thymidine has been researched along with Necrosis in 107 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A single intravenous injection of 4-hydroxyaminoquinoline-1-oxide (4-HAQO) induced a dose-dependent diffuse pancreatic acinar cell necrosis within 48 hours after the administration in rats." | 7.67 | Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats. ( Okamura, K, 1989) |
| "Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis." | 7.67 | Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989) |
| "Azathioprine is an immunosuppressant drug widely used." | 5.32 | Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004) |
| "Cystamine post-treatment, therefore, does not appear to inhibit toxicant-induced influx of extracellular calcium into toxicant-damaged cells." | 5.27 | Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine. ( Gandolfi, AJ; MacDonald, JR; Sipes, IG, 1986) |
| " The modeled structure of the enzyme was used for docking selective inhibitors (nucleotide analogs and the non-nucleoside inhibitor aphidicolin) in its active site in order to design new drugs for actinic keratosis and squamous cell carcinoma (SCC)." | 3.76 | Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives. ( Dugovic, B; Höltje, HD; Höltje, M; Kleuser, B; Korting, HC; Murruzzu, C; Reissig, HU; Richartz, A; Schäfer-Korting, M; Schwanke, A; Zdrazil, B, 2010) |
| "A single intravenous injection of 4-hydroxyaminoquinoline-1-oxide (4-HAQO) induced a dose-dependent diffuse pancreatic acinar cell necrosis within 48 hours after the administration in rats." | 3.67 | Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats. ( Okamura, K, 1989) |
| "Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis." | 3.67 | Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989) |
| "Reutilization of thymidine (TdR) and 5-iodo-2'-deoxyuridine (I-UdR) released by dying tumour cells was assayed in the syngeneic adenocarcinoma EO 771 by injecting heat killed, labelled tumour cells into tumours." | 3.67 | Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique. ( Feinendegen, LE; Mühlensiepen, H; Porschen, R; Porschen, W, 1987) |
| "After an initial episode of acute tubular necrosis, apparent resistance to gentamicin nephrotoxicity develops in rats during prolonged drug administration." | 3.67 | Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function. ( Bennett, WM; Gilbert, DN; Houghton, DC; Lee, D, 1986) |
| " The increase was of the same degree seen after ethionine necrosis." | 3.64 | Autoradiographic labelling of pancreatic acinar cells with thymidine-H3 during degeneration and regeneration. ( FITZGERALD, PJ, 1963) |
| "Acute lymphoblastic leukemia (ALL) with mixed lineage leukemia (MLL) gene rearrangements (MLL+ALL) has a dismal prognosis and is characterized by high surface CD44 expression." | 1.46 | Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression. ( Abe, M; Ando, N; Furuichi, Y; Goi, K; Inukai, T; Kagami, K; Kasai, S; Nagano, O; Nakane, T; Ohno, S; Okazaki, S; Saitoh, S; Saya, H; Sugita, K, 2017) |
| "Tacrine has been shown to accumulate within mitochondria, and it particularly targets mtDNA." | 1.32 | Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver. ( Berson, A; Demeilliers, C; Descatoire, V; Feldmann, G; Fromenty, B; Haouzi, D; Mansouri, A; Pessayre, D; Sutton, A; Vadrot, N, 2003) |
| "Azathioprine is an immunosuppressant drug widely used." | 1.32 | Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004) |
| " We studied cytotoxic effects of selected toxic light chains in further detail." | 1.31 | Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells. ( Batuman, V; Meleg-Smith, S; Pote, A; Simon, EE; Zwizinski, C, 2000) |
