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thymidine and Neoplasm Metastasis

thymidine has been researched along with Neoplasm Metastasis in 98 studies

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients."5.30Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997)
"Proliferative activity, evaluated as [3H]thymidine labelling index ([3H]dT LI), and hormone receptors were determined on 97 primary breast cancers and on metachronous lesions from the same patient."3.68Biological characterisation of primary and metachronous lesions in breast cancer patients. ( Coradini, D; Daidone, MG; Di Fronzo, G; Salvadori, B; Silvestrini, R; Valentinis, B, 1992)
"The 3H-thymidine labeling index (LI) was determined on 178 lesions, four of which were primary, from 129 patients with malignant melanoma."3.67Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin. ( Attili, A; Clemente, C; Costa, A; Grignolio, E; Silvestrini, R; Testori, A, 1987)
"Proliferation kinetic parameters of 9 osteogenic sarcomas (6 primary tumours, 3 lung metastases) and 3 Ewing's sarcomas were determined using an autoradiographic in vitro method (single and double labelling with 3H- and 14C-thymidine, and 3H-uridine)."3.66Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children. ( Willnow, U, 1982)
"The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO)."3.65Cell proliferation and histologic classification of bronchogenic carcinoma. ( Borgeskov, S; Dombernowsky, P; Hainau, B; Hansen, HH, 1977)
"Noncurative excision of a primary sc Lewis lung tumor performed on Day 7 or later results in an increase in the thymidine index and growth rate with minimal changes in the cell cycle parameters of the lung metastases."3.65Effects of surgery on the cell kinetics of residual tumor. ( Holmquist, JP; Simpson-Herren, L, 1976)
"Tritiated thymidine incorporation by peripheral human lymphocytes stimulated with phytohemagglutinin (PHA) was investigated in 18 colorectal carcinoma patients (seven with localized tumor and 11 with metastatic tumors)."3.65Phytohemagglutinin-stimulated immune response. Assay in colorectal carcinoma patients. ( Kaplan, MS; Kummerfeld, KB; Lundak, RL; Mino, FO, 1975)
"The in vitro effects of cortisol, estradiol, progesterone, and testosterone on the uptake of tritiated thymidine into the tumor cells of 25 women with primary or metastatic breast cancer were studied and compared with the objective clinical response to ablative endocrine surgery."3.65In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation. ( Burstein, NA; Carey, RW, 1974)
"TP is overexpressed in various tumors and plays an important role in angiogenesis, tumor growth, invasion and metastasis."2.42The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression. ( Akiyama, S; Furukawa, T; Haraguchi, M; Nakajima, Y; Shimaoka, S; Sumizawa, T; Takebayashi, Y, 2004)
"BRCA2 protein depletion after cancer cell adhesion to COL1 or in small RNA interference assays triggers new DNA synthesis, a trophic effect that is abrogated by recombinant BRCA2 expression."1.33Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. ( Arbini, AA; Greco, M; Marra, E; Moro, L, 2005)
"In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients."1.30Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997)
"The number of colonies of hepatic metastasis correlated well with the area under the curve of the distributed amount of the tumor cells in the liver, regardless of the injection route; the correlation line was identical for each injection route."1.30Importance of hepatic first-pass removal in metastasis of colon carcinoma cells. ( Irimura, T; Izumi, Y; Kato, Y; Mizuno, N; Sugiyama, Y, 1998)
"In 173 patients with operable gastric cancer, the relations between thymidine uptake by gastric cancer cells in semi-solid media and their clinicopathologic features as well as their survival lengths were studied."1.29Thymidine uptake in vitro as a prognostic indicator for primary gastric cancer. ( Fujii, H; Masuda, Y; Muraoka, R; Shimomatsuya, T; Tanaka, T; Tanigawa, N, 1993)
