMP; Fluorides; Histocytochemistry; Humans; Microbial C | 1991 |
The activation of cAMP-dependent protein kinase is directly linked to the inhibition of osteoblast proliferation (UMR-106) by parathyroid hormone-related protein.
Topics: Animals; Cell Division; Cell Line; DNA Replication; Enzyme Activation; Kinetics; Osteoblasts; Osteos | 1991 |
Aluminum stimulates the proliferation and differentiation of osteoblasts in vitro by a mechanism that is different from fluoride.
Topics: Alkaline Phosphatase; Alum Compounds; Animals; Calcitriol; Cell Division; Cells, Cultured; Chick Emb | 1991 |
Increasing alkaline DNase activity with substrate specificity for denaturated DNA after high dose methotrexate therapy.
Topics: Bone Marrow; Bone Marrow Cells; Child; Deoxyribonucleases; DNA; DNA Damage; Electrophoresis, Polyacr | 1991 |
[Effect by proliferation kinetics of malignant tumors of children of hyperthermia].
Topics: Autoradiography; Bone Neoplasms; Cell Division; Child; Cyclophosphamide; Dactinomycin; Doxorubicin; | 1990 |
Transferrin enhances the antiproliferative effect of aluminum on osteoblast-like cells.
Topics: Aluminum; Animals; Apoproteins; Cell Division; Cell Line; Citrates; Citric Acid; DNA Replication; Dr | 1991 |
Biochemical and morphological analysis of the interaction of epidermal growth factor and parathyroid hormone with UMR 106 osteosarcoma cells.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Count; Dinoprostone; Epidermal Growth Factor; Osmolar Con | 1991 |
Hormonal stimulation of bone cell proliferation.
Topics: Animals; Bone and Bones; Calcitriol; Cell Division; Cells, Cultured; Creatine Kinase; Dinoprostone; | 1990 |
Selective osteoblast mitogens can be extracted from prostatic tissue.
Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Fibroblasts; Growth Substances; Humans; Male; Mit | 1986 |
Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action.
Topics: Amino Acid Sequence; Animals; Bone and Bones; Carrier Proteins; Cell Line; Cells, Cultured; Chickens | 1989 |
Insulin promotes growth of the cultured rat osteosarcoma cell line UMR-106-01: an osteoblast-like cell.
Topics: Animals; Binding, Competitive; Cell Division; Cell Line; Cyclic AMP; DNA, Neoplasm; Insulin; Insulin | 1989 |
Micromolar aluminum levels reduce 3H-thymidine incorporation by cell line UMR 106-01.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Cell Cycle; Cell Division; Cell Line; Chlo | 1989 |
Biochemical characterization of a virus-induced osteosarcoma-like osseous lesion in vitro.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Bone Neoplasms; Calcium; Cartilage; Cell Count; Cel | 1989 |
Osteoblast-like cells secrete granulocyte-macrophage colony-stimulating factor in response to parathyroid hormone and lipopolysaccharide.
Topics: Animals; Cell Division; Cell Line; Colony-Stimulating Factors; DNA Replication; Granulocyte-Macropha | 1989 |
Dexamethasone effects on induction of neoplastic transformation by Fujinami sarcoma virus in an in vitro chick embryo periosteal model for osteosarcoma.
Topics: Alkaline Phosphatase; Animals; Avian Sarcoma Viruses; Bone Neoplasms; Cell Transformation, Neoplasti | 1988 |
Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Hypoxanthine; | 1987 |
Evaluation of fluorescein diacetate for flow cytometric determination of cell viability in orthopaedic research.
Topics: Animals; Cartilage, Articular; Cell Survival; Doxorubicin; Evaluation Studies as Topic; Flow Cytomet | 1988 |
Three tumor sensitivity tests evaluated with mouse tumors.
Topics: Animals; Antineoplastic Agents; Colony-Forming Units Assay; Disease Models, Animal; Lung Neoplasms; | 1987 |
High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines.
Topics: Cell Line; Cell Survival; Deoxyuridine; DNA, Neoplasm; Humans; Leucovorin; Methotrexate; Osteosarcom | 1987 |
In vitro thymidine labelling in human and porcine growth plates.
Topics: Adolescent; Animals; Cell Division; Child; DNA Replication; Growth Plate; Humans; In Vitro Technique | 1985 |
Vitamin A effects on UMR 106 osteosarcoma cells are not mediated by specific cytosolic receptors.
Topics: Alkaline Phosphatase; Animals; Cell Division; Cell Line; Chromatography, Gel; Cytosol; DNA; Osteosar | 1985 |
Circulating immune complexes in human neuroblastoma: direct assay and role in blocking specific cellular immunity.
Topics: Antibodies, Neoplasm; Antibody Specificity; Antigen-Antibody Complex; Antigen-Antibody Reactions; An | 1974 |
Birth, death and net growth of normal, transforming, neoplastic and malignant cell lines. Decrease of death rate in neoplastic alteration.
Topics: Animals; Autoradiography; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; | 1971 |
Lymphocyte blastogenic responses to cultured allogeneic tumor cells in vitro.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Female; Hu | 1972 |
Cell proliferation during immunological perturbation in three transplanted tumours.
Topics: Adenocarcinoma; Animals; Female; In Vitro Techniques; Injections, Intraperitoneal; Lymphoma; Male; M | 1972 |
Cellular cytolysis in vitro: mechanisms underlying a quantitative assay for cellular immunity.
Topics: Animals; Antibody Specificity; Antigens; DNA, Neoplasm; Guinea Pigs; Histocompatibility; Immune Sera | 1972 |
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity.
Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans; | 1973 |
Blastogenic response of normal lymphocytes to cultured lymphoid cells and non-lymphoid neoplastic cells.
Topics: Burkitt Lymphoma; Carcinoma; Cell Line; Cells, Cultured; Humans; Lymphocyte Activation; Lymphocytes; | 1972 |
Hormone therapy: a new approach to osteosarcoma.
Topics: Arginine; Carbohydrate Metabolism; Estradiol; Glucose Tolerance Test; Growth Hormone; Humans; Insuli | 1974 |
Cellular electrophoretic mobility and the mitotic cycle.
Topics: Cell Division; Cold Temperature; Culture Techniques; Electrophoresis; Humans; Neuraminidase; Osteosa | 1966 |
Actinomycin D effects on nucleic acids during tumor regression.
Topics: Animals; Axilla; Carbon Isotopes; Colorimetry; Dactinomycin; DNA; DNA, Neoplasm; Female; Intestine, | 1968 |
[Experimental study of the growth process in osteogenic sarcoma].
Topics: Animals; Autoradiography; Bone Development; DNA, Neoplasm; Femoral Neoplasms; Femur; Male; Mice; Ost | 1968 |