| "Necrosis is limited to superficial, fully differentiated mucoid cells, which--after the cell death has occurred--are desquamated into the lumen as fragments of irregular shape." | 1.29 | Analysis of the cell death in the mucoid epithelium of mouse stomach. ( Pipan, N; Sterle, M, 1994) |
| "Hydroxyurea (HU) is a swiftly acting cytotoxic teratogen and an inhibitor of DNA synthesis." | 1.28 | The nature of the embryo-protective interaction of propyl gallate with hydroxyurea. ( DeSesso, JM; Goeringer, GC, 1990) |
| "Necrosis was evident in the differentiating epithelial elements forming the cuticle, cortex, and inner root sheath." | 1.28 | Minoxidil stimulates mouse vibrissae follicles in organ culture. ( Buhl, AE; Holland, JM; Kawabe, TT; Waldon, DJ, 1989) |
| "(125I) Iododeoxyuridine labeling of a squamous cell carcinoma and follow-up of 125I activity at the tumor in situ revealed that the 125I activity remained at a constant level from the 24th to the 100th hour post-labeling and then decreased with a half time of about 200 hr." | 1.28 | [Transition of oxic cells to hypoxic cells in a murine squamous cell carcinoma]. ( Takai, Y, 1989) |
| " Furthermore, chronic administration of 0." | 1.27 | Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. ( Denda, A; Emi, Y; Konishi, Y; Mikami, S; Nakae, D; Ohnishi, T; Takahashi, S; Yokose, Y, 1984) |
| "Cystamine post-treatment, therefore, does not appear to inhibit toxicant-induced influx of extracellular calcium into toxicant-damaged cells." | 1.27 | Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine. ( Gandolfi, AJ; MacDonald, JR; Sipes, IG, 1986) |
| "The proliferative rate of breast carcinoma appears to be an important determinant of morphologic patterns." | 1.27 | Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study. ( Babcock, DS; McDivitt, RW; Meyer, JS; Prey, MU, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 80 (74.77) | 18.7374 |
| 1990's | 9 (8.41) | 18.2507 |
| 2000's | 13 (12.15) | 29.6817 |
| 2010's | 5 (4.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kasai, S | 1 |
| Furuichi, Y | 1 |
| Ando, N | 1 |
| Kagami, K | 1 |
| Abe, M | 1 |
| Nakane, T | 1 |
| Goi, K | 1 |
| Inukai, T | 1 |
| Saitoh, S | 1 |
| Ohno, S | 1 |
| Okazaki, S | 1 |
| Nagano, O | 1 |
| Saya, H | 1 |
| Sugita, K | 1 |
| Bemis, JC | 1 |
| Bryce, SM | 1 |
| Nern, M | 1 |
| Raschke, M | 1 |
| Sutter, A | 1 |
| Höltje, M | 1 |
| Richartz, A | 1 |
| Zdrazil, B | 1 |
| Schwanke, A | 1 |
| Dugovic, B | 1 |
| Murruzzu, C | 1 |
| Reissig, HU | 1 |
| Korting, HC | 1 |
| Kleuser, B | 1 |
| Höltje, HD | 1 |
| Schäfer-Korting, M | 1 |
| Lafontant, PJ | 1 |
| Burns, AR | 1 |
| Grivas, JA | 1 |
| Lesch, MA | 1 |
| Lala, TD | 1 |
| Reuter, SP | 1 |
| Field, LJ | 1 |
| Frounfelter, TD | 1 |
| Wang, J | 1 |
| Wang, M | 1 |
| Huang, Y | 1 |
| Chattopadhyay, S | 1 |
| Bhaumik, S | 1 |
| Purkayastha, M | 1 |
| Basu, S | 1 |
| Nag Chaudhuri, A | 1 |
| Das Gupta, S | 1 |
| Mansouri, A | 1 |
| Haouzi, D | 1 |
| Descatoire, V | 1 |
| Demeilliers, C | 1 |
| Sutton, A | 1 |
| Vadrot, N | 1 |
| Fromenty, B | 1 |
| Feldmann, G | 1 |
| Pessayre, D | 1 |
| Berson, A | 1 |
| FITZGERALD, PJ | 1 |
| ZEMAN, W | 1 |
| WARAVDEKAR, VS | 1 |
| SASLAW, LD | 1 |
| JONES, WA | 1 |
| LEEVY, CM | 2 |
| TEN-HOVE, W | 1 |
| FRANK, O | 1 |
| BAKER, H | 1 |
| Menor, C | 1 |
| Fernández-Moreno, MD | 1 |
| Fueyo, JA | 1 |
| Escribano, O | 1 |
| Olleros, T | 1 |
| Arriaza, E | 1 |
| Cara, C | 1 |
| Lorusso, M | 1 |
| Di Paola, M | 1 |
| Román, ID | 1 |
| Guijarro, LG | 1 |
| Schmittgen, TD | 1 |
| Gissel, KA | 1 |
| Zakrajsek, BA | 1 |
| Lawrence, BP | 1 |
| Liu, Q | 1 |
| Jupe, ER | 1 |
| Lerner, MR | 1 |
| Do, SV | 1 |
| Brackett, DJ | 1 |
| Schepers, MS | 2 |
| van Ballegooijen, ES | 2 |
| Bangma, CH | 2 |
| Verkoelen, CF | 2 |
| O'Connor, KC | 1 |
| Muhitch, JW | 1 |
| Lacks, DJ | 1 |
| Al-Rubeai, M | 1 |
| Barbour, KW | 1 |
| Berger, FG | 1 |
| Gao, L | 1 |