"Paradoxically, primary human breast carcinoma cells are difficult to establish in culture: most outgrowths arise from the normal tissue surrounding the tumor."1.28Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. ( Bissell, MJ; Howlett, AR; Petersen, OW; Rønnov-Jessen, L, 1992)
"Tumor sensitivity of ovarian cancer to cytotoxic drugs in vitro was examined between paired samples taken from the primary tumor and its metastases in the same patient."1.28In vitro sensitivity of ovarian cancer as determined by a short-term biochemical assay: comparison between primary and metastatic sites in the same patient. ( Hurst, T; Khoo, SK; Lark, J; Mackay, EV; Parsons, P; Webb, MJ, 1989)
"Why do malignant tumors initially grow rapidly, then more slowly? What accounts for the different rats of growth among different tumors? Can the answers to these and related questions enable us to improve the results of cancer therapy? With advanced technology, we have come a long way in penetrating the mechanisms of tumor cell kinetics, but to date clinical strategies have not kept pace."1.27Biology and tumor growth. ( Tannock, IF, 1983)
" Although the relationship among administered dose, tissue concentration, and therapeutic and/or toxic effects remains extremely complex, a series of experimental and clinical studies provides information on the pharmacokinetic behavior of most anticancer agents in different conditions."1.27Pharmacokinetic studies of anticancer drugs in tumor-bearing animals. ( D'Incalci, M; Donelli, MG; Garattini, S, 1984)
"The ability to form spontaneous metastasis (SM) in the lungs and in other organs appears among cell variants isolated at days 10 to 21 after inoculation."1.27Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity. ( Deichman, GI; Vendrov, EL, 1986)
"The analysis was performed on primary tumors and their synchronous metastases from 67 patients with breast, ovarian, gastrointestinal and germ cell testicular tumors."1.27Drug sensitivity of different tumor lesions from the same patient evaluated by a short-term assay. ( Bolis, G; Daidone, MG; Sanfilippo, O; Seminara, P; Silvestrini, R; Zaffaroni, N, 1988)
" In pharmacokinetic studies in five patients, both schedules produced prolonged plasma beta-half-lives of 5-FU (96-189 minutes)."1.27Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma. ( Chun, H; Kemeny, N; Lynch, G; Martin, D; Young, C, 1985)
"The surgical specimens of breast tumors were incubated in vitro with tritiated thymidine and autoradiographies were performed."1.26Kinetic parameters and the course of the disease in breast cancer. ( Chavaudra, N; Contesso, G; Gioanni, J; Malaise, EP; Pejovic, MJ; Renaud, A; Tubiana, M, 1981)
"tumor, spontaneous metastases, and lung colonies formed after i."1.26Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma. ( Cuman, R; Giraldi, T; Lassiani, L; Nisi, C; Sava, G, 1981)
"1."1.26An approach to the problem of heterogeneity of human tumour-cell populations. ( Sirachý, J, 1979)
"Primary tumors and their metastases in regional lymph nodes show certain differences relative both to the rate of the process and intensity of the DNA synthesis, and relative number of cells with incorporated labelled thymidine."1.25[A kinetic analysis of the growth of transplanted tumors and their metastasis]. ( D'iachkovskaia, RF; Emanuel', NM; Kiseleva, EG; Konovalova, NP; Volkova, IM, 1975)
"Primary tumours and metastases of the same patient frequently showed different sensitivity."1.25[In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)]. ( Bastert, G; Gerner, R; Leppien, G; Michel, RT; Nord, D; Schmidt-Matthiesen, H, 1975)
"The cytokinetics of subcutaneous metastases in five patients with melanoma was studied."1.25Cell proliferation in human melanoma. ( Frei, E; Luce, JK; Shirakawa, S; Tannock, I, 1970)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199079 (80.61)18.7374
1990's12 (12.24)18.2507
