thymidine has been researched along with Muscular Diseases in 23 studies
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
Excerpt | Relevance | Reference |
---|---|---|
"All oral nucleoside analogues against hepatitis B virus, with an exception of telbivudine, have been reported causing lactic acidosis (LA)." | 8.89 | Lactic acidosis during telbivudine treatment for HBV: a case report and literature review. ( Hu, P; Huang, XY; Jin, JL; Lu, JH; Luo, SS; Weng, XH; Zhang, JM, 2013) |
"Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV)." | 5.39 | Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B. ( Ahn, SH; Han, KH; Kim, EH; Kim, SM; Lee, KH; Park, H, 2013) |
"All oral nucleoside analogues against hepatitis B virus, with an exception of telbivudine, have been reported causing lactic acidosis (LA)." | 4.89 | Lactic acidosis during telbivudine treatment for HBV: a case report and literature review. ( Hu, P; Huang, XY; Jin, JL; Lu, JH; Luo, SS; Weng, XH; Zhang, JM, 2013) |
"Myopathy or neuropathy has been associated with lamivudine/telbivudine therapy in hepatitis B patients." | 3.80 | Lamivudine/telbivudine-associated neuromyopathy: neurogenic damage, mitochondrial dysfunction and mitochondrial DNA depletion. ( Jin, S; Lv, H; Wang, Z; Xu, H; Yuan, Y; Zhang, W; Zheng, L, 2014) |
"Telbivudine (beta-l-2'-deoxythymidine) is an orally administered nucleoside analog drug approved for the treatment of patients with chronic hepatitis B since 2006." | 3.77 | Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis. ( Dang, S; Gao, N; Jia, X; Zhang, X, 2011) |
"A 27 yo male of African origin received telbivudine for hepatitis B during 3 months." | 3.76 | Myotoxicity of telbivudine in pre-existing muscle damage. ( Ay, L; Finsterer, J, 2010) |
"Increased risk of lactic acidosis has also been described for those with impaired liver and renal function taking entecavir." | 2.50 | Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment. ( Fung, J; Lai, CL; Seto, WK; Yuen, MF, 2014) |
"Successful treatment of chronic hepatitis B (CHB) often requires long-term oral nucleoside/nucleotide agents which can be associated with viral resistance, patient non-compliance and adverse effects." | 2.46 | Safety evaluation of telbivudine. ( But, DY; Fung, J; Lai, CL; Yuen, MF, 2010) |
"Telbivudine has also been reported to be associated with myopathy and neuropathy, particularly when used in combination with pegylated interferon." | 2.45 | Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B. ( Fleischer, RD; Lok, AS, 2009) |
"Lamivudine was switched to telbivudine." | 1.42 | Telbivudine in liver transplant recipients: Renal protection does not overcome the risk of polyneuropathy and myopathy. ( Akarca, US; Bademkiran, F; Duman, S; Ersoz, G; Gunsar, F; Karasu, Z; Kose, T; Ozutemiz, O; Sozbilen, M; Turan, I; Yapali, S, 2015) |
"Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV)." | 1.39 | Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B. ( Ahn, SH; Han, KH; Kim, EH; Kim, SM; Lee, KH; Park, H, 2013) |
"6-Mercaptopurine (6-MP) is an adenine antagonist which has been shown to cause skeletal muscle atrophy in neonatal rats." | 1.27 | Investigating the myopathic effects of 6-mercaptopurine on developing skeletal muscle cells in vitro. ( Kaji, H; Yander, G, 1984) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (34.78) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (13.04) | 29.6817 |
2010's | 12 (52.17) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kim, EH | 1 |
Park, H | 1 |
Lee, KH | 1 |
Ahn, SH | 1 |
Kim, SM | 1 |
Han, KH | 1 |
Lee, SW | 1 |
Jang, JH | 1 |
Kim, BJ | 1 |
Jin, JL | 1 |
Hu, P | 1 |
Lu, JH | 1 |
Luo, SS | 1 |
Huang, XY | 1 |
Weng, XH | 1 |
Zhang, JM | 1 |
Fung, J | 2 |
Seto, WK | 1 |
Lai, CL | 2 |
Yuen, MF | 2 |
Xu, H | 1 |
Wang, Z | 1 |
Zheng, L | 1 |
Zhang, W | 1 |
Lv, H | 1 |
Jin, S | 1 |
Yuan, Y | 1 |
Turan, I | 1 |
Yapali, S | 1 |
Bademkiran, F | 1 |
Kose, T | 1 |
Duman, S | 1 |
Sozbilen, M | 1 |
Gunsar, F | 1 |
Ersoz, G | 1 |
Akarca, US | 1 |
Ozutemiz, O | 1 |
Karasu, Z | 1 |
Ambang, T | 1 |
Tan, JS | 1 |
Ong, S | 1 |
Wong, KT | 1 |
Goh, KJ | 1 |
Fleischer, RD | 1 |
Lok, AS | 1 |
But, DY | 1 |
Finsterer, J | 1 |
Ay, L | 1 |
Dang, S | 1 |
Gao, N | 1 |
Zhang, X | 1 |
Jia, X | 1 |
Zou, XJ | 1 |
Jiang, XQ | 1 |
Tian, DY | 1 |
Wang, M | 1 |
Da, Y | 1 |
Cai, H | 1 |
Lu, Y | 1 |
Wu, L | 1 |
Jia, J | 1 |
Hirano, M | 1 |
MartÃ, R | 1 |
Spinazzola, A | 1 |
Nishino, I | 1 |
Nishigaki, Y | 1 |
ButÃ, MA | 1 |
Yander, G | 1 |
Kaji, H | 1 |
Mohr, W | 1 |
Bock, G | 1 |
Lossnitzer, K | 1 |
Helbert, M | 1 |
Fletcher, T | 1 |
Peddle, B | 1 |
Harris, JR | 1 |
Pinching, AJ | 1 |
Schiaffino, S | 1 |
Bormioli, SP | 1 |
Aloisi, M | 1 |
Ofeigsson, OJ | 1 |
Mitchell, R | 1 |
Patrick, RS | 1 |
Currie, S | 2 |
Saunders, M | 2 |
Knowles, M | 2 |
Brown, AE | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection[NCT04248426] | Phase 1 | 88 participants (Actual) | Interventional | 2020-02-05 | Completed | ||
The Effect of Telbivudine on Renal Function and Proteinuria in Patients With Chronic Hepatitis B Infection and Chronic Kidney Diseases[NCT02049736] | 0 participants (Actual) | Interventional | 2013-12-31 | Withdrawn (stopped due to unable to recruit patients) | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
5 reviews available for thymidine and Muscular Diseases
Article | Year |
---|---|
Lactic acidosis during telbivudine treatment for HBV: a case report and literature review.