| Yu, S | 1 |
| Wu, Y | 1 |
| Shan, B | 1 |
| Seo, JM | 1 |
| Kim, TJ | 1 |
| Jin, YR | 1 |
| Han, HJ | 1 |
| Ryu, CK | 1 |
| Sheen, YY | 1 |
| Kim, DW | 1 |
| Yun, YP | 1 |
| Zetterlund, CG | 1 |
| Takahashi, S | 1 |
| Nakae, D | 1 |
| Yokose, Y | 1 |
| Emi, Y | 1 |
| Denda, A | 1 |
| Mikami, S | 1 |
| Ohnishi, T | 1 |
| Konishi, Y | 1 |
| Thomas, WA | 1 |
| Kim, DN | 1 |
| Lee, KT | 1 |
| Reiner, JM | 1 |
| Schmee, J | 1 |
| Lea, MA | 1 |
| Sumas, ME | 1 |
| Randolph, V | 1 |
| Sinzinger, H | 1 |
| Firbas, W | 1 |
| Cromwell, M | 1 |
| Hakkinen, PJ | 1 |
| Haschek, WM | 1 |
| Camplejohn, RS | 1 |
| Schultze, B | 3 |
| Maurer, W | 3 |
| Yavorkovsky, L | 1 |
| Lai, E | 1 |
| Ilic, Z | 1 |
| Sell, S | 1 |
| Abrahamsson, SO | 1 |
| Gelberman, R | 1 |
| Sterle, M | 1 |
| Pipan, N | 1 |
| Kubota, R | 1 |
| Kubota, K | 1 |
| Yamada, S | 1 |
| Tada, M | 1 |
| Ido, T | 1 |
| Tamahashi, N | 1 |
| Hoshi, K | 1 |
| Honda, S | 1 |
| Endo, C | 1 |
| Sato, A | 1 |
| Sekimoto, S | 1 |
| Ferrer, I | 1 |
| Alcántara, S | 1 |
| Catalá, I | 1 |
| Zújar, MJ | 1 |
| Jyonouchi, H | 1 |
| Sun, S | 1 |
| Abiru, T | 1 |
| Chareancholvanich, S | 1 |
| Ingbar, DH | 1 |
| Wang, T | 1 |
| Fontenot, RD | 1 |
| Soni, MG | 1 |
| Bucci, TJ | 1 |
| Mehendale, HM | 1 |
| Pote, A | 1 |
| Zwizinski, C | 1 |
| Simon, EE | 1 |
| Meleg-Smith, S | 1 |
| Batuman, V | 1 |
| Hedberg, KM | 1 |
| Dellheden, B | 1 |
| Wikstrand, CJ | 1 |
| Fredman, P | 1 |
| Fiume, L | 1 |
| Mattioli, A | 1 |
| Balboni, PG | 1 |
| Tognon, M | 1 |
| Barbanti-Brodano, G | 1 |
| de Vries, J | 1 |
| Wieland, T | 1 |
| Barkla, DH | 1 |
| Tutton, PJ | 1 |
| Bagheri, SA | 1 |
| Bolt, MG | 1 |
| Boyer, JL | 1 |
| Palmer, RH | 1 |
| Koch, HK | 1 |
| Agostini, B | 1 |
| Lesch, R | 2 |
| Mohr, W | 1 |
| Bock, G | 1 |
| Lossnitzer, K | 1 |
| Aspegren, K | 1 |
| Scarpelli, DG | 1 |
| Frankfurt, OS | 1 |
| DeSesso, JM | 1 |
| Goeringer, GC | 1 |
| Hall, J | 1 |
| Brésil, H | 1 |
| Serres, M | 1 |
| Martel-Planche, G | 1 |
| Wild, CP | 1 |
| Montesano, R | 1 |
| Buhl, AE | 1 |
| Waldon, DJ | 1 |
| Kawabe, TT | 1 |
| Holland, JM | 1 |
| Okamura, K | 1 |
| Benjamin, IJ | 1 |
| Jalil, JE | 1 |
| Tan, LB | 1 |
| Cho, K | 1 |
| Weber, KT | 1 |
| Clark, WA | 1 |
| Takai, Y | 1 |
| Amenta, JS | 1 |
| Baccino, FM | 1 |
| Bell, RS | 1 |
| Bourret, LA | 1 |
| Bell, DF | 1 |
| Gebhardt, MC | 1 |
| Rosenberg, A | 1 |
| Berrey, HB | 1 |
| Treadwell, BV | 1 |
| Tomford, WW | 1 |
| Mankin, HJ | 1 |
| Horowitz, SM | 1 |
| Frondoza, CG | 1 |
| Lennox, DW | 1 |
| Piérard-Franchimont, C | 1 |
| Damseaux, M | 1 |
| Mélotte, P | 1 |
| Piérard, GE | 1 |
| Porschen, R | 1 |
| Porschen, W | 1 |
| Mühlensiepen, H | 1 |
| Feinendegen, LE | 1 |
| MacDonald, JR | 1 |
| Gandolfi, AJ | 1 |
| Sipes, IG | 1 |
| Mitrovic, DR | 1 |
| Garcia, F | 1 |
| Front, P | 1 |
| Guillermet, V | 1 |
| Meyer, JS | 1 |
| Prey, MU | 1 |
| Babcock, DS | 1 |
| McDivitt, RW | 1 |
| Houghton, DC | 1 |
| Lee, D | 1 |
| Gilbert, DN | 1 |
| Bennett, WM | 1 |
| Tannock, IF | 2 |
| Helpap, B | 6 |
| Cremer, H | 3 |
| Rogers, AE | 1 |
| Newberne, PM | 1 |
| Argot, J | 1 |
| Malsberger, RG | 1 |
| Reutter, W | 1 |
| Deppler, D | 1 |
| Decker, K | 1 |
| Gerhard, H | 2 |
| Schump, E | 1 |
| Hughes, WF | 1 |
| Sasaki, T | 1 |
| Morris, HP | 2 |
| Baserga, R | 3 |
| Looney, WB | 1 |
| Mayo, AA | 1 |
| Janners, MY | 1 |
| Mellon, JG | 1 |
| Allen, P | 1 |
| Salak, D | 1 |
| Rousseau, MF | 1 |
| Nabarra, B | 1 |
| Nezelof, C | 1 |
| Ludwin, SK | 1 |
| Northway, WH | 1 |
| Bensch, KG | 1 |
| Beneke, G | 1 |
| Harbitz, TB | 1 |
| Hassler, O | 1 |
| Rockwell, SC | 1 |
| Kallman, RF | 1 |
| Fajardo, LF | 1 |
| Ofeigsson, OJ | 1 |
| Mitchell, R | 1 |
| Patrick, RS | 1 |
| Cuppage, FE | 3 |
| Chiga, M | 2 |
| Tate, A | 3 |
| Peel, S | 1 |
| Cowen, DM | 1 |
| Raick, AN | 1 |
| Burdzy, K | 1 |