2000's7 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davila, M1
Frost, AR1
Grizzle, WE1
Chakrabarti, R1
Shim, BS1
Park, KK1
Choi, SH1
Akiyama, S1
Furukawa, T1
Sumizawa, T1
Takebayashi, Y1
Nakajima, Y1
Shimaoka, S1
Haraguchi, M1
Moro, L1
Arbini, AA1
Marra, E1
Greco, M1
Mazzarino, C1
Nicosia, A1
Garraffo, C1
Tantillo, F1
Monte, V1
Girlando, A1
Malaponte, G1
Qiao, M1
Shapiro, P1
Fosbrink, M1
Rus, H1
Kumar, R1
Passaniti, A1
Thejass, P1
Kuttan, G1
Magrassi, B1
Pagani, G1
Roveta, G1
Tannock, IF1
Sternberg, A1
Petrelli, NJ1
Au, J1
Rustum, Y1
Mittelman, A1
Creaven, P1
Donelli, MG1
D'Incalci, M2
Garattini, S1
Erba, E1
Vaghi, M1
Morasca, L1
Willnow, U2
Meyer, JS1
Tubiana, M3
Pejovic, MJ1
Renaud, A1
Contesso, G1
Chavaudra, N1
Gioanni, J1
Malaise, EP2
Gemsa, D1
Kramer, W1
Napierski, I1
Bärlin, E1
Till, G1
Resch, K1
Giraldi, T1
Sava, G1
Cuman, R1
Nisi, C1
Lassiani, L1
Tanigawa, N1
Masuda, Y1
Shimomatsuya, T1
Fujii, H1
Muraoka, R1
Tanaka, T1
Kikuchi, K1
Nakagawa, H1
Kadono, T1
Etoh, T1
Byers, HR1
Mihm, MC1
Tamaki, K1
Silvestrini, R5
Daidone, MG3
Luisi, A1
Mastore, M1
Leutner, M1
Salvadori, B2
Amadori, D1
Volpi, A1
Maltoni, R1
Nanni, O1
Amaducci, L1
Amadori, A1
Giunchi, DC1
Vio, A1
Saragoni, A1
Bonfil, RD1
Bustuoabad, OD1
Binda, MM1
Mizuno, N1
Kato, Y2
Izumi, Y1
Irimura, T2
Sugiyama, Y2
Shirota, K1
Kondo, H1
Cohen, IR1
Feldman, M1
Emanuel', NM1
Kiseleva, EG1
D'iachkovskaia, RF1
Konovalova, NP1
Volkova, IM1
Hainau, B1
Dombernowsky, P1
Hansen, HH1
Borgeskov, S1
Schiffer, LM2
Braunschweiger, PG1
Stragand, JJ1
Hasegawa, H1
Shapiro, WR1
Posner, JB1
Basler, G1
Woodhead, AD1
Setlow, RB1
Scully, PM1
Sirachý, J1
Frei, E4
Nicolini, C1
Simpson-Herren, L2
Holmquist, JP2
Jaffe, N1
Tattersall, MH1
Pitman, S1
Parker, L1
Bastert, G1
Schmidt-Matthiesen, H1
Gerner, R1
Michel, RT1
Nord, D1
Leppien, G1
Kaplan, MS1
Mino, FO1
Kummerfeld, KB1
Lundak, RL1
Petersen, OW1
Rønnov-Jessen, L1
Howlett, AR1
Bissell, MJ1
Ishiwata, K1
Takahashi, T1
Iwata, R1
Tomura, M1
Tada, M1
Itoh, J1
Kameyama, M1
Ido, T1
Lu, C1
Vickers, MF1
Kerbel, RS2
Valentinis, B1
Di Fronzo, G1
Coradini, D1
Pogány, G1
Cserháti, T1
Oláh, J1
Valkó, K1
Theodorescu, D1
Caltabiano, M1
Greig, R1
Rieman, D1
Courdi, A1
Khoo, SK1
Hurst, T1
Lark, J1
Webb, MJ1
Parsons, P1
Mackay, EV1
Buroker, TR1
Moertel, CG1
Fleming, TR1
Everson, LK1
Cullinan, SA1
Krook, JE1
Mailliard, JA1
Marschke, RF1
Klaassen, DJ1
Laurie, JA1
Deichman, GI1
Vendrov, EL1
Cresson, DH1
Beckman, WC1
Tidwell, RR1
Geratz, JD1
Siegal, GP1
Koscielny, S1
Zaffaroni, N1
Sanfilippo, O1
Bolis, G1
Seminara, P1
Costa, A1
Grignolio, E1
Clemente, C1
Attili, A1
Testori, A1
Nicoletti, G1
Brambilla, P1
De Giovanni, C1
Lollini, PL1
Del Re, B1
Marocchi, A1
Mocarelli, P1
Prodi, G1
Nanni, P1
Lynch, G1
Kemeny, N1
Chun, H1
Martin, D1
Young, C1
Park, SK1
Brody, JI2
Wallace, HA1
Blakemore, WS1
Pisciotta, AV1
Brachetti, A1
Leonhardt, A1
Limburg, H1
Osswald, H1
Schmähl, D1
Wolberg, WH2
Duprez, A1
Bessot, M1
Stempfler, A1
Watkins, E2
Ogata, Y1
Anderson, LL1
Waters, MF1
Choné, B2
Modjanova, EA1
Malenkov, AG1
Blomgren, H1
Glas, U1
Franzén, S1
Granberg, PO1
Dolezalová, V1
Feit, J1
Simícková, M1
Burstein, NA1
Carey, RW1
Muckle, DS1
Mavligit, GM1
Hersh, EM1
McBride, CM1
McCredie, JA1
Inch, WR1
Sutherland, RM1
Buda, JA1
Suciu-Foca, N1
Reemtsma, KB1
Warren, BA1
Straus, MJ1
Kölmel, HW1
Catalona, WJ2
Sample, WF3
Chretien, PB3
Crowder, WL1
Gertner, HR2
Zeidman, I1
Chess, L1
Bock, GN1
Ungaro, PC1
Buchholz, DH1
Mardiney, MR1
Hussa, RO1
Pattillo, RA1
Delfs, FE1
Mattingly, RF1
Pullmann, H1
Steigleder, GK1
Goldman, LI1
Flaxman, BA1
Wernick, G1
Zabriskie, JB1
Sanford, AH1
Huber, C1
Huber, H1
Gföller, A1
Michlamyr, G1
Braunsteiner, H1
Robinson, MR1
Nakhla, LS1
Whitaker, RH1
Yokota, M1
Terz, JJ1
Curutchet, HP1
Lawrence, W1
Tannock, I2
Hagemann, RF1
Owen, LN1
Steel, GG2
Lamerton, LF1
Shirakawa, S1
Luce, JK1
Matovinovic, J1
Nishiyama, RH1
Lalli, A1
Poissant, G1
Hofer, KG1
Hofer, M1
Cleaver, JE1
Fettig, O1
Oehlert, W1
Clarkson, B1
Ota, K1
Ohkita, T1
O'Connor, A1
Karrer, K1
Rubini, JR1

