thymidine has been researched along with Opportunistic Infections in 13 studies
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a double-blind, placebo-controlled trial of the efficacy of oral azidothymidine (AZT) in 282 patients with the acquired immunodeficiency syndrome (AIDS) manifested by Pneumocystis carinii pneumonia alone, or with advanced AIDS-related complex." | 9.06 | The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. ( Fischl, MA; Gottlieb, MS; Grieco, MH; Groopman, JE; Laskin, OL; Leedom, JM; Mildvan, D; Richman, DD; Schooley, RT; Volberding, PA, 1987) |
| "Zidovudine (AZT, 3'-azido-3'-deoxythymidine) was shown in a controlled trial to decrease the incidence of mortality, reduce the frequency of opportunistic infections, and provide other clinical benefits to patients with acquired immune deficiency syndrome (AIDS) and advanced AIDS-related complex." | 5.06 | Results of continued monitoring of participants in the placebo-controlled trial of zidovudine for serious human immunodeficiency virus infection. ( Andrews, J; Richman, DD, 1988) |
| "We conducted a double-blind, placebo-controlled trial of the efficacy of oral azidothymidine (AZT) in 282 patients with the acquired immunodeficiency syndrome (AIDS) manifested by Pneumocystis carinii pneumonia alone, or with advanced AIDS-related complex." | 5.06 | The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. ( Fischl, MA; Gottlieb, MS; Grieco, MH; Groopman, JE; Laskin, OL; Leedom, JM; Mildvan, D; Richman, DD; Schooley, RT; Volberding, PA, 1987) |
| " Acyclovir has provided successful treatment in AIDS patients suffering from severe herpes simplex and herpes zoster virus infections." | 3.67 | Management of viral infections in AIDS patients. ( Drucker, JL; King, DH, 1987) |
| "Patients with the acquired immunodeficiency syndrome (AIDS) die of overwhelming infections as a consequence of the destruction of the T4 subset of lymphocytes." | 2.37 | Developmental therapeutics and the acquired immunodeficiency syndrome. ( Broder, S; Chabner, BA; DeVita, VT; Fauci, AS; Kovacs, JA, 1987) |
| "Treatment with zidovudine and weekly infusions of gammaglobulin led to considerable clinical improvement and an almost normal computed tomogram nine weeks later." | 1.27 | AIDS encephalopathy with response to treatment. ( Bird, AG; Matthes, J; Walker, LA; Watson, JG, 1988) |
| "Patients with the acquired immunodeficiency syndrome (AIDS) more commonly have disseminated disease." | 1.27 | Mycobacterium avium complex infection presenting as endobronchial lesions in immunosuppressed patients. ( Cesario, T; Packer, SJ; Williams, JH, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeVita, VT | 1 |
| Broder, S | 1 |
| Fauci, AS | 1 |
| Kovacs, JA | 1 |
| Chabner, BA | 1 |
| Matthes, J | 1 |
| Walker, LA | 1 |
| Watson, JG | 1 |
| Bird, AG | 1 |
| Thurn, JR | 1 |
| Henry, K | 1 |
| Balfour, HH | 1 |
| Hagler, DN | 1 |
| Frame, PT | 1 |
| Drucker, JL | 1 |
| King, DH | 1 |
| Richman, DD | 2 |
| Andrews, J | 1 |
| Packer, SJ | 1 |
| Cesario, T | 1 |
| Williams, JH | 1 |
| Pizzo, PA | 1 |
| Eddy, J | 1 |
| Falloon, J | 1 |
| Balis, FM | 1 |
| Murphy, RF | 1 |
| Moss, H | 1 |
| Wolters, P | 1 |
| Brouwers, P | 1 |
| Jarosinski, P | 1 |
| Rubin, M | 1 |
| Coldiron, BM | 1 |
| Orcutt, VL | 1 |
| Barbaro, DJ | 1 |
| Azon-Masoliver, A | 1 |
| Mallolas, J | 1 |
| Gatell, J | 1 |
| Castel, T | 1 |
| Fischl, MA | 1 |
| Grieco, MH | 1 |
| Gottlieb, MS | 1 |
| Volberding, PA | 1 |
| Laskin, OL | 1 |
| Leedom, JM | 1 |
| Groopman, JE | 2 |
| Mildvan, D | 1 |
| Schooley, RT | 1 |
| Chandrasekar, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV Infection[NCT00001443] | Phase 1 | 63 participants | Interventional | 1995-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thymidine and Opportunistic Infections
| Article | Year |
|---|---|
Developmental therapeutics and the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Deoxyribonucleosides; HIV; Humans; Interferons | 1987 |
AIDS-related Kaposi's sarcoma: therapeutic modalities.
Topics: Acquired Immunodeficiency Syndrome; Bone Marrow Transplantation; Combined Modality Therapy; Doxorubi | 1987 |
3 trials available for thymidine and Opportunistic Infections
| Article | Year |
|---|---|
AIDS. Treatment strategies and the Minnesota AIDS Clinical Trials Unit.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Human | 1988 |
Results of continued monitoring of participants in the placebo-controlled trial of zidovudine for serious human immunodeficiency virus infection.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Double-Blind Method; | 1988 |
The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic | 1987 |
8 other studies available for thymidine and Opportunistic Infections
| Article | Year |
|---|---|
AIDS encephalopathy with response to treatment.
Topics: Antiviral Agents; Brain Diseases; Child, Preschool; gamma-Globulins; HIV Seropositivity; Humans; Mal | 1988 |
Azidothymidine neurotoxicity.
Topics: Acquired Immunodeficiency Syndrome; Adult; Epilepsies, Partial; Humans; Male; Opportunistic Infectio | 1986 |
Management of viral infections in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Herpes | 1987 |
Mycobacterium avium complex infection presenting as endobronchial lesions in immunosuppressed patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Bronchial Diseases; Bronchoscopy; Femal | 1988 |
Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Brain; Brain Diseases; Child; Child, Preschool; Follow-Up Studie | 1988 |
Resolution of resistant chronic herpetic lesions with zidovudine in a patient with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Chronic Disease; Herpes Simplex; Humans; Male; Opportunis | 1988 |
Zidovudine-induced nail pigmentation.
Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Male; Nail Diseases; Opportunistic Infections; Pi | 1988 |
"Cure" of chronic cryptosporidiosis during treatment with azidothymidine in a patient with the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Chronic Disease; Cryptosporidiosis; Diarrhea; Humans; Mal | 1987 |