| Pound, AW | 1 |
| Horn, L | 1 |
| Lawson, TA | 1 |
| Chen, TS | 1 |
| Oberpriller, JO | 1 |
| Oberpriller, JC | 1 |
| Yamashita, K | 1 |
| Breining, H | 3 |
| Lymberopoulos, S | 3 |
| Webster, WS | 1 |
| Bishop, SP | 1 |
| Geer, JC | 1 |
| Minderjahn, A | 1 |
| Sigel, B | 1 |
| Baldia, LB | 1 |
| Brightman, SA | 1 |
| Dunn, MR | 1 |
| Price, RI | 1 |
| Like, AA | 1 |
| Chick, WL | 1 |
| Rickenbacher, J | 1 |
| Campobasso, O | 1 |
| Berrino, F | 1 |
| Lala, PK | 1 |
| Stoughton, RB | 1 |
| Grouls, V | 1 |
| Stewart, BW | 1 |
| Magee, PN | 1 |
| Witzleben, CL | 1 |
| Cunningham, N | 1 |
| Snodgrass, MJ | 1 |
| Hanna, MG | 1 |
| Rabes, H | 1 |
| Tuczek, HV | 1 |
| Ule, G | 1 |
| Kolkmann, FW | 1 |
| Farber, E | 1 |
| Hambrick, GW | 1 |
| Handwerger, RL | 1 |
| Betts, A | 1 |
| Sewall, EL | 1 |
| Tanguay, R | 1 |
| Estensen, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 DiabetesL a Open-label Trial[NCT02502071] | Phase 4 | 45 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Urine uric acid crystals were identified by polarized microscopy (Polarized light imaging Zeiss Axiovert 135; 0.3NA objective), and pictures were captured from each urine sample. UA crystals were defined dichotomously as being present or absent. (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
| Intervention | participants (Number) | |
|---|---|---|
| Day 1 (pre-therapy) | Day 2 (post-therapy) | |
| Sodium Bicarbonate | 14 | 3 |
Urine uric acid were evaluated using a QuantiChrom UA kit assay (DIUA-250) with quantitative colorimetric UA determination at 590 nm (BioAssay System, California, USA). (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
| Intervention | mg/dl (Geometric Mean) | |
|---|---|---|
| Day 1 (pre-therapy) | Day 2 (post-therapy) | |
| Sodium Bicarbonate | 23.81 | 22.30 |
3 reviews available for thymidine and Necrosis
| Article | Year |
|---|---|
Proteolysis and cell death.
Topics: Ammonium Chloride; Animals; Cell Survival; Cells, Cultured; Cyanides; DNA; Freezing; Mice; Necrosis; | 1989 |
Treatment of herpes simplex keratitis. A review.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Animals; Antimetabolites; Cautery; Child; Child, Prescho | 1969 |
[Age-determination of injuries of internal organs].
Topics: Adipose Tissue; Animals; Autoradiography; Bites and Stings; Connective Tissue Cells; Forensic Medici | 1972 |
104 other studies available for thymidine and Necrosis
| Article | Year |
|---|---|
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.
Topics: Biological Transport; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Female; Gene Express | 2017 |
Best practices for application of attachment cells to in vitro micronucleus assessment by flow cytometry.
Topics: Animals; Apoptosis; Azides; Cell Culture Techniques; Cells, Cultured; Cricetinae; DNA Damage; Flow C | 2016 |
Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives.
Topics: Aphidicolin; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; DNA Polymera | 2010 |
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration.
Topics: Animals; Cell Proliferation; Deoxyuridine; Disease Models, Animal; Granulation Tissue; Inflammation; | 2012 |
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases.
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivud | 2013 |
Apoptosis and necrosis in developing brain cells due to arsenic toxicity and protection with antioxidants.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Brain; Cell Division; Cell Membrane; Cell Survival; Chela | 2002 |
Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver.
Topics: Animals; Apoptosis; DNA; DNA Fragmentation; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA | 2003 |
Autoradiographic labelling of pancreatic acinar cells with thymidine-H3 during degeneration and regeneration.