Reviews

7 reviews available for thymidine and Neoplasm Metastasis

ArticleYear
The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.
    Cancer science, 2004, Volume: 95, Issue:11

    Topics: Angiogenesis Inducing Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Ce

2004
Tumor cell population kinetics following noncurative treatment.
    Antibiotics and chemotherapy, 1978, Volume: 23

    Topics: Animals; Cell Division; Humans; Kinetics; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Neoplasm Metasta

1978
Methotrexate revisited.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Alkalies; Aminopterin; Animals; Bone Marrow; Bone Neoplasms; Drug Therapy, Combin

1976
Cell proliferation kinetics in human solid tumors: relation to probability of metastatic dissemination and long-term survival.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1989, Volume: 15, Issue:1

    Topics: Autoradiography; Cell Division; Flow Cytometry; Humans; Interphase; Neoplasm Metastasis; Neoplasms;

1989
Myelopoiesis in vitro.
    Seminars in hematology, 1968, Volume: 5, Issue:3

    Topics: Amino Acids; Animals; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Clone Cells; Colchicine; Cul

1968
Environment of the blood-borne tumor embolus adherent to vessel wall.
    Journal of medicine, 1973, Volume: 4, Issue:3

    Topics: Animals; Aorta; Autoradiography; Basement Membrane; Blood Vessels; Embolism; Endothelium; Fibrin; Fi

1973
The growth characteristics of lung cancer and its application to treatment design.
    Seminars in oncology, 1974, Volume: 1, Issue:3

    Topics: Cell Division; Cell Movement; Humans; Lung Neoplasms; Mitosis; Neoplasm Metastasis; Prognosis; Radio

1974

Trials

1 trial available for thymidine and Neoplasm Metastasis

ArticleYear
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluat

1985

Other Studies

90 other studies available for thymidine and Neoplasm Metastasis

ArticleYear
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.
    The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38

    Topics: Actin Depolymerizing Factors; Cell Division; Cell Line; Cell Line, Tumor; Cell Separation; DNA; DNA-

2003
Anti-metastatic effects of fuzhengfangaitang on human fibrosarcoma cells HT1080.
    The American journal of Chinese medicine, 2003, Volume: 31, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Survival; Fibrosarcoma; Gelatin; Gelatina

2003
Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: BRCA2 Protein; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Collagen Type I; DNA; DNA Repair

2005
Interleukin-2 receptors in patients with lung carcinoma metastasis undergoing treatment with disodium-clodronate. Preliminary research.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Bone Density Conservation Agents; Clodronic Acid; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay;

1989
Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.
    The Journal of biological chemistry, 2006, Mar-17, Volume: 281, Issue:11

    Topics: Animals; Base Sequence; Blotting, Western; Bone Marrow Cells; CDC2 Protein Kinase; Cell Cycle; Cell

2006
Antimetastatic activity of Sulforaphane.
    Life sciences, 2006, May-22, Volume: 78, Issue:26

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen

2006
[Autoradiographic studies with thymidine-H3 in Oberling's aleukemic myeloma in rats, during bone invasion].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Jun-15, Volume: 43, Issue:11

    Topics: Animals; Autoradiography; Bone Neoplasms; DNA; Neoplasm Metastasis; Plasmacytoma; Rats; Thymidine; T

