thymidine has been researched along with Necrosis in 107 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Excerpt | Relevance | Reference |
---|---|---|
"A single intravenous injection of 4-hydroxyaminoquinoline-1-oxide (4-HAQO) induced a dose-dependent diffuse pancreatic acinar cell necrosis within 48 hours after the administration in rats." | 7.67 | Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats. ( Okamura, K, 1989) |
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis." | 7.67 | Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989) |
"Azathioprine is an immunosuppressant drug widely used." | 5.32 | Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004) |
"Cystamine post-treatment, therefore, does not appear to inhibit toxicant-induced influx of extracellular calcium into toxicant-damaged cells." | 5.27 | Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine. ( Gandolfi, AJ; MacDonald, JR; Sipes, IG, 1986) |
" The modeled structure of the enzyme was used for docking selective inhibitors (nucleotide analogs and the non-nucleoside inhibitor aphidicolin) in its active site in order to design new drugs for actinic keratosis and squamous cell carcinoma (SCC)." | 3.76 | Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives. ( Dugovic, B; Höltje, HD; Höltje, M; Kleuser, B; Korting, HC; Murruzzu, C; Reissig, HU; Richartz, A; Schäfer-Korting, M; Schwanke, A; Zdrazil, B, 2010) |
"A single intravenous injection of 4-hydroxyaminoquinoline-1-oxide (4-HAQO) induced a dose-dependent diffuse pancreatic acinar cell necrosis within 48 hours after the administration in rats." | 3.67 | Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats. ( Okamura, K, 1989) |
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis." | 3.67 | Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989) |
"Reutilization of thymidine (TdR) and 5-iodo-2'-deoxyuridine (I-UdR) released by dying tumour cells was assayed in the syngeneic adenocarcinoma EO 771 by injecting heat killed, labelled tumour cells into tumours." | 3.67 | Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique. ( Feinendegen, LE; Mühlensiepen, H; Porschen, R; Porschen, W, 1987) |
"After an initial episode of acute tubular necrosis, apparent resistance to gentamicin nephrotoxicity develops in rats during prolonged drug administration." | 3.67 | Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function. ( Bennett, WM; Gilbert, DN; Houghton, DC; Lee, D, 1986) |
" The increase was of the same degree seen after ethionine necrosis." | 3.64 | Autoradiographic labelling of pancreatic acinar cells with thymidine-H3 during degeneration and regeneration. ( FITZGERALD, PJ, 1963) |
"Acute lymphoblastic leukemia (ALL) with mixed lineage leukemia (MLL) gene rearrangements (MLL+ALL) has a dismal prognosis and is characterized by high surface CD44 expression." | 1.46 | Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression. ( Abe, M; Ando, N; Furuichi, Y; Goi, K; Inukai, T; Kagami, K; Kasai, S; Nagano, O; Nakane, T; Ohno, S; Okazaki, S; Saitoh, S; Saya, H; Sugita, K, 2017) |
"Tacrine has been shown to accumulate within mitochondria, and it particularly targets mtDNA." | 1.32 | Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver. ( Berson, A; Demeilliers, C; Descatoire, V; Feldmann, G; Fromenty, B; Haouzi, D; Mansouri, A; Pessayre, D; Sutton, A; Vadrot, N, 2003) |
"Azathioprine is an immunosuppressant drug widely used." | 1.32 | Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. ( Arriaza, E; Cara, C; Di Paola, M; Escribano, O; Fernández-Moreno, MD; Fueyo, JA; Guijarro, LG; Lorusso, M; Menor, C; Olleros, T; Román, ID, 2004) |
" We studied cytotoxic effects of selected toxic light chains in further detail." | 1.31 | Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells. ( Batuman, V; Meleg-Smith, S; Pote, A; Simon, EE; Zwizinski, C, 2000) |