Topics: Acinar Cells; Animals; Autoradiography; Cell Nucleus; DNA; Ethionine; Histones; Necrosis; Pancreas; | 1963 |
DISTURBANCES OF NUCLEIC ACID METABOLISM PRECEDING DELAYED RADIONECROSIS OF NERVOUS TISSUE.
Topics: Cell Division; Metabolism; Necrosis; Neurochemistry; Radiation Injuries; Radiation Injuries, Experim | 1963 |
HEPATIC CHANGES INDUCED BY AN AQUEOUS EXTRACT OF ULTRAVIOLET-IRRADIATED LINOLENIC ACID.
Topics: alpha-Linolenic Acid; Autoradiography; Chemical and Drug Induced Liver Injury; Fatty Acids; Fatty Ac | 1964 |
FOLIC ACID DEFICIENCY AND HEPATIC DNA SYNTHESIS.
Topics: Avitaminosis; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; Folic Aci | 1964 |
Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine.
Topics: Acetylcysteine; Animals; Apoptosis; Azathioprine; Caspase 3; Caspases; Cell Survival; Cytochromes c; | 2004 |
Diverse gene expression pattern during 5-fluorouridine-induced apoptosis.
Topics: Analysis of Variance; Apoptosis; Cell Survival; Cluster Analysis; Colorectal Neoplasms; Flow Cytomet | 2005 |
Crystals cause acute necrotic cell death in renal proximal tubule cells, but not in collecting tubule cells.
Topics: Animals; Apoptosis; Calcium Oxalate; Crystallization; Culture Media; Dinoprostone; Dogs; Humans; Hyd | 2005 |
Oxalate is toxic to renal tubular cells only at supraphysiologic concentrations.
Topics: Animals; Apoptosis; Calcium Oxalate; Cell Count; Cell Line; Crystallization; Dinoprostone; Dogs; Dos | 2005 |
Modeling suppression of cell death by Bcl-2 over-expression in myeloma NS0 6A1 cells.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Computational Biology; Gene Expression Regul | 2006 |
Cell death in response to antimetabolites directed at thymidylate synthase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bl | 2008 |
Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Electric Stimulation; Fema | 2007 |
YSK2821, a newly synthesized indoledione derivative, inhibits cell proliferation and cell cycle progression via the cell cycle-related proteins by regulating phosphatidylinositol-3 kinase cascade in vascular smooth muscle cells.
Topics: Apoptosis; Blotting, Western; Cell Count; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Prolifer | 2008 |
Behaviour and fate of a buried graft of small intestine. An experimental study.
Topics: Acid Phosphatase; Animals; Autoradiography; Bile Ducts; Dogs; Duodenum; Epithelium; Galactosidases; | 1967 |
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats.
Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; gamma-Glutamyltransferase; Liver; Liver Neoplas | 1984 |
Population dynamics of arterial cells during atherogenesis. XIII. Mitogenic and cytotoxic effects of a hyperlipidemic (HL) diet on cells in advanced lesions in the abdominal aortas of swine fed an HL diet for 270-345 days.
Topics: Aging; Animals; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Cell Survival; Cholesterol; Die | 1983 |
DNA in cytosol fractions obtained by differential centrifugation of homogenates of rapidly growing liver tumors.
Topics: Animals; Cell Nucleus; Cell Separation; Centrifugation; Cytosol; DNA; DNA, Neoplasm; Female; Hydroxy | 1984 |
Radiation induced alterations in rabbit aortic prostacyclin formation.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Dose-Response Relationship, Radiation; Epoprostenol; Nec | 1982 |
Pulmonary toxicity of methylcyclopentadienyl manganese tricarbonyl: nonciliated bronchiolar epithelial (Clara) cell necrosis and alveolar damage in the mouse, rat, and hamster.
Topics: Animals; Bronchi; Cricetinae; DNA; Epithelium; Female; Male; Manganese Poisoning; Mesocricetus; Mice | 1982 |
An in vivo double labelling study of the subsequent fate of cells arrested in metaphase by vincristine in the JB-1 mouse ascites tumour.
Topics: Animals; Cell Cycle; Cell Survival; Female; Interphase; Metaphase; Mice; Mitosis; Necrosis; Neoplasm | 1980 |
Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol.
Topics: 1-Propanol; alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Biomarkers; Cell Division; Desmin; | 1995 |
Maintenance of the gliding surface of tendon autografts in dogs.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Dogs; Necrosis; Scintillation Counting; Tend | 1994 |
Analysis of the cell death in the mucoid epithelium of mouse stomach.
Topics: Animals; Apoptosis; Autoradiography; Carbohydrate Metabolism; Cell Differentiation; Cell Nucleus; Cy | 1994 |
Active and passive mechanisms of [fluorine-18] fluorodeoxyglucose uptake by proliferating and prenecrotic cancer cells in vivo: a microautoradiographic study.
