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thymidine and Nerve Degeneration

thymidine has been researched along with Nerve Degeneration in 34 studies

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Telbivudine is a novel nucleoside drug recently approved for the treatment of patients with chronic hepatitis B."3.74Nonclinical safety profile of telbivudine, a novel potent antiviral agent for treatment of hepatitis B. ( Bridges, EG; Luo, S; Selden, JR, 2008)
"Kainic acid treatment, a model of temporal lobe epilepsy, induces in CA3-CA4 fields of hippocampal complex a neuronal degeneration associated with glial hypertrophy and proliferation."3.69Proliferative astrocytes may express fibronectin-like protein in the hippocampus of epileptic rats. ( Ben-Ari, Y; Jorquera, I; Niquet, J; Represa, A, 1994)
"The ultrastructure of pulse labeled (3-H-thymidine) cells in rat optic nerve undergoing Wallerian degeneration is described."3.65The fine structure of pulse labeled (3-H-thymidine cells) in degenerating rat optic nerve. ( Skoff, RP, 1975)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199023 (67.65)18.7374
1990's8 (23.53)18.2507
2000's3 (8.82)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bridges, EG1
Selden, JR1
Luo, S1
Friede, RL2
Carr, VM3
Simpson, SB1
Hardin, H1
Bernard, A1
Rajas, F1
Fevre-Montange, M1
Derrington, E1
Belin, MF1
Didier-Bazes, M1
Niquet, J1
Jorquera, I1
Ben-Ari, Y1
Represa, A1
Gould, E1
Cameron, HA1
McEwen, BS1
Farbman, AI2
Font, E1
Desfilis, E1
Pérez-Cañellas, M1
Alcántara, S1
García-Verdugo, JM1
Lefèvre, K1
Clarke, PG1
Danthe, EE1
Castagné, V1
Ducray, A1
Bondier, JR1
Michel, G1
Bon, K1
Millot, JL1
Propper, A1
Kastner, A1
McIlwain, DL1
Farel, PB1
Skoff, RP1
Romine, JS1
Bray, GM1
Aguayo, AJ1
Oh, LJ1
Kim, G1
Yu, J1
Robertson, RT1
Smith, CL1
Shatz, CJ1
Sretavan, DW1
Oaklander, AL1
Miller, MS1
Spencer, PS2
Graeber, MB1
Streit, WJ1
Kreutzberg, GW1
Pellegrino, RG2
Politis, MJ2
Ritchie, JM2
Sengelaub, DR1
Dolan, RP1
Finlay, BL1
Johnstone, MA1
Olsson, Y2
Sjöstrand, J2
Gruberg, ER1
Stirling, RV1
Demêmes, D1
Marty, R1
Liu, HM1
Cowan, WM1
Das, GD1
Altman, J1
Murray, RG1
Murray, A1
Kozik, M1
Bradley, WG1
Asbury, AK1
Ule, G1
Kolkmann, FW1

Reviews

2 reviews available for thymidine and Nerve Degeneration

ArticleYear
Interactions between retinal ganglion cells during the development of the mammalian visual system.
    Annual review of neuroscience, 1986, Volume: 9

    Topics: Aging; Animals; Axons; Cats; Cell Communication; Cell Differentiation; Functional Laterality; Genicu

1986
Studies on the development of the avian visual system.
    UCLA forum in medical sciences, 1971, Volume: 14

    Topics: Animals; Autoradiography; Cell Movement; Chick Embryo; Chickens; Denervation; DNA; Eye; Geniculate B

1971

Other Studies

32 other studies available for thymidine and Nerve Degeneration

ArticleYear
Nonclinical safety profile of telbivudine, a novel potent antiviral agent for treatment of hepatitis B.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Administration, Oral; Animals; Antiviral Agents; Carcinogenicity Tests; Dose-Response Relationship,

2008
Incorporation patterns of tritiated thymidine following cutting of the sciatic nerve in rats.
    Journal of neuropathology and experimental neurology, 1967, Volume: 26, Issue:1

    Topics: Animals; Autoradiography; Cell Division; Ganglia, Spinal; Nerve Degeneration; Rats; Sciatic Nerve; S

1967
Rapid appearance of labeled degenerating cells in the dorsal root ganglia after exposure of chick embryos to tritiated thymidine.
    Brain research, 1981, Volume: 254, Issue:1

    Topics: Animals; Autoradiography; Chick Embryo; DNA; Ganglia, Spinal; Nerve Degeneration; Neurons; Thymidine