1967
Biology and tumor growth.
    Hospital practice (Office ed.), 1983, Volume: 18, Issue:4

    Topics: Animals; Antineoplastic Agents; Autoradiography; Cell Cycle; Cell Division; Clone Cells; Flow Cytome

1983
A combination of 5-fluorouracil and thymidine in advanced colorectal carcinoma.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Drug Sy

1984
Pharmacokinetic studies of anticancer drugs in tumor-bearing animals.
    Cancer treatment reports, 1984, Volume: 68, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Half-Life; Humans; Kine

1984
In vitro cytotoxicity of VP 16 on primary tumor and metastasis of Lewis lung carcinoma.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms

1982
Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children.
    Archiv fur Geschwulstforschung, 1982, Volume: 52, Issue:1

    Topics: Autoradiography; Child; Culture Techniques; Humans; Kinetics; Neoplasm Metastasis; Osteosarcoma; Sar

1982
Potential value of cell kinetics in management of cancers of unknown origin.
    Seminars in oncology, 1982, Volume: 9, Issue:4

    Topics: Autoradiography; Cell Division; Humans; Kinetics; Neoplasm Metastasis; Neoplasms; Thymidine; Tritium

1982
Kinetic parameters and the course of the disease in breast cancer.
    Cancer, 1981, Mar-01, Volume: 47, Issue:5

    Topics: Breast Neoplasms; Cell Division; Female; Follow-Up Studies; Humans; Kinetics; Neoplasm Metastasis; P

1981
Potentiation of macrophage tumor cytostasis by tumor-induced ascites.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 126, Issue:6

    Topics: Animals; Ascites; Caseins; Cell Transformation, Neoplastic; DNA; Female; Kinetics; Lymphoma; Macroph

1981
Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.
    Cancer research, 1981, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplas

1981
Thymidine uptake in vitro as a prognostic indicator for primary gastric cancer.
    Cancer, 1993, Nov-15, Volume: 72, Issue:10

    Topics: Aged; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Meta

1993
Decreased ET(B) receptor expression in human metastatic melanoma cells.
    Biochemical and biophysical research communications, 1996, Feb-27, Volume: 219, Issue:3

    Topics: Amino Acid Sequence; Cell Line; DNA, Neoplasm; Endothelins; Gene Expression; Humans; Kinetics; Melan

1996
Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index.
    International journal of cancer, 1997, Feb-20, Volume: 74, Issue:1

    Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Cell Division; Confidence Intervals; DNA, Neoplasm

1997
Cell proliferation as a predictor of response to chemotherapy in metastatic breast cancer: a prospective study.
    Breast cancer research and treatment, 1997, Volume: 43, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclop

1997
Antiangiogenesis and apoptosis as mediators of concomitant tumor resistance induced by Calu-6, a human lung carcinoma cell line, in nude mice.
    Oncology research, 1998, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Cell Division; Cell Line; DNA, Neoplasm; Humans; Immunity, Innate; Lung Neoplasm

1998
Importance of hepatic first-pass removal in metastasis of colon carcinoma cells.
    Journal of hepatology, 1998, Volume: 28, Issue:5

    Topics: Animals; Cell Line; Colonic Neoplasms; Humans; Kinetics; Liver Neoplasms; Male; Mathematics; Mice; M

1998
Anti-metastatic effect of the sialyl Lewis-X analog GSC-150 on the human colon carcinoma derived cell line KM12-HX in the mouse.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Line; Colonic Neoplasms; Glycosphingolipids; Hum

2001
Cellular interactions controlling the immune reactivity of T-lymphocytes.
    Annals of the New York Academy of Sciences, 1975, Feb-28, Volume: 249

    Topics: Animals; B-Lymphocytes; Binding Sites, Antibody; Bone Marrow Cells; Cell Differentiation; Concanaval

1975
[A kinetic analysis of the growth of transplanted tumors and their metastasis].
    Voprosy onkologii, 1975, Volume: 21, Issue:7

    Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; DNA, Neoplasm; Kinetics; Liver Neoplasms;

1975
Cell proliferation and histologic classification of bronchogenic carcinoma.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cel

1977
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Drug Evaluation, Preclinical; Ependymoma

1979
Migration of intraperitoneally injected thyroid cells in the Amazon molly, Poecilia formosa.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Autoradiography; Cell Movement; Fishes; Injections, Intraperitoneal; Methods; Neoplasm Meta

1979
An approach to the problem of heterogeneity of human tumour-cell populations.
    British journal of cancer, 1979, Volume: 39, Issue:5

    Topics: Antineoplastic Agents; Cell Nucleus; Chromosomes, Human; Female; Humans; Mitosis; Neoplasm Metastasi