Topics: Animals; Autoradiography; Cell Cycle; Cell Division; Deoxyglucose; DNA, Neoplasm; Female; Fluorine R | 1994 |
Wound healing process in the portio vaginalis uteri after CO2-laser treatment.
Topics: Cervix Uteri; DNA; Epithelium; Female; Humans; Hydroxyproline; Hyperplasia; Laser Therapy; Necrosis; | 1993 |
Experimentally induced laminar necrosis, status verrucosus, focal cortical dysplasia reminiscent of microgyria, and porencephaly in the rat.
Topics: Animals; Animals, Newborn; Autoradiography; Biomarkers; Brain; Cerebral Cortex; Disease Models, Anim | 1993 |
The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Cell Count; Cell Line; Cell Survival; Epithelial Cells; Huma | 1998 |
Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, | 2000 |
Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells.
Topics: Apoptosis; Cell Death; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Immunologic; | 2000 |
Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro.
Topics: Antibodies, Monoclonal; Cell Division; Central Nervous System Neoplasms; Drug Screening Assays, Anti | 2000 |
Enhanced inhibition of virus DNA synthesis in hepatocytes by trifluorothymidine coupled to asialofetuin.
Topics: alpha-Fetoproteins; Animals; Bone Marrow; Deoxycytidine; DNA; DNA, Viral; Ectromelia virus; Ectromel | 1979 |
Ultrastructure of 1,2-dimethylhydrazine-induced adenocarcinomas in rat colon.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Nucleus; Colonic Neop | 1978 |
Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate.
Topics: Animals; Biliary Tract; Chenodeoxycholic Acid; Cholic Acids; Common Bile Duct; Deoxycholic Acid; Dos | 1978 |
[The topography of rat liver cell necrosis and proliferation after sublethal phalloidinintoxication of adult and newborn rats (author's transl)].
Topics: Animals; Animals, Newborn; Chemical and Drug Induced Liver Injury; Hemorrhage; Liver; Liver Regenera | 1978 |
Skeletal muscle regeneration in myopathic hamsters of strain BIO 8262.
Topics: Animals; Autoradiography; Cricetinae; Muscles; Muscular Diseases; Necrosis; Regeneration; Thymidine; | 1976 |
7,12-DMBA induced rat mammary tumour studied for hormonal responsiveness in vitro. 2. Organ cultures.
Topics: Animals; Benz(a)Anthracenes; Cell Division; Cell Survival; Depression, Chemical; DNA, Neoplasm; Estr | 1975 |
Preliminary observations on the mitogenic effect of cyclopropenoid fatty acids on rat pancreas.
Topics: Animals; Cell Nucleus; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Endoplasmic Reticulum; | 1975 |
[Acute cell death in various sections of the gastrointestinal tract in DNA synthesis inhibition].
Topics: Animals; Autoradiography; Cell Survival; Digestive System; DNA; Dose-Response Relationship, Drug; Dr | 1975 |
The nature of the embryo-protective interaction of propyl gallate with hydroxyurea.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Embryo, Mammalian; Female; Hydroxyurea; Injections; Necro | 1990 |
Modulation of O6-methylguanine-DNA methyltransferase in rat and hamster liver after treatment with dimethylnitrosamine.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Kinetics; Liver; Ma | 1990 |
Minoxidil stimulates mouse vibrissae follicles in organ culture.
Topics: Animals; Cell Differentiation; Cysteine; Epidermis; Glycine; Keratins; Mice; Minoxidil; Necrosis; Or | 1989 |
Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats.
Topics: 4-Hydroxyaminoquinoline-1-oxide; Aminoquinolines; Animals; Autoradiography; Male; Necrosis; Pancreas | 1989 |
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Cardiomegaly; DNA; DNA Replication; Fibrosis; Hear | 1989 |
[Transition of oxic cells to hypoxic cells in a murine squamous cell carcinoma].
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Idoxuridine; Iodine Radioisotopes; | 1989 |
Necrotising myopathy and zidovudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Male; Muscular Diseases; Necrosis; Thymid | 1988 |
Evaluation of fluorescein diacetate for flow cytometric determination of cell viability in orthopaedic research.
Topics: Animals; Cartilage, Articular; Cell Survival; Doxorubicin; Evaluation Studies as Topic; Flow Cytomet | 1988 |
Effects of polymethylmethacrylate exposure upon macrophages.
Topics: Animals; Cytotoxicity, Immunologic; DNA; Macrophages; Methylmethacrylates; Necrosis; Thymidine; Tumo | 1988 |
The fate of hypodermis after liposuction surgery.
Topics: Adipose Tissue; Adult; Autoradiography; Epidermis; Female; Fibrosis; Humans; Lipectomy; Necrosis; Sk | 1988 |
Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique.
Topics: Adenocarcinoma; Animals; Cell Survival; Idoxuridine; Iodine Radioisotopes; Male; Mammary Neoplasms, | 1987 |
Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine.
Topics: Administration, Oral; Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride; Cystamine; DNA; | 1986 |
Histochemical and cellular changes induced in the rabbit knee joint by an intraarticular implantation of a sheet of polyethylene.