Topics: Acidosis, Lactic; Adult; Antiviral Agents; Hepatitis B, Chronic; Humans; Male; Mitochondrial Disease | 2013 |
Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.
Topics: Acidosis, Lactic; Adenine; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Dose-Resp | 2014 |
Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Drug Discovery; Early Terminatio | 2009 |
Safety evaluation of telbivudine.
Topics: Adult; Antiviral Agents; Biomarkers; Creatine Kinase; Double-Blind Method; Drug Resistance, Viral; F | 2010 |
[Telbivudine in the treatment of the chronic B hepatitis].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Biomarkers, Pharmacological; Biotransformation; Clinical | 2008 |
18 other studies available for thymidine and Muscular Diseases
Article | Year |
---|---|
Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Creatine Kinase; Electromyography; Hepatitis B, Chronic; Humans; Male; Musc | 2013 |
Dysphagia could be the first presenting symptom of telbivudine-induced myopathy.
Topics: Aged; Antiviral Agents; Deglutition Disorders; Female; Humans; Muscular Diseases; Telbivudine; Thymi | 2013 |
Lamivudine/telbivudine-associated neuromyopathy: neurogenic damage, mitochondrial dysfunction and mitochondrial DNA depletion.
Topics: Adult; Aged, 80 and over; Antiviral Agents; Biopsy; DNA, Mitochondrial; Female; Hepatitis B; Humans; | 2014 |
Telbivudine in liver transplant recipients: Renal protection does not overcome the risk of polyneuropathy and myopathy.
Topics: Aged; Antiviral Agents; Diabetes Mellitus; Drug Substitution; End Stage Liver Disease; Female; Glome | 2015 |
Clinicopathological Features of Telbivudine-Associated Myopathy.
Topics: Aged; Female; Humans; Male; Middle Aged; Muscular Diseases; Telbivudine; Thymidine | 2016 |
Myotoxicity of telbivudine in pre-existing muscle damage.
Topics: Adult; Antiviral Agents; Creatine Kinase; Hepatitis B; Humans; Male; Muscle, Skeletal; Muscular Dise | 2010 |
Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis.
Topics: Acute Kidney Injury; Antiviral Agents; Fatal Outcome; Fibrosis; Hepatitis B; Humans; Male; Middle Ag | 2011 |
Clinical features and risk factors of creatine kinase elevations and myopathy associated with telbivudine.
Topics: Adolescent; Adult; Age Distribution; Aged; Antiviral Agents; Creatine Kinase; Female; Hepatitis B, C | 2011 |
Telbivudine myopathy in a patient with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Hepatitis B, Chronic; Humans; Male; Muscular Diseases; Telbivudine; Thymidi | 2012 |
Thymidine phosphorylase deficiency causes MNGIE: an autosomal recessive mitochondrial disorder.
Topics: Blotting, Southern; Brain Diseases; Chromatography, High Pressure Liquid; Genes, Recessive; Genetic | 2004 |
Investigating the myopathic effects of 6-mercaptopurine on developing skeletal muscle cells in vitro.
Topics: Animals; Cell Survival; Chick Embryo; DNA; In Vitro Techniques; Leucine; Mercaptopurine; Microtubule | 1984 |
Skeletal muscle regeneration in myopathic hamsters of strain BIO 8262.
Topics: Animals; Autoradiography; Cricetinae; Muscles; Muscular Diseases; Necrosis; Regeneration; Thymidine; | 1976 |
Necrotising myopathy and zidovudine.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Humans; Male; Muscular Diseases; Necrosis; Thymid | 1988 |
Zidovudine-associated myopathy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Humans; Muscular Diseases; Thymidine; Zidovudi | 1988 |
Cell proliferation in rat skeletal muscle during early stages of compensatory hypertrophy.
Topics: Animals; Autoradiography; Cell Count; Cell Division; Cell Nucleus; Epithelial Cells; Fibroblasts; Hy | 1972 |
Observations on the cold water treatment of cutaneous burns.
Topics: Animals; Back; Burns; Cell Nucleus; Collagen; Connective Tissue; Connective Tissue Cells; Cryosurger | 1972 |
Immunological aspects of polymyositis. The in vitro activity of lymphocytes on incubation with muscle antigen and with muscle cultures.
Topics: Adolescent; Adult; Aged; Animals; Antigens; Antilymphocyte Serum; Child, Preschool; Culture Techniqu | 1971 |
Immunological aspects of systemic sclerosis in vitro activity of lymphocytes from patients with the disorder.
Topics: Adult; Animals; Antigens; Biopsy; Collagen; Culture Techniques; Cytotoxicity Tests, Immunologic; Der | 1971 |