1979
The effect of hyperthermia 42.5 degrees C on the incorporation of 3H-thymidine into the DNA of solid tumours in childhood.
    Archiv fur Geschwulstforschung, 1979, Volume: 49, Issue:5

    Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; DNA, Neoplasm; Humans; In Vitro Techniques; In

1979
The principles and methods of cell synchronization in cancer chemotherapy.
    Biochimica et biophysica acta, 1976, Oct-12, Volume: 458, Issue:3

    Topics: Animals; Cell Division; Cell Line; Colchicine; Computers; Cytarabine; DNA Replication; Esophagus; Hu

1976
Effects of surgery on the cell kinetics of residual tumor.
    Cancer treatment reports, 1976, Volume: 60, Issue:12

    Topics: Animals; Cell Division; Cell Survival; Kinetics; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inb

1976
New approaches to cancer chemotherapy with methotrexate.
    The New England journal of medicine, 1975, Apr-17, Volume: 292, Issue:16

    Topics: Adult; Animals; Biological Transport; Bone Marrow; Creatinine; DNA, Neoplasm; Doxorubicin; Drug Ther

1975
[In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Oct-03, Volume: 100, Issue:40

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Female; Humans; In Vitro T

1975
Phytohemagglutinin-stimulated immune response. Assay in colorectal carcinoma patients.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:10

    Topics: Adult; Aged; Carcinoma; Colonic Neoplasms; Humans; Immunity, Cellular; Lectins; Lymphocytes; Middle

1975
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Oct-01, Volume: 89, Issue:19

    Topics: Basement Membrane; Breast; Breast Neoplasms; Cell Differentiation; Cell Division; Cells, Cultured; C

1992
Tumor diagnosis by PET: potential of seven tracers examined in five experimental tumors including an artificial metastasis model.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Volume: 19, Issue:6

    Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Disease Models, Animal; Floxur

1992
Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Oct-01, Volume: 89, Issue:19

    Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Growth Inhibitors; Humans; Inter

1992
Biological characterisation of primary and metachronous lesions in breast cancer patients.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:12

    Topics: Breast Neoplasms; Cell Division; Female; Humans; Mitosis; Neoplasm Metastasis; Neoplasm Recurrence,

1992
Relationships between the chromatographic retention data and the effects of nucleoside derivatives in highly metastatic 3LL cells.
    Journal of pharmaceutical and biomedical analysis, 1992, Volume: 10, Issue:7

    Topics: Animals; Chromatography, Thin Layer; DNA, Neoplasm; Lung Neoplasms; Neoplasm Metastasis; Nucleosides

1992
Reduction of TGF-beta activity abrogates growth promoting tumor cell-cell interactions in vivo.
    Journal of cellular physiology, 1991, Volume: 148, Issue:3

    Topics: Adenocarcinoma; Animals; Antibodies; Cell Communication; Cell Division; Cell Line; Culture Media, Se

1991
In vitro sensitivity of ovarian cancer as determined by a short-term biochemical assay: comparison between primary and metastatic sites in the same patient.
    Gynecologic oncology, 1989, Volume: 32, Issue:2

    Topics: Cisplatin; Drug Screening Assays, Antitumor; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasms;

1989
Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity.
    International journal of cancer, 1986, Mar-15, Volume: 37, Issue:3

    Topics: Adenoviridae; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cri

1986
In vitro inhibition of human sarcoma cells' invasive ability by bis(5-amidino-2-benzimidazolyl)methane--a novel esteroprotease inhibitor.
    The American journal of pathology, 1986, Volume: 123, Issue:1

    Topics: Amnion; Animals; Benzimidazoles; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Collagen

1986
Cell kinetics, growth rate and the natural history of breast cancer. The Heuson Memorial Lecture.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:1

    Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Interphase; Lymph Nodes; Lymphatic M

1988
Drug sensitivity of different tumor lesions from the same patient evaluated by a short-term assay.
    Tumori, 1988, Apr-30, Volume: 74, Issue:2

    Topics: Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Neoplasm Metastasis;

1988
Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin.
    Cancer, 1987, Dec-01, Volume: 60, Issue:11

    Topics: Adolescent; Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metast

1987
Colony-stimulating activity from the new metastatic TS/A cell line and its high- and low-metastatic clonal derivatives.
    British journal of cancer, 1985, Volume: 52, Issue:2

    Topics: Animals; Bone Marrow; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Fe