Topics: Animals; Bone and Bones; Cartilage, Articular; Cell Survival; Disease Models, Animal; Foreign-Body R | 1985 |
Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Cell Cycle; Estradiol; Female; Humans; Lymph Nodes; Middl | 1986 |
Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function.
Topics: Acute Kidney Injury; Autoradiography; Drug Resistance; Gentamicins; Glomerular Filtration Rate; Hist | 1986 |
Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.
Topics: Animals; Autoradiography; Capillaries; Connective Tissue; Fibroblasts; Kinetics; Mammary Neoplasms, | 1970 |
[Light microscopic and autoradiographic studies on the cellular reaction of the liver after catgut implantation].
Topics: Animals; Autoradiography; Chromium; DNA; Liver; Mice; Necrosis; Protein Biosynthesis; Sutures; Thymi | 1970 |
Lasiocarpine: factors influencing its toxicity and effects on liver cell division.
Topics: Acetates; Alkaloids; Amides; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Dealkylat | 1971 |
Intracellular replication of infectious pancreatic necrosis virus.
Topics: Acridines; Animals; Cells, Cultured; Cytoplasm; DNA; Fibroblasts; Fish Diseases; Fishes; Inclusion B | 1972 |
[Histological and autoradiographic investigations of the galactosamine induced hepatitis of the rat].
Topics: Animals; Autoradiography; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; DNA; Hep | 1969 |
[Autoradiographic investigation of proliferation and polyploidization during CCl4-induced liver regeneration in mice (author's transl)].
Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Cell Division; Liver; Liver Regeneration; | 1973 |
The cell cycles of three transplantable Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Liver Neoplasms; Mitosis; Necro | 1970 |
Cell proliferation and tumor growth in hepatomas 3924A.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Connective Tissue; Female; Liver Neoplasms; Mit | 1971 |
Behaviour of Wilms tumour and normal metanephros in organ culture.
Topics: Age Factors; Autoradiography; Blood Vessels; Cell Differentiation; Cell Membrane; Cell Survival; Cel | 1974 |
Oxygen toxicity in the newborn. Necrotizing bronchiolitis in mice exposed to 100 per cent oxygen.
Topics: Animals; Animals, Newborn; Bronchi; Bronchitis; Cilia; Endoplasmic Reticulum; Lung; Mice; Mice, Inbr | 1974 |
Organ culture of benign nodular hyperplasia of human prostate in chemically-defined medium.
Topics: Aged; Autoradiography; Culture Media; Demecolcine; DNA; Histological Techniques; Humans; Hyperplasia | 1973 |
[Effect of a second CCl 4 -intoxication on CCl 4 -damaged mouse liver].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Nucleus; Chemic | 1972 |
Cell renewal in aortic necrosis following orthostatic collapse. An experimental autoradiographic study in the rabbit using 3 H-thymidine.
Topics: Animals; Aortic Diseases; Autoradiography; Endothelium; Hypotension, Orthostatic; Male; Muscle, Smoo | 1973 |
Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative.
Topics: Animals; Antigens, Neoplasm; Autoradiography; Cell Line; Cell Survival; Cells, Cultured; Computers; | 1972 |
Observations on the cold water treatment of cutaneous burns.
Topics: Animals; Back; Burns; Cell Nucleus; Collagen; Connective Tissue; Connective Tissue Cells; Cryosurger | 1972 |
Mitochondrial proliferation within the nephron. I. Comparison of mitochondrial hyperplasia of tubular regeneration with compensatory hypertrophy.
Topics: Animals; Autoradiography; Cell Nucleus; DNA, Mitochondrial; Epithelial Cells; Hyperplasia; Hypertrop | 1973 |
A quantitative morphological analysis of the response of a transplantable rat fibrosarcoma to cyclophosphamide.
Topics: Animals; Cell Nucleus; Cyclophosphamide; Cytoplasm; Erythrocytes; Fibrosarcoma; Leukocytes; Mitosis; | 1973 |
Ultrastructural and biochemical changes induced in mouse epidermis by a hyperplastic agent, ethylphenylpropiolate.
Topics: Animals; Cell Differentiation; Cell Division; Cell Nucleolus; Chromatin; Cytoplasm; DNA; Endoplasmic | 1973 |
Decreased toxicity of dimethylnitrosamine in rats after treatment with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylamines; DNA; Kidney; | 1973 |
Liver regeneration and uraemia.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Lectins; Liver; Liver Re | 1973 |
Response of the adult newt ventricle to injury.
Topics: Animals; Autoradiography; Blood Coagulation; DNA Replication; Endocardium; Heart Injuries; Heart Ven | 1974 |
[Autoradiographic studies with H3-thymidine in the rat spleen after cryonecrosis].
Topics: Animals; Autoradiography; Cell Division; Cicatrix; Cryosurgery; Freezing; Granulation Tissue; Necros | 1974 |
Experimental aortic intimal thickening. I. Morphology and source of intimal cells.