"Necrosis is limited to superficial, fully differentiated mucoid cells, which--after the cell death has occurred--are desquamated into the lumen as fragments of irregular shape." | 1.29 | Analysis of the cell death in the mucoid epithelium of mouse stomach. ( Pipan, N; Sterle, M, 1994) |
"Hydroxyurea (HU) is a swiftly acting cytotoxic teratogen and an inhibitor of DNA synthesis." | 1.28 | The nature of the embryo-protective interaction of propyl gallate with hydroxyurea. ( DeSesso, JM; Goeringer, GC, 1990) |
"Necrosis was evident in the differentiating epithelial elements forming the cuticle, cortex, and inner root sheath." | 1.28 | Minoxidil stimulates mouse vibrissae follicles in organ culture. ( Buhl, AE; Holland, JM; Kawabe, TT; Waldon, DJ, 1989) |
"(125I) Iododeoxyuridine labeling of a squamous cell carcinoma and follow-up of 125I activity at the tumor in situ revealed that the 125I activity remained at a constant level from the 24th to the 100th hour post-labeling and then decreased with a half time of about 200 hr." | 1.28 | [Transition of oxic cells to hypoxic cells in a murine squamous cell carcinoma]. ( Takai, Y, 1989) |
" Furthermore, chronic administration of 0." | 1.27 | Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. ( Denda, A; Emi, Y; Konishi, Y; Mikami, S; Nakae, D; Ohnishi, T; Takahashi, S; Yokose, Y, 1984) |
"Cystamine post-treatment, therefore, does not appear to inhibit toxicant-induced influx of extracellular calcium into toxicant-damaged cells." | 1.27 | Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine. ( Gandolfi, AJ; MacDonald, JR; Sipes, IG, 1986) |
"The proliferative rate of breast carcinoma appears to be an important determinant of morphologic patterns." | 1.27 | Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study. ( Babcock, DS; McDivitt, RW; Meyer, JS; Prey, MU, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 80 (74.77) | 18.7374 |
1990's | 9 (8.41) | 18.2507 |
2000's | 13 (12.15) | 29.6817 |
2010's | 5 (4.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kasai, S | 1 |
Furuichi, Y | 1 |
Ando, N | 1 |
Kagami, K | 1 |
Abe, M | 1 |
Nakane, T | 1 |
Goi, K | 1 |
Inukai, T | 1 |
Saitoh, S | 1 |
Ohno, S | 1 |
Okazaki, S | 1 |
Nagano, O | 1 |
Saya, H | 1 |
Sugita, K | 1 |
Bemis, JC | 1 |
Bryce, SM | 1 |
Nern, M | 1 |
Raschke, M | 1 |
Sutter, A | 1 |
Höltje, M | 1 |
Richartz, A | 1 |
Zdrazil, B | 1 |
Schwanke, A | 1 |
Dugovic, B | 1 |
Murruzzu, C | 1 |
Reissig, HU | 1 |
Korting, HC | 1 |
Kleuser, B | 1 |
Höltje, HD | 1 |
Schäfer-Korting, M | 1 |
Lafontant, PJ | 1 |
Burns, AR | 1 |
Grivas, JA | 1 |
Lesch, MA | 1 |
Lala, TD | 1 |
Reuter, SP | 1 |
Field, LJ | 1 |
Frounfelter, TD | 1 |
Wang, J | 1 |
Wang, M | 1 |
Huang, Y | 1 |
Chattopadhyay, S | 1 |
Bhaumik, S | 1 |
Purkayastha, M | 1 |
Basu, S | 1 |
Nag Chaudhuri, A | 1 |
Das Gupta, S | 1 |
Mansouri, A | 1 |
Haouzi, D | 1 |
Descatoire, V | 1 |
Demeilliers, C | 1 |
Sutton, A | 1 |
Vadrot, N | 1 |
Fromenty, B | 1 |
Feldmann, G | 1 |
Pessayre, D | 1 |
Berson, A | 1 |
FITZGERALD, PJ | 1 |
ZEMAN, W | 1 |
WARAVDEKAR, VS | 1 |
SASLAW, LD | 1 |
JONES, WA | 1 |
LEEVY, CM | 2 |
TEN-HOVE, W | 1 |
FRANK, O | 1 |
BAKER, H | 1 |
Menor, C | 1 |
Fernández-Moreno, MD | 1 |
Fueyo, JA | 1 |
Escribano, O | 1 |
Olleros, T | 1 |
Arriaza, E | 1 |
Cara, C | 1 |
Lorusso, M | 1 |
Di Paola, M | 1 |
Román, ID | 1 |
Guijarro, LG | 1 |
Schmittgen, TD | 1 |
Gissel, KA | 1 |
Zakrajsek, BA | 1 |
Lawrence, BP | 1 |
Liu, Q | 1 |
Jupe, ER | 1 |
Lerner, MR | 1 |
Do, SV | 1 |
Brackett, DJ | 1 |
Schepers, MS | 2 |
van Ballegooijen, ES | 2 |
Bangma, CH | 2 |
Verkoelen, CF | 2 |
O'Connor, KC | 1 |
Muhitch, JW | 1 |
Lacks, DJ | 1 |
Al-Rubeai, M | 1 |
Barbour, KW | 1 |