1985
Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration

1985
Immunosuppressive effect of surgery.
    Lancet (London, England), 1971, Jan-09, Volume: 1, Issue:7689

    Topics: Adult; Aged; Carbon Isotopes; DNA; Heart Diseases; Humans; Immunity; In Vitro Techniques; Lectins; L

1971
[Clinical experiences with a combination therapy of metastasising genital and mammary carcinomas (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Nov-22, Volume: 116, Issue:47

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Cyclophosphamide; Cytidine; Drug Therapy, Combination; Fem

1974
Determinants of human tumor sensitivity to fluorinated pyrimidine chemotherapy.
    Annals of surgery, 1967, Volume: 166, Issue:4

    Topics: DNA, Neoplasm; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Ligases; Neoplasm Metastasis;

1967
[Determination, on histologic sections, of specific activities of H3-DNA and H3-RNA synthesized in vivo by normal and cancerous human tissues].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1969, Jan-27, Volume: 268, Issue:4

    Topics: Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Gallbladder Neoplasms; Humans; Liver; Liver Neoplasms

1969
Activation of host lymphocytes cultured with cancer cells treated with neuraminidase.
    Nature: New biology, 1971, May-19, Volume: 231, Issue:20

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Culture Tec

1971
Biochemical approaches to prediction of response in solid tumors.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamo

1971
[Results of tumor-cell kinetic studies within the scope of puncture cytology].
    Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1972

    Topics: Acridines; Antineoplastic Agents; Ascitic Fluid; Autoradiography; Biopsy; Cell Movement; Female; Gol

1972
Alteration of properties of cell contacts during progression of hepatomas.
    Experimental cell research, 1973, Volume: 76, Issue:2

    Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cations, Divalent; Cell Adhesion; Cell Separation; Cont

1973
Lymphoid cells in carcinoma of the breast. Failure of response to phytohaemagglutinin in vitro.
    Acta radiologica: therapy, physics, biology, 1973, Volume: 12, Issue:5

    Topics: Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Cells, Cultured

1973
Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma with regard to development of histological changes in liver tissue.
    Neoplasma, 1974, Volume: 21, Issue:4

    Topics: Adenoma, Bile Duct; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Nucleus

1974
In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation.
    Oncology, 1974, Volume: 29, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Aged; Animals; Breast Neoplasms; Carcinoma; Carcin

1974
Response of a musculo-skeletal tumour to combined radiation therapy. An in vitro/vivo investigation.
    Acta radiologica: therapy, physics, biology, 1974, Volume: 13, Issue:4

    Topics: Animals; Cell Line; Glycolysis; Hot Temperature; Lymphatic Metastasis; Methotrexate; Models, Biologi

1974
Lymphocyte blastogenesis induced by autochthonous human solid tumor cells: relationship to stage of disease and serum factors.
    Cancer, 1974, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Antigens, Neoplasm; Blood; Humans; Lymphocyte Activation; Lymphocytes; Neoplasm M

1974
Peripheral blood lymphocytes and breast cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1973, Volume: 107, Issue:2

    Topics: Adult; Age Factors; Breast Neoplasms; Carcinoma; Female; Humans; Leukocyte Count; Lymphocyte Activat

1973
Impaired cell-mediated immunity in patients with cancer.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Breast Neoplasms; Cells, Cultured; Gastrointestinal Neoplasms; Humans; Immunity, Cellular; Lectins;

1974
[Differential cytodiagnosis of tumor cells in cerebrospinal fluid].
    Der Nervenarzt, 1972, Volume: 43, Issue:12

    Topics: Adult; Autoradiography; Carcinoma; Cerebellar Neoplasms; Cerebrospinal Fluid; Cytodiagnosis; Humans;

1972
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage.
    Cancer, 1973, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq

1973
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients.
    Surgery, gynecology & obstetrics, 1973, Volume: 136, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H

1973
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:3

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido

1973
Immunologic effects of BCG in patients with malignant melanoma: specific evidence for stimulation of the 'secondary' immune response.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:1

    Topics: Adult; Antibody Formation; BCG Vaccine; Candida; Complement System Proteins; Female; Humans; Hyperse

1973
Actinomycin D stimulation of HCG production by human choriocarcinoma.
    Obstetrics and gynecology, 1973, Volume: 42, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cattle; Cell Line; Cells, Cultured; Choriocarcinoma; Chorionic Gonado

1973
A study of cellular inflammatory reaction in human malignant melanoma, using in vitro-labelling techniques with h3-thymidine.
    Archiv fur dermatologische Forschung, 1974, Apr-29, Volume: 249, Issue:3

    Topics: Biopsy; Connective Tissue Cells; DNA; Humans; Immunity, Active; Lymphocytes; Macrophages; Mast Cells