1981
Modifications of glial metabolism of glutamate after serotonergic neuron degeneration in the hippocampus of the rat.
    Brain research. Molecular brain research, 1994, Volume: 26, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; Animals; Astrocytes; Cell Communication; Fenclonine; Gene Expression; Glial

1994
Proliferative astrocytes may express fibronectin-like protein in the hippocampus of epileptic rats.
    Neuroscience letters, 1994, Oct-10, Volume: 180, Issue:1

    Topics: Animals; Astrocytes; Cell Division; Epilepsy; Fibronectins; Glial Fibrillary Acidic Protein; Hippoca

1994
Blockade of NMDA receptors increases cell death and birth in the developing rat dentate gyrus.
    The Journal of comparative neurology, 1994, Feb-22, Volume: 340, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Brain; Dizocilpine Maleate; Female; Glial Fib

1994
The dynamics of cell death in the olfactory epithelium.
    Experimental neurology, 1993, Volume: 124, Issue:2

    Topics: Animals; Autoradiography; Cell Death; Cell Survival; Epithelial Cells; Kinetics; Nerve Degeneration;

1993
3-Acetylpyridine-induced degeneration and regeneration in the adult lizard brain: a qualitative and quantitative analysis.
    Brain research, 1997, Apr-18, Volume: 754, Issue:1-2

    Topics: Animals; Brain; Cell Nucleus; Cerebral Cortex; DNA; Female; Lizards; Male; Nerve Degeneration; Nerve

1997
Involvement of cyclin-dependent kinases in axotomy-induced retinal ganglion cell death.
    The Journal of comparative neurology, 2002, May-20, Volume: 447, Issue:1

    Topics: Animals; Axotomy; Biomarkers; Bromodeoxyuridine; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Deat

2002
Recovery following peripheral destruction of olfactory neurons in young and adult mice.
    The European journal of neuroscience, 2002, Volume: 15, Issue:12

    Topics: Aging; Animals; Behavior, Animal; Cell Count; Cell Division; Denervation; Discrimination Learning; G

2002
Initiation and time course of mitosis of non-neuronal cells after spinal motoneuron axotomy.
    Brain research, 1979, Dec-14, Volume: 178, Issue:2-3

    Topics: Animals; Anura; Axons; Ganglia, Spinal; Mitosis; Motor Neurons; Nerve Degeneration; Nerve Regenerati

1979
The fine structure of pulse labeled (3-H-thymidine cells) in degenerating rat optic nerve.
    The Journal of comparative neurology, 1975, Jun-15, Volume: 161, Issue:4

    Topics: Animals; Astrocytes; Cell Division; Cell Movement; Male; Monocytes; Nerve Degeneration; Neuroglia; O

1975
Schwann cell multiplication after crush injury of unmyelinated fibers.
    Archives of neurology, 1976, Volume: 33, Issue:1

    Topics: Animals; Autoradiography; Mice; Microscopy, Electron; Mitosis; Nerve Crush; Nerve Degeneration; Schw

1976
Ablation of the olfactory bulb up-regulates the rate of neurogenesis and induces precocious cell death in olfactory epithelium.
    Experimental neurology, 1992, Volume: 115, Issue:1

    Topics: Animals; Autoradiography; Cell Death; DNA Replication; Epithelial Cells; Epithelium; Nerve Degenerat

1992
Transneuronal degeneration of thalamic neurons following deafferentation: quantitative studies using [3H]thymidine autoradiography.
    Brain research. Developmental brain research, 1991, Nov-19, Volume: 63, Issue:1-2

    Topics: Afferent Pathways; Animals; Autoradiography; Cell Count; Eye Enucleation; Inferior Colliculi; Nerve

1991
The critical period for peripheral specification of dorsal root ganglion neurons is related to the period of sensory neurogenesis.
    Developmental biology, 1990, Volume: 142, Issue:2

    Topics: Animals; Autoradiography; Cell Differentiation; Ganglia, Spinal; Nerve Degeneration; Neurons, Affere

1990
Early changes in degenerating mouse sciatic nerve are associated with endothelial cells.
    Brain research, 1987, Sep-01, Volume: 419, Issue:1-2

    Topics: Animals; Cell Division; DNA; Endothelium; Male; Mice; Nerve Degeneration; Ornithine Decarboxylase; P

1987
Formation of microglia-derived brain macrophages is blocked by adriamycin.
    Acta neuropathologica, 1989, Volume: 78, Issue:4