Topics: Animals; Aorta; Autoradiography; Cell Count; Cell Movement; DNA; Electrocoagulation; Endoplasmic Ret | 1974 |
[Wound healing of kidney after cryonecrosis. Autoradiographic investigations with 3H-thymidine on rats (authors transl)].
Topics: Animals; Autoradiography; Fibroblasts; Freezing; Kidney; Kidney Diseases; Kidney Tubules; Leukocytes | 1974 |
Effect of blood flow reversal in liver autotransplants upon the site of hepatocyte regeneration.
Topics: Animals; Autoradiography; Biopsy; Carotid Arteries; DNA; Dogs; Female; Histological Techniques; Jugu | 1968 |
Studies in the diabetic mutant mouse. II. Electron microscopy of pancreatic islets.
Topics: Animals; Autoradiography; Cytoplasmic Granules; Diabetes Mellitus; Disease Models, Animal; Endoplasm | 1970 |
The importance of the regulation for the normal and abnormal development. Experimental investigations on the limb buds of chick embryos.
Topics: Animals; Chick Embryo; Congenital Abnormalities; Electrocoagulation; Embryo, Mammalian; Embryo, Nonm | 1968 |
[Cell proliferation after traumatic injuries of the liver].
Topics: Animals; Autoradiography; Cell Division; Liver; Liver Regeneration; Mice; Necrosis; Thymidine; Triti | 1970 |
Cell cycle studies in the regenerating rat nephron following injury with mercuric chloride.
Topics: Acute Kidney Injury; Animals; DNA; Kidney Tubules; Male; Mercury; Mitosis; Necrosis; Rats; Regenerat | 1972 |
Early effects of cyclophosphamide on mouse bladder epithelium.
Topics: Acute Disease; Animals; Cell Nucleus; Chronic Disease; Cyclophosphamide; Cystitis; DNA; Epithelial C | 1972 |
Age-specific changes in the proliferation of Ehrlich ascites tumor cells grown as solid tumors.
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Survival; DNA, Neoplasm; Female; In Vitro T | 1972 |
[Cell proliferation in cryonecrotic liver].
Topics: Animals; Autoradiography; Cell Division; Fibroblasts; Freezing; Kupffer Cells; Liver; Necrosis; Rats | 1972 |
Effect of hydroxyurea and cytarabine on rodent epidermal cells.
Topics: Animals; Animals, Newborn; Cell Nucleus; Cytarabine; Depression, Chemical; DNA Replication; Hydroxyu | 1971 |
[Reutilization of labeled DNA building blocks in wound healing].
Topics: Animals; Autoradiography; DNA; Granulation Tissue; Liver Diseases; Liver Regeneration; Mice; Necrosi | 1971 |
Effect of a single dose of dimethylnitrosamine on biosynthesis of nucleic acid and protein in rat liver and kidney.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; DNA; Female; Kidney; Kidney Neoplasms; L | 1971 |
The pathogenesis of iron hepatotoxicity.
Topics: Alloxan; Animals; Autoradiography; Blood Glucose; Chemical and Drug Induced Liver Injury; Ethionine; | 1969 |
Nucleic acid synthesis in the regenerating nephron following injury with mercuric chloride.
Topics: Animals; Autoradiography; DNA; Kidney Tubules; Male; Mercury; Microscopy, Electron; Mitomycins; Mito | 1969 |
Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue. 3. Alterations in the thymic-dependent area induced by the passenger lactic dehydrogenase virus.
Topics: Animals; Immunity, Cellular; L-Lactate Dehydrogenase; Lymphocytes; Lymphoid Tissue; Male; Mice; Micr | 1970 |
[Cell proliferation in the partially resected rat liver after acute intoxication by allyl formate].
Topics: Animals; Autoradiography; Cell Division; DNA; Formates; Hepatectomy; Liver; Liver Regeneration; Male | 1971 |
The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour.
Topics: Animals; Autoradiography; Blood Vessels; Female; Growth; Hyperbaric Oxygenation; Hypoxia; Mammary Ne | 1968 |
[Experimental studies on Wernicke's encephalopathy].
Topics: Acute Disease; Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Diseases; Columbidae; Dem | 1968 |
Differential effects of hydroxyurea on survival of proliferating cells in vivo.
Topics: Animals; Cell Biology; Depression, Chemical; DNA; Epithelial Cells; Folic Acid; Hydroxyurea; Intesti | 1969 |
The behavior of explants of psoriasis in vitro.
Topics: Chlorides; Culture Media; Culture Techniques; DNA; Glucosamine; Heparin; Histocytochemistry; Humans; | 1969 |
The effect of necrosis and tumor on the cell kinetics of small bowel.
Topics: Animals; Autoradiography; Cell Division; Cricetinae; Fibrosarcoma; In Vitro Techniques; Jejunum; Nec | 1966 |
Puromycin-induced necrosis of crypt cells of the small intestine of mouse.
Topics: Animals; Antimetabolites; Autoradiography; Cell Division; Cytarabine; Dactinomycin; DNA; Heart; Inte | 1966 |