1974
Immune surveillance and tumor dissemination: in vitro comparison of the B16 melanoma in primary and metastatic form.
    Surgery, 1974, Volume: 76, Issue:1

    Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells; Cells, Cu

1974
Cell population kinetics of transplanted and metastatic Lewis lung carcinoma.
    Cell and tissue kinetics, 1974, Volume: 7, Issue:4

    Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Hybridization, Genetic; L-Lactate Dehydrogen

1974
[DNS synthesizing lymphocytes in patients with carcinoma].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Autoradiography; Blood Cell Count; Breast Neoplasms; Bronchial Neoplasms; DNA, Neoplasm; Female; His

1971
Inhibition of phytohemagglutinin-induced in vitro lymphocyte transformation by serum from patients with carcinoma.
    Journal of the National Cancer Institute, 1971, Volume: 46, Issue:6

    Topics: ABO Blood-Group System; Adenocarcinoma; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Culture

1971
Lymphocyte transformation inb carcinoma of the prostate.
    British journal of urology, 1971, Volume: 43, Issue:4

    Topics: Acid Phosphatase; Aged; Culture Techniques; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Mal

1971
[A DNA-synthesis inhibiting substance in the human tumor tissues].
    Igaku to seibutsugaku. Medicine and biology, 1971, Jan-10, Volume: 82, Issue:1

    Topics: Amnion; Cell Line; Cell-Free System; Chondroitin; DNA, Neoplasm; Heparin; Humans; Hyaluronic Acid; L

1971
Analysis of the cell kinetics of human solid tumors.
    Cancer, 1971, Volume: 28, Issue:5

    Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo

1971
Possible role of cell kinetics in prediction of the response to cancer therapy.
    National Cancer Institute monograph, 1971, Volume: 34

    Topics: Animals; Antineoplastic Agents; Autoradiography; Drug Resistance; Humans; Mammary Neoplasms, Experim

1971
Cell kinetic analysis of a human melanoma in vitro and in vivo-vitro.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:3

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Carbon Isotopes; Culture Techniques; DNA, Neo

1971
The growth and cell population kinetics of spontaneous tumours in domestic animals.
    British journal of cancer, 1969, Volume: 23, Issue:3

    Topics: Animals; Autoradiography; Cat Diseases; Cats; DNA, Neoplasm; Dog Diseases; Dogs; Female; Kidney Neop

1969
Cell population kinetics and chemotherapy. I. The kinetics of tumor cell populations.
    National Cancer Institute monograph, 1969, Volume: 30

    Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Dog Diseases; Dogs; Humans; Kinetics; Lung N

1969
Cell proliferation in human melanoma.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:6

    Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; DNA, Neoplasm; Female; Humans; Male; Melanoma;

1970
"Benign metastasizing goiter" of Cohnheim: an experimental study with the transplantable thyroid tumor of the rat.
    Cancer research, 1971, Volume: 31, Issue:3

    Topics: Animals; Autoradiography; Cell Differentiation; Cell Transformation, Neoplastic; Diet; Femur; Goiter

1971
Kinetics of proliferation, migration, and death of L1210 ascites cells.
    Cancer research, 1971, Volume: 31, Issue:4

    Topics: Animals; Ascitic Fluid; Autoradiography; Cell Count; Cell Division; Cell Movement; Cell Survival; DN

1971
Defective repair replication of DNA in xeroderma pigmentosum.
    Nature, 1968, May-18, Volume: 218, Issue:5142

    Topics: Autoradiography; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA Replication; Fibroblasts;

1968
[Current data on human tumor kinetics].
    Revue francaise d'etudes cliniques et biologiques, 1969, Volume: 14, Issue:1

    Topics: Animals; Ascites; Biopsy; Humans; Kinetics; Leukemia; Lung Neoplasms; Mammary Neoplasms, Experimenta

1969
[Radioautographic metabolic studies with tritium-labeled substances in tumor tissues of the human uterus].
    Nuclear-Medizin, 1965, Volume: 2

    Topics: Adenocarcinoma; Autoradiography; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Humans; Neoplasm M

1965
Kinetics of proliferation of cancer cells in neoplastic effusions in man.
    Cancer, 1965, Volume: 18, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Autoradiography; Cell Division; DNA, Neoplasm; Exudates and T

1965
On the fate of labelled Ehrlich ascites cells in mice, an autoradiographic study using H3 thymidine.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1965, Volume: 13, Issue:2

    Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; In Vitro Techniques; Injections,

1965