    Topics: Animals; Brain; Cell Division; Doxorubicin; Glial Fibrillary Acidic Protein; Macrophages; Male; Micr

1989
Events in degenerating cat peripheral nerve: induction of Schwann cell S phase and its relation to nerve fibre degeneration.
    Journal of neurocytology, 1986, Volume: 15, Issue:1

    Topics: Animals; Autoradiography; Binding Sites; Cats; Female; Interphase; Male; Mitomycin; Mitomycins; Nerv

1986
Cell generation, death, and retinal growth in the development of the hamster retinal ganglion cell layer.
    The Journal of comparative neurology, 1986, Apr-22, Volume: 246, Issue:4

    Topics: Animals; Animals, Newborn; Autoradiography; Cell Count; Cell Differentiation; Cell Division; Cell Su

1986
The role of post-traumatic mitosis in elevation of anaerobic metabolism enzyme (lactic acid dehydrogenase) activity in degenerating central and peripheral nerve.
    Brain research, 1985, Dec-16, Volume: 359, Issue:1-2

    Topics: Animals; L-Lactate Dehydrogenase; Mitosis; Nerve Degeneration; Optic Nerve Injuries; Rabbits; Rats;

1985
Responses of thymidine labeling of nuclei in gray matter and nerve following sciatic transection.
    Acta neuropathologica, 1967, Jan-02, Volume: 7, Issue:3

    Topics: Animals; Autoradiography; Cell Division; Cell Nucleus; Ganglia, Spinal; Histological Techniques; Mas

1967
Proliferation of mast cells in peripheral nerves during Wallerian degeneration. A radioautographic study.
    Acta neuropathologica, 1969, Volume: 13, Issue:2

    Topics: Animals; Autoradiography; Cell Division; Cell Nucleus; DNA; Mast Cells; Nerve Degeneration; Neurons;

1969
An autoradiographic study of changes in the frog tectum after cutting the optic nerve.
    Brain research, 1974, Aug-16, Volume: 76, Issue:2

    Topics: Animals; Anura; Autoradiography; Cell Division; Cell Movement; Ependyma; Gliosis; Nerve Degeneration

1974
[Radioautographic study of the subependymal plaque in the course of experimental glioses localized in the cerebral cortex].
    Zeitschrift fur mikroskopisch-anatomische Forschung, 1972, Volume: 86, Issue:4

    Topics: Animals; Auditory Cortex; Autoradiography; Brain; Brain Mapping; Cats; Caudate Nucleus; Cell Divisio

1972
Schwann cell properties. II. The identity of phagocytes in the degenerating nerve.
    The American journal of pathology, 1974, Volume: 75, Issue:2

    Topics: Animals; Autoradiography; Axons; Basement Membrane; Male; Microscopy, Electron; Myelin Sheath; Nerve

1974
Studies on the transplantation of developing neural tissue in the mammalian brain. I. Transplantation of cerebellar slabs into the cerebellum of neonate rats.
    Brain research, 1972, Mar-24, Volume: 38, Issue:2

    Topics: Animals; Animals, Newborn; Autoradiography; Cell Differentiation; Cerebellum; Graft Rejection; Mitos

1972
Relations and possible significance of taste bud cells.
    Contributions to sensory physiology, 1971, Volume: 5

    Topics: Animals; Autoradiography; Glossopharyngeal Nerve; Microscopy, Electron; Nerve Degeneration; Nerve Re

1971
Degenerative changes of neurocytes in the light of autoradiographic investigations.
    Pathologia Europaea, 1971, Volume: 6, Issue:2

    Topics: Adenine; Amino Acids; Animals; Autoradiography; Brain; Carbon Isotopes; Cerebral Cortex; Disease Mod

1971
Duration of synthesis phase in neuilemma cells in mouse sciatic nerve during degeneration.
    Experimental neurology, 1970, Volume: 26, Issue:2

    Topics: Animals; Autoradiography; DNA; Mice; Nerve Degeneration; Neurilemma; Schwann Cells; Sciatic Nerve; T

1970
[Experimental studies on Wernicke's encephalopathy].
    Acta neuropathologica, 1968, Nov-01, Volume: 11, Issue:4

    Topics: Acute Disease; Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Diseases; Columbidae; Dem

1968
Origin of macrophages in Wallerian degereration of peripheral nerves demonstrated autoradiographically.
    Experimental neurology, 1969, Volume: 23, Issue:1

    Topics: Animals; Autoradiography; Cell Differentiation; DNA; Female; Leukocyte Count; Leukocytes; Macrophage

1969