Berger, FG | 1 |
Gao, L | 1 |
Yu, S | 1 |
Wu, Y | 1 |
Shan, B | 1 |
Seo, JM | 1 |
Kim, TJ | 1 |
Jin, YR | 1 |
Han, HJ | 1 |
Ryu, CK | 1 |
Sheen, YY | 1 |
Kim, DW | 1 |
Yun, YP | 1 |
Zetterlund, CG | 1 |
Takahashi, S | 1 |
Nakae, D | 1 |
Yokose, Y | 1 |
Emi, Y | 1 |
Denda, A | 1 |
Mikami, S | 1 |
Ohnishi, T | 1 |
Konishi, Y | 1 |
Thomas, WA | 1 |
Kim, DN | 1 |
Lee, KT | 1 |
Reiner, JM | 1 |
Schmee, J | 1 |
Lea, MA | 1 |
Sumas, ME | 1 |
Randolph, V | 1 |
Sinzinger, H | 1 |
Firbas, W | 1 |
Cromwell, M | 1 |
Hakkinen, PJ | 1 |
Haschek, WM | 1 |
Camplejohn, RS | 1 |
Schultze, B | 3 |
Maurer, W | 3 |
Yavorkovsky, L | 1 |
Lai, E | 1 |
Ilic, Z | 1 |
Sell, S | 1 |
Abrahamsson, SO | 1 |
Gelberman, R | 1 |
Sterle, M | 1 |
Pipan, N | 1 |
Kubota, R | 1 |
Kubota, K | 1 |
Yamada, S | 1 |
Tada, M | 1 |
Ido, T | 1 |
Tamahashi, N | 1 |
Hoshi, K | 1 |
Honda, S | 1 |
Endo, C | 1 |
Sato, A | 1 |
Sekimoto, S | 1 |
Ferrer, I | 1 |
Alcántara, S | 1 |
Catalá, I | 1 |
Zújar, MJ | 1 |
Jyonouchi, H | 1 |
Sun, S | 1 |
Abiru, T | 1 |
Chareancholvanich, S | 1 |
Ingbar, DH | 1 |
Wang, T | 1 |
Fontenot, RD | 1 |
Soni, MG | 1 |
Bucci, TJ | 1 |
Mehendale, HM | 1 |
Pote, A | 1 |
Zwizinski, C | 1 |
Simon, EE | 1 |
Meleg-Smith, S | 1 |
Batuman, V | 1 |
Hedberg, KM | 1 |
Dellheden, B | 1 |
Wikstrand, CJ | 1 |
Fredman, P | 1 |
Fiume, L | 1 |
Mattioli, A | 1 |
Balboni, PG | 1 |
Tognon, M | 1 |
Barbanti-Brodano, G | 1 |
de Vries, J | 1 |
Wieland, T | 1 |
Barkla, DH | 1 |
Tutton, PJ | 1 |
Bagheri, SA | 1 |
Bolt, MG | 1 |
Boyer, JL | 1 |
Palmer, RH | 1 |
Koch, HK | 1 |
Agostini, B | 1 |
Lesch, R | 2 |
Mohr, W | 1 |
Bock, G | 1 |
Lossnitzer, K | 1 |
Aspegren, K | 1 |
Scarpelli, DG | 1 |
Frankfurt, OS | 1 |
DeSesso, JM | 1 |
Goeringer, GC | 1 |
Hall, J | 1 |
Brésil, H | 1 |
Serres, M | 1 |
Martel-Planche, G | 1 |
Wild, CP | 1 |
Montesano, R | 1 |
Buhl, AE | 1 |
Waldon, DJ | 1 |
Kawabe, TT | 1 |
Holland, JM | 1 |
Okamura, K | 1 |
Benjamin, IJ | 1 |
Jalil, JE | 1 |
Tan, LB | 1 |
Cho, K | 1 |
Weber, KT | 1 |
Clark, WA | 1 |
Takai, Y | 1 |
Amenta, JS | 1 |
Baccino, FM | 1 |
Bell, RS | 1 |
Bourret, LA | 1 |
Bell, DF | 1 |
Gebhardt, MC | 1 |
Rosenberg, A | 1 |
Berrey, HB | 1 |
Treadwell, BV | 1 |
Tomford, WW | 1 |
Mankin, HJ | 1 |
Horowitz, SM | 1 |
Frondoza, CG | 1 |
Lennox, DW | 1 |
Piérard-Franchimont, C | 1 |
Damseaux, M | 1 |
Mélotte, P | 1 |
Piérard, GE | 1 |
Porschen, R | 1 |
Porschen, W | 1 |
Mühlensiepen, H | 1 |
Feinendegen, LE | 1 |
MacDonald, JR | 1 |
Gandolfi, AJ | 1 |
Sipes, IG | 1 |
Mitrovic, DR | 1 |
Garcia, F | 1 |
Front, P | 1 |
Guillermet, V | 1 |
Meyer, JS | 1 |
Prey, MU | 1 |
Babcock, DS | 1 |
McDivitt, RW | 1 |
Houghton, DC | 1 |
Lee, D | 1 |
Gilbert, DN | 1 |
Bennett, WM | 1 |
Tannock, IF | 2 |
Helpap, B | 6 |
Cremer, H | 3 |
Rogers, AE | 1 |
Newberne, PM | 1 |
Argot, J | 1 |
Malsberger, RG | 1 |
Reutter, W | 1 |
Deppler, D | 1 |
Decker, K | 1 |
Gerhard, H | 2 |
Schump, E | 1 |
Hughes, WF | 1 |
Sasaki, T | 1 |
Morris, HP | 2 |
Baserga, R | 3 |
Looney, WB | 1 |
Mayo, AA | 1 |
Janners, MY | 1 |
Mellon, JG | 1 |
Allen, P | 1 |
Salak, D | 1 |
Rousseau, MF | 1 |
Nabarra, B | 1 |
Nezelof, C | 1 |
Ludwin, SK | 1 |
Northway, WH | 1 |
Bensch, KG | 1 |
Beneke, G | 1 |
Harbitz, TB | 1 |
Hassler, O | 1 |
Rockwell, SC | 1 |
Kallman, RF | 1 |
Fajardo, LF | 1 |
Ofeigsson, OJ | 1 |
Mitchell, R | 1 |
Patrick, RS | 1 |
Cuppage, FE | 3 |
Chiga, M | 2 |
Tate, A | 3 |
Peel, S | 1 |
Cowen, DM | 1 |
Raick, AN | 1 |
Burdzy, K | 1 |
Pound, AW | 1 |
Horn, L | 1 |
Lawson, TA | 1 |
Chen, TS | 1 |
Oberpriller, JO | 1 |
Oberpriller, JC | 1 |
Yamashita, K | 1 |
Breining, H | 3 |
Lymberopoulos, S | 3 |
Webster, WS | 1 |
Bishop, SP | 1 |
Geer, JC | 1 |
Minderjahn, A | 1 |
Sigel, B | 1 |
Baldia, LB | 1 |
Brightman, SA | 1 |
Dunn, MR | 1 |
Price, RI | 1 |
Like, AA | 1 |
Chick, WL | 1 |
Rickenbacher, J | 1 |
Campobasso, O | 1 |
Berrino, F | 1 |
Lala, PK | 1 |
Stoughton, RB | 1 |
Grouls, V | 1 |
Stewart, BW | 1 |
Magee, PN | 1 |
Witzleben, CL | 1 |
Cunningham, N | 1 |
Snodgrass, MJ | 1 |
Hanna, MG | 1 |
Rabes, H | 1 |
Tuczek, HV | 1 |
Ule, G | 1 |
Kolkmann, FW | 1 |
Farber, E | 1 |
Hambrick, GW | 1 |
Handwerger, RL | 1 |
Betts, A | 1 |
Sewall, EL | 1 |
Tanguay, R | 1 |
Estensen, RD | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 DiabetesL a Open-label Trial[NCT02502071] | Phase 4 | 45 participants (Actual) | Interventional | 2017-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Urine uric acid crystals were identified by polarized microscopy (Polarized light imaging Zeiss Axiovert 135; 0.3NA objective), and pictures were captured from each urine sample. UA crystals were defined dichotomously as being present or absent. (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
Intervention | participants (Number) | |
---|---|---|
Day 1 (pre-therapy) | Day 2 (post-therapy) | |
Sodium Bicarbonate | 14 | 3 |
Urine uric acid were evaluated using a QuantiChrom UA kit assay (DIUA-250) with quantitative colorimetric UA determination at 590 nm (BioAssay System, California, USA). (NCT02502071)
Timeframe: Day 1 (pre-therapy) and Day 2 (post-therapy)
Intervention | mg/dl (Geometric Mean) | |
---|---|---|
Day 1 (pre-therapy) | Day 2 (post-therapy) | |
Sodium Bicarbonate | 23.81 | 22.30 |
3 reviews available for thymidine and Necrosis
Article | Year |
---|---|
Proteolysis and cell death.
Topics: Ammonium Chloride; Animals; Cell Survival; Cells, Cultured; Cyanides; DNA; Freezing; Mice; Necrosis; | 1989 |
Treatment of herpes simplex keratitis. A review.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Animals; Antimetabolites; Cautery; Child; Child, Prescho | 1969 |
[Age-determination of injuries of internal organs].
Topics: Adipose Tissue; Animals; Autoradiography; Bites and Stings; Connective Tissue Cells; Forensic Medici | 1972 |
104 other studies available for thymidine and Necrosis
Article | Year |
---|---|
Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers necrosis of B-precursor leukemia cells with high surface CD44 expression.
Topics: Biological Transport; Cell Line, Tumor; Cell Survival; Child; Child, Preschool; Female; Gene Express | 2017 |
Best practices for application of attachment cells to in vitro micronucleus assessment by flow cytometry.
Topics: Animals; Apoptosis; Azides; Cell Culture Techniques; Cells, Cultured; Cricetinae; DNA Damage; Flow C | 2016 |
Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives.
Topics: Aphidicolin; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; DNA Polymera | 2010 |
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration.
Topics: Animals; Cell Proliferation; Deoxyuridine; Disease Models, Animal; Granulation Tissue; Inflammation; | 2012 |
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases.
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivud | 2013 |
Apoptosis and necrosis in developing brain cells due to arsenic toxicity and protection with antioxidants.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Brain; Cell Division; Cell Membrane; Cell Survival; Chela | 2002 |
Tacrine inhibits topoisomerases and DNA synthesis to cause mitochondrial DNA depletion and apoptosis in mouse liver.
Topics: Animals; Apoptosis; DNA; DNA Fragmentation; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA | 2003 |
Autoradiographic labelling of pancreatic acinar cells with thymidine-H3 during degeneration and regeneration.
Topics: Acinar Cells; Animals; Autoradiography; Cell Nucleus; DNA; Ethionine; Histones; Necrosis; Pancreas; | 1963 |
DISTURBANCES OF NUCLEIC ACID METABOLISM PRECEDING DELAYED RADIONECROSIS OF NERVOUS TISSUE.
Topics: Cell Division; Metabolism; Necrosis; Neurochemistry; Radiation Injuries; Radiation Injuries, Experim | 1963 |
HEPATIC CHANGES INDUCED BY AN AQUEOUS EXTRACT OF ULTRAVIOLET-IRRADIATED LINOLENIC ACID.
Topics: alpha-Linolenic Acid; Autoradiography; Chemical and Drug Induced Liver Injury; Fatty Acids; Fatty Ac | 1964 |
FOLIC ACID DEFICIENCY AND HEPATIC DNA SYNTHESIS.
Topics: Avitaminosis; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; Folic Aci | 1964 |
Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine.
Topics: Acetylcysteine; Animals; Apoptosis; Azathioprine; Caspase 3; Caspases; Cell Survival; Cytochromes c; | 2004 |
Diverse gene expression pattern during 5-fluorouridine-induced apoptosis.
Topics: Analysis of Variance; Apoptosis; Cell Survival; Cluster Analysis; Colorectal Neoplasms; Flow Cytomet | 2005 |
Crystals cause acute necrotic cell death in renal proximal tubule cells, but not in collecting tubule cells.
Topics: Animals; Apoptosis; Calcium Oxalate; Crystallization; Culture Media; Dinoprostone; Dogs; Humans; Hyd | 2005 |
Oxalate is toxic to renal tubular cells only at supraphysiologic concentrations.
Topics: Animals; Apoptosis; Calcium Oxalate; Cell Count; Cell Line; Crystallization; Dinoprostone; Dogs; Dos | 2005 |
Modeling suppression of cell death by Bcl-2 over-expression in myeloma NS0 6A1 cells.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Computational Biology; Gene Expression Regul | 2006 |
Cell death in response to antimetabolites directed at thymidylate synthase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bl | 2008 |
Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Electric Stimulation; Fema | 2007 |
YSK2821, a newly synthesized indoledione derivative, inhibits cell proliferation and cell cycle progression via the cell cycle-related proteins by regulating phosphatidylinositol-3 kinase cascade in vascular smooth muscle cells.
Topics: Apoptosis; Blotting, Western; Cell Count; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Prolifer | 2008 |
Behaviour and fate of a buried graft of small intestine. An experimental study.
Topics: Acid Phosphatase; Animals; Autoradiography; Bile Ducts; Dogs; Duodenum; Epithelium; Galactosidases; | 1967 |
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats.
Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; gamma-Glutamyltransferase; Liver; Liver Neoplas | 1984 |
Population dynamics of arterial cells during atherogenesis. XIII. Mitogenic and cytotoxic effects of a hyperlipidemic (HL) diet on cells in advanced lesions in the abdominal aortas of swine fed an HL diet for 270-345 days.
Topics: Aging; Animals; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Cell Survival; Cholesterol; Die | 1983 |
DNA in cytosol fractions obtained by differential centrifugation of homogenates of rapidly growing liver tumors.
Topics: Animals; Cell Nucleus; Cell Separation; Centrifugation; Cytosol; DNA; DNA, Neoplasm; Female; Hydroxy | 1984 |
Radiation induced alterations in rabbit aortic prostacyclin formation.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Dose-Response Relationship, Radiation; Epoprostenol; Nec | 1982 |
Pulmonary toxicity of methylcyclopentadienyl manganese tricarbonyl: nonciliated bronchiolar epithelial (Clara) cell necrosis and alveolar damage in the mouse, rat, and hamster.
Topics: Animals; Bronchi; Cricetinae; DNA; Epithelium; Female; Male; Manganese Poisoning; Mesocricetus; Mice | 1982 |
An in vivo double labelling study of the subsequent fate of cells arrested in metaphase by vincristine in the JB-1 mouse ascites tumour.
Topics: Animals; Cell Cycle; Cell Survival; Female; Interphase; Metaphase; Mice; Mitosis; Necrosis; Neoplasm | 1980 |
Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol.
Topics: 1-Propanol; alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Biomarkers; Cell Division; Desmin; | 1995 |
Maintenance of the gliding surface of tendon autografts in dogs.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Dogs; Necrosis; Scintillation Counting; Tend | 1994 |
Analysis of the cell death in the mucoid epithelium of mouse stomach.
Topics: Animals; Apoptosis; Autoradiography; Carbohydrate Metabolism; Cell Differentiation; Cell Nucleus; Cy | 1994 |
Active and passive mechanisms of [fluorine-18] fluorodeoxyglucose uptake by proliferating and prenecrotic cancer cells in vivo: a microautoradiographic study.
Topics: Animals; Autoradiography; Cell Cycle; Cell Division; Deoxyglucose; DNA, Neoplasm; Female; Fluorine R | 1994 |
Wound healing process in the portio vaginalis uteri after CO2-laser treatment.
Topics: Cervix Uteri; DNA; Epithelium; Female; Humans; Hydroxyproline; Hyperplasia; Laser Therapy; Necrosis; | 1993 |
Experimentally induced laminar necrosis, status verrucosus, focal cortical dysplasia reminiscent of microgyria, and porencephaly in the rat.
Topics: Animals; Animals, Newborn; Autoradiography; Biomarkers; Brain; Cerebral Cortex; Disease Models, Anim | 1993 |
The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Cell Count; Cell Line; Cell Survival; Epithelial Cells; Huma | 1998 |
Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Bilirubin; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, | 2000 |
Cytotoxicity of myeloma light chains in cultured human kidney proximal tubule cells.
Topics: Apoptosis; Cell Death; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Immunologic; | 2000 |
Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro.
Topics: Antibodies, Monoclonal; Cell Division; Central Nervous System Neoplasms; Drug Screening Assays, Anti | 2000 |
Enhanced inhibition of virus DNA synthesis in hepatocytes by trifluorothymidine coupled to asialofetuin.
Topics: alpha-Fetoproteins; Animals; Bone Marrow; Deoxycytidine; DNA; DNA, Viral; Ectromelia virus; Ectromel | 1979 |
Ultrastructure of 1,2-dimethylhydrazine-induced adenocarcinomas in rat colon.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Nucleus; Colonic Neop | 1978 |
Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate.
Topics: Animals; Biliary Tract; Chenodeoxycholic Acid; Cholic Acids; Common Bile Duct; Deoxycholic Acid; Dos | 1978 |
[The topography of rat liver cell necrosis and proliferation after sublethal phalloidinintoxication of adult and newborn rats (author's transl)].
Topics: Animals; Animals, Newborn; Chemical and Drug Induced Liver Injury; Hemorrhage; Liver; Liver Regenera | 1978 |
Skeletal muscle regeneration in myopathic hamsters of strain BIO 8262.
Topics: Animals; Autoradiography; Cricetinae; Muscles; Muscular Diseases; Necrosis; Regeneration; Thymidine; | 1976 |
7,12-DMBA induced rat mammary tumour studied for hormonal responsiveness in vitro. 2. Organ cultures.
Topics: Animals; Benz(a)Anthracenes; Cell Division; Cell Survival; Depression, Chemical; DNA, Neoplasm; Estr | 1975 |
Preliminary observations on the mitogenic effect of cyclopropenoid fatty acids on rat pancreas.
Topics: Animals; Cell Nucleus; Cyclopropanes; DNA; Dose-Response Relationship, Drug; Endoplasmic Reticulum; | 1975 |
[Acute cell death in various sections of the gastrointestinal tract in DNA synthesis inhibition].
Topics: Animals; Autoradiography; Cell Survival; Digestive System; DNA; Dose-Response Relationship, Drug; Dr | 1975 |
The nature of the embryo-protective interaction of propyl gallate with hydroxyurea.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Embryo, Mammalian; Female; Hydroxyurea; Injections; Necro | 1990 |
Modulation of O6-methylguanine-DNA methyltransferase in rat and hamster liver after treatment with dimethylnitrosamine.
Topics: Animals; Cricetinae; Dimethylnitrosamine; DNA; Dose-Response Relationship, Drug; Kinetics; Liver; Ma | 1990 |
Minoxidil stimulates mouse vibrissae follicles in organ culture.
Topics: Animals; Cell Differentiation; Cysteine; Epidermis; Glycine; Keratins; Mice; Minoxidil; Necrosis; Or | 1989 |
Morphological, biochemical and autoradiographic studies of pancreatic acinar cell necrosis and its regeneration induced by 4-hydroxyaminoquinoline-1-oxide in rats.
Topics: 4-Hydroxyaminoquinoline-1-oxide; Aminoquinolines; Animals; Autoradiography; Male; Necrosis; Pancreas | 1989 |
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
Topics: Animals; Antibodies, Monoclonal; Autoradiography; Cardiomegaly; DNA; DNA Replication; Fibrosis; Hear | 1989 |
[Transition of oxic cells to hypoxic cells in a murine squamous cell carcinoma].
Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Idoxuridine; Iodine Radioisotopes; | 1989 |
Necrotising myopathy and zidovudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Male; Muscular Diseases; Necrosis; Thymid | 1988 |
Evaluation of fluorescein diacetate for flow cytometric determination of cell viability in orthopaedic research.
Topics: Animals; Cartilage, Articular; Cell Survival; Doxorubicin; Evaluation Studies as Topic; Flow Cytomet | 1988 |
Effects of polymethylmethacrylate exposure upon macrophages.
Topics: Animals; Cytotoxicity, Immunologic; DNA; Macrophages; Methylmethacrylates; Necrosis; Thymidine; Tumo | 1988 |
The fate of hypodermis after liposuction surgery.
Topics: Adipose Tissue; Adult; Autoradiography; Epidermis; Female; Fibrosis; Humans; Lipectomy; Necrosis; Sk | 1988 |
Reutilization of 125I-UdR during growth of a solid mammary carcinoma: implications for the 125I-UdR loss technique.
Topics: Adenocarcinoma; Animals; Cell Survival; Idoxuridine; Iodine Radioisotopes; Male; Mammary Neoplasms, | 1987 |
Amelioration of carbon tetrachloride-induced hepatic necrosis by post-toxicant treatment with cystamine.
Topics: Administration, Oral; Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride; Cystamine; DNA; | 1986 |
Histochemical and cellular changes induced in the rabbit knee joint by an intraarticular implantation of a sheet of polyethylene.
Topics: Animals; Bone and Bones; Cartilage, Articular; Cell Survival; Disease Models, Animal; Foreign-Body R | 1985 |
Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Cell Cycle; Estradiol; Female; Humans; Lymph Nodes; Middl | 1986 |
Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function.
Topics: Acute Kidney Injury; Autoradiography; Drug Resistance; Gentamicins; Glomerular Filtration Rate; Hist | 1986 |
Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.
Topics: Animals; Autoradiography; Capillaries; Connective Tissue; Fibroblasts; Kinetics; Mammary Neoplasms, | 1970 |
[Light microscopic and autoradiographic studies on the cellular reaction of the liver after catgut implantation].
Topics: Animals; Autoradiography; Chromium; DNA; Liver; Mice; Necrosis; Protein Biosynthesis; Sutures; Thymi | 1970 |
Lasiocarpine: factors influencing its toxicity and effects on liver cell division.
Topics: Acetates; Alkaloids; Amides; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Dealkylat | 1971 |
Intracellular replication of infectious pancreatic necrosis virus.
Topics: Acridines; Animals; Cells, Cultured; Cytoplasm; DNA; Fibroblasts; Fish Diseases; Fishes; Inclusion B | 1972 |
[Histological and autoradiographic investigations of the galactosamine induced hepatitis of the rat].
Topics: Animals; Autoradiography; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; DNA; Hep | 1969 |
[Autoradiographic investigation of proliferation and polyploidization during CCl4-induced liver regeneration in mice (author's transl)].
Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Cell Division; Liver; Liver Regeneration; | 1973 |
The cell cycles of three transplantable Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Liver Neoplasms; Mitosis; Necro | 1970 |
Cell proliferation and tumor growth in hepatomas 3924A.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Connective Tissue; Female; Liver Neoplasms; Mit | 1971 |
Behaviour of Wilms tumour and normal metanephros in organ culture.
Topics: Age Factors; Autoradiography; Blood Vessels; Cell Differentiation; Cell Membrane; Cell Survival; Cel | 1974 |
Oxygen toxicity in the newborn. Necrotizing bronchiolitis in mice exposed to 100 per cent oxygen.
Topics: Animals; Animals, Newborn; Bronchi; Bronchitis; Cilia; Endoplasmic Reticulum; Lung; Mice; Mice, Inbr | 1974 |
Organ culture of benign nodular hyperplasia of human prostate in chemically-defined medium.
Topics: Aged; Autoradiography; Culture Media; Demecolcine; DNA; Histological Techniques; Humans; Hyperplasia | 1973 |
[Effect of a second CCl 4 -intoxication on CCl 4 -damaged mouse liver].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Nucleus; Chemic | 1972 |
Cell renewal in aortic necrosis following orthostatic collapse. An experimental autoradiographic study in the rabbit using 3 H-thymidine.
Topics: Animals; Aortic Diseases; Autoradiography; Endothelium; Hypotension, Orthostatic; Male; Muscle, Smoo | 1973 |
Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative.
Topics: Animals; Antigens, Neoplasm; Autoradiography; Cell Line; Cell Survival; Cells, Cultured; Computers; | 1972 |
Observations on the cold water treatment of cutaneous burns.
Topics: Animals; Back; Burns; Cell Nucleus; Collagen; Connective Tissue; Connective Tissue Cells; Cryosurger | 1972 |
Mitochondrial proliferation within the nephron. I. Comparison of mitochondrial hyperplasia of tubular regeneration with compensatory hypertrophy.
Topics: Animals; Autoradiography; Cell Nucleus; DNA, Mitochondrial; Epithelial Cells; Hyperplasia; Hypertrop | 1973 |
A quantitative morphological analysis of the response of a transplantable rat fibrosarcoma to cyclophosphamide.
Topics: Animals; Cell Nucleus; Cyclophosphamide; Cytoplasm; Erythrocytes; Fibrosarcoma; Leukocytes; Mitosis; | 1973 |
Ultrastructural and biochemical changes induced in mouse epidermis by a hyperplastic agent, ethylphenylpropiolate.
Topics: Animals; Cell Differentiation; Cell Division; Cell Nucleolus; Chromatin; Cytoplasm; DNA; Endoplasmic | 1973 |
Decreased toxicity of dimethylnitrosamine in rats after treatment with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylamines; DNA; Kidney; | 1973 |
Liver regeneration and uraemia.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Lectins; Liver; Liver Re | 1973 |
Response of the adult newt ventricle to injury.
Topics: Animals; Autoradiography; Blood Coagulation; DNA Replication; Endocardium; Heart Injuries; Heart Ven | 1974 |
[Autoradiographic studies with H3-thymidine in the rat spleen after cryonecrosis].
Topics: Animals; Autoradiography; Cell Division; Cicatrix; Cryosurgery; Freezing; Granulation Tissue; Necros | 1974 |
Experimental aortic intimal thickening. I. Morphology and source of intimal cells.
Topics: Animals; Aorta; Autoradiography; Cell Count; Cell Movement; DNA; Electrocoagulation; Endoplasmic Ret | 1974 |
[Wound healing of kidney after cryonecrosis. Autoradiographic investigations with 3H-thymidine on rats (authors transl)].
Topics: Animals; Autoradiography; Fibroblasts; Freezing; Kidney; Kidney Diseases; Kidney Tubules; Leukocytes | 1974 |
Effect of blood flow reversal in liver autotransplants upon the site of hepatocyte regeneration.
Topics: Animals; Autoradiography; Biopsy; Carotid Arteries; DNA; Dogs; Female; Histological Techniques; Jugu | 1968 |
Studies in the diabetic mutant mouse. II. Electron microscopy of pancreatic islets.
Topics: Animals; Autoradiography; Cytoplasmic Granules; Diabetes Mellitus; Disease Models, Animal; Endoplasm | 1970 |
The importance of the regulation for the normal and abnormal development. Experimental investigations on the limb buds of chick embryos.
Topics: Animals; Chick Embryo; Congenital Abnormalities; Electrocoagulation; Embryo, Mammalian; Embryo, Nonm | 1968 |
[Cell proliferation after traumatic injuries of the liver].
Topics: Animals; Autoradiography; Cell Division; Liver; Liver Regeneration; Mice; Necrosis; Thymidine; Triti | 1970 |
Cell cycle studies in the regenerating rat nephron following injury with mercuric chloride.
Topics: Acute Kidney Injury; Animals; DNA; Kidney Tubules; Male; Mercury; Mitosis; Necrosis; Rats; Regenerat | 1972 |
Early effects of cyclophosphamide on mouse bladder epithelium.
Topics: Acute Disease; Animals; Cell Nucleus; Chronic Disease; Cyclophosphamide; Cystitis; DNA; Epithelial C | 1972 |
Age-specific changes in the proliferation of Ehrlich ascites tumor cells grown as solid tumors.
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Survival; DNA, Neoplasm; Female; In Vitro T | 1972 |
[Cell proliferation in cryonecrotic liver].
Topics: Animals; Autoradiography; Cell Division; Fibroblasts; Freezing; Kupffer Cells; Liver; Necrosis; Rats | 1972 |
Effect of hydroxyurea and cytarabine on rodent epidermal cells.
Topics: Animals; Animals, Newborn; Cell Nucleus; Cytarabine; Depression, Chemical; DNA Replication; Hydroxyu | 1971 |
[Reutilization of labeled DNA building blocks in wound healing].
Topics: Animals; Autoradiography; DNA; Granulation Tissue; Liver Diseases; Liver Regeneration; Mice; Necrosi | 1971 |
Effect of a single dose of dimethylnitrosamine on biosynthesis of nucleic acid and protein in rat liver and kidney.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; DNA; Female; Kidney; Kidney Neoplasms; L | 1971 |
The pathogenesis of iron hepatotoxicity.
Topics: Alloxan; Animals; Autoradiography; Blood Glucose; Chemical and Drug Induced Liver Injury; Ethionine; | 1969 |
Nucleic acid synthesis in the regenerating nephron following injury with mercuric chloride.
Topics: Animals; Autoradiography; DNA; Kidney Tubules; Male; Mercury; Microscopy, Electron; Mitomycins; Mito | 1969 |
Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue. 3. Alterations in the thymic-dependent area induced by the passenger lactic dehydrogenase virus.
Topics: Animals; Immunity, Cellular; L-Lactate Dehydrogenase; Lymphocytes; Lymphoid Tissue; Male; Mice; Micr | 1970 |
[Cell proliferation in the partially resected rat liver after acute intoxication by allyl formate].
Topics: Animals; Autoradiography; Cell Division; DNA; Formates; Hepatectomy; Liver; Liver Regeneration; Male | 1971 |
The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour.
Topics: Animals; Autoradiography; Blood Vessels; Female; Growth; Hyperbaric Oxygenation; Hypoxia; Mammary Ne | 1968 |
[Experimental studies on Wernicke's encephalopathy].
Topics: Acute Disease; Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Diseases; Columbidae; Dem | 1968 |
Differential effects of hydroxyurea on survival of proliferating cells in vivo.
Topics: Animals; Cell Biology; Depression, Chemical; DNA; Epithelial Cells; Folic Acid; Hydroxyurea; Intesti | 1969 |
The behavior of explants of psoriasis in vitro.
Topics: Chlorides; Culture Media; Culture Techniques; DNA; Glucosamine; Heparin; Histocytochemistry; Humans; | 1969 |
The effect of necrosis and tumor on the cell kinetics of small bowel.
Topics: Animals; Autoradiography; Cell Division; Cricetinae; Fibrosarcoma; In Vitro Techniques; Jejunum; Nec | 1966 |
Puromycin-induced necrosis of crypt cells of the small intestine of mouse.
Topics: Animals; Antimetabolites; Autoradiography; Cell Division; Cytarabine; Dactinomycin; DNA; Heart; Inte